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ARWR Should I Buy

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Intellectia

Should You Buy Arrowhead Pharmaceuticals Inc (ARWR) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
69.510
1 Day change
2.25%
52 Week Range
76.760
Analysis Updated At
2026/04/17
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Arrowhead Pharmaceuticals Inc (ARWR) is not a strong buy at the moment for a beginner investor with a long-term focus. While the technical indicators show some bullish trends, the lack of significant positive catalysts, mixed analyst ratings, and weak financial performance in the latest quarter suggest caution. The investor should monitor the stock for future developments, particularly the Phase 3 data expected in Q3 2026, which could unlock value.

Technical Analysis

The technical indicators show a mixed picture. The MACD is positive and contracting, indicating a potential bullish trend. The RSI is neutral at 62.511, and moving averages are bullish with SMA_5 > SMA_20 > SMA_200. Key support is at 60.486, and resistance is at 70.365. However, the stock has declined by 4.19% in the regular market session, suggesting some short-term weakness.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

The low put-call ratios indicate a bullish sentiment in the options market, but the implied volatility percentile is low at 13.2, suggesting limited near-term price movement.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
4
Buy
9

Positive Catalysts

  • Analysts from BofA and H.C. Wainwright maintain a Buy rating with price targets of $81 and $100, respectively, citing potential value unlock from APOC3 sHTG opportunity and obesity growth pillar.

  • The stock has a 90% chance of gaining 10.93% in the next month based on historical patterns.

Neutral/Negative Catalysts

  • Mixed competitor data and questions around INHBE expectations have raised concerns, as highlighted by Leerink.

  • Financial performance in Q1 2026 shows a significant drop in net income (-117.80% YoY) and EPS (-115.83% YoY), despite a massive revenue increase.

Financial Performance

In Q1 2026, revenue increased significantly by 10461.32% YoY to $264.03M. However, net income dropped by -117.80% YoY to $30.81M, and EPS fell by -115.83% YoY to $0.22. Gross margin remained stable at 100%. The financials indicate strong revenue growth but poor profitability.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analyst sentiment is mixed. BofA and H.C. Wainwright maintain a Buy rating with high price targets, while Morgan Stanley and Leerink are more cautious with Market Perform and Equal Weight ratings. Price targets range from $78 to $101, with a focus on upcoming Phase 3 data as a key catalyst.

Wall Street analysts forecast ARWR stock price to rise
11 Analyst Rating
Wall Street analysts forecast ARWR stock price to rise
8 Buy
3 Hold
0 Sell
Moderate Buy
Current: 67.980
sliders
Low
35
Averages
82
High
110
Current: 67.980
sliders
Low
35
Averages
82
High
110
BofA
Buy
maintain
$84 -> $81
AI Analysis
2026-03-26
Reason
BofA
Price Target
$84 -> $81
AI Analysis
2026-03-26
maintain
Buy
Reason
BofA lowered the firm's price target on Arrowhead (ARWR) to $81 from $84 and keeps a Buy rating on the shares. Arrowhead shares fell modestly on mixed competitor INHBE data, though the update appears largely priced in, the analyst tells investors in a research note. The core thesis remains centered on value unlock from the APOC3 sHTG opportunity ahead of the Phase 3 Shasta-3/4 readouts in 3Q26, with expectations that Arrowhead and Ionis Pharmaceuticals (IONS) will split the market and benefit from growing peak sales potential, the firm says.
Leerink
Mani Foroohar
Market Perform
maintain
$8.5B
2026-03-26
Reason
Leerink
Mani Foroohar
Price Target
$8.5B
2026-03-26
maintain
Market Perform
Reason
Leerink analyst Mani Foroohar notes that Wave Life Sciences' (WVE) updated Phase 1 WVE-007 data showed placebo-adjusted visceral fat loss at the 240mg dose, but total fat mass and lean mass stayed largely consistent and body weight modestly improved. Comparisons between Wave and Arrowhead (ARWR) data are impaired by small numbers of patients, differences in baseline, and other factors, but today's update and the greater than 50% fall in Wave's stock price "highlights the degree of optimism baked into INHBE expectations" and brings questions the firm previously raised related to Arrowhead "back to center stage," the analyst tells investors. The firm, which adds that it is not surprised to see Arrowhead down about 2% as material obesity value is baked in at an $8.5B market cap, has a Market Perform rating on Arrowhead shares.
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