Enliven Therapeutics Executive Sells 20,000 Shares
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1h ago
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Source: Fool
- Executive Sale Details: Chief Scientific Officer Joseph P. Lyssikatos sold 20,000 shares of Enliven Therapeutics on January 20, 2026, for approximately $535,100, indicating a potential shift in confidence regarding the company's stock.
- Transaction Context: This sale exceeds Mr. Lyssikatos's historical median sale of 11,114 shares, suggesting a significant increase in the scale of this transaction, which may raise investor concerns about his future intentions with the stock.
- Company Financial Overview: Enliven Therapeutics has a market capitalization of $1.57 billion, and despite a net loss of $97.21 million, the stock surged approximately 71% in January following positive initial data for its ELVN-001 leukemia treatment, reflecting optimistic market sentiment about its future prospects.
- Clinical Trial Advancements: The company aims to advance ELVN-001 to phase three clinical trials in collaboration with the FDA, and although still in its early stages, the stock is rated as a “strong buy” by most Wall Street analysts, indicating confidence in its growth trajectory.
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Analyst Views on ELVN
Wall Street analysts forecast ELVN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ELVN is 40.20 USD with a low forecast of 35.00 USD and a high forecast of 48.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
6 Analyst Rating
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 25.670
Low
35.00
Averages
40.20
High
48.00
Current: 25.670
Low
35.00
Averages
40.20
High
48.00
About ELVN
Enliven Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the discovery and development of small molecule inhibitors to help patients with cancer. It is advancing two parallel lead product candidates, ELVN-001 and ELVN-002, and pursuing several additional research stage opportunities that align with its development approach. Its first product candidate, ELVN-001, is a potent, highly selective, small molecule kinase inhibitor designed to specifically target the breakpoint cluster region-Abelson (BCR-ABL) gene fusion, the oncogenic driver for patients with chronic myeloid leukemia. Its second product candidate, ELVN-002, is a potent, highly selective, central nervous system penetrant and irreversible human epidermal growth factor receptor 2 (HER2) inhibitor with activity against wild type HER2 and various HER2 mutations. ELVN-002 is designed to inhibit wild type HER2 and key mutations of HER2, while sparing wild-type EGFR and avoiding EGFR-related toxicities.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Enliven Therapeutics Executive Sells 20,000 Shares
- Executive Sale Details: Chief Scientific Officer Joseph P. Lyssikatos sold 20,000 shares of Enliven Therapeutics on January 20, 2026, for approximately $535,100, indicating a potential shift in confidence regarding the company's stock.
- Transaction Context: This sale exceeds Mr. Lyssikatos's historical median sale of 11,114 shares, suggesting a significant increase in the scale of this transaction, which may raise investor concerns about his future intentions with the stock.
- Company Financial Overview: Enliven Therapeutics has a market capitalization of $1.57 billion, and despite a net loss of $97.21 million, the stock surged approximately 71% in January following positive initial data for its ELVN-001 leukemia treatment, reflecting optimistic market sentiment about its future prospects.
- Clinical Trial Advancements: The company aims to advance ELVN-001 to phase three clinical trials in collaboration with the FDA, and although still in its early stages, the stock is rated as a “strong buy” by most Wall Street analysts, indicating confidence in its growth trajectory.

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Enliven Therapeutics COO Anish Patel Sells 48,300 Shares for $1,351,000
- Executive Sell-off: Enliven Therapeutics COO Anish Patel sold 48,300 shares on January 9, 2026, totaling $1,351,000, which may raise concerns about the company's future outlook among investors.
- Market Reaction: Executive sell-offs are often perceived as negative signals for stock performance, potentially leading to a decline in investor confidence in Enliven Therapeutics and affecting its stock price.
- Shareholder Structure Change: This sell-off could alter the company's shareholder structure, impacting investor trust in corporate governance and management, which may affect the company's financing capabilities and market image.
- Future Outlook: While the sell-off raises concerns, the company's future strategic direction and performance will remain focal points for investors, necessitating close monitoring of upcoming earnings reports and market developments.

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