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MESO Overview

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Intellectia

Loading chart...

High
15.330
Open
15.320
VWAP
15.14
Vol
129.45K
Mkt Cap
2.01B
Low
15.020
Amount
1.96M
EV/EBITDA(TTM)
--
Total Shares
128.85M
EV
1.98B
EV/OCF(TTM)
--
P/S(TTM)
30.72
Mesoblast Limited is an Australia-based company. The Company is engaged in developing allogeneic (off-the-shelf) cellular medicines for the treatment of severe and life-threatening inflammatory conditions. The Company has developing a range of late-stage product candidates, derived from its first and second generation proprietary mesenchymal lineage cell therapy technology platforms therapies for distinct indications. The Company’s Ryoncil (remestemcel-L-rknd) is an allogeneic bone marrow-derived mesenchymal stromal cell (MSC) therapy. Its other product candidate is Revascor (rexlemestrocel-L). Rexlemestrocel-L is second generation mesenchymal lineage precursor cell product platform and is in late-stage development for treatment of: chronic heart failure (chf) and chronic low back pain (clbp) due to degenerative disc disease. The two products have been commercialized in Japan and Europe by the Company's licensees.
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Events Timeline

(ET)
2026-03-12
08:50:00
KDK and Others See Significant Increases in Liquidity Borrow Rates
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2026-01-28 (ET)
2026-01-28
08:50:00
Significant Increases in Indicative Borrow Rates for Liquid Options
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2026-01-19 (ET)
2026-01-19
13:50:00
Mesoblast Submits FDA Feedback for rexlemestrocel-L Application
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2026-01-02 (ET)
2026-01-02
05:10:00
Mesoblast Appoints Philip Facchina as New Non-Executive Chair
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2025-11-20 (ET)
2025-11-20
18:38:16
Mesoblast partners with BMT CTN for Ryoncil trial in acute GvHD
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2025-11-17 (ET)
2025-11-17
05:40:51
James O'Brien Named CFO of Mesoblast
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2025-10-06 (ET)
2025-10-06
19:28:03
Mesoblast Announces 66% Year-over-Year Increase in Q2 Ryoncil Revenue
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2025-10-03 (ET)
2025-10-03
05:25:52
Mesoblast Secures J-Code for Ryoncil from Medicare and Medicaid Services
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News

PRnewswire
8.5
03-03PRnewswire
Avaí Bio Advances Cell Therapy Production Milestone
  • Market Potential: The global cell therapy market is projected to exceed $8.2 billion by 2026, driven by clinical breakthroughs and manufacturing milestones, indicating strong growth potential in regenerative medicine.
  • CAR T-Cell Therapy Growth: The market value of CAR T-cell therapy is nearly $7 billion this year, with an 18% compound annual growth rate, suggesting that off-the-shelf platforms are eliminating logistical barriers to patient access, further driving market expansion.
  • Production Milestone Achieved: Avaí Bio and Austrianova's joint venture Klothonova has initiated the production of a Master Cell Bank (MCB) for α-Klotho protein, which will provide critical material for scalable cell therapy production, ensuring product consistency and reducing risks.
  • Anti-Aging Treatment Prospects: By establishing a high-quality MCB, the collaboration between Avaí Bio and Austrianova will support the development of cell-based therapies targeting aging and related diseases, further advancing the clinical application of α-Klotho to meet growing market demand.
Newsfilter
8.5
03-03Newsfilter
Avaí Bio Advances α-Klotho Cell Production Milestone
  • Market Potential: The global cell therapy market is projected to exceed $8.2 billion by 2026, with CAR T-cell therapy valued at nearly $7 billion this year and an 18% compound annual growth rate, indicating robust growth in the regenerative medicine sector.
  • Production Milestone Achieved: Avaí Bio and Austrianova's joint venture Klothonova has successfully initiated the production of a Master Cell Bank (MCB) for α-Klotho protein, ensuring product consistency and safety, thereby laying the groundwork for anti-aging therapies.
  • Significant Technical Advantage: The establishment of the MCB under Good Manufacturing Practices (GMP) not only reduces risks of contamination and genetic instability but also supports sustainable production, reinforcing the company's long-term strategy in the anti-aging sector.
  • Successful Strategic Pivot: Following its rebranding, Avaí Bio has focused on biotechnology, leveraging strategic partnerships with Austrianova to advance both the α-Klotho anti-aging program and the Insulinova diabetes program, showcasing its innovative capabilities in cell therapy.
seekingalpha
9.5
02-27seekingalpha
Mesoblast Reports 1H 2026 Financial Results with Significant Revenue Growth
  • Disappointing Earnings: Mesoblast's 1H 2026 GAAP EPS of -$3.11 missed expectations by $3.06, indicating significant challenges in achieving profitability amid ongoing operational hurdles.
  • Revenue Surge: Despite the disappointing earnings, Mesoblast reported a staggering 1503.1% year-over-year revenue increase to $51.3 million, although it still fell short of the anticipated $54.8 million, highlighting market demand volatility.
  • Ryoncil® Gross Profit Improvement: The gross profit from Ryoncil® reached $44.2 million, a substantial increase from nil in the prior year, suggesting growing market acceptance and sales potential for the product.
  • Direct Selling Costs: Direct selling costs amounted to $7.7 million, which, while relatively high, indicates that the company's investments in sales and marketing are beginning to yield returns as revenue grows.
Newsfilter
9.5
02-27Newsfilter
Mesoblast Reports Strong H1 FY2026 Financial Results Driven by Ryoncil Launch
  • Strong Financial Performance: Mesoblast reported total revenue of $51.3 million for H1 FY2026, a significant increase from $3.2 million in the prior year, indicating that the successful commercialization of Ryoncil® has driven substantial revenue growth for the company.
  • Successful Ryoncil® Launch: The U.S. commercial launch of Ryoncil® generated gross sales of $57.0 million, with net revenue of $48.7 million after adjustments, and a gross profit of $44.2 million against direct selling costs of $7.7 million, reflecting strong market demand and profitability.
  • Increased R&D Investment: The robust operational performance allowed the company to invest in R&D, including supporting a Phase 3 trial for chronic low back pain, aiming to enhance long-term market competitiveness by expanding Ryoncil®'s indications.
  • Improved Cash Flow: As of December 31, 2025, Mesoblast had a cash balance of $130 million and secured a $125 million non-dilutive credit line, with expectations of reduced net cash spend in the future, enhancing financial flexibility to support expansion and clinical programs.
Benzinga
9.0
02-12Benzinga
Ryoncil Demonstrates High Survival Rates in Acute GVHD Treatment
  • Importance of Early Intervention: Ryoncil has demonstrated high survival rates in patients with steroid-refractory acute graft-versus-host disease (SR-aGvHD), emphasizing the need for early use of Ryoncil after steroid resistance to complete the full treatment course and maximize survival chances.
  • Clinical Trial Results: Among 53 patients receiving Ryoncil as ≥ third-line treatment for SR-aGvHD, 15% died before completing the full course, compared to only 2% in the Phase 3 trial as second-line treatment, highlighting the significant advantage of early intervention.
  • First FDA-Approved MSC Product: Ryoncil is the first mesenchymal stromal cell product approved by the U.S. FDA for any indication and the only product approved for children under 12 with steroid-refractory acute graft-versus-host disease, marking a significant breakthrough in this field.
  • Market Performance Analysis: Mesoblast shares are currently trading at $17.73, 1.8% above the 20-day simple moving average but 2.3% below the 50-day moving average, indicating short-term strength while facing medium-term resistance in the market.
Newsfilter
9.0
02-11Newsfilter
Mesoblast Reports Ryoncil® Treatment Data for SR-aGvHD
  • Survival Rate Improvement: At the 2026 ASTCT meeting in Salt Lake City, Mesoblast presented data showing that Ryoncil® achieves high survival rates in steroid-refractory acute graft-versus-host disease (SR-aGvHD) patients, regardless of age, emphasizing the critical importance of early intervention to maximize survival chances.
  • Treatment Outcome Comparison: Among 53 SR-aGvHD patients receiving Ryoncil® as ≥ third-line treatment, 15% died before completing the treatment course, compared to only 2% in the Phase 3 trial receiving it as second-line therapy, highlighting the significant advantages of early treatment.
  • Adult Trial Plans: Mesoblast plans to initiate a pivotal trial for second-line treatment in adults with SR-aGvHD following IRB approval, with enrollment expected to begin this quarter, and if successful, it will support label extension for Ryoncil® in adults, a market approximately three times the size of the pediatric population.
  • Platform Technology Advantage: Ryoncil® is the first FDA-approved mesenchymal stromal cell product for SR-aGvHD treatment, showcasing Mesoblast's leadership in cellular therapies and laying the groundwork for future treatments of other inflammatory diseases.
Wall Street analysts forecast MESO stock price to rise
1 Analyst Rating
Wall Street analysts forecast MESO stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
35.00
Averages
35.00
High
35.00
Current: 0.000
sliders
Low
35.00
Averages
35.00
High
35.00
Jefferies
Hold
to
Buy
upgrade
$3
AI Analysis
2025-11-25
Reason
Jefferies
Price Target
$3
AI Analysis
2025-11-25
upgrade
Hold
to
Buy
Reason
Jefferies upgraded Mesoblast to Buy from Hold with a price target of A$3.30, up from A$3.
Jefferies
David Stanton
Hold
to
Buy
upgrade
$3
2025-11-25
Reason
Jefferies
David Stanton
Price Target
$3
2025-11-25
upgrade
Hold
to
Buy
Reason
As previously reported, Jefferies analyst David Stanton upgraded Mesoblast to Buy from Hold with a price target of A$3.30, up from A$3. Ryoncil continues to be rolled out and the firm forecasts 78 patients will complete therapy in FY26, up from 63, while updating its estimates for fiscal Q2 results and FY26 forecasts.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MESO
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Valuation Metrics

The current forward P/E ratio for Mesoblast Ltd (MESO.O) is -194.58, compared to its 5-year average forward P/E of -19.24. For a more detailed relative valuation and DCF analysis to assess Mesoblast Ltd's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-19.24
Current PE
-194.58
Overvalued PE
15.63
Undervalued PE
-54.11

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.39
Current EV/EBITDA
261.47
Overvalued EV/EBITDA
94.73
Undervalued EV/EBITDA
-101.51

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
29.60
Current PS
21.25
Overvalued PS
46.56
Undervalued PS
12.63

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Frequently Asked Questions

What is Mesoblast Ltd (MESO) stock price today?

The current price of MESO is 15.07 USD — it has decreased -3.58

What is Mesoblast Ltd (MESO)'s business?

Mesoblast Limited is an Australia-based company. The Company is engaged in developing allogeneic (off-the-shelf) cellular medicines for the treatment of severe and life-threatening inflammatory conditions. The Company has developing a range of late-stage product candidates, derived from its first and second generation proprietary mesenchymal lineage cell therapy technology platforms therapies for distinct indications. The Company’s Ryoncil (remestemcel-L-rknd) is an allogeneic bone marrow-derived mesenchymal stromal cell (MSC) therapy. Its other product candidate is Revascor (rexlemestrocel-L). Rexlemestrocel-L is second generation mesenchymal lineage precursor cell product platform and is in late-stage development for treatment of: chronic heart failure (chf) and chronic low back pain (clbp) due to degenerative disc disease. The two products have been commercialized in Japan and Europe by the Company's licensees.

What is the price predicton of MESO Stock?

Wall Street analysts forecast MESO stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MESO is35.00 USD with a low forecast of 35.00 USD and a high forecast of 35.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Mesoblast Ltd (MESO)'s revenue for the last quarter?

Mesoblast Ltd revenue for the last quarter amounts to NaN USD, decreased

What is Mesoblast Ltd (MESO)'s earnings per share (EPS) for the last quarter?

Mesoblast Ltd. EPS for the last quarter amounts to USD, decreased

How many employees does Mesoblast Ltd (MESO). have?

Mesoblast Ltd (MESO) has 81 emplpoyees as of March 12 2026.

What is Mesoblast Ltd (MESO) market cap?

Today MESO has the market capitalization of 2.01B USD.