Boundless Bio Announces Portfolio Prioritization and Runway Extension
Portfolio Updates: Boundless Bio is prioritizing the combination therapy of BBI-355 and BBI-825 while discontinuing current arms of the POTENTIATE clinical trial. The company has also declared BBI-940 as a development candidate for its novel Kinesin program, with plans to submit an IND application in early 2026.
Operational Changes: The company's operational streamlining, including a workforce reduction, aims to extend its cash runway into the first half of 2028, allowing time to achieve proof-of-concept clinical milestones for its therapeutic programs.
Trade with 70% Backtested Accuracy
Analyst Views on BOLD
About BOLD
About the author
Boundless Bio Reports Second Quarter 2025 Financial Results and Business Highlights
POTENTIATE Trial Enrollment: Boundless Bio has opened enrollment for the BBI-355 and BBI-825 combination arm of the POTENTIATE trial, expecting to deliver initial proof-of-concept clinical data within its cash runway timeline.
Financial Overview: The company reported a net loss of $15.7 million for Q2 2025, with $127 million in cash supporting operations through expected clinical readouts into 2028.
Rice Biotech Launch Pad welcomes Carolyn Ng to external advisory board
Appointment of Carolyn Ng: Carolyn Ng has been appointed to the external advisory board of the Rice Biotech Launch Pad, bringing her extensive experience in biotech and company building to support the accelerator's mission of translating health and medical technology discoveries into effective therapies.
Role of the Rice Biotech Launch Pad: The Rice Biotech Launch Pad aims to expedite the transition of innovative research from Rice University into clinical studies and commercialization, contributing to Houston's growth as a leading biotech hub.