Nektar (NKTR) Q4 2025 Earnings Call Transcript
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1 hour ago
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Should l Buy NKTR?
Source: NASDAQ.COM
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Analyst Views on NKTR
Wall Street analysts forecast NKTR stock price to rise
8 Analyst Rating
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 73.330
Low
102.00
Averages
123.43
High
165.00
Current: 73.330
Low
102.00
Averages
123.43
High
165.00
About NKTR
Nektar Therapeutics is a clinical-stage biotechnology company. It is focused on developing treatments that address the underlying immunological dysfunction in autoimmune and chronic inflammatory diseases. In oncology, it is focused on developing medicines based on targeting biological pathways that stimulate and sustain the body’s immune response to fight cancer. Its lead product candidate, rezpegaldesleukin (REZPEG, or NKTR-358), is a novel regulatory T cell stimulator being evaluated in two Phase IIb clinical trials, one in atopic dermatitis and one in alopecia areata. Its pipeline also includes a preclinical bivalent tumor necrosis factor receptor type II (TNFR2) antibody and bispecific programs, NKTR-0165 and NKTR-0166, and a modified hematopoietic colony stimulating factor (CSF) protein, NKTR-422. It is also evaluating NKTR-255, an investigational IL-15 receptor agonist designed to boost the immune system's natural ability to fight cancer, in several ongoing clinical trials.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Earnings Announcement Schedule: Nektar Therapeutics is set to announce its Q4 earnings on March 12 after market close, with consensus EPS estimate at -$2.47 and revenue estimate at $10.41 million, reflecting a significant 64.3% year-over-year decline, indicating substantial revenue pressure on the company.
- Historical Performance Review: Over the past two years, Nektar has only beaten EPS estimates 38% of the time and revenue estimates 63% of the time, highlighting considerable volatility in its performance and suggesting that investors should approach future results with caution.
- Estimate Revision Status: In the last three months, there have been no upward revisions to EPS estimates and one downward revision, with revenue estimates also seeing no upward revisions and one downward revision, indicating a lack of confidence in the company's future profitability.
- Financing Activities: Nektar recently completed a $400 million stock offering, and its stock surged following a $300 million equity offering, reflecting a positive market response to its financing activities, although its overall financial health remains a concern.
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- Legal Investigation Launched: Faruq & Faruqi LLP is investigating potential claims against Nektar Therapeutics, focusing on investors who purchased securities between February 26, 2025, and December 15, 2025, indicating a commitment to protecting investor rights.
- Investor Contact Information: The firm encourages affected investors to contact partner Josh Wilson directly at 877-247-4292 or 212-983-9330 (Ext. 1310) to discuss their legal options, demonstrating their dedication to supporting investors.
- Class Action Deadline: Faruq & Faruqi reminds investors that the deadline to seek lead plaintiff status in the federal securities class action against Nektar is May 5, 2026, highlighting the importance of timely action to safeguard legal rights.
- Role of Securities Law Firm: As a leading national securities law firm, the investigation by Faruq & Faruqi suggests that Nektar may face legal challenges, which could impact its stock price and market confidence, prompting investors to stay alert for further developments.
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- Lawsuit Background: Robbins LLP reminds all investors who purchased Nektar Therapeutics (NASDAQ: NKTR) securities between February 26, 2025, and December 15, 2025, that a class action has been filed, alleging the company failed to disclose the true prospects of the REZOLVE-AA trial, potentially leading to investor losses.
- Trial Issues: The complaint states that Nektar did not follow applicable instructions and protocol standards in the REZOLVE-AA trial, resulting in an overstated integrity and prospects of the trial, which undermines investor confidence in the company's future.
- Stock Price Impact: On December 16, 2025, Nektar announced that the REZOLVE-AA trial failed to achieve statistical significance, causing its stock price to drop by $4.14, or 7.77%, closing at $49.16 per share, reflecting market disappointment in the company's outlook.
- Investor Action: Robbins LLP encourages shareholders to participate in the class action, where lead plaintiffs can represent other members in the litigation, and investors do not need to participate in the case to be eligible for recovery, highlighting potential governance issues within the company.
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- Class Action Initiated: A shareholder has filed a class action lawsuit on behalf of investors who purchased Nektar Therapeutics (NASDAQ: NKTR) securities between February 26, 2025, and December 15, 2025, alleging misrepresentations regarding the Phase 2b trial for REZOLVE-AA, which may have led to investor losses.
- Lawsuit Details Revealed: The lawsuit, initiated by Bernstein Liebhard LLP, requires investors wishing to serve as lead plaintiffs to file necessary documents by May 5, 2026, indicating their representative status in the litigation.
- Law Firm Background: Bernstein Liebhard LLP has recovered over $3.5 billion for clients since 1993 and has been recognized multiple times in The National Law Journal’s “Plaintiffs’ Hot List” for its success in handling hundreds of class actions, showcasing its significant influence in the legal field.
- Transparent Fee Structure: All representation in this lawsuit is on a contingency fee basis, meaning shareholders incur no fees or expenses, ensuring minimal financial burden for all investors participating in the litigation.
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- Class Action Initiation: Rosen Law Firm has filed a class action lawsuit on behalf of investors who purchased Nektar Therapeutics securities between February 26, 2025, and December 15, 2025, indicating potential misleading statements that could undermine investor confidence.
- Compensation Structure: Investors may receive compensation without any out-of-pocket costs through a contingency fee arrangement, suggesting a risk-free remedy for affected investors and potentially increasing participation in the lawsuit.
- Details of Allegations: The lawsuit claims that Nektar failed to adhere to applicable standards in the REZOLVE-AA trial, raising concerns about the integrity of the trial results, which could negatively impact the company's future prospects and market performance.
- Law Firm Credentials: Rosen Law Firm is recognized for its successful track record in securities class actions, having recovered over $438 million for investors in 2019 alone, demonstrating its expertise and influence in handling such cases.
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