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CMPX Overview

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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
1.910
Open
1.780
VWAP
1.85
Vol
4.23M
Mkt Cap
329.56M
Low
1.780
Amount
7.81M
EV/EBITDA(TTM)
--
Total Shares
180.09M
EV
134.87M
EV/OCF(TTM)
--
P/S(TTM)
--
Compass Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company. The Company is developing proprietary antibody-based therapeutics to treat multiple human diseases. Its pipeline of novel product candidates is designed to target multiple critical biological pathways required for an effective anti-tumor response. Its lead product candidate, tovecimig, is a bispecific antibody targeting Delta-like ligand 4 (DLL4), a ligand of Notch-1, and vascular endothelial growth factor A (VEGF-A). Its second program, CTX-471, is an agonistic antibody targeting a member of the tumor necrosis factor receptor superfamily member 9 (TNFRSF9), also known as CD-137, a co-stimulatory receptor which is mostly expressed on activated, but not on resting T-cells and NK cells. Its third program, CTX-8371, is a bispecific antibody targeting the programmed cell death protein-1 (PD-1), an inhibitory immune checkpoint receptor, and its ligand PD-L1, two validated immune-oncology targets.
Show More

Events Timeline

(ET)
2026-05-05
08:10:00
Thomas Schuetz: Positive Tovecimig Study Data, Looking Forward to Meeting with FDA
select
2026-04-27 (ET)
2026-04-27
16:20:00
Major Averages Close Mixed Amid Escalating Geopolitical Tensions
select
2026-04-27
12:00:00
Major Averages Decline Amid Stalled US-Iran Peace Talks
select

News

seekingalpha
9.5
05-05seekingalpha
Compass Therapeutics Reports Q1 Results with Cash Runway Until 2028
  • Financial Performance: Compass Therapeutics reported a Q1 2026 GAAP EPS of -$0.10, aligning with market expectations, indicating stability in financial management despite ongoing losses.
  • Cash Position: As of March 31, 2026, the company held $195 million in cash and marketable securities, down from $209 million on December 31, 2025, representing a $14 million decrease; however, the anticipated cash runway extends into 2028, ensuring operational stability.
  • Cash Usage in Operations: During the first quarter, Compass utilized $18 million in net cash for operating activities, partially offset by $4 million from common stock exercises, reflecting ongoing investments in R&D and operations.
  • Market Reaction: Despite positive secondary endpoint results from the COMPANION-002 study, the stock price of Compass Therapeutics fell due to missing the overall survival endpoint, indicating market caution regarding its long-term potential.
Newsfilter
9.5
05-05Newsfilter
Tovecimig Shows Significant Survival Benefit in Biliary Tract Cancer Trial
  • Clinical Trial Results: In a Phase 2/3 study of biliary tract cancer patients, the combination of tovecimig and paclitaxel demonstrated a progression-free survival (PFS) of 4.7 months, significantly better than the 2.6 months for paclitaxel alone (HR=0.44, p<0.0001), indicating tovecimig's potential as a new second-line treatment option.
  • FDA Meeting Planned: Tovecimig received Orphan Drug Designation in April 2026, and the company plans to meet with the FDA prior to its Biologics License Application (BLA) submission, paving the way for market access to address the urgent needs of biliary tract cancer patients.
  • Financial Position: As of Q1 2026, the company reported $195 million in cash and marketable securities, expected to fund operations into 2028, although this reflects a decrease from $209 million at the end of 2025, highlighting ongoing investments in R&D.
  • R&D Progress: Clinical trials for CTX-8371 and CTX-10726 are underway, with the former showing deep responses in three cancer types and initial data from the latter expected in Q4 2026, further enhancing the company's competitive edge in oncology therapeutics.
PRnewswire
7.0
04-30PRnewswire
Pomerantz LLP Investigates Compass Therapeutics for Securities Fraud
  • Securities Fraud Investigation: Pomerantz LLP is investigating Compass Therapeutics for potential securities fraud or unlawful business practices by its officers, which could undermine investor confidence and lead to legal repercussions.
  • Clinical Trial Results: On April 27, 2026, Compass announced that its drug tovecimig met the key secondary endpoint of progression-free survival in a phase 2/3 study for biliary tract cancer treatment, but failed to meet the overall survival endpoint, indicating mixed results.
  • Stock Price Plunge: Following this announcement, Compass's stock price fell by $3.24, or 64.41%, closing at $1.79 per share on April 27, 2026, reflecting market disappointment over the clinical trial outcomes.
  • Potential Legal Consequences: The investigation by Pomerantz LLP, a prominent firm in securities class action litigation, may lead to class action lawsuits against Compass, exacerbating the company's trust crisis among investors and impacting its future financing and market performance.
NASDAQ.COM
8.5
04-30NASDAQ.COM
Latest Developments in the Biotech Sector
  • Regulatory Approvals: Crinetics received European Commission approval for PALSONIFY to treat acromegaly in adults, becoming the first once-daily oral therapy in Europe, covering 27 EU member states, which is expected to significantly enhance market share.
  • Acquisition Expansion: Teva is acquiring Emalex Biosciences for $700 million, bolstering its neuroscience pipeline and potentially accelerating the NDA submission for Ecopipam, thereby strengthening Teva's competitive position in the CNS disorders market.
  • Clinical Trial Progress: Biomea Fusion's Icovamenib showed a 52% increase in mean C-peptide AUC in its Phase 2 trial for Type 1 Diabetes, indicating potential efficacy in early-stage patients, which may drive further development efforts.
  • Market Reactions: Despite multiple approvals, AstraZeneca and Novartis saw their stock prices decline by 0.79% and 1.76% respectively, reflecting a cautious investor sentiment towards the biotech sector.
Yahoo Finance
4.5
04-28Yahoo Finance
U.S. Stocks Decline Amid Geopolitical Tensions and Earnings Strength
  • Geopolitical Tensions: Stalled peace negotiations between the U.S. and Iran have led to rising oil prices, raising fresh concerns about inflation and global economic growth, as investors balance strong corporate earnings against geopolitical uncertainties.
  • Earnings Performance: Verizon (VZ) reported a better-than-expected Q1, while Domino's Pizza (DPZ) posted disappointing results and announced an additional $1 billion share repurchase program, highlighting the varied market reactions to different companies.
  • Acquisition Activity: Shell (SHEL) agreed to acquire ARC Resources (AETUF) for C$32.80 per share, while China blocked Meta's (META) acquisition of AI startup Manus, reflecting the complexities of the global M&A landscape.
  • Market Index Fluctuations: Near midday, the Dow was down 0.25%, the Nasdaq down 0.28%, and the S&P 500 down 0.14%, indicating the market's sensitive response to geopolitical tensions and economic data.
seekingalpha
9.0
04-27seekingalpha
Compass Therapeutics Shares Plunge 66% After Clinical Trial Setback
  • Clinical Trial Setback: Compass Therapeutics' biliary tract cancer candidate tovecimig missed a key secondary endpoint—overall survival—in a phase 2/3 study, resulting in a ~66% drop in stock price on Monday.
  • Crossover Patient Impact: The COMPANION-002 study showed 54% of patients crossed over to the treatment group, complicating results; crossover patients had a median overall survival of 12.8 months compared to 6.1 months for non-crossover patients, indicating data complexity.
  • Secondary Endpoint Achieved: While overall survival was not met, the combination of tovecimig and paclitaxel achieved a median progression-free survival of 4.7 months versus 2.6 months for placebo, indicating some efficacy.
  • Financial Performance: Compass Therapeutics reported a GAAP EPS of -$0.09, reflecting financial pressure from R&D and clinical trials, suggesting investors need to exercise patience for potential future opportunities.
Wall Street analysts forecast CMPX stock price to rise
8 Analyst Rating
Wall Street analysts forecast CMPX stock price to rise
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
8.00
Averages
12.67
High
24.00
Current: 0.000
sliders
Low
8.00
Averages
12.67
High
24.00
Raymond James
Sean McCutcheon
Outperform -> Market Perform
downgrade
$NULL
AI Analysis
2026-04-28
Reason
Raymond James
Sean McCutcheon
Price Target
$NULL
AI Analysis
2026-04-28
downgrade
Outperform -> Market Perform
Reason
Raymond James analyst Sean McCutcheon downgraded Compass Therapeutics to Market Perform from Outperform with no price target after Compass disclosed survival outcomes from COMPANION-002, the Phase 3 trial of tovecimig in combination with paclitaxel for the treatment of second line biliary tract cancer. The dataset \"sits within the true bear scenario from our preview of the readout,\" says the analyst, whose confidence in the approval and a potential commercialization of tovecimig in 2L BTC is reduced.
Canaccord
Buy
downgrade
$13 -> $7
2026-04-28
Reason
Canaccord
Price Target
$13 -> $7
2026-04-28
downgrade
Buy
Reason
Canaccord lowered the firm's price target on Compass Therapeutics to $7 from $13 and keeps a Buy rating on the shares. The firm said Tovecimig+paclitaxel clearly improves progression-free survival vs paclitaxel monotherapy, but 54% crossover confounded any possible overall survival benefit in the ITT population. The active arm did however show numerically superior overall survival to patients that did not crossover, but they doubt the FDA would consider this to be sufficient for full approval.
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Valuation Metrics

The current forward P/E ratio for Compass Therapeutics Inc. (CMPX.O) is 0.00, compared to its 5-year average forward P/E of -6.38. For a more detailed relative valuation and DCF analysis to assess Compass Therapeutics Inc.'s fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.38
Current PE
0.00
Overvalued PE
-3.58
Undervalued PE
-9.19

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.40
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-0.59
Undervalued EV/EBITDA
-6.21

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
19.73
Current PS
10.59
Overvalued PS
146.06
Undervalued PS
-106.61

Financials

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Whales Holding CMPX

S
Suvretta Capital Management, LLC
Holding
CMPX
+13.24%
3M Return
D
Deerfield Management Company, L.P.
Holding
CMPX
+8.87%
3M Return
B
BVF Partners L.P.
Holding
CMPX
+7.71%
3M Return
T
Tang Capital Management, LLC
Holding
CMPX
+3.72%
3M Return
S
Sofinnova Investment, Inc.
Holding
CMPX
+1.88%
3M Return
R
Rock Springs Capital Management LP
Holding
CMPX
+1.39%
3M Return

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Frequently Asked Questions

What is Compass Therapeutics Inc. (CMPX) stock price today?

The current price of CMPX is 1.845 USD — it has increased 0.82

What is Compass Therapeutics Inc. (CMPX)'s business?

Compass Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company. The Company is developing proprietary antibody-based therapeutics to treat multiple human diseases. Its pipeline of novel product candidates is designed to target multiple critical biological pathways required for an effective anti-tumor response. Its lead product candidate, tovecimig, is a bispecific antibody targeting Delta-like ligand 4 (DLL4), a ligand of Notch-1, and vascular endothelial growth factor A (VEGF-A). Its second program, CTX-471, is an agonistic antibody targeting a member of the tumor necrosis factor receptor superfamily member 9 (TNFRSF9), also known as CD-137, a co-stimulatory receptor which is mostly expressed on activated, but not on resting T-cells and NK cells. Its third program, CTX-8371, is a bispecific antibody targeting the programmed cell death protein-1 (PD-1), an inhibitory immune checkpoint receptor, and its ligand PD-L1, two validated immune-oncology targets.

What is the price predicton of CMPX Stock?

Wall Street analysts forecast CMPX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CMPX is12.67 USD with a low forecast of 8.00 USD and a high forecast of 24.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Compass Therapeutics Inc. (CMPX)'s revenue for the last quarter?

Compass Therapeutics Inc. revenue for the last quarter amounts to 0.00 USD, decreased

What is Compass Therapeutics Inc. (CMPX)'s earnings per share (EPS) for the last quarter?

Compass Therapeutics Inc.. EPS for the last quarter amounts to -0.10 USD, decreased -16.67

How many employees does Compass Therapeutics Inc. (CMPX). have?

Compass Therapeutics Inc. (CMPX) has 39 emplpoyees as of May 11 2026.

What is Compass Therapeutics Inc. (CMPX) market cap?

Today CMPX has the market capitalization of 329.56M USD.