Tyra Biosciences Presents Two Abstracts at ASCO GU Symposium
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1 hour ago
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Should l Buy TYRA?
Source: Newsfilter
- Abstract Presentation: Tyra Biosciences announced the acceptance of two abstracts for the 2026 ASCO GU Symposium, focusing on research related to FGFR3-altered metastatic urothelial cancer and low-grade non-muscle invasive bladder cancer, highlighting the company's advancements in FGFR biology.
- Clinical Trial Details: The first abstract pertains to the SURF301 trial, which monitors ctDNA in patients treated with dabogratinib for FGFR3-altered metastatic urothelial cancer, while the second focuses on the SURF302 trial evaluating the efficacy and safety of dabogratinib in low-grade non-muscle invasive bladder cancer patients.
- Conference Schedule: Both studies will be presented during the poster session on February 27, 2026, from 11:30 AM to 12:45 PM PST, enhancing Tyra's academic influence in the oncology field.
- Future Development Directions: Dabogratinib, as a potential first-in-class selective FGFR3 inhibitor, is undergoing multiple clinical studies, showcasing Tyra's robust R&D capabilities and market potential in precision medicine.
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Analyst Views on TYRA
Wall Street analysts forecast TYRA stock price to rise
5 Analyst Rating
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 31.580
Low
30.00
Averages
33.75
High
37.00
Current: 31.580
Low
30.00
Averages
33.75
High
37.00
About TYRA
Tyra Biosciences, Inc. is a clinical-stage biotechnology company focused on developing precision medicines that target large opportunities in FGFR biology. Its in-house precision medicine platform, SNAP, enables precise drug design through iterative molecular SNAPshots that help predict genetic alterations to cause acquired resistance to existing therapies. It has a differentiated pipeline with three product candidates in clinical development in targeted oncology and genetically defined conditions. Its lead precision medicine stemming from SNAP, TYRA-300, is a potential selective FGFR3 inhibitor that is designed to avoid the toxicities associated with inhibition of FGFR1, FGFR2 and FGFR4, while being agnostic for the FGFR3 gatekeeper mutations. It is also developing TYRA-200, an oral, investigational, FGFR1/2/3 inhibitor, in the SURF201 study for metastatic intrahepatic cholangiocarcinoma, and TYRA-430, an oral, investigational FGFR4/3-biased inhibitor for FGF19+/FGFR4-driven cancers.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Tyra Biosciences Presents Two Abstracts at ASCO GU Symposium
- Abstract Presentation: Tyra Biosciences announced the acceptance of two abstracts for the 2026 ASCO GU Symposium, focusing on research related to FGFR3-altered metastatic urothelial cancer and low-grade non-muscle invasive bladder cancer, highlighting the company's advancements in FGFR biology.
- Clinical Trial Details: The first abstract pertains to the SURF301 trial, which monitors ctDNA in patients treated with dabogratinib for FGFR3-altered metastatic urothelial cancer, while the second focuses on the SURF302 trial evaluating the efficacy and safety of dabogratinib in low-grade non-muscle invasive bladder cancer patients.
- Conference Schedule: Both studies will be presented during the poster session on February 27, 2026, from 11:30 AM to 12:45 PM PST, enhancing Tyra's academic influence in the oncology field.
- Future Development Directions: Dabogratinib, as a potential first-in-class selective FGFR3 inhibitor, is undergoing multiple clinical studies, showcasing Tyra's robust R&D capabilities and market potential in precision medicine.
See More
Tyra Biosciences to Present New Research at ASCO GU Conference
- Research Presentation: Tyra Biosciences announced that two abstracts have been accepted for the 2026 ASCO GU Cancer Symposium, showcasing its latest advancements in FGFR biology, which is expected to enhance the company's reputation in precision medicine.
- Clinical Trial Progress: One study involves ctDNA monitoring of FGFR3-altered metastatic urothelial cancer patients treated with dabogratinib (formerly TYRA-300), demonstrating the company's innovative capabilities in cancer treatment.
- Multicenter Study: The other study is a Phase 2 multicenter, open-label trial evaluating the efficacy and safety of dabogratinib in participants with FGFR3-altered low-grade, intermediate-risk non-muscle invasive bladder cancer, further solidifying TYRA's clinical standing in oncology.
- Future Development Potential: TYRA's oral dabogratinib, a potential first-in-class selective FGFR3 inhibitor, is undergoing multiple Phase 2 clinical studies, indicating the company's broad application prospects in FGFR-targeted therapies.
See More
Healthcare Stocks Surge in After-Hours Trading
- Acumen Pharmaceuticals Surge: Acumen Pharmaceuticals, Inc. (ABOS) advanced 8.09% in after-hours trading to close at $2.94, adding $0.22, indicating strong investor confidence in its growth prospects.
- Fulgent Genetics Rise: Fulgent Genetics, Inc. (FLGT) rose 5.98% to $28.90 in after-hours trading, gaining $1.63, reflecting market optimism regarding its business outlook.
- Fractyl Health Growth: Fractyl Health, Inc. (GUTS) climbed 5.19% to $2.23 after hours, up $0.11, suggesting that its potential in the biotech sector is being recognized by the market.
- Coeptis Therapeutics Increase: Coeptis Therapeutics Holdings, Inc. (COEP) added 4.14% to finish at $13.85, gaining $0.55 in after-hours trading, demonstrating investor support for its strategic direction.
See More
Tyra Biosciences Director Sells 246,871 Shares for $5 Million
- Insider Transaction: On November 21, Tyra Biosciences Director Robert J. More sold 246,871 shares at $20.25 each for a total of $5 million, indicating confidence in the company's future despite being part of a Rule 10b5-1 trading plan.
- Shareholding Status: Post-transaction, More retains 3,833,425 shares valued at approximately $77.6 million at current prices, reflecting his ongoing belief in the company's long-term prospects.
- Market Performance: As of December 23, Tyra's stock has surged over 80% year-to-date, significantly outperforming the S&P 500's 18.4% return, indicating strong market optimism regarding its growth potential.
- Financial Condition: Although the third-quarter report showed slight increases in R&D and SG&A expenses along with a higher net loss, analysts generally rate Tyra as a moderate buy, suggesting confidence in its future growth despite its early-stage status.
See More
Tyra Biosciences Director Sells 246,871 Shares, Retains $77.6 Million Stake
- Share Sale: On November 21, 2025, Tyra Biosciences Director Robert More sold 246,871 shares under a Rule 10b5-1 trading plan at $20.25 per share, yet retains nearly 4 million shares valued at approximately $77.6 million, indicating continued confidence in the company's prospects.
- Stock Performance: As of December 23, 2025, Tyra's stock has surged over 80% year-to-date, significantly outperforming the S&P 500's 18.4% return, reflecting optimistic market sentiment regarding its biotechnology potential.
- Financial Status: In its early November Q3 earnings report, Tyra disclosed slight increases in R&D and SG&A expenses along with a higher net loss, despite not generating any revenue, highlighting the inherent risks of its early-stage operations.
- Management Changes: The company announced in December the appointments of Bhavesh Ashar as Chief Operating Officer and Heather Faulds as Chief Regulatory Officer, aiming to strengthen its management team to support future business growth and strategic execution.
See More
Accenture Set to Surge Over 16%? Check Out 10 Leading Analyst Predictions for Tuesday
Analyst Upgrades: Morgan Stanley upgraded Accenture Plc from Equal-Weight to Overweight, raising its price target from $271 to $320, while Cantor Fitzgerald upgraded Microchip Technology Inc from Neutral to Overweight with a target increase from $65 to $85.
Price Target Increases: Wedbush raised Tyra Biosciences Inc's target from $30 to $37, and Chardan Capital increased Palvella Therapeutics Inc's target from $110 to $174, both maintaining positive ratings.
Mixed Ratings: Baird cut Dentsply Sirona Inc's price target from $14 to $12 while maintaining a Neutral rating, contrasting with their upgrade of Tandem Diabetes Care Inc from Neutral to Outperform with a target increase from $18 to $30.
Other Notable Changes: Goldman Sachs upgraded Rockwell Automation Inc from Sell to Neutral, raising its target from $329 to $448, while Needham increased SI-Bone Inc's target from $24 to $27, maintaining a Buy rating.
See More
Tyra Biosciences Presents Two Abstracts at ASCO GU Symposium
- Abstract Presentation: Tyra Biosciences announced the acceptance of two abstracts for the 2026 ASCO GU Symposium, focusing on research related to FGFR3-altered metastatic urothelial cancer and low-grade non-muscle invasive bladder cancer, highlighting the company's advancements in FGFR biology.
- Clinical Trial Details: The first abstract pertains to the SURF301 trial, which monitors ctDNA in patients treated with dabogratinib for FGFR3-altered metastatic urothelial cancer, while the second focuses on the SURF302 trial evaluating the efficacy and safety of dabogratinib in low-grade non-muscle invasive bladder cancer patients.
- Conference Schedule: Both studies will be presented during the poster session on February 27, 2026, from 11:30 AM to 12:45 PM PST, enhancing Tyra's academic influence in the oncology field.
- Future Development Directions: Dabogratinib, as a potential first-in-class selective FGFR3 inhibitor, is undergoing multiple clinical studies, showcasing Tyra's robust R&D capabilities and market potential in precision medicine.
See More
Tyra Biosciences to Present New Research at ASCO GU Conference
- Research Presentation: Tyra Biosciences announced that two abstracts have been accepted for the 2026 ASCO GU Cancer Symposium, showcasing its latest advancements in FGFR biology, which is expected to enhance the company's reputation in precision medicine.
- Clinical Trial Progress: One study involves ctDNA monitoring of FGFR3-altered metastatic urothelial cancer patients treated with dabogratinib (formerly TYRA-300), demonstrating the company's innovative capabilities in cancer treatment.
- Multicenter Study: The other study is a Phase 2 multicenter, open-label trial evaluating the efficacy and safety of dabogratinib in participants with FGFR3-altered low-grade, intermediate-risk non-muscle invasive bladder cancer, further solidifying TYRA's clinical standing in oncology.
- Future Development Potential: TYRA's oral dabogratinib, a potential first-in-class selective FGFR3 inhibitor, is undergoing multiple Phase 2 clinical studies, indicating the company's broad application prospects in FGFR-targeted therapies.
See More
Healthcare Stocks Surge in After-Hours Trading
- Acumen Pharmaceuticals Surge: Acumen Pharmaceuticals, Inc. (ABOS) advanced 8.09% in after-hours trading to close at $2.94, adding $0.22, indicating strong investor confidence in its growth prospects.
- Fulgent Genetics Rise: Fulgent Genetics, Inc. (FLGT) rose 5.98% to $28.90 in after-hours trading, gaining $1.63, reflecting market optimism regarding its business outlook.
- Fractyl Health Growth: Fractyl Health, Inc. (GUTS) climbed 5.19% to $2.23 after hours, up $0.11, suggesting that its potential in the biotech sector is being recognized by the market.
- Coeptis Therapeutics Increase: Coeptis Therapeutics Holdings, Inc. (COEP) added 4.14% to finish at $13.85, gaining $0.55 in after-hours trading, demonstrating investor support for its strategic direction.
See More
Tyra Biosciences Director Sells 246,871 Shares for $5 Million
- Insider Transaction: On November 21, Tyra Biosciences Director Robert J. More sold 246,871 shares at $20.25 each for a total of $5 million, indicating confidence in the company's future despite being part of a Rule 10b5-1 trading plan.
- Shareholding Status: Post-transaction, More retains 3,833,425 shares valued at approximately $77.6 million at current prices, reflecting his ongoing belief in the company's long-term prospects.
- Market Performance: As of December 23, Tyra's stock has surged over 80% year-to-date, significantly outperforming the S&P 500's 18.4% return, indicating strong market optimism regarding its growth potential.
- Financial Condition: Although the third-quarter report showed slight increases in R&D and SG&A expenses along with a higher net loss, analysts generally rate Tyra as a moderate buy, suggesting confidence in its future growth despite its early-stage status.
See More
Tyra Biosciences Director Sells 246,871 Shares, Retains $77.6 Million Stake
- Share Sale: On November 21, 2025, Tyra Biosciences Director Robert More sold 246,871 shares under a Rule 10b5-1 trading plan at $20.25 per share, yet retains nearly 4 million shares valued at approximately $77.6 million, indicating continued confidence in the company's prospects.
- Stock Performance: As of December 23, 2025, Tyra's stock has surged over 80% year-to-date, significantly outperforming the S&P 500's 18.4% return, reflecting optimistic market sentiment regarding its biotechnology potential.
- Financial Status: In its early November Q3 earnings report, Tyra disclosed slight increases in R&D and SG&A expenses along with a higher net loss, despite not generating any revenue, highlighting the inherent risks of its early-stage operations.
- Management Changes: The company announced in December the appointments of Bhavesh Ashar as Chief Operating Officer and Heather Faulds as Chief Regulatory Officer, aiming to strengthen its management team to support future business growth and strategic execution.
See More
Accenture Set to Surge Over 16%? Check Out 10 Leading Analyst Predictions for Tuesday
Analyst Upgrades: Morgan Stanley upgraded Accenture Plc from Equal-Weight to Overweight, raising its price target from $271 to $320, while Cantor Fitzgerald upgraded Microchip Technology Inc from Neutral to Overweight with a target increase from $65 to $85.
Price Target Increases: Wedbush raised Tyra Biosciences Inc's target from $30 to $37, and Chardan Capital increased Palvella Therapeutics Inc's target from $110 to $174, both maintaining positive ratings.
Mixed Ratings: Baird cut Dentsply Sirona Inc's price target from $14 to $12 while maintaining a Neutral rating, contrasting with their upgrade of Tandem Diabetes Care Inc from Neutral to Outperform with a target increase from $18 to $30.
Other Notable Changes: Goldman Sachs upgraded Rockwell Automation Inc from Sell to Neutral, raising its target from $329 to $448, while Needham increased SI-Bone Inc's target from $24 to $27, maintaining a Buy rating.
See More
