TScan Therapeutics Set to Update on Phase 1 Trial of TSC-101 for Hematologic Cancers Next Week
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 04 2025
0mins
Source: NASDAQ.COM
KOL Event Announcement: TScan Therapeutics Inc. will host a virtual key opinion leader event on December 8, 2025, to discuss updates from its ALLOHA trial, which evaluates TSC-101 in patients with hematologic malignancies undergoing allogeneic hematopoietic cell transplantation.
TSC-101 Therapy Details: TSC-101 is an allogeneic T-cell therapy targeting minor histocompatibility antigens, showing a favorable safety profile and significant relapse-free benefit, with 82% of treated patients remaining relapse-free compared to 64% in the control group.
Regulatory Progress: Following a successful End-of-Phase 1 meeting with the FDA, TScan has established a registrational path for TSC-101 as a treatment for acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).
Future Trials: A pivotal trial for TSC-101 targeting AML and MDS patients is anticipated to begin in the second quarter of 2026, with TCRX's stock closing at $1.02, reflecting a 7.12% increase.
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Analyst Views on TCRX
Wall Street analysts forecast TCRX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for TCRX is 5.50 USD with a low forecast of 3.00 USD and a high forecast of 7.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
7 Analyst Rating
5 Buy
2 Hold
0 Sell
Moderate Buy
Current: 1.040
Low
3.00
Averages
5.50
High
7.00
Current: 1.040
Low
3.00
Averages
5.50
High
7.00
About TCRX
TScan Therapeutics, Inc. is a clinical-stage biotechnology company. The Company is focused on developing a robust pipeline of T cell receptor (TCR)-engineered T cell (TCR-T) therapies for the treatment of patients with cancer. The Company’s lead TCR-T therapy candidates, TSC-100 and TSC-101, are in development for the treatment of patients with hematologic malignancies to prevent relapse following allogeneic hematopoietic cell transplantation. The Company is also developing multiple TCR-T therapy product candidates for the treatment of solid tumors. The Company has developed and continues to build its ImmunoBank with TCRs across different targets and human leukocyte antigens types to enable customized multiplex TCR-T therapy. Its solid tumors programs include TSC-200, TSC-201, TSC-202, TSC-203, and TSC-204. Its hematologic malignancies programs include TSC-100, TSC-101, and TSC-102.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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GT Biopharma Advances GTB-3650 Clinical Trial to Cohort 4 with 10μg/kg/day Dosing
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