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CRNX Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

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High
41.325
Open
40.000
VWAP
40.68
Vol
1.10M
Mkt Cap
4.29B
Low
39.710
Amount
44.83M
EV/EBITDA(TTM)
--
Total Shares
104.71M
EV
3.06B
EV/OCF(TTM)
--
P/S(TTM)
476.87
Crinetics Pharmaceuticals, Inc. is a clinical-stage pharmaceutical company focused on the discovery, development and commercialization of therapeutics for rare endocrine diseases and endocrine-related tumors. Its lead development candidate, PALSONIFY (paltusotine), is the first investigational once-daily, oral, selective somatostatin receptor type 2 (SST2) nonpeptide agonist that is in clinical development for acromegaly and carcinoid syndrome associated with neuroendocrine tumors. Its second product candidate is Atumelnant, which is in clinical development for congenital adrenal hyperplasia (CAH) and patients with either Cushing's disease or Ectopic ACTH Syndrome (EAS). Its drug candidates are orally delivered, small molecule new chemical entities resulting from in-house drug discovery efforts, including other programs addressing a variety of endocrine conditions such as hyperparathyroidism, polycystic kidney disease, Graves' disease, thyroid eye disease, diabetes and obesity.
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Events Timeline

(ET)
2026-04-13
09:00:00
ALX Oncology Appoints Jeff Knight as Chief Development and Operating Officer
select
2026-03-26 (ET)
2026-03-26
16:40:00
Crinetics Submits Marketing Authorization Application for Palsonify in Brazil
select
2026-02-26 (ET)
2026-02-26
17:10:00
Crinetics Reports Q4 Revenue of $6.16M, Exceeding Expectations
select
2026-01-22 (ET)
2026-01-22
16:30:00
Crinetics Doses First Patient in BALANCE-CAH Trial
select

News

Globenewswire
5.0
04-15Globenewswire
Neutrolis Appoints New Chief Business & Strategy Officer
  • Leadership Change: Neutrolis has appointed Caren Deardorf as Chief Business & Strategy Officer, tasked with advancing NTR-1011 for autoimmune diseases, indicating the company's strategic focus on clinical pipeline progression.
  • Extensive Industry Experience: Deardorf brings over 30 years of leadership experience in biopharma, having held executive roles at Editas Medicine and Biogen, where she successfully led multiple global product launches, enhancing Neutrolis's market competitiveness.
  • Strategic Vision and Execution: Neutrolis CEO Anthony Aiudi praised Deardorf's commercial acuity and strategic vision, emphasizing that her leadership will be crucial for advancing the company's pipeline and expanding strategic partnerships, signaling future growth potential.
  • Innovative Therapeutic Approach: Neutrolis focuses on developing rapid-acting, non-immunosuppressive therapies targeting Neutrophil Extracellular Traps (NETs), and Deardorf's addition is expected to accelerate the clinical application of this innovative therapy, addressing urgent needs in autoimmune disease patients.
Newsfilter
5.0
04-15Newsfilter
Neutrolis Appoints New Chief Business Officer
  • Leadership Change: Neutrolis has appointed Caren Deardorf as Chief Business & Strategy Officer, tasked with advancing NTR-1011 for autoimmune diseases, marking a significant strategic shift in the company's clinical pipeline development.
  • Extensive Industry Experience: With over 30 years in biopharma leadership, Deardorf previously served as Chief Commercial Officer at Editas Medicine, successfully launching multiple global products, which is expected to provide Neutrolis with valuable market insights and strategic direction.
  • Clear Strategic Goals: Deardorf expressed her commitment to creating shareholder value and addressing unmet patient needs, aligning closely with Neutrolis's mission and indicating potential breakthroughs in autoimmune disease treatment.
  • Innovative Therapeutic Approach: Neutrolis focuses on developing rapid-acting, non-immunosuppressive therapies targeting Neutrophil Extracellular Traps, and Deardorf's leadership is anticipated to accelerate the clinical advancement of this novel therapy, enhancing the company's competitiveness in the biopharma market.
moomoo
5.0
04-08moomoo
Crinetics (CRNX.US) Officer Plans to Sell $3.27 Million in Common Stock via Form 144
  • Stock Sale Announcement: Jeff Knight plans to sell 85,163 shares of Crinetics (CRNX.US) common stock on April 8, with an estimated market value of around $3.27 million.

  • Reduction in Shareholding: Since March 16, 2026, Jeff Knight has reduced his shareholding in Crinetics by 9,911 shares, valued at approximately $370.41K.

NASDAQ.COM
5.0
03-28NASDAQ.COM
Crinetics Pharmaceuticals Director Sells Shares
  • Share Sale Details: On March 12, 2026, Crinetics Pharmaceuticals director Rogerio Vivaldi Coelho sold 5,000 shares for approximately $180,761, reducing his direct ownership to 16,300 shares, indicating a strategic liquidity move rather than a lack of confidence in the company.
  • Market Reaction Analysis: The sale represented 23.47% of Coelho's direct holdings and occurred amidst a 4% decline in share price, suggesting that this transaction was more about liquidity needs than signaling positive business outlook.
  • Financial Performance Overview: Crinetics reported $7.7 million in revenue for 2025, largely driven by the successful launch of its lead drug Palsonify, which generated $5.4 million in its first quarter, highlighting the company's potential in early commercialization.
  • R&D Spending and Market Expansion: Despite R&D expenditures exceeding $330 million, Crinetics is expanding internationally, recently submitting a marketing application for Palsonify in Brazil, which could further enhance growth prospects moving forward.
Fool
5.0
03-28Fool
Crinetics Pharmaceuticals Director Sells 5,000 Shares
  • Sale Overview: Rogerio Vivaldi Coelho, a director at Crinetics Pharmaceuticals, sold 5,000 shares of common stock on March 12, 2026, for approximately $181,000, reducing his direct holdings to 16,300 shares valued at around $595,000 post-transaction.
  • Transaction Context: This sale accounted for 23.47% of Coelho's direct ownership, marking his first public open-market sale, executed automatically under a Rule 10b5-1 trading plan adopted on December 11, 2025, indicating a non-discretionary liquidity management strategy.
  • Market Reaction and Valuation: The shares were sold at a weighted average price of about $36.15, closely aligned with the market close of $36.51 on March 12, 2026, suggesting that the transaction did not significantly impact market pricing, reflecting stability in the stock.
  • Company Growth Prospects: Crinetics Pharmaceuticals generated $7.7 million in revenue for 2025, primarily driven by the successful launch of its lead drug, Palsonify, and despite R&D expenses exceeding $330 million, the company’s international expansion and $1.4 billion in cash post-offering position it well for future growth.
seekingalpha
5.0
03-23seekingalpha
Crinetics Pharmaceuticals COO Resignation and Future Plans
  • Executive Resignation: Crinetics Pharmaceuticals' Chief Development and Operating Officer Jeff Knight will resign effective April 10, 2026, with his responsibilities and team reassigned to other executives, potentially impacting operational efficiency and decision-making processes.
  • Financial Planning: The company outlines a $600 million to $650 million operating expense plan for 2026, aimed at supporting the accelerated launch of PALSONIFY, reflecting its commitment to the market potential of new products.
  • Market Environment: Amid disruptions in the Middle East, Wall Street's focus on oversold mid-cap healthcare stocks has increased, placing Crinetics under greater market pressure and investor scrutiny.
  • Investor Engagement: Crinetics presented at the TD Cowen 46th Annual Health Care Conference, indicating its proactive approach in communicating future strategies and financial health to investors.
Wall Street analysts forecast CRNX stock price to rise
11 Analyst Rating
Wall Street analysts forecast CRNX stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
67.00
Averages
89.40
High
105.00
Current: 0.000
sliders
Low
67.00
Averages
89.40
High
105.00
Citizens
Outperform
to
NULL
downgrade
$105 -> $96
AI Analysis
2026-03-02
Reason
Citizens
Price Target
$105 -> $96
AI Analysis
2026-03-02
downgrade
Outperform
to
NULL
Reason
Citizens lowered the firm's price target on Crinetics to $96 from $105 and keeps an Outperform rating on the shares. Commentary on the Palsonify launch was consistent with management's January preannouncement while the pipeline execution continues at a steady pace, the analyst tells investors in a research note.
Stifel
Alex Thompson
Buy
downgrade
$84 -> $83
2026-02-27
Reason
Stifel
Alex Thompson
Price Target
$84 -> $83
2026-02-27
downgrade
Buy
Reason
Stifel analyst Alex Thompson lowered the firm's price target on Crinetics to $83 from $84 and keeps a Buy rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for CRNX
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Valuation Metrics

The current forward P/E ratio for Crinetics Pharmaceuticals Inc (CRNX.O) is 0.00, compared to its 5-year average forward P/E of -8.26. For a more detailed relative valuation and DCF analysis to assess Crinetics Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-8.26
Current PE
0.00
Overvalued PE
-5.41
Undervalued PE
-11.12

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.36
Current EV/EBITDA
-1.06
Overvalued EV/EBITDA
-2.21
Undervalued EV/EBITDA
-8.50

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
940.85
Current PS
23.19
Overvalued PS
2192.01
Undervalued PS
-310.32

Financials

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Quarterly

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Whales Holding CRNX

A
Artal Group S.A.
Holding
CRNX
+19.34%
3M Return
P
Paradigm Biocapital Advisors LP
Holding
CRNX
+15.48%
3M Return
G
GW&K Investment Management, LLC
Holding
CRNX
+14.40%
3M Return
E
EcoR1 Capital, LLC
Holding
CRNX
+12.59%
3M Return
D
Driehaus Capital Management LLC
Holding
CRNX
+9.72%
3M Return
C
Cormorant Asset Management, LP
Holding
CRNX
+2.63%
3M Return

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Frequently Asked Questions

What is Crinetics Pharmaceuticals Inc (CRNX) stock price today?

The current price of CRNX is 41 USD — it has increased 5.07

What is Crinetics Pharmaceuticals Inc (CRNX)'s business?

Crinetics Pharmaceuticals, Inc. is a clinical-stage pharmaceutical company focused on the discovery, development and commercialization of therapeutics for rare endocrine diseases and endocrine-related tumors. Its lead development candidate, PALSONIFY (paltusotine), is the first investigational once-daily, oral, selective somatostatin receptor type 2 (SST2) nonpeptide agonist that is in clinical development for acromegaly and carcinoid syndrome associated with neuroendocrine tumors. Its second product candidate is Atumelnant, which is in clinical development for congenital adrenal hyperplasia (CAH) and patients with either Cushing's disease or Ectopic ACTH Syndrome (EAS). Its drug candidates are orally delivered, small molecule new chemical entities resulting from in-house drug discovery efforts, including other programs addressing a variety of endocrine conditions such as hyperparathyroidism, polycystic kidney disease, Graves' disease, thyroid eye disease, diabetes and obesity.

What is the price predicton of CRNX Stock?

Wall Street analysts forecast CRNX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CRNX is89.40 USD with a low forecast of 67.00 USD and a high forecast of 105.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Crinetics Pharmaceuticals Inc (CRNX)'s revenue for the last quarter?

Crinetics Pharmaceuticals Inc revenue for the last quarter amounts to 6.16M USD, decreased

What is Crinetics Pharmaceuticals Inc (CRNX)'s earnings per share (EPS) for the last quarter?

Crinetics Pharmaceuticals Inc. EPS for the last quarter amounts to -1.29 USD, increased 46.59

How many employees does Crinetics Pharmaceuticals Inc (CRNX). have?

Crinetics Pharmaceuticals Inc (CRNX) has 594 emplpoyees as of April 19 2026.

What is Crinetics Pharmaceuticals Inc (CRNX) market cap?

Today CRNX has the market capitalization of 4.29B USD.