Evolus Enters Exclusive Agreement with IBSA to Develop Profhilo
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 8 hours ago
0mins
Evolus has entered into an exclusive licensing and distribution agreement with IBSA, a Swiss multinational pharmaceutical company, to develop and commercialize Profhilo in the U.S. Profhilo is an injectable for skin quality, with more than 4.8 million treatments administered worldwide since its launch in 2015. Profhilo features a unique hyaluronic acid formulation intended for superficial application to improve overall skin quality, including hydration, elasticity, and smoothness. Evolus will be responsible for development activities required for U.S. regulatory approval, as well as commercialization of the product following approval. The economics are structured through a transfer-price model designed to support gross margins consistent with Evolus' long-term financial framework. The agreement is not expected to impact the company's 2026 revenue, operating expense or operating profit outlook, or its 2028 revenue or profitability targets.
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Analyst Views on EOLS
Wall Street analysts forecast EOLS stock price to rise
5 Analyst Rating
4 Buy
1 Hold
0 Sell
Strong Buy
Current: 6.940
Low
18.00
Averages
19.25
High
20.00
Current: 6.940
Low
18.00
Averages
19.25
High
20.00
About EOLS
Evolus, Inc. is a performance beauty company. Its primary market is the cash-pay aesthetic market, which consists of medical products. Its product candidates represent two of the product categories within medical aesthetics, injectable neurotoxins and injectable hyaluronic acid gels. Its product candidates include Jeuveau and Evolysse. Jeuveau is its commercially available proprietary 900 kilodalton (kDa), purified botulinum toxin type A formulation indicated for the temporary improvement in the appearance of moderate to severe glabellar lines, also known as frown lines, in adults. Jeuveau offers a 900kDa botulinum toxin alternative to BOTOX (onabotulinumtoxinA). Jeuveau is available in the United States, Canada, and certain European markets. Evolysse is a line of hyaluronic acid dermal fillers which utilizes first-generation cold technology. The line includes a variety of products, including mid face, nasolabial folds, lips and eyes in the United States and Europe.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Evolus Partners with IBSA for Profhilo® U.S. Launch
- Market Leader Introduction: Evolus has entered into an exclusive licensing and distribution agreement with Swiss IBSA to develop and commercialize Profhilo® in the U.S., a product that has become the market leader in injectable skin quality in Europe, with over 4.8 million treatments administered globally, indicating strong market potential.
- Strategic Market Expansion: By introducing Profhilo®, Evolus enhances its injectable portfolio and enters the rapidly growing and underpenetrated U.S. skin quality treatment market, addressing consumer demand for natural-looking and regenerative outcomes, which holds significant strategic importance.
- No Upfront Payment Economic Model: The agreement employs a transfer pricing model, with Evolus responsible for development activities required for U.S. regulatory approval and subsequent commercialization, and is not expected to impact the company's 2026 revenue and profit outlook, reflecting a disciplined, capital-efficient business development strategy.
- Strengthening Industry Leadership: By adding Profhilo® to its offerings, Evolus not only expands its product line beyond neurotoxins and dermal fillers but also reinforces its leadership position in the aesthetics industry, aiming for sustainable long-term value creation through a differentiated product portfolio.
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- Platform Advantage: The company's CXU™ extracellular matrix platform is designed to scale across multiple markets without reformulation, a structural advantage that sets it apart from early-stage regenerative medicine companies and may lay the groundwork for future market share expansion.
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- Webcast Replay Availability: A replay of the presentation will be available for 90 days post-event, ensuring that investors who cannot attend live can still access the information, thereby improving transparency and information dissemination.
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See More
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- Product Diversity: The Estyme® collection includes Estyme®Smooth, Estyme®Form, Estyme®Lips, and Estyme®Sculpt, the latter of which is anticipated to receive FDA approval in the U.S., addressing the strong demand for mid-face volumizing treatments and enhancing the competitiveness of the company's product portfolio.
- Technological Innovation: Estyme®Sculpt utilizes Symatese's Cold-X® technology designed to preserve the natural structure of the hyaluronic acid molecule, providing long-lasting and natural-looking results, which will enhance practitioners' flexibility in treatments and patient satisfaction.
- Market Potential: The launch of Estyme® is expected to double Evolus's addressable market in the dermal filler category, supporting the company's strategic goal of becoming a global leader in multi-product aesthetics, thereby further solidifying its position in the industry.
See More
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- Market Leader Introduction: Evolus has entered into an exclusive licensing and distribution agreement with Swiss IBSA to develop and commercialize Profhilo® in the U.S., a product that has become the market leader in injectable skin quality in Europe, with over 4.8 million treatments administered globally, indicating strong market potential.
- Strategic Market Expansion: By introducing Profhilo®, Evolus enhances its injectable portfolio and enters the rapidly growing and underpenetrated U.S. skin quality treatment market, addressing consumer demand for natural-looking and regenerative outcomes, which holds significant strategic importance.
- No Upfront Payment Economic Model: The agreement employs a transfer pricing model, with Evolus responsible for development activities required for U.S. regulatory approval and subsequent commercialization, and is not expected to impact the company's 2026 revenue and profit outlook, reflecting a disciplined, capital-efficient business development strategy.
- Strengthening Industry Leadership: By adding Profhilo® to its offerings, Evolus not only expands its product line beyond neurotoxins and dermal fillers but also reinforces its leadership position in the aesthetics industry, aiming for sustainable long-term value creation through a differentiated product portfolio.
See More
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- Porch Group Options Volume: Today, Porch Group Inc (PRCH) options have reached a trading volume of 10,284 contracts, equivalent to approximately 1 million shares, representing 50.9% of its average daily trading volume of 2 million shares over the past month, indicating a significant increase in market interest.
- High Call Option Activity: Within PRCH, the $17.50 strike call option has been particularly active, with 5,005 contracts traded today, representing about 500,500 underlying shares, suggesting that investors are increasingly optimistic about future price increases.
- Zscaler Options Dynamics: Concurrently, Zscaler Inc (ZS) options are also showing strong performance, with a trading volume of 23,193 contracts, equivalent to approximately 2.3 million shares, accounting for 49.9% of its average daily trading volume of 4.7 million shares, reflecting robust market interest.
- Concentrated Call Option Trading: For ZS, the $162.50 strike call option has seen a trading volume of 1,502 contracts, representing about 150,200 underlying shares, indicating a bullish sentiment among investors regarding the stock's future performance.
See More
Conexeu Sciences Inc. Begins Trading on Nasdaq
- Listing Milestone: Conexeu Sciences Inc. commenced trading on Nasdaq on May 21, 2026, marking a significant advancement for the preclinical-stage company centered around its CXU™ bioregenerative platform, which is expected to attract more investment for product development.
- Innovative Platform: The CXU™ is a patented bioregenerative extracellular matrix designed to restore soft tissue lost due to injury, aging, and GLP-1-related weight loss, with its first product, Ten Minute Tissue™, demonstrating enhanced healing dynamics and a low inflammatory profile in preclinical studies, potentially garnering significant market interest.
- Market Outlook: Conexeu enters a public market that is showing genuine commercial momentum, with competitors like Integra LifeSciences and Bioventus exceeding expectations in recent earnings reports, indicating strong demand in the regenerative medicine sector, and the listing is likely to enhance Conexeu's market share.
- Strategic Positioning: The listing not only provides Conexeu with the opportunity for capital formation but also enables the advancement of the CXU™ platform across multiple product lines, with plans to submit a 510(k) application in early 2027, further solidifying its position in the regenerative medicine field.
See More
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- Listing Milestone: Conexeu Sciences Inc. commenced trading on Nasdaq on May 21, 2026, marking its entry into public markets as a regenerative tissue platform company, which is expected to drive business growth in wound care and aesthetic medicine sectors.
- Platform Advantage: The company's CXU™ extracellular matrix platform is designed to scale across multiple markets without reformulation, a structural advantage that sets it apart from early-stage regenerative medicine companies and may lay the groundwork for future market share expansion.
- Innovative Reconstruction Method: Conexeu's B.R.E.A.S.T.™ matrix is a 3D bioprinted scaffold designed to support the body's own tissue regeneration rather than serve as a permanent implant, representing a potential paradigm shift for over 100,000 U.S. women undergoing mastectomies annually.
- Intellectual Property Protection: Conexeu holds issued patents across the U.S., E.U., Japan, and Australia with no royalty or licensing obligations, providing the freedom to expand into new indications and potentially accelerating its 510(k) submission process.
See More
Evolus to Host Investor Meetings at Jefferies Conference
- Management Participation: Evolus's management team will participate in a fireside chat at the upcoming Jefferies Global Healthcare Conference on June 4, 2026, showcasing their expertise in aesthetics and likely attracting investor interest.
- Fireside Chat Timing: Scheduled for 12:50 PM ET, the chat will be accessible via the Investor Relations page on Evolus's website, enhancing interaction between the company and its investors.
- Webcast Replay Availability: A replay of the presentation will be available for 90 days post-event, ensuring that investors who cannot attend live can still access the information, thereby improving transparency and information dissemination.
- Company Background: Evolus is a global performance beauty company focused on redefining the aesthetic injectable market through its unique customer-centric business model and innovative digital platform, aiming to become a leader in the field.
See More
Evolus Launches Estyme® Injectable Products in Europe
- International Market Expansion: Evolus is set to commercially launch its Estyme® injectable hyaluronic acid gel collection on May 16, marking its entry into the international dermal filler market, which is expected to significantly enhance the company's market share in the global aesthetics sector.
- Product Diversity: The Estyme® collection includes Estyme®Smooth, Estyme®Form, Estyme®Lips, and Estyme®Sculpt, the latter of which is anticipated to receive FDA approval in the U.S., addressing the strong demand for mid-face volumizing treatments and enhancing the competitiveness of the company's product portfolio.
- Technological Innovation: Estyme®Sculpt utilizes Symatese's Cold-X® technology designed to preserve the natural structure of the hyaluronic acid molecule, providing long-lasting and natural-looking results, which will enhance practitioners' flexibility in treatments and patient satisfaction.
- Market Potential: The launch of Estyme® is expected to double Evolus's addressable market in the dermal filler category, supporting the company's strategic goal of becoming a global leader in multi-product aesthetics, thereby further solidifying its position in the industry.
See More
