Novartis Announces Positive Phase III Results for Oral Remibrutinib
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1 day ago
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Should l Buy NVS?
Novartis announced topline results from its Phase III RemIND trial of oral remibrutinib in chronic inducible urticaria, ClndU. The primary endpoint was met for the three most prevalent types of CIndU: symptomatic dermographism, cold urticaria and cholinergic urticaria, achieving significantly higher complete response rates versus placebo at Week 121. These data represent an important advance in the treatment of CIndU, demonstrating the potential of remibrutinib to be the first targeted therapy for CIndU and address a major unmet need. "The positive RemIND trial results across three different types of CIndU underscore the potential of oral remibrutinib to achieve complete symptom relief for people living with CIndU and build on its recent FDA approval in chronic spontaneous urticaria," said Angelika Jahreis, Global Head, Immunology Development, Novartis. "Today's findings reinforce that remibrutinib could be the first targeted therapy to improve spontaneous and inducible forms of chronic urticaria, helping address a major gap in care for people living with these conditions."
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Analyst Views on NVS
Wall Street analysts forecast NVS stock price to fall
6 Analyst Rating
1 Buy
4 Hold
1 Sell
Hold
Current: 165.380
Low
112.00
Averages
127.75
High
143.00
Current: 165.380
Low
112.00
Averages
127.75
High
143.00
About NVS
Novartis AG is a Switzerland-based pharmaceutical company. The Company develops, manufactures, and markets branded and generic prescription drugs, active pharmaceutical ingredients (APIs), biosimilars and ophthalmic products. The Company uses science and digital technologies for treatments in the disease areas of immunology, dermatology, cancer, ophthalmology, neuroscience, respiratory, cardiovascular, renal and metabolism. The business activities of the Company are divided into two segments: Innovative Medicines, which includes innovative patent-protected prescription medicines for blood pressure, cancer and other ailments, and Sandoz, which includes generic pharmaceuticals and biosimilars.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Complementary Expertise: This partnership leverages Unnatural Products' AI-enhanced macrocycle platform alongside Novartis' global expertise in drug development and commercialization, which is expected to accelerate the development of new therapies.
- Clinical Development Responsibility: Novartis will lead the clinical trials, production, and commercialization of the products, while Unnatural Products will receive up to $100 million in upfront and pre-IND milestone payments, ensuring liquidity during the project's early stages.
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- First Targeted Therapy: The data signifies remibrutinib's potential as the first targeted therapy for CIndU, with Global Head of Immunology Development Angelika Jahreis highlighting its positive trial results as a foundation for recent FDA approval in chronic spontaneous urticaria.
- Regulatory Progress: Novartis has submitted a supplemental New Drug Application (sNDA) to the U.S. FDA for remibrutinib's approval in symptomatic dermographism, enhancing its market position in urticaria treatment.
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- Increased Investor Attention: With ongoing innovations and policy support in the health care industry, investor attention towards health care stocks has significantly increased, potentially attracting more capital into the sector and driving stock prices higher.
- Optimistic Industry Outlook: The growth potential and stability of the health care sector make it attractive amid economic uncertainties, leading investors to view it as a safe haven, further propelling the upward trend in health care stocks.
See More
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