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AGEN Overview

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$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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ET
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Intellectia

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High
3.500
Open
3.410
VWAP
3.43
Vol
617.26K
Mkt Cap
145.75M
Low
3.300
Amount
2.12M
EV/EBITDA(TTM)
25.90
Total Shares
41.64M
EV
393.41M
EV/OCF(TTM)
--
P/S(TTM)
0.92
Agenus Inc. is an immuno-oncology (I-O) company targeting cancer with a comprehensive pipeline of immunological agents. The company is focused on expanding patient populations benefiting from cancer immunotherapy through combination approaches, using a broad repertoire of antibody therapeutics, adoptive cell therapies (through MiNK Therapeutics) and adjuvants. Its I-O portfolio is driven by several platforms and programs, which include multiple antibody discovery platforms, antibody candidate programs, its saponin-based vaccine adjuvant platform, and a pipeline of novel allogeneic invariant natural killer T cell (iNKT) therapies for treating cancer and other immune-mediated diseases, controlled by MiNK. Its antibody candidate programs include botensilimab (BOT) and balstilimab (BAL) (a PD-1 blocking antibody). The Company has secured committed manufacturing capacity to support BOT+BAL supply needs for its clinical trials, global access programs and future commercialization.
Show More

Events Timeline

(ET)
2026-05-15
16:20:00
Agenus Publishes BOT+BAL Study Data for Treatment-Refractory HCC
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2026-05-11 (ET)
2026-05-11
12:10:00
Major Averages Slightly Higher as Investors Eye Geopolitical Risks
select
2026-05-11
09:00:00
Agenus SEC Investigation Concluded, No Enforcement Action Needed
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2026-05-11
08:50:00
Company Announces 2026 Strategic Priorities
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2026-05-11
08:50:00
Agenus Achieves Major Progress in Q1 2026 Advancing BOT and BAL Programs
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2026-04-21 (ET)
2026-04-21
08:20:00
Agenus Appoints BAP Pharma as Global Partner
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2026-04-17 (ET)
2026-04-17
16:50:00
Agenus Presents BOT and BAL Combination Therapy Data at Cancer Research Meeting
select
2026-04-01 (ET)
2026-04-01
07:40:00
Agenus Enrolls First Patient in Landmark BATTMAN Trial
select
2026-03-10 (ET)
2026-03-10
07:50:00
Agenus Triggers First $20M Payment with Zydus Lifesciences
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News

Newsfilter
9.0
05-21Newsfilter
Noetik's TARIO-2 Platform Reveals Tumor Microenvironment Patterns
  • Significant Clinical Response: Among 113 patients treated with BOT+BAL, the AI-identified subgroup exhibited a 64% response rate compared to just 9% in the remaining cohort, highlighting TARIO-2's potential in identifying patients likely to benefit from treatment.
  • Improved Survival Rates: In the MSS metastatic colorectal cancer cohort without active liver metastases, the AI-identified subgroup had a median overall survival not reached, with a hazard ratio of 0.18, indicating TARIO-2's significant predictive power for survival outcomes.
  • Innovative Technology Application: The TARIO-2 model analyzes standard H&E pathology images to extract biologically relevant tumor microenvironment features, offering a patient stratification strategy that does not rely on complex tissue profiling, which could transform clinical practices.
  • Future Validation Plans: Agenus is set to present these findings at the 2026 ASCO Annual Meeting, aiming to validate TARIO-2 as an image-based biomarker strategy for BOT+BAL, thereby advancing the clinical development of immunotherapy.
Newsfilter
2.0
05-15Newsfilter
Agenus Reports New Data on HCC Treatment
  • Clinical Trial Results: Agenus' Phase 1b trial data reveals that in 19 patients with treatment-refractory hepatocellular carcinoma (HCC), the combination of BOT and BAL achieved an objective response rate of 17%, including one complete response and two partial responses, indicating potential efficacy in this challenging patient population.
  • Survival Analysis: Among 18 efficacy-evaluable patients, the median overall survival was reported at 12.3 months, despite 47% of the cohort having ALBI grade 2 liver function, which typically indicates poorer prognosis, thus highlighting the potential of BOT and BAL in improving survival outcomes.
  • Safety Assessment: The safety profile of BOT and BAL in HCC patients was consistent with prior studies, with 68% of patients experiencing immune-mediated adverse events and no treatment-related deaths, suggesting that the combination is manageable and suitable for further investigation.
  • Future Research Directions: Investigators noted that the BOT and BAL combination demonstrated promising efficacy and manageable safety in post-immunotherapy HCC patients, supporting continued exploration in this area to assess its applicability in a broader patient population.
seekingalpha
9.5
05-08seekingalpha
Agenus Scheduled to Announce Q1 Earnings on May 11
  • Earnings Announcement Timing: Agenus (AGEN) is set to release its Q1 2023 earnings report on May 11 before the market opens, drawing significant attention from investors regarding its performance and future outlook.
  • Earnings Expectations: The consensus EPS estimate stands at $2.10, with revenue expectations at $129.5 million, metrics that could directly influence investor confidence and market sentiment.
  • Historical Performance Review: Over the past year, Agenus has only surpassed EPS and revenue estimates 25% of the time, indicating considerable volatility in its performance, which may affect market expectations for future results.
  • Market Reaction Potential: Given Agenus's inconsistent performance in exceeding expectations, investors should closely monitor the upcoming earnings report to assess its potential impact on stock price and the necessity for strategic adjustments.
Newsfilter
9.5
05-04Newsfilter
Agenus Announces Q1 2026 Financial Results Release Schedule
  • Financial Results Announcement: Agenus plans to release its Q1 2026 financial results before the market opens on May 11, 2026, which is expected to provide investors with the latest insights into the company's financial health, potentially impacting stock price movements.
  • Annual Shareholder Meeting: The company will host a webcast in June in conjunction with its Annual Meeting of Shareholders, focusing on key strategic priorities and upcoming data milestones, aimed at enhancing investor confidence and attracting more attention.
  • Clinical Trial Progress: Approximately 1,200 patients have been treated with botensilimab and balstilimab in phase 1 and phase 2 clinical trials, demonstrating clinical responses across nine metastatic late-line cancers, which may lay the groundwork for the company's future market performance.
  • Development Capabilities: Agenus boasts a comprehensive pipeline of immuno-oncology agents and robust development capabilities, leveraging its clinical and commercial cGMP manufacturing facilities, which may position the company favorably in future market competition.
Newsfilter
9.0
04-17Newsfilter
New Therapy Shows Significant Efficacy in Gastroesophageal Cancer
  • Significant Disease Control: A clinical trial for gastroesophageal cancer combining botensilimab (BOT), balstilimab (BAL), and agenT-797 demonstrated a 77% disease control rate, with long-term survival exceeding 20 months in a subset of heavily pretreated patients, indicating the potential of this combination therapy in refractory cases.
  • Improved Survival Rates: Patients receiving induction therapy had a median progression-free survival (PFS) of 6.9 months compared to 3.5 months for those without induction, with a hazard ratio (HR) of 0.19 and a p-value of 0.015, underscoring the importance of immune activation and treatment sequencing.
  • Enhanced Long-Term Survival: In the induction cohort, 43% of patients were alive at both 12 and 18 months, compared to only 20% and 0% in the non-induction group, highlighting the effectiveness of the induction strategy in improving long-term survival outcomes.
  • Insights into Immune Mechanisms: The study revealed that the combination of BOT, BAL, and agenT-797 significantly promoted intratumoral T cell and dendritic cell infiltration, leading to the formation of organized tertiary lymphoid structures, providing crucial insights for further exploration of the biological basis of this therapy.
NASDAQ.COM
9.5
04-03NASDAQ.COM
Agenus Shows Remarkably Improving Earnings Outlook
  • Earnings Estimate Revisions: Analysts have raised their earnings estimates for Agenus, projecting a quarterly EPS of $1.95, reflecting a remarkable 289.3% increase from the previous year, indicating a significant enhancement in the company's profitability that could drive further stock price appreciation.
  • Zacks Rank Upgrade: Due to the positive revisions in earnings estimates, Agenus currently holds a Zacks Rank #1 (Strong Buy), a rating tool that has demonstrated an average annual return of 25% since 2008, showcasing strong investment potential.
  • Full-Year Earnings Outlook: The full-year EPS estimate for Agenus stands at $1.30, representing a 151.8% increase from last year, with no negative revisions in the past month, reflecting strong analyst confidence in the company's future performance.
  • Stock Price Uptrend: Over the past four weeks, Agenus's stock has risen by 14%, closely tied to the upward revisions in earnings estimates, suggesting that further upside potential remains, making it a candidate for investors to consider adding to their portfolios.
Wall Street analysts forecast AGEN stock price to rise
1 Analyst Rating
Wall Street analysts forecast AGEN stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
23.00
Averages
23.00
High
23.00
Current: 0.000
sliders
Low
23.00
Averages
23.00
High
23.00
H.C. Wainwright
H.C. Wainwright
Neutral -> Buy
upgrade
$25
AI Analysis
2025-06-04
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$25
AI Analysis
2025-06-04
upgrade
Neutral -> Buy
Reason
H.C. Wainwright upgraded Agenus to Buy from Neutral with a $25 price target after the company entered into a strategic collaboration with Indian multinational pharmaceutical company Zydus Lifesciences. The definitive partnership is valued at up to $141M and is aimed at accelerating the clinical development of botensilimab and balstilimab while also securing scaled manufacturing both domestically and outside the U.S., the analyst tells investors in a research note. Th firm says that given Agenus' commitment to reducing its cash burn and the capital provided from this partnership, it now believes the company has sufficient funding to advance botensilimab and balstilimab through a Phase 3 trial initiating in the second half of 2025.
Baird
Baird
Neutral
maintain
$4 -> $6
2025-06-04
Reason
Baird
Baird
Price Target
$4 -> $6
2025-06-04
maintain
Neutral
Reason
Baird raised the firm's price target on Agenus to $6 from $4 and keeps a Neutral rating on the shares. The firm updatedits model following the receipt of ts $91M upfront payment from its strategic collaboration with Zydus.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for AGEN
Unlock Now

Valuation Metrics

The current forward P/E ratio for Agenus Inc (AGEN.O) is 1.52, compared to its 5-year average forward P/E of 0.42. For a more detailed relative valuation and DCF analysis to assess Agenus Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
0.42
Current PE
1.52
Overvalued PE
12.41
Undervalued PE
-11.56

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.17
Current EV/EBITDA
6.23
Overvalued EV/EBITDA
2.16
Undervalued EV/EBITDA
-2.49

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
4.72
Current PS
1.08
Overvalued PS
10.08
Undervalued PS
-0.64

Financials

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Frequently Asked Questions

What is Agenus Inc (AGEN) stock price today?

The current price of AGEN is 3.5 USD — it has increased 2.94

What is Agenus Inc (AGEN)'s business?

Agenus Inc. is an immuno-oncology (I-O) company targeting cancer with a comprehensive pipeline of immunological agents. The company is focused on expanding patient populations benefiting from cancer immunotherapy through combination approaches, using a broad repertoire of antibody therapeutics, adoptive cell therapies (through MiNK Therapeutics) and adjuvants. Its I-O portfolio is driven by several platforms and programs, which include multiple antibody discovery platforms, antibody candidate programs, its saponin-based vaccine adjuvant platform, and a pipeline of novel allogeneic invariant natural killer T cell (iNKT) therapies for treating cancer and other immune-mediated diseases, controlled by MiNK. Its antibody candidate programs include botensilimab (BOT) and balstilimab (BAL) (a PD-1 blocking antibody). The Company has secured committed manufacturing capacity to support BOT+BAL supply needs for its clinical trials, global access programs and future commercialization.

What is the price predicton of AGEN Stock?

Wall Street analysts forecast AGEN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for AGEN is23.00 USD with a low forecast of 23.00 USD and a high forecast of 23.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Agenus Inc (AGEN)'s revenue for the last quarter?

Agenus Inc revenue for the last quarter amounts to 33.74M USD, increased 40.18

What is Agenus Inc (AGEN)'s earnings per share (EPS) for the last quarter?

Agenus Inc. EPS for the last quarter amounts to 1.02 USD, decreased -199.03

How many employees does Agenus Inc (AGEN). have?

Agenus Inc (AGEN) has 81 emplpoyees as of May 30 2026.

What is Agenus Inc (AGEN) market cap?

Today AGEN has the market capitalization of 145.75M USD.