Compass Therapeutics Updates on Clinical Progress and Leadership Changes
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 06 2026
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Compass Therapeutics provided a general business update highlighting progress throughout its pipeline of clinical-stage drug candidates. The analyses of progression-free survival and overall survival remain on track for late Q1 2026 in the ongoing Phase 2/3 COMPANION-002 study of tovecimig in patients with advanced biliary tract cancer. In the ongoing Phase 1 dose-escalation study of CTX-8371, a previously reported third response has now been confirmed in a patient with Hodgkin Lymphoma. CTX-8371 has demonstrated responses in patients with both solid tumor and hematologic malignancies. Also in the CTX-8371 Phase 1 study, the previously disclosed deep partial response in a patient with triple negative breast cancer is now durable through week 32. Initiation of a Phase 1 study of CTX-10726 is expected in Q1 2026 with initial data from this study expected in H2 2026. Compass expanded its senior leadership team with the appointment of Arjun Prasad, MBA, MPH, as Chief Commercial Officer and Cynthia Sirard, MD, as Chief Medical Officer. Data from tovecimig's Phase 2 study in patients with colorectal cancer will be presented at the 2026 ASCO GI Cancers Symposium. Estimated $209 million in cash and marketable securities as of December 31, 2025, which is expected to provide cash runway into 2028
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Analyst Views on CMPX
Wall Street analysts forecast CMPX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CMPX is 12.67 USD with a low forecast of 8.00 USD and a high forecast of 24.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
8 Analyst Rating
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 6.160
Low
8.00
Averages
12.67
High
24.00
Current: 6.160
Low
8.00
Averages
12.67
High
24.00
About CMPX
Compass Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company. The Company is developing proprietary antibody-based therapeutics to treat multiple human diseases. Its pipeline of novel product candidates is designed to target multiple critical biological pathways required for an effective anti-tumor response. Its lead product candidate, tovecimig, is a bispecific antibody targeting Delta-like ligand 4 (DLL4), a ligand of Notch-1, and vascular endothelial growth factor A (VEGF-A). Its second program, CTX-471, is an agonistic antibody targeting a member of the tumor necrosis factor receptor superfamily member 9 (TNFRSF9), also known as CD-137, a co-stimulatory receptor which is mostly expressed on activated, but not on resting T-cells and NK cells. Its third program, CTX-8371, is a bispecific antibody targeting the programmed cell death protein-1 (PD-1), an inhibitory immune checkpoint receptor, and its ligand PD-L1, two validated immune-oncology targets.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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