IN8bio Appoints Kate Rochlin as President and COO
- Executive Appointment: IN8bio has announced the immediate promotion of Dr. Kate Rochlin to President and Chief Operating Officer, having previously served as COO since December 2021, overseeing company operations and advancing clinical and preclinical pipelines, marking a strategic focus on growth.
- Leadership Enhancement: Dr. Rochlin has been instrumental in advancing IN8bio's clinical programs and T cell engager platform, with her leadership aligning teams across operations, manufacturing, clinical, and research, ensuring critical milestones are met on schedule, thereby enhancing the company's execution capabilities.
- Clinical Progress: Under her leadership, IN8bio's INB-619 project has made significant strides, with preclinical data showing that it achieved complete B cell depletion comparable to approved T cell engagers with minimal adverse effects, highlighting the company's competitive edge in the field of autoimmune diseases.
- Manufacturing Capability Expansion: Dr. Rochlin has also played a key role in developing and expanding IN8bio's clinical manufacturing program, leading analytical, quality, regulatory, and GMP manufacturing teams across multiple Phase 1 and 2 clinical programs in glioblastoma and hematological cancers, ensuring the company's sustained growth in these areas.
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- Executive Appointment: IN8bio has promoted Kate Rochlin to president and chief operating officer, effective immediately, recognizing her leadership since serving as COO since December 2021, which reflects the company's confidence in her capabilities.
- Funding Initiative: IN8bio plans to raise up to $40.2 million through an at-the-market private placement, aimed at strengthening its capital structure and providing financial support for future R&D and operations, thereby driving growth in the biopharmaceutical sector.
- Historical Performance Review: Historical financial data for IN8bio indicates robust revenue growth over the past fiscal year, showcasing the company's competitiveness and the sustained demand in the biopharmaceutical market.
- Quant Rating Insight: Seeking Alpha's Quant Rating on IN8bio reveals a positive market outlook for its future performance, potentially attracting more investor interest and enhancing the company's stock price performance.
- Executive Appointment: IN8bio has announced the immediate promotion of Dr. Kate Rochlin to President and Chief Operating Officer, having previously served as COO since December 2021, overseeing company operations and advancing clinical and preclinical pipelines, marking a strategic focus on growth.
- Leadership Enhancement: Dr. Rochlin has been instrumental in advancing IN8bio's clinical programs and T cell engager platform, with her leadership aligning teams across operations, manufacturing, clinical, and research, ensuring critical milestones are met on schedule, thereby enhancing the company's execution capabilities.
- Clinical Progress: Under her leadership, IN8bio's INB-619 project has made significant strides, with preclinical data showing that it achieved complete B cell depletion comparable to approved T cell engagers with minimal adverse effects, highlighting the company's competitive edge in the field of autoimmune diseases.
- Manufacturing Capability Expansion: Dr. Rochlin has also played a key role in developing and expanding IN8bio's clinical manufacturing program, leading analytical, quality, regulatory, and GMP manufacturing teams across multiple Phase 1 and 2 clinical programs in glioblastoma and hematological cancers, ensuring the company's sustained growth in these areas.
Securities Purchase Agreement: IN8bio, Inc. has finalized a securities purchase agreement to raise approximately $40.2 million through a private placement involving new and existing institutional investors, as well as company directors and officers.
Funding Allocation: The funds from the initial closing, estimated at $20.1 million, will support operations until mid-2027 and facilitate IND-enabling studies for INB-619, along with regulatory efforts for glioblastoma programs INB-200 and INB-400.
Current Stock Performance: INAB's stock is currently trading at $1.36, reflecting a decrease of $0.02 or 1.45 percent on the Nasdaq.
Disclaimer: The views expressed in the article are those of the author and do not necessarily represent the opinions of Nasdaq, Inc.
- Financing Amount: IN8bio has secured up to $40.2 million through a securities purchase agreement with institutional investors, with an initial $20.1 million aimed at advancing the IND application for INB-619, ensuring operational funding through the first half of 2027.
- Investor Participation: The financing is led by Coastlands Capital and includes participation from both new and existing investors such as Stonepine Capital Management and 683 Capital Partners, reflecting strong market confidence in IN8bio's innovative therapies.
- Equity Structure: The initial tranche involves the sale of 5,127,029 shares at $1.38 per share, along with pre-funded warrants, enhancing the company's capital flexibility and competitive positioning in the biopharmaceutical market.
- Clinical Research Plans: IN8bio intends to use the proceeds to fund IND enabling studies for INB-619, with expectations to engage with the FDA in 2026 and submit pivotal animal model data in 2027, thereby advancing the product's path to market.
- Financing Agreement: IN8bio has entered into a securities purchase agreement with institutional investors for an initial $20.1 million, expected to extend its cash runway into the first half of 2027, ensuring operational stability during clinical development.
- Follow-on Financing Potential: The agreement includes an additional $20.1 million in milestone-driven financing, which will enhance the company's research capabilities in oncology and autoimmune diseases if preclinical data for INB-619 meets specified criteria.
- Equity Structure Optimization: The financing will issue 5,127,029 shares of common stock at $1.38 per share, along with pre-funded warrants for 9,452,677 shares, enhancing investor engagement and the company's capital flexibility.
- FDA Interaction Plan: IN8bio plans to engage with the FDA in 2026 for initial discussions, with an IND submission anticipated in 2027, aimed at accelerating the clinical development of INB-619 and improving market competitiveness.

Private Placement Agreement: IN8bio has entered into a definitive securities purchase agreement for a private placement aiming to raise approximately $40.2 million, with an initial tranche expected to generate about $20.1 million.
Share Sale Details: The company plans to sell 5.13 million shares at $1.38 each and pre-funded warrants for up to 9.45 million shares at the same price, with the initial closing anticipated around December 22, 2025.
Use of Proceeds: Funds raised will support IND-enabling studies for INB-619, advancement of glioblastoma programs INB-200 and INB-400, FDA interactions, and general corporate purposes.
Market Reaction: Following the announcement, IN8bio's shares experienced a 5% increase in premarket trading.










