Nutex Health Rises 21% in After-Hours Trading Following Revenue Increase; Biotech Competitors Also See Gains on Tuesday
Nutex Health's Performance: Nutex Health Inc. saw a significant after-hours surge of 20.97% to $120.00 following a quarterly report that revealed a net loss of $17.7 million but a remarkable 220.7% increase in revenue year-over-year to $244.0 million.
Bullfrog AI Holdings Update: Bullfrog AI Holdings, Inc. gained 5.87% to $0.9798 in after-hours trading, likely due to investor positioning ahead of its upcoming technical presentation at the AI Drug Discovery & Development Summit 2025.
Clearside Biomedical's Recovery: Clearside Biomedical, Inc. rose 6.51% to $3.27 after reporting a narrower net loss of $5.97 million, although its revenue fell sharply to $201 thousand from $1.04 million a year ago.
Aytu BioPharma and OKYO Pharma Developments: Aytu BioPharma, Inc. climbed 8.91% to $2.20 after reporting a first-quarter net income increase, while OKYO Pharma Limited edged up 2.44% to $2.18, preparing for a presentation on its investigational drug candidate for neuropathic corneal pain.
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Johnson & Johnson Reports Positive Phase 2b Results for Lupus Drug Nipocalimab, Plans Phase 3 Trial
- Positive Study Results: Johnson & Johnson's JASMINE study involving 228 systemic lupus erythematosus patients met its primary endpoint, demonstrating statistically significant improvement in patient response rates at Week 24 compared to placebo, marking the first positive results for an investigational FcRn blocker in this indication.
- Safety Profile Consistent: Nipocalimab exhibited a safety and tolerability profile consistent with previous Phase 2 studies, with no new safety signals identified, thereby establishing a solid foundation for further clinical development.
- Significant Market Potential: With systemic lupus erythematosus affecting an estimated 3 to 5 million people globally, including 450,000 in the U.S., the positive study results could provide a strong competitive advantage for Johnson & Johnson in this market.
- Clear Next Steps: Following the positive Phase 2 results, Johnson & Johnson plans to initiate a Phase 3 program for Nipocalimab, aiming to further validate its therapeutic potential in systemic lupus erythematosus, which could drive future revenue growth for the company.

Adicet Bio Announces 1-for-16 Reverse Stock Split to Maintain Listing Compliance
- Reverse Stock Split Plan: Adicet Bio announced a 1-for-16 reverse stock split effective December 30, which will reduce the outstanding shares from approximately 153.3 million to about 9.6 million, enabling the company to regain compliance with the minimum bid price requirement for continued listing.
- Shareholder Approval: The plan was approved by shareholders at a special meeting last week, indicating support for the company's governance and future direction, although this move may lead to short-term stock price volatility.
- Stock Price Impact: Following the announcement, Adicet Bio shares fell by 5.78%, trading at $0.49, reflecting market caution regarding the measure and potentially impacting investor confidence.
- Incentive Plan Adjustments: Proportional adjustments will be made to shares included in the company's equity incentive plans, with no fractional shares issued, aimed at maintaining the effectiveness of employee incentives while ensuring stability in the company's capital structure.









