Akari Therapeutics sets price for 3.13 million ADSs at $0.80 in direct registered offering
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Oct 15 2025
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Definitive Agreement for ADS Sale: Akari Therapeutics has entered into a definitive agreement to sell 3,125,000 American Depositary Shares (ADS) at a price of $0.80 per ADS, with Ladenburg Thalmann & Co. Inc. as the exclusive placement agent.
Concurrent Private Placement and Use of Proceeds: The company will also issue unregistered Series E and F Warrants, and plans to use the net proceeds of approximately $2.5M for working capital, corporate purposes, and R&D focused on cancer treatment, with data to be presented at an upcoming conference.
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Analyst Views on AKTX
Wall Street analysts forecast AKTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for AKTX is 3.33 USD with a low forecast of 1.00 USD and a high forecast of 7.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
3 Analyst Rating
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.254
Low
1.00
Averages
3.33
High
7.00
Current: 0.254
Low
1.00
Averages
3.33
High
7.00
About AKTX
Akari Therapeutics, Plc is a biotechnology company developing precision bifunctional antibody drug conjugates (ADC) for the treatment of cancer. Utilizing its ADC discovery platform, it generates bifunctional ADC candidates and optimizes them based on the desired application to target a range of cancers. Its lead candidate, AKTX-101, targets the TROP2 receptor on cancer cells, and with a proprietary linker, delivers its novel PH1 payload directly into the tumor. PH1 is a novel bifunctional payload that is designed to disrupt RNA splicing within cancer cells, inducing tumor-specific cell death while generating immunostimulatory effects and minimizing off-target toxicity. Its pipeline includes AKTX-101 and AKTX-102, a discovery-stage ADC that pairs PH1 with an undisclosed target antibody. It is pursuing research on two additional novel payloads, such as PH5 and PH6. It also has an ADC Platform for oncology and PHP-303 program for genetic disease, liver disease and inflammation.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Akari Therapeutics Highlights 2025 Progress, Plans First-in-Human Trials in 2026
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- Innovative Drug Platform: The company is leveraging its unique PH1 payload platform to develop next-generation antibody-drug conjugates (ADCs), which have demonstrated compelling preclinical efficacy and safety, potentially transforming cancer treatment paradigms.
- Clinical Trial Plans: Akari plans to initiate its First-in-Human trial by the end of 2026, aiming to validate the efficacy of its lead candidate AKTX-101, which is expected to create new growth opportunities for the company.
- Market Potential: AKTX-101 targets the Trop2 receptor on cancer cells with a proprietary linker, anticipated to significantly enhance therapeutic efficacy and potentially synergize with checkpoint inhibitors, thereby strengthening the company's competitive position in the market.
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Akari Therapeutics Presents ADC Platform and 2026 Strategic Priorities at Biotech Showcase
- Strategic Presentation: Akari Therapeutics' CEO Abizer Gaslightwala will present the company's antibody-drug conjugate (ADC) platform and 2026 strategic priorities at the Biotech Showcase on January 13, 2026, aiming to attract investor interest in its innovative drug development.
- Innovative Drug Development: Akari's lead candidate, AKTX-101, targets the Trop2 receptor on cancer cells with its unique PH1 payload, showing significant effects in inducing cancer cell death and activating the immune system in preclinical studies, potentially offering new hope in cancer treatment.
- Clinical Trial Plans: The company has initiated IND enabling studies for AKTX-101, with plans to start its First-In-Human trial by late 2026 or early 2027, marking a significant step in its development and market potential in oncology.
- Multipronged Target Strategy: In addition to AKTX-101, Akari is advancing AKTX-102, an ADC targeting a novel antigen highly relevant in gastrointestinal and lung cancers, showcasing the company's broad pipeline and research capabilities across multiple cancer treatment areas.
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