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MESO Overview

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Intellectia

Loading chart...

High
16.230
Open
15.850
VWAP
16.08
Vol
164.48K
Mkt Cap
1.98B
Low
15.850
Amount
2.64M
EV/EBITDA(TTM)
--
Total Shares
128.85M
EV
2.00B
EV/OCF(TTM)
--
P/S(TTM)
29.24
Mesoblast Limited is an Australia-based company. The Company is engaged in developing allogeneic (off-the-shelf) cellular medicines for the treatment of severe and life-threatening inflammatory conditions. The Company has developing a range of late-stage product candidates, derived from its first and second generation proprietary mesenchymal lineage cell therapy technology platforms therapies for distinct indications. The Company’s Ryoncil (remestemcel-L-rknd) is an allogeneic bone marrow-derived mesenchymal stromal cell (MSC) therapy. Its other product candidate is Revascor (rexlemestrocel-L). Rexlemestrocel-L is second generation mesenchymal lineage precursor cell product platform and is in late-stage development for treatment of: chronic heart failure (chf) and chronic low back pain (clbp) due to degenerative disc disease. The two products have been commercialized in Japan and Europe by the Company's licensees.
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Events Timeline

(ET)
2026-03-30
08:50:00
Grabagun Digital Holdings Borrow Rate Increases to 5.85%
select
2026-03-12 (ET)
2026-03-12
08:50:00
KDK and Others See Significant Increases in Liquidity Borrow Rates
select
2026-01-28 (ET)
2026-01-28
08:50:00
Significant Increases in Indicative Borrow Rates for Liquid Options
select
2026-01-19 (ET)
2026-01-19
13:50:00
Mesoblast Submits FDA Feedback for rexlemestrocel-L Application
select
2026-01-02 (ET)
2026-01-02
05:10:00
Mesoblast Appoints Philip Facchina as New Non-Executive Chair
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2025-11-20 (ET)
2025-11-20
18:38:16
Mesoblast partners with BMT CTN for Ryoncil trial in acute GvHD
select
2025-11-17 (ET)
2025-11-17
05:40:51
James O'Brien Named CFO of Mesoblast
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2025-10-06 (ET)
2025-10-06
19:28:03
Mesoblast Announces 66% Year-over-Year Increase in Q2 Ryoncil Revenue
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News

Globenewswire
8.5
03-18Globenewswire
Avaí Bio Initiates Production of α-Klotho Cell Bank
  • Production Milestone: Avaí Bio, in collaboration with Austrianova, has initiated the production of a Master Cell Bank for the α-Klotho protein, marking a significant transition of its anti-aging program from research to manufacturing, which is expected to enhance the market potential for anti-aging therapies.
  • Market Outlook: The global cell and gene therapy market is projected to surge from $10.4 billion to over $45 billion, with Avaí Bio's dual-program strategy targeting major diseases like Alzheimer's and diabetes, leveraging this growth trend effectively.
  • Technological Edge: Utilizing the Cell-in-a-Box® technology backed by over 50 peer-reviewed studies, Avaí Bio ensures the efficacy of its products in anti-aging and diabetes treatments, thereby enhancing its competitive position in the biotechnology sector.
  • Health Implications: Research links α-Klotho to reduced risks of Alzheimer's, cardiovascular diseases, and certain cancers, and Avaí Bio's products aim to address the therapeutic gap created by the natural decline of α-Klotho levels after age 40, meeting the rising market demand.
PRnewswire
8.5
03-18PRnewswire
Avaí Bio Initiates Production of α-Klotho Cells
  • Production Milestone: Avaí Bio has initiated the manufacturing of a Master Cell Bank for α-Klotho protein in collaboration with Austrianova, marking a significant transition from laboratory theory to production reality, which is expected to enhance the market potential for anti-aging therapies.
  • Broad Market Outlook: The global cell therapy market surpassed $8.2 billion in 2026 and is projected to exceed $45 billion by 2035, positioning Avaí Bio's technology to capture a significant share in this rapidly growing sector.
  • Technological Innovation: The Cell-in-a-Box® technology protects transplanted cells from immune system attacks, allowing them to continuously produce α-Klotho, addressing a critical challenge in cell therapy and enhancing treatment efficacy and safety.
  • Dual-Program Strategy: Avaí Bio is advancing both the Klothonova anti-aging platform and the Insulinova diabetes program, targeting enormous markets such as Alzheimer's disease, cardiovascular diseases, and kidney disease, demonstrating its strategic positioning in the biotechnology field.
Newsfilter
8.5
03-18Newsfilter
Avaí Bio Initiates α-Klotho Cell Production
  • Manufacturing Milestone: Avaí Bio has initiated the production of a Master Cell Bank for α-Klotho protein in collaboration with Austrianova, marking a significant transition from laboratory theory to production reality, which is expected to accelerate the commercialization of anti-aging therapies.
  • Massive Market Potential: The global cell therapy market surpassed $8.2 billion in 2026 and is projected to exceed $45 billion by 2035, positioning Avaí Bio's technology to capture a significant share in this rapidly growing sector.
  • Technological Advantage: The Cell-in-a-Box® technology protects therapeutic cells from immune system attacks, allowing them to continuously produce α-Klotho, addressing the low survival rates of transplanted cells and enhancing the sustainability of treatment outcomes.
  • Strategic Positioning: Avaí Bio's dual-program approach targets both the Klothonova anti-aging platform and the Insulinova diabetes program, with enormous addressable markets, as the Alzheimer's disease market alone is projected to reach $32.8 billion by 2033.
PRnewswire
8.5
03-03PRnewswire
Avaí Bio Advances Cell Therapy Production Milestone
  • Market Potential: The global cell therapy market is projected to exceed $8.2 billion by 2026, driven by clinical breakthroughs and manufacturing milestones, indicating strong growth potential in regenerative medicine.
  • CAR T-Cell Therapy Growth: The market value of CAR T-cell therapy is nearly $7 billion this year, with an 18% compound annual growth rate, suggesting that off-the-shelf platforms are eliminating logistical barriers to patient access, further driving market expansion.
  • Production Milestone Achieved: Avaí Bio and Austrianova's joint venture Klothonova has initiated the production of a Master Cell Bank (MCB) for α-Klotho protein, which will provide critical material for scalable cell therapy production, ensuring product consistency and reducing risks.
  • Anti-Aging Treatment Prospects: By establishing a high-quality MCB, the collaboration between Avaí Bio and Austrianova will support the development of cell-based therapies targeting aging and related diseases, further advancing the clinical application of α-Klotho to meet growing market demand.
Newsfilter
8.5
03-03Newsfilter
Avaí Bio Advances α-Klotho Cell Production Milestone
  • Market Potential: The global cell therapy market is projected to exceed $8.2 billion by 2026, with CAR T-cell therapy valued at nearly $7 billion this year and an 18% compound annual growth rate, indicating robust growth in the regenerative medicine sector.
  • Production Milestone Achieved: Avaí Bio and Austrianova's joint venture Klothonova has successfully initiated the production of a Master Cell Bank (MCB) for α-Klotho protein, ensuring product consistency and safety, thereby laying the groundwork for anti-aging therapies.
  • Significant Technical Advantage: The establishment of the MCB under Good Manufacturing Practices (GMP) not only reduces risks of contamination and genetic instability but also supports sustainable production, reinforcing the company's long-term strategy in the anti-aging sector.
  • Successful Strategic Pivot: Following its rebranding, Avaí Bio has focused on biotechnology, leveraging strategic partnerships with Austrianova to advance both the α-Klotho anti-aging program and the Insulinova diabetes program, showcasing its innovative capabilities in cell therapy.
seekingalpha
9.5
02-27seekingalpha
Mesoblast Reports 1H 2026 Financial Results with Significant Revenue Growth
  • Disappointing Earnings: Mesoblast's 1H 2026 GAAP EPS of -$3.11 missed expectations by $3.06, indicating significant challenges in achieving profitability amid ongoing operational hurdles.
  • Revenue Surge: Despite the disappointing earnings, Mesoblast reported a staggering 1503.1% year-over-year revenue increase to $51.3 million, although it still fell short of the anticipated $54.8 million, highlighting market demand volatility.
  • Ryoncil® Gross Profit Improvement: The gross profit from Ryoncil® reached $44.2 million, a substantial increase from nil in the prior year, suggesting growing market acceptance and sales potential for the product.
  • Direct Selling Costs: Direct selling costs amounted to $7.7 million, which, while relatively high, indicates that the company's investments in sales and marketing are beginning to yield returns as revenue grows.
Wall Street analysts forecast MESO stock price to rise
1 Analyst Rating
Wall Street analysts forecast MESO stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
35.00
Averages
35.00
High
35.00
Current: 0.000
sliders
Low
35.00
Averages
35.00
High
35.00
Jefferies
Hold
to
Buy
upgrade
$3
AI Analysis
2025-11-25
Reason
Jefferies
Price Target
$3
AI Analysis
2025-11-25
upgrade
Hold
to
Buy
Reason
Jefferies upgraded Mesoblast to Buy from Hold with a price target of A$3.30, up from A$3.
Jefferies
David Stanton
Hold
to
Buy
upgrade
$3
2025-11-25
Reason
Jefferies
David Stanton
Price Target
$3
2025-11-25
upgrade
Hold
to
Buy
Reason
As previously reported, Jefferies analyst David Stanton upgraded Mesoblast to Buy from Hold with a price target of A$3.30, up from A$3. Ryoncil continues to be rolled out and the firm forecasts 78 patients will complete therapy in FY26, up from 63, while updating its estimates for fiscal Q2 results and FY26 forecasts.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MESO
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Valuation Metrics

The current forward P/E ratio for Mesoblast Ltd (MESO.O) is 464.64, compared to its 5-year average forward P/E of 6.38. For a more detailed relative valuation and DCF analysis to assess Mesoblast Ltd's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
6.38
Current PE
464.64
Overvalued PE
124.46
Undervalued PE
-111.70

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.61
Current EV/EBITDA
-1.93
Overvalued EV/EBITDA
92.15
Undervalued EV/EBITDA
-99.38

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
28.50
Current PS
5.79
Overvalued PS
45.90
Undervalued PS
11.11

Financials

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Frequently Asked Questions

What is Mesoblast Ltd (MESO) stock price today?

The current price of MESO is 16.15 USD — it has increased 5.01

What is Mesoblast Ltd (MESO)'s business?

Mesoblast Limited is an Australia-based company. The Company is engaged in developing allogeneic (off-the-shelf) cellular medicines for the treatment of severe and life-threatening inflammatory conditions. The Company has developing a range of late-stage product candidates, derived from its first and second generation proprietary mesenchymal lineage cell therapy technology platforms therapies for distinct indications. The Company’s Ryoncil (remestemcel-L-rknd) is an allogeneic bone marrow-derived mesenchymal stromal cell (MSC) therapy. Its other product candidate is Revascor (rexlemestrocel-L). Rexlemestrocel-L is second generation mesenchymal lineage precursor cell product platform and is in late-stage development for treatment of: chronic heart failure (chf) and chronic low back pain (clbp) due to degenerative disc disease. The two products have been commercialized in Japan and Europe by the Company's licensees.

What is the price predicton of MESO Stock?

Wall Street analysts forecast MESO stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MESO is35.00 USD with a low forecast of 35.00 USD and a high forecast of 35.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Mesoblast Ltd (MESO)'s revenue for the last quarter?

Mesoblast Ltd revenue for the last quarter amounts to NaN USD, decreased

What is Mesoblast Ltd (MESO)'s earnings per share (EPS) for the last quarter?

Mesoblast Ltd. EPS for the last quarter amounts to USD, decreased

How many employees does Mesoblast Ltd (MESO). have?

Mesoblast Ltd (MESO) has 81 emplpoyees as of April 01 2026.

What is Mesoblast Ltd (MESO) market cap?

Today MESO has the market capitalization of 1.98B USD.