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AGEN Overview

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$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
4.800
Open
4.700
VWAP
4.70
Vol
827.40K
Mkt Cap
183.93M
Low
4.520
Amount
3.89M
EV/EBITDA(TTM)
--
Total Shares
38.40M
EV
497.92M
EV/OCF(TTM)
--
P/S(TTM)
1.26
Agenus Inc. is an immuno-oncology (I-O) company targeting cancer with a comprehensive pipeline of immunological agents. The company is focused on expanding patient populations benefiting from cancer immunotherapy through combination approaches, using a broad repertoire of antibody therapeutics, adoptive cell therapies (through MiNK Therapeutics) and adjuvants. Its I-O portfolio is driven by several platforms and programs, which include multiple antibody discovery platforms, antibody candidate programs, its saponin-based vaccine adjuvant platform, and a pipeline of novel allogeneic invariant natural killer T cell (iNKT) therapies for treating cancer and other immune-mediated diseases, controlled by MiNK. Its antibody candidate programs include botensilimab (BOT) and balstilimab (BAL) (a PD-1 blocking antibody). The Company has secured committed manufacturing capacity to support BOT+BAL supply needs for its clinical trials, global access programs and future commercialization.
Show More

Events Timeline

(ET)
2026-04-17
16:50:00
Agenus Presents BOT and BAL Combination Therapy Data at Cancer Research Meeting
select
2026-04-01 (ET)
2026-04-01
07:40:00
Agenus Enrolls First Patient in Landmark BATTMAN Trial
select
2026-03-10 (ET)
2026-03-10
07:50:00
Agenus Triggers First $20M Payment with Zydus Lifesciences
select
2025-12-23 (ET)
2025-12-23
08:20:00
Agenus Publishes Ovarian Cancer Trial Results
select
2025-11-18 (ET)
2025-11-18
09:34:08
Agenus names Jose Iglesias as Chief Medical Affairs Officer
select
2025-11-10 (ET)
2025-11-10
08:03:06
Agenus Announces Q3 Earnings Per Share of $1.94, Below Consensus Estimate of $2.20
select
2025-10-17 (ET)
2025-10-17
08:09:17
Agenus Reveals New Findings from its BOT/BAL at ESMO 2025
select
2025-06-17 (ET)
2025-06-17
07:39:36
Agenus, Noetik announce research collaboration to develop predictive biomarkers
select

News

Newsfilter
9.0
04-17Newsfilter
New Therapy Shows Significant Efficacy in Gastroesophageal Cancer
  • Significant Disease Control: A clinical trial for gastroesophageal cancer combining botensilimab (BOT), balstilimab (BAL), and agenT-797 demonstrated a 77% disease control rate, with long-term survival exceeding 20 months in a subset of heavily pretreated patients, indicating the potential of this combination therapy in refractory cases.
  • Improved Survival Rates: Patients receiving induction therapy had a median progression-free survival (PFS) of 6.9 months compared to 3.5 months for those without induction, with a hazard ratio (HR) of 0.19 and a p-value of 0.015, underscoring the importance of immune activation and treatment sequencing.
  • Enhanced Long-Term Survival: In the induction cohort, 43% of patients were alive at both 12 and 18 months, compared to only 20% and 0% in the non-induction group, highlighting the effectiveness of the induction strategy in improving long-term survival outcomes.
  • Insights into Immune Mechanisms: The study revealed that the combination of BOT, BAL, and agenT-797 significantly promoted intratumoral T cell and dendritic cell infiltration, leading to the formation of organized tertiary lymphoid structures, providing crucial insights for further exploration of the biological basis of this therapy.
NASDAQ.COM
9.5
04-03NASDAQ.COM
Agenus Shows Remarkably Improving Earnings Outlook
  • Earnings Estimate Revisions: Analysts have raised their earnings estimates for Agenus, projecting a quarterly EPS of $1.95, reflecting a remarkable 289.3% increase from the previous year, indicating a significant enhancement in the company's profitability that could drive further stock price appreciation.
  • Zacks Rank Upgrade: Due to the positive revisions in earnings estimates, Agenus currently holds a Zacks Rank #1 (Strong Buy), a rating tool that has demonstrated an average annual return of 25% since 2008, showcasing strong investment potential.
  • Full-Year Earnings Outlook: The full-year EPS estimate for Agenus stands at $1.30, representing a 151.8% increase from last year, with no negative revisions in the past month, reflecting strong analyst confidence in the company's future performance.
  • Stock Price Uptrend: Over the past four weeks, Agenus's stock has risen by 14%, closely tied to the upward revisions in earnings estimates, suggesting that further upside potential remains, making it a candidate for investors to consider adding to their portfolios.
NASDAQ.COM
6.5
04-03NASDAQ.COM
Zacks Premium Empowers Confident Investing for All
  • Investor Confidence Boost: Zacks Premium offers daily updates of the Zacks Rank and industry rankings, aiding investors in making more informed decisions, thereby enhancing confidence and increasing market participation.
  • Style Scoring System: The Zacks Style Scores rate stocks from A to F based on value, growth, and momentum characteristics, helping investors identify the best stocks likely to outperform the market in the next 30 days, thus improving investment success rates.
  • Strong Performance Returns: Since 1988, stocks with a Zacks Rank of #1 have produced an average annual return of +23.93%, more than double that of the S&P 500, demonstrating their effectiveness and reliability in portfolio construction.
  • Potential Stock Recommendations: Agenus (AGEN) is rated Zacks Rank #1, with a 14% price increase over the past four weeks and an upward revision of its earnings estimate to $1.30 per share for fiscal 2026, indicating strong growth potential and warranting investor attention.
Newsfilter
9.0
04-01Newsfilter
Agenus Launches Landmark Global Phase 3 Clinical Trial
  • Trial Launch: Agenus announced the enrollment of the first patient in the BATTMAN (CO.33) trial, evaluating the immunotherapy combination of BOT and BAL in refractory microsatellite stable metastatic colorectal cancer, aiming to enroll approximately 830 patients and complete global enrollment swiftly, reflecting unprecedented enthusiasm from investigators and patients.
  • Collaborative Research Network: The trial is led by the Canadian Cancer Trials Group (CCTG) and spans over 100 sites across Canada, France, Australia, and New Zealand, aiming to provide new treatment options for difficult-to-treat patients and advance the application of immunotherapy in cold tumors.
  • Clear Research Objectives: The BATTMAN trial serves as the registrational-enabling study for BOT+BAL, designed to offer effective immunotherapy solutions for this challenging patient population, potentially transforming outcomes for patients currently lacking effective treatment options.
  • Historic Milestone: The enrollment of the first patient marks a significant milestone for Agenus in the immunotherapy field, with CCTG researchers optimistic about the potential survival extension from doublet immunotherapy, paving the way for future regulatory submissions.
Newsfilter
8.5
03-26Newsfilter
Agenus Hosts 2026 Stakeholder Webcast on Immunotherapy Progress
  • Immunotherapy Progress: Agenus will host a webcast on March 31, 2026, focusing on the advancements of botensilimab and balstilimab, aiming to enhance treatment options for patients with historically treatment-resistant cancers, showcasing the company's ongoing innovation in immuno-oncology.
  • Clinical Data Insights: Chief Medical Officer Steven J. O'Day will discuss the durability and consistency of BOT+BAL across various tumor types, highlighting how these data inform ongoing development and later-stage trials, indicating the company's potential in treating refractory cancers.
  • Patient Access Programs: Kamel Djazouli, Head of Medical Affairs, will provide updates on Agenus' global access programs, particularly the AAC and Named Patient Programs in France, demonstrating how the company supports patients with limited treatment options, thereby enhancing its market competitiveness.
  • Strategic Priorities: Founder and CEO Garo H. Armen will outline key priorities for 2026, emphasizing the urgency of advancing the BOT+BAL program to improve patient quality of life through innovative treatment solutions.
Newsfilter
2.0
03-17Newsfilter
Agenus Introduces Novel Immunotherapy to Extend Survival
  • Innovative Immunotherapy: Agenus announced that preliminary results of the BOT and BAL combination therapy for microsatellite stable colorectal cancer will be presented at the 2026 AACR Annual Meeting, aiming to extend patient survival by reducing reliance on chemotherapy, showcasing the company's cutting-edge exploration in cancer immunotherapy.
  • Clinical Trial Expansion: The BBoPCO study is the first trial assessing BOT+BAL in patients without liver, bone, or brain metastases, marking a significant shift towards early application of immunotherapy, which is expected to improve patient response and quality of life, addressing the urgent need for new treatment options.
  • Market Demand: Colorectal cancer remains a leading cause of cancer-related deaths globally, with rising incidence among younger populations, and the severe side effects of traditional chemotherapy regimens highlight the critical market significance of introducing new therapies.
  • Drug Mechanism: Botensilimab, as an enhanced anti-CTLA-4 antibody, combined with the PD-1 inhibition of balstilimab, aims to activate the immune system targeting traditionally
Wall Street analysts forecast AGEN stock price to rise
1 Analyst Rating
Wall Street analysts forecast AGEN stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
23.00
Averages
23.00
High
23.00
Current: 0.000
sliders
Low
23.00
Averages
23.00
High
23.00
H.C. Wainwright
H.C. Wainwright
Neutral -> Buy
upgrade
$25
AI Analysis
2025-06-04
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$25
AI Analysis
2025-06-04
upgrade
Neutral -> Buy
Reason
H.C. Wainwright upgraded Agenus to Buy from Neutral with a $25 price target after the company entered into a strategic collaboration with Indian multinational pharmaceutical company Zydus Lifesciences. The definitive partnership is valued at up to $141M and is aimed at accelerating the clinical development of botensilimab and balstilimab while also securing scaled manufacturing both domestically and outside the U.S., the analyst tells investors in a research note. Th firm says that given Agenus' commitment to reducing its cash burn and the capital provided from this partnership, it now believes the company has sufficient funding to advance botensilimab and balstilimab through a Phase 3 trial initiating in the second half of 2025.
Baird
Baird
Neutral
maintain
$4 -> $6
2025-06-04
Reason
Baird
Baird
Price Target
$4 -> $6
2025-06-04
maintain
Neutral
Reason
Baird raised the firm's price target on Agenus to $6 from $4 and keeps a Neutral rating on the shares. The firm updatedits model following the receipt of ts $91M upfront payment from its strategic collaboration with Zydus.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for AGEN
Unlock Now

Valuation Metrics

The current forward P/E ratio for Agenus Inc (AGEN.O) is 2.19, compared to its 5-year average forward P/E of 0.31. For a more detailed relative valuation and DCF analysis to assess Agenus Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
0.31
Current PE
2.19
Overvalued PE
12.31
Undervalued PE
-11.69

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.32
Current EV/EBITDA
7.44
Overvalued EV/EBITDA
1.77
Undervalued EV/EBITDA
-2.40

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
4.81
Current PS
1.36
Overvalued PS
10.14
Undervalued PS
-0.52

Financials

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Frequently Asked Questions

What is Agenus Inc (AGEN) stock price today?

The current price of AGEN is 4.79 USD — it has increased 3.23

What is Agenus Inc (AGEN)'s business?

Agenus Inc. is an immuno-oncology (I-O) company targeting cancer with a comprehensive pipeline of immunological agents. The company is focused on expanding patient populations benefiting from cancer immunotherapy through combination approaches, using a broad repertoire of antibody therapeutics, adoptive cell therapies (through MiNK Therapeutics) and adjuvants. Its I-O portfolio is driven by several platforms and programs, which include multiple antibody discovery platforms, antibody candidate programs, its saponin-based vaccine adjuvant platform, and a pipeline of novel allogeneic invariant natural killer T cell (iNKT) therapies for treating cancer and other immune-mediated diseases, controlled by MiNK. Its antibody candidate programs include botensilimab (BOT) and balstilimab (BAL) (a PD-1 blocking antibody). The Company has secured committed manufacturing capacity to support BOT+BAL supply needs for its clinical trials, global access programs and future commercialization.

What is the price predicton of AGEN Stock?

Wall Street analysts forecast AGEN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for AGEN is23.00 USD with a low forecast of 23.00 USD and a high forecast of 23.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Agenus Inc (AGEN)'s revenue for the last quarter?

Agenus Inc revenue for the last quarter amounts to 34.20M USD, increased 27.45

What is Agenus Inc (AGEN)'s earnings per share (EPS) for the last quarter?

Agenus Inc. EPS for the last quarter amounts to -0.31 USD, decreased -84.50

How many employees does Agenus Inc (AGEN). have?

Agenus Inc (AGEN) has 81 emplpoyees as of April 20 2026.

What is Agenus Inc (AGEN) market cap?

Today AGEN has the market capitalization of 183.93M USD.