Heron Therapeutics (HRTX) Reports Q2 Loss, Misses Revenue Estimates
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Aug 08 2025
0mins
Should l Buy HRTX?
Source: NASDAQ.COM
Heron Therapeutics Earnings Report: Heron Therapeutics reported a quarterly loss of $0.02 per share, missing the Zacks Consensus Estimate of a loss of $0.01, while revenues of $37.2 million also fell short of expectations. The company's stock has gained approximately 20.3% this year, outperforming the S&P 500.
Future Outlook and Industry Context: The earnings outlook for Heron Therapeutics remains mixed, with a current Zacks Rank of #3 (Hold), indicating expected performance in line with the market. The Medical - Drugs industry is ranked in the top 32% of Zacks industries, suggesting potential positive impacts on stock performance.
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Analyst Views on HRTX
Wall Street analysts forecast HRTX stock price to rise
4 Analyst Rating
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 1.240
Low
3.00
Averages
4.50
High
6.00
Current: 1.240
Low
3.00
Averages
4.50
High
6.00
About HRTX
Heron Therapeutics, Inc. is a commercial-stage biotechnology company focused on improving the lives of patients by developing and commercializing therapeutics that improve medical care. Its acute care product portfolio includes ZYNRELEF, APONVIE, CINVANTI, and SUSTOL. ZYNRELEF is a dual-acting local anesthetic that delivers a fixed-dose combination of the local anesthetic bupivacaine and a low-dose of the nonsteroidal anti-inflammatory drug meloxicam. APONVIE is the intravenous formulation of aprepitant, a substance P/neurokinin-1 receptor antagonist indicated for postoperative nausea and vomiting in adults. CINVANTI is an IV formulation of aprepitant, a substance NK1 receptor antagonist. SUSTOL is the first extended-release 5-HT3 receptor antagonist approved for the prevention of acute and delayed nausea and vomiting associated with both MEC and anthracycline and cyclophosphamide combination chemotherapy regimens.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Earnings Announcement: Heron Therapeutics (HRTX) is set to release its Q1 2023 earnings report on May 11 before market open, with consensus EPS estimate at -$0.03 and revenue estimate at $36.72 million, reflecting a 5.6% year-over-year decline.
- Performance Expectations: Over the past year, HRTX has beaten EPS estimates 50% of the time and revenue estimates 75% of the time, indicating a potential for continued improvement in profitability and revenue growth.
- Sales Target Outlook: The company has outlined ambitious sales targets for 2026, ranging from $173 million to $183 million, driven by momentum in acute care and expanded commercial investments, showcasing strategic growth initiatives.
- Market Performance Assessment: Despite mixed results in Q4, Heron Therapeutics is actively promoting its FY26 outlook, suggesting that its current position at the bottom of a trading range may present potential buying opportunities for investors.
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- Conference Call Announcement: Heron Therapeutics will host a conference call on May 11, 2026, at 8:30 a.m. ET to report its Q1 2026 financial results and discuss recent business highlights, aiming to provide transparent communication with investors.
- Participation Details: Participants can access the call via a registration link for dial-in details, and are encouraged to join 15 minutes early to avoid delays, reflecting the company's commitment to investor relations.
- Webcast Availability: The conference call will also be available via webcast on Heron's Investor Relations section of its website, with an archive of the teleconference and webcast accessible for 60 days post-call, allowing investors who cannot attend live to catch up.
- Company Overview: Heron Therapeutics is a commercial-stage biotechnology company focused on improving patient lives through therapeutic innovations, leveraging advanced science and patented technologies to develop a portfolio aimed at enhancing the standard of care for acute and oncology patients.
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- Successful Financing Completion: CEO Craig Collard emphasized the successful completion of financing, describing it as a 'meaningful derisking event' that allows the company to focus on commercial execution and product expansion, thereby driving sustained growth.
- Strong Financial Performance: Full-year net revenues for 2025 reached approximately $155 million, with adjusted EBITDA of $14.7 million, exceeding prior guidance of $9 million to $13 million, showcasing the company's financial robustness and growth potential.
- Acute Care Product Line Growth: ZYNRELEF achieved a 48% net revenue growth in Q4, while APONVIE grew by 97%, leading to an overall year-over-year increase of over 57% in the Acute Care franchise, indicating the company's strengthening competitive position in the market.
- Optimistic 2026 Outlook: Management raised the 2026 net product sales guidance to $173 million to $183 million, with expectations of EBITDA positivity, reflecting confidence in commercial expansion and the strategic necessity of targeted investments.
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- Earnings Performance: Heron Therapeutics reported a Q4 GAAP EPS of -$0.02, missing estimates by $0.01, although revenue reached $40.59 million, a slight 0.5% year-over-year decline, yet exceeding market expectations by $1.06 million, indicating some effectiveness in revenue management.
- Acute Care Growth: The Acute Care franchise achieved a remarkable 57.3% year-over-year revenue growth in Q4 2025 and 65.1% for the full year compared to 2024, suggesting strong market demand in this segment, potentially laying the groundwork for sustained future growth.
- Cash Position: As of December 31, 2025, Heron reported cash, cash equivalents, and short-term investments totaling $46.6 million, reflecting robust liquidity management that supports future operations and investments.
- 2026 Financial Guidance: Heron provided a 2026 net revenue guidance of $173 to $183 million and an adjusted EBITDA forecast of $10 to $20 million, both exceeding the consensus estimate of $171.73 million, demonstrating the company's confidence in its future performance.
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- Earnings Announcement Date: Heron Therapeutics (HRTX) is set to announce its Q4 2023 earnings on February 26 before the market opens, drawing significant attention from investors regarding its performance.
- Earnings Expectations: The consensus EPS estimate stands at -$0.03, indicating potential profitability challenges that could affect investor confidence in the company's financial health.
- Revenue Projections: The revenue estimate is $39.53 million, reflecting a 3.1% year-over-year decline, which suggests that the company is facing challenges in a competitive market environment that may impact future growth prospects.
- Historical Performance Review: Over the past year, HRTX has beaten EPS estimates 50% of the time and revenue estimates 75% of the time, indicating that the company has a track record of exceeding expectations to some extent.
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