Xeris Biopharma Shares Surge 7.59% as Competitor Corcept's FDA Approval Fails
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 01 2026
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Source: Fool
- Stock Surge: Xeris Biopharma's shares rose 7.59% on Wednesday following the news that competitor Corcept Therapeutics' drug failed to gain FDA approval, reflecting investor confidence in Xeris's existing medication, Recorlev, which is expected to further solidify its market position.
- Market Potential: Analyst Glen Santangelo reiterated a buy rating on Xeris with a $10 price target, highlighting that the addressable market for Cushing's disease could grow from the current $1 billion to $3 billion by 2030, indicating significant growth potential for Xeris in this sector.
- FDA Decision Impact: Corcept's relacorilant was not approved by the FDA due to insufficient evidence of effectiveness, a decision that will reduce competition for Xeris's Recorlev, thereby enhancing its sales outlook.
- Clinical Trial Challenges: Although Corcept has vowed to continue pursuing approval, this will likely require additional clinical trials, potentially delaying its market entry and providing Xeris with more time and space to expand its market share.
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Analyst Views on XERS
Wall Street analysts forecast XERS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for XERS is 11.00 USD with a low forecast of 8.00 USD and a high forecast of 18.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
6 Analyst Rating
5 Buy
1 Hold
0 Sell
Strong Buy
Current: 7.240
Low
8.00
Averages
11.00
High
18.00
Current: 7.240
Low
8.00
Averages
11.00
High
18.00
About XERS
Xeris Biopharma Holdings, Inc. is a biopharmaceutical company focused on improving patient lives by developing and commercializing products across a range of therapies. It has three commercially available products: Recorlev, Gvoke, and Keveyis. Recorlev is for the treatment of endogenous Cushing’s syndrome. Gvoke is a ready-to-use liquid glucagon for the treatment of severe hypoglycemia. Keveyis is a therapy for primary periodic paralysis. It also has a pipeline of development programs led by XP-8121, a phase III-ready, once-weekly subcutaneous injection for hypothyroidism. It is pursuing formulation and development partnerships to apply its XeriSol and XeriJect formulation technologies to enhance the drug delivery and clinical profile of other companies’ proprietary drugs and biologics. Recorlev is a cortisol synthesis inhibitor approved for the treatment of endogenous hypercortisolemia in adults with Cushing's syndrome for whom surgery is not an option or has not been curative.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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Xeris Anticipates 2025 Revenue of $292 Million, Exceeding Guidance
- Revenue Growth: Xeris anticipates total revenue of $292 million for 2025, exceeding the guidance range of $285-$290 million and reflecting a 44% increase from the previous year, indicating strong market demand and product performance.
- Product Performance: Recorlev® achieved net revenue of $45 million in Q4 2025 and $139 million for the full year, demonstrating increasing market acceptance in treating endogenous Cushing's syndrome.
- Patient Base Expansion: By the end of 2025, approximately 700 patients were on Recorlev® therapy, while Gvoke® saw revenue growth of over 13% year-over-year, showcasing the company's success in patient treatment and market penetration.
- Financial Stability: Xeris delivered positive adjusted EBITDA in every quarter, reinforcing the company's financial foundation and positioning it for sustained growth in the future.
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