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AGEN Overview

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$
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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
3.549
Open
3.210
VWAP
3.38
Vol
844.46K
Mkt Cap
113.85M
Low
3.210
Amount
2.85M
EV/EBITDA(TTM)
--
Total Shares
36.14M
EV
433.10M
EV/OCF(TTM)
--
P/S(TTM)
0.80
Agenus Inc. is an immuno-oncology (I-O) company targeting cancer with a comprehensive pipeline of immunological agents. The company is focused on expanding patient populations benefiting from cancer immunotherapy through combination approaches, using a broad repertoire of antibody therapeutics, adoptive cell therapies (through MiNK Therapeutics) and adjuvants. Its I-O portfolio is driven by several platforms and programs, which include multiple antibody discovery platforms, antibody candidate programs, its saponin-based vaccine adjuvant platform, and a pipeline of novel allogeneic invariant natural killer T cell (iNKT) therapies for treating cancer and other immune-mediated diseases, controlled by MiNK. Its antibody candidate programs include botensilimab (BOT) and balstilimab (BAL) (a PD-1 blocking antibody). The Company has secured committed manufacturing capacity to support BOT+BAL supply needs for its clinical trials, global access programs and future commercialization.
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Events Timeline

(ET)
2026-03-10
07:50:00
Agenus Triggers First $20M Payment with Zydus Lifesciences
select
2025-12-23 (ET)
2025-12-23
08:20:00
Agenus Publishes Ovarian Cancer Trial Results
select
2025-11-18 (ET)
2025-11-18
09:34:08
Agenus names Jose Iglesias as Chief Medical Affairs Officer
select
2025-11-10 (ET)
2025-11-10
08:03:06
Agenus Announces Q3 Earnings Per Share of $1.94, Below Consensus Estimate of $2.20
select
2025-10-17 (ET)
2025-10-17
08:09:17
Agenus Reveals New Findings from its BOT/BAL at ESMO 2025
select
2025-06-17 (ET)
2025-06-17
07:39:36
Agenus, Noetik announce research collaboration to develop predictive biomarkers
select
2025-06-03 (ET)
2025-06-03
08:10:49
Agenus selling U.S. manufacturing facilities to Zydus
select

News

seekingalpha
7.5
12:11 PMseekingalpha
Agenus Triggers First $20M Payment in Zydus Collaboration
  • First Payment Triggered: Agenus announced it has triggered the first $20 million payment under its strategic collaboration with Zydus Lifesciences, based on contracted work orders for CMC and production activities.
  • Potential Revenue: Under the agreement, Agenus may receive up to $50 million in contingent payments, which will support funding for production orders of botensilimab and balstilimab, enhancing its product development capabilities.
  • Operational Activities Initiated: This collaboration marks the start of operational activities between Agenus and Zylidac Bio, the U.S.-based biologics manufacturing arm of Zydus Life Sciences, which is expected to enhance the company's manufacturing capacity.
  • Cash Flow Impact: Through this collaboration, Agenus can support key manufacturing activities without incurring additional capital expenditures, thereby improving its cash flow position and driving future business growth.
Newsfilter
7.5
11:43 AMNewsfilter
Agenus Triggers First Payment in Zydus Collaboration
  • First Payment Activation: Agenus announced the triggering of a $20 million payment under its strategic collaboration with Zydus Lifesciences, based on critical chemistry, manufacturing, and controls (CMC) work orders, marking a significant advancement in the immuno-oncology sector.
  • Production Capacity Enhancement: This payment will support the manufacturing activities for botensilimab (BOT) and balstilimab (BAL), enabling Zydus to initiate its commercial supply and meet the increasing clinical demand and early access programs, thereby enhancing market competitiveness.
  • Strategic Collaboration Significance: The collaboration agreement allows for up to $50 million in contingent payments, enabling Agenus to execute critical manufacturing work without impacting its cash position, ensuring smooth progress of its development and access programs.
  • Global Market Readiness: As reimbursement access continues under France's AAC framework, Agenus, through its partnership with Zydus, is positioned to effectively align with future commercialization needs, ensuring product supply capabilities globally and further solidifying its leadership in the immunotherapy field.
Businesswire
9.5
03-04Businesswire
Agenus to Release Q4 and Year-End 2025 Financial Results
  • Earnings Release Schedule: Agenus is set to announce its fourth quarter and year-end 2025 financial results before the market opens on March 16, 2026, which is expected to provide investors with crucial financial data and future outlook.
  • Strategic Plan Presentation: The company will host a stakeholder briefing webcast in late March to spotlight key strategic plans and data milestones, aiming to enhance investor understanding and confidence in its development direction.
  • Clinical Trial Progress: Approximately 1,200 patients have been treated in phase 1 and phase 2 clinical trials of botensilimab and balstilimab, demonstrating clinical responses across nine metastatic late-line cancers, indicating significant therapeutic potential.
  • New Drug Development Updates: Balstilimab has been evaluated in over 900 patients, showing a favorable tolerability profile and clinical activity, further solidifying Agenus's market position in the immuno-oncology sector.
Newsfilter
9.5
03-04Newsfilter
Agenus Announces Q4 and Year-End 2025 Financial Results Release
  • Financial Results Schedule: Agenus plans to release its Q4 and year-end 2025 financial results before the market opens on March 16, 2026, which is expected to provide investors with crucial financial data and business direction.
  • Strategic Plans Presentation: The company will host a stakeholder briefing webcast in late March to spotlight key strategic plans and data milestones, aiming to enhance investor confidence in the company's future development.
  • Clinical Trial Progress: Approximately 1,200 patients have been treated in phase 1 and phase 2 clinical trials of botensilimab and balstilimab, demonstrating clinical responses across nine metastatic late-line cancers, indicating their potential in cancer immunotherapy.
  • R&D Capabilities: Agenus boasts robust end-to-end development capabilities, including commercial and clinical cGMP manufacturing facilities, research and discovery, and a global clinical operations footprint, showcasing its strong competitive position in the immuno-oncology sector.
Businesswire
2.0
02-19Businesswire
Agenus Unveils New Clinical Data on Botensilimab and Balstilimab
  • Clinical Trial Progress: Agenus presented new data from the C-800-01 trial at the AACR-IO conference, demonstrating clinical activity of botensilimab combined with balstilimab in 341 patients with advanced cancers, particularly in tumor types traditionally unresponsive to therapies, indicating its potential in immuno-oncology.
  • Biomarker Integration: By integrating blood and tumor features, Agenus is establishing a biologically grounded patient stratification approach, especially in microsatellite-stable colorectal cancer, where traditional biomarkers have shown limited predictive value, potentially improving treatment options for patients.
  • Hope for Resistant Patients: The study indicates that the BOT+BAL combination provides durable clinical benefits even in patients resistant to prior PD-1/CTLA-4 therapies, showcasing its application prospects in treating refractory cancers and potentially altering treatment strategies.
  • Future Research Directions: Agenus plans to further explore the mechanisms of botensilimab, particularly in “cold” tumor types, aiming to identify patient subgroups most likely to benefit from next-generation immunotherapies through a more comprehensive view of immune biology.
Newsfilter
2.0
02-19Newsfilter
Agenus' New Therapy Significantly Improves Survival Rates in Cancer Patients
  • Survival Rate Improvement: In a cohort of 341 treated patients, the combination of botensilimab and balstilimab demonstrated a 17% objective response rate and a 26% clinical benefit rate, indicating significant efficacy in treating refractory cancers.
  • Biomarker Integration: The study revealed that integrating blood and tumor features effectively distinguishes patient subgroups with markedly different survival outcomes, achieving a C-index of up to 0.73, showcasing advantages over traditional biomarkers.
  • Immune Response Correlation: Patients experiencing immune-mediated adverse events within the first 12 weeks of treatment had a median overall survival of 22.4 months, significantly higher than the 13.7 months for those without such events, underscoring the importance of immune activation.
  • Clinical Activity in Cold Tumors: Durable clinical benefits were observed in immunologically
Wall Street analysts forecast AGEN stock price to rise
1 Analyst Rating
Wall Street analysts forecast AGEN stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
23.00
Averages
23.00
High
23.00
Current: 0.000
sliders
Low
23.00
Averages
23.00
High
23.00
H.C. Wainwright
H.C. Wainwright
Neutral -> Buy
upgrade
$25
AI Analysis
2025-06-04
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$25
AI Analysis
2025-06-04
upgrade
Neutral -> Buy
Reason
H.C. Wainwright upgraded Agenus to Buy from Neutral with a $25 price target after the company entered into a strategic collaboration with Indian multinational pharmaceutical company Zydus Lifesciences. The definitive partnership is valued at up to $141M and is aimed at accelerating the clinical development of botensilimab and balstilimab while also securing scaled manufacturing both domestically and outside the U.S., the analyst tells investors in a research note. Th firm says that given Agenus' commitment to reducing its cash burn and the capital provided from this partnership, it now believes the company has sufficient funding to advance botensilimab and balstilimab through a Phase 3 trial initiating in the second half of 2025.
Baird
Baird
Neutral
maintain
$4 -> $6
2025-06-04
Reason
Baird
Baird
Price Target
$4 -> $6
2025-06-04
maintain
Neutral
Reason
Baird raised the firm's price target on Agenus to $6 from $4 and keeps a Neutral rating on the shares. The firm updatedits model following the receipt of ts $91M upfront payment from its strategic collaboration with Zydus.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for AGEN
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Valuation Metrics

The current forward P/E ratio for Agenus Inc (AGEN.O) is 24.53, compared to its 5-year average forward P/E of -0.89. For a more detailed relative valuation and DCF analysis to assess Agenus Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-0.89
Current PE
24.53
Overvalued PE
14.34
Undervalued PE
-16.12

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.69
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.69
Undervalued EV/EBITDA
-2.08

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
5.00
Current PS
0.54
Overvalued PS
10.35
Undervalued PS
-0.36

Financials

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Frequently Asked Questions

What is Agenus Inc (AGEN) stock price today?

The current price of AGEN is 3.37 USD — it has increased 6.98

What is Agenus Inc (AGEN)'s business?

Agenus Inc. is an immuno-oncology (I-O) company targeting cancer with a comprehensive pipeline of immunological agents. The company is focused on expanding patient populations benefiting from cancer immunotherapy through combination approaches, using a broad repertoire of antibody therapeutics, adoptive cell therapies (through MiNK Therapeutics) and adjuvants. Its I-O portfolio is driven by several platforms and programs, which include multiple antibody discovery platforms, antibody candidate programs, its saponin-based vaccine adjuvant platform, and a pipeline of novel allogeneic invariant natural killer T cell (iNKT) therapies for treating cancer and other immune-mediated diseases, controlled by MiNK. Its antibody candidate programs include botensilimab (BOT) and balstilimab (BAL) (a PD-1 blocking antibody). The Company has secured committed manufacturing capacity to support BOT+BAL supply needs for its clinical trials, global access programs and future commercialization.

What is the price predicton of AGEN Stock?

Wall Street analysts forecast AGEN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for AGEN is23.00 USD with a low forecast of 23.00 USD and a high forecast of 23.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Agenus Inc (AGEN)'s revenue for the last quarter?

Agenus Inc revenue for the last quarter amounts to 30.23M USD, increased 20.40

What is Agenus Inc (AGEN)'s earnings per share (EPS) for the last quarter?

Agenus Inc. EPS for the last quarter amounts to 1.94 USD, decreased -162.99

How many employees does Agenus Inc (AGEN). have?

Agenus Inc (AGEN) has 316 emplpoyees as of March 10 2026.

What is Agenus Inc (AGEN) market cap?

Today AGEN has the market capitalization of 113.85M USD.