Dow Jones Futures Steady, S&P 500 and Nasdaq Futures Decline Modestly
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jun 04 2026
0mins
Source: Yahoo Finance
- Futures Market Movement: Dow Jones futures remained little changed in after-hours trading, while S&P 500 and Nasdaq futures experienced modest declines, reflecting market caution ahead of upcoming economic data, particularly the May jobs report.
- Jobs Report Anticipation: The market is keenly awaiting the May jobs report set to be released before Friday's open, as investors look to gauge the strength of the economic recovery and its implications for future monetary policy.
- IPO Inclusion Standards: S&P Dow Jones Indices announced late Thursday that it will not fast-track SpaceX and other upcoming megacap IPOs, such as Anthropic and OpenAI, into the benchmark index, which may impact market performance and investor confidence in these companies.
- Market Sentiment Analysis: Given the anticipation surrounding employment data and changes in IPO inclusion standards, market sentiment remains cautious, with investors likely adopting a wait-and-see approach to assess future investment opportunities.
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Analyst Views on LLY
Wall Street analysts forecast LLY stock price to rise
20 Analyst Rating
18 Buy
2 Hold
0 Sell
Strong Buy
Current: 1112.000
Low
950.00
Averages
1192
High
1500
Current: 1112.000
Low
950.00
Averages
1192
High
1500
About LLY
Eli Lilly and Company is a medicine company, which discovers, develops, manufactures, and market products in a single business segment called human pharmaceutical products. The Company manufacture and distribute its products through facilities in the United States, including Puerto Rico, and in Europe and Asia. The Company’s products are sold in approximately 90 countries. Its Cardiometabolic Health products Basaglar; Humalog, Humalog Mix 75/25, Humalog U-100, Humalog U-200, Humalog Mix 50/50, insulin lispro, and others; Humulin, Humulin 70/30, and others; Jardiance; Mounjaro; Trulicity; Zepbound, and others. Its oncology products include Cyramza, Erbitux, Tyvyt, Verzenio, Retevmo, Jaypirca, and others. Its immunology products include Ebglyss, Olumiant, Omvoh, and Taltz. Its neuroscience products include Emgality and Kisunla. Its LillyDirect, a direct-to-patient digital health care platform, provides delivery of select Lilly medicines dispensed by third-party pharmacies to patients.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- AI Innovation at Eli Lilly: Eli Lilly is collaborating with OpenAI to accelerate drug discovery and has established an AI co-innovation lab with Nvidia, aiming to identify promising molecules faster than traditional methods, which is expected to enhance its competitive edge in drug development.
- Strong Financial Performance: In Q1 2026, Eli Lilly reported a 56% revenue increase to $19.8 billion and a 168% surge in net income to $7.4 billion, demonstrating the company's ability to achieve high growth efficiency despite its large scale, further solidifying its market position.
- Growth Potential for Twist: Twist Bioscience's revenue rose 19% to $110.7 million in Q2 of fiscal 2026, marking 13 consecutive quarters of growth; however, its net loss widened to $44 million, yet the partnership with Amazon provides significant momentum for future drug development.
- Market Outlook Analysis: Both companies showcase distinct approaches in AI-driven drug development, with Eli Lilly focusing on innovation in established drugs while Twist seeks higher-risk returns in synthetic DNA, reflecting the broad potential of AI in the pharmaceutical industry.
See More
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- AI Innovation at Eli Lilly: Eli Lilly collaborates with OpenAI for drug discovery and establishes an AI co-innovation lab with Nvidia, aiming to accelerate drug development and enhance its position in the competitive pharmaceutical market.
- Strong Financial Performance: In Q1 2026, Eli Lilly reported a 56% revenue increase to $19.8 billion and a 168% surge in net income to $7.4 billion, indicating improved operational efficiency and promising future growth potential despite its large scale.
- Market Dynamics for Twist Bioscience: Twist Bioscience's revenue rose 19% to $110.7 million in Q2 2026, marking 13 consecutive quarters of growth, although net losses widened to $44 million, highlighting challenges faced during expansion.
- Partnership with Amazon: Twist Bioscience has become a key lab in Amazon's Bio Discovery platform, leveraging AI to design drugs and collaborate with real-world partners, which is expected to create new business growth opportunities and enhance its market competitiveness.
See More
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- AI Innovation at Eli Lilly: Eli Lilly collaborates with OpenAI for drug discovery and establishes an AI co-innovation lab with Nvidia to accelerate the identification of promising drug molecules, resulting in a 56% revenue increase to $19.8 billion and a 168% rise in net income to $7.4 billion in Q1 2026, indicating significant efficiency improvements.
- New Drug Potential: Lilly's newly approved weight-loss pill, Foundayo, which can be taken at any time, replaces injections and is expected to attract a broader patient base, further expanding market share and enhancing the company's position in the rapidly growing weight-loss drug market.
- Twist's Growth Risks: Twist Bioscience's stock has risen over 136% in the past year, despite a 26% decline over the past five years, with Q2 2026 revenue up 19% to $110.7 million, marking 13 consecutive quarters of revenue growth, although net loss widened to $44 million primarily due to a $7.2 million settlement.
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See More
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- Stock Volatility: The company's stock plummeted 23% earlier this month and dropped 36% in March due to lower-than-expected efficacy of another drug, petrelintide, marking the two worst performances since its IPO in 2010, with a year-to-date decline of 38%.
- Shift in Market Focus: Despite the bleak outlook for survodutide, investors are shifting their attention to petrelintide, with analysts believing it still holds potential in the weight loss market, especially with upcoming late-stage trials.
- Increased Competitive Pressure: At the American Diabetes Association meeting, amylin drugs like petrelintide were highlighted as key future players, and despite competition from major firms like Eli Lilly, Zealand Pharma still has opportunities to carve out a niche in the obesity market.
See More
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- Drug Efficacy Issues: Zealand Pharma's obesity drug survodutide faced significant setbacks with a 19% patient dropout rate, prompting analysts to slash peak sales forecasts by nearly 80%, which will severely impact the company's market performance and investor confidence.
- Optimistic Outlook for New Drug: Despite disappointing tolerability data for survodutide, analysts remain positive about the amylin-based drug petrelintide, believing it has the potential for modest weight loss and excellent tolerability, positioning it as a future growth driver.
- Intensifying Market Competition: At the American Diabetes Association meeting, the demand for amylin drugs was widely recognized, and Zealand's petrelintide faces competition from major players like Eli Lilly, necessitating a clear differentiation to attract patients in a crowded market.
- Crucial Future Trials: Petrelintide is set to initiate late-stage trials in the second half of the year, and analysts believe its success will directly influence Zealand's market position, particularly in the treatment of obesity and fatty liver disease.
See More
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- Investment Strategy Analysis: Cathie Wood resumed buying after four days of selling, adding to positions in stocks like Eli Lilly, Block, and Coinbase, reflecting her strategy of seeking investment opportunities during market volatility, particularly by increasing stakes when prices drop to achieve higher returns.
See More
Eli Lilly and Twist Leverage AI to Accelerate Drug Development
- AI Innovation at Eli Lilly: Eli Lilly is collaborating with OpenAI to accelerate drug discovery and has established an AI co-innovation lab with Nvidia, aiming to identify promising molecules faster than traditional methods, which is expected to enhance its competitive edge in drug development.
- Strong Financial Performance: In Q1 2026, Eli Lilly reported a 56% revenue increase to $19.8 billion and a 168% surge in net income to $7.4 billion, demonstrating the company's ability to achieve high growth efficiency despite its large scale, further solidifying its market position.
- Growth Potential for Twist: Twist Bioscience's revenue rose 19% to $110.7 million in Q2 of fiscal 2026, marking 13 consecutive quarters of growth; however, its net loss widened to $44 million, yet the partnership with Amazon provides significant momentum for future drug development.
- Market Outlook Analysis: Both companies showcase distinct approaches in AI-driven drug development, with Eli Lilly focusing on innovation in established drugs while Twist seeks higher-risk returns in synthetic DNA, reflecting the broad potential of AI in the pharmaceutical industry.
See More
Eli Lilly and Twist Bioscience: AI in Drug Development
- AI Innovation at Eli Lilly: Eli Lilly collaborates with OpenAI for drug discovery and establishes an AI co-innovation lab with Nvidia, aiming to accelerate drug development and enhance its position in the competitive pharmaceutical market.
- Strong Financial Performance: In Q1 2026, Eli Lilly reported a 56% revenue increase to $19.8 billion and a 168% surge in net income to $7.4 billion, indicating improved operational efficiency and promising future growth potential despite its large scale.
- Market Dynamics for Twist Bioscience: Twist Bioscience's revenue rose 19% to $110.7 million in Q2 2026, marking 13 consecutive quarters of growth, although net losses widened to $44 million, highlighting challenges faced during expansion.
- Partnership with Amazon: Twist Bioscience has become a key lab in Amazon's Bio Discovery platform, leveraging AI to design drugs and collaborate with real-world partners, which is expected to create new business growth opportunities and enhance its market competitiveness.
See More
Eli Lilly and Twist Bioscience's AI Drug Development Strategies
- AI Innovation at Eli Lilly: Eli Lilly collaborates with OpenAI for drug discovery and establishes an AI co-innovation lab with Nvidia to accelerate the identification of promising drug molecules, resulting in a 56% revenue increase to $19.8 billion and a 168% rise in net income to $7.4 billion in Q1 2026, indicating significant efficiency improvements.
- New Drug Potential: Lilly's newly approved weight-loss pill, Foundayo, which can be taken at any time, replaces injections and is expected to attract a broader patient base, further expanding market share and enhancing the company's position in the rapidly growing weight-loss drug market.
- Twist's Growth Risks: Twist Bioscience's stock has risen over 136% in the past year, despite a 26% decline over the past five years, with Q2 2026 revenue up 19% to $110.7 million, marking 13 consecutive quarters of revenue growth, although net loss widened to $44 million primarily due to a $7.2 million settlement.
- Partnership with Amazon: Twist's collaboration with Amazon positions it as a key lab in the Amazon Bio Discovery platform, leveraging AI to design drugs and develop them with real-world partners, highlighting the company's critical role in AI-driven drug development despite facing higher uncertainty.
See More
Zealand Pharma Shares Plunge 23% Amid Survodutide Concerns
- Drug Efficacy Concerns: Zealand Pharma's weight loss drug, survodutide, has shown a 19% patient dropout rate due to side effects in clinical trials, prompting analysts to slash peak sales forecasts by nearly 80%, posing a significant challenge to the company's obesity treatment strategy.
- Stock Volatility: The company's stock plummeted 23% earlier this month and dropped 36% in March due to lower-than-expected efficacy of another drug, petrelintide, marking the two worst performances since its IPO in 2010, with a year-to-date decline of 38%.
- Shift in Market Focus: Despite the bleak outlook for survodutide, investors are shifting their attention to petrelintide, with analysts believing it still holds potential in the weight loss market, especially with upcoming late-stage trials.
- Increased Competitive Pressure: At the American Diabetes Association meeting, amylin drugs like petrelintide were highlighted as key future players, and despite competition from major firms like Eli Lilly, Zealand Pharma still has opportunities to carve out a niche in the obesity market.
See More
Zealand Pharma Faces Setbacks, Analysts Reassess Obesity Drug Strategy
- Drug Efficacy Issues: Zealand Pharma's obesity drug survodutide faced significant setbacks with a 19% patient dropout rate, prompting analysts to slash peak sales forecasts by nearly 80%, which will severely impact the company's market performance and investor confidence.
- Optimistic Outlook for New Drug: Despite disappointing tolerability data for survodutide, analysts remain positive about the amylin-based drug petrelintide, believing it has the potential for modest weight loss and excellent tolerability, positioning it as a future growth driver.
- Intensifying Market Competition: At the American Diabetes Association meeting, the demand for amylin drugs was widely recognized, and Zealand's petrelintide faces competition from major players like Eli Lilly, necessitating a clear differentiation to attract patients in a crowded market.
- Crucial Future Trials: Petrelintide is set to initiate late-stage trials in the second half of the year, and analysts believe its success will directly influence Zealand's market position, particularly in the treatment of obesity and fatty liver disease.
See More
Cathie Wood Resumes Buying After IPO Surge
- Eli Lilly Performance: Despite a 1.43% drop on Wednesday, Eli Lilly (LLY) has surged 40% over the past year, briefly exceeding a $1 trillion market cap, driven by strong growth in GLP-1 drugs, with 2023 revenue expected to rise by 26% to 30%.
- Block's Current Status: Block (XYZ) shares rose 2.75%, with a market cap of $43 billion; although its stock has been flat over the past year, revenue growth has accelerated over the last four quarters, indicating future growth potential, and the current high P/E ratio offers a good entry point for investors.
- Coinbase's Challenges: Coinbase (COIN) shares fell 2.33%, with a 37% decline over the past year due to weak demand for Bitcoin and other cryptocurrencies, leading to a 22% and 31% drop in revenue over the last two quarters, with profitability expected to decline sharply for the second consecutive year.
- Investment Strategy Analysis: Cathie Wood resumed buying after four days of selling, adding to positions in stocks like Eli Lilly, Block, and Coinbase, reflecting her strategy of seeking investment opportunities during market volatility, particularly by increasing stakes when prices drop to achieve higher returns.
See More
