BioNTech and Bristol Myers Squibb Announce Lung Cancer Trial Data
Written by Emily J. Thompson, Senior Investment Analyst
Updated: May 31 2026
0mins
BioNTech SE (BNTX) and Bristol Myers Squibb Company (BMS) announced interim Phase 2 data from the global Phase 2/3 ROSETTA Lung-02 clinical trial evaluating the investigational PD-L1xVEGF-A bispecific immunomodulator pumitamig plus chemotherapy in patients with previously untreated advanced non-small cell lung cancer, NSCLC. Key highlights include: First investigational PD-(L)1xVEGF bispecific immunomodulator to present global data showing encouraging efficacy in combination with chemotherapy in first-line non-small cell lung cancer across PD-L1 expression levels and subtypes, highlighting its potential to set a new standard of care; Pumitamig plus chemotherapy showed robust and consistent antitumor activity in first-line non-small cell lung cancer at both evaluated dose levels, with higher confirmed objective response rates at the lower dose of 63.6% in the non-squamous and 72.7% in the squamous subtypes; Pumitamig is advancing through a comprehensive global Phase 3 development program in non-small cell lung cancer, including the actively enrolling pivotal Phase 3 part of the ROSETTA Lung-02 trial, along with two additional global Phase 3 trials
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Analyst Views on BNTX
Wall Street analysts forecast BNTX stock price to rise
13 Analyst Rating
12 Buy
1 Hold
0 Sell
Strong Buy
Current: 92.220
Low
113.00
Averages
143.17
High
181.00
Current: 92.220
Low
113.00
Averages
143.17
High
181.00
About BNTX
BioNTech SE is a Germany-based clinical-stage biotechnology company. The Company focuses on patient-specific immunotherapies for the treatment of cancer and other serious diseases. The Company is providing technologies including mRNA-based therapies, cell therapies, small molecules and antibodies, which can be utilized for specific purposes or can be even combined with each other in a synergistic manner. It also develops a broad product pipeline using different scientific approaches and technology platforms, including individualized mRNA-based product candidates, chimeric antigen receptor T-cells, checkpoint immunomodulators, targeted cancer antibodies and small molecules. In addition, the Company offers diagnostic products and drug discovery services for other therapeutic areas, including infectious diseases, allergies and autoimmune disorders.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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See More
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- Future Development Plans: BioNTech and Bristol Myers Squibb are advancing a broad development plan for Pumitamig, aiming to evaluate its efficacy in various stages of non-small cell lung cancer across multiple clinical trials, with the goal of improving existing treatment standards.
See More
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See More
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- Pipeline Advancement: BioNTech is advancing over 25 Phase 2 and Phase 3 clinical trials, including 13 pivotal trials, showcasing the company's robust R&D capabilities and commitment to innovative treatment solutions in oncology.
- ASCO 2026 Presentation: BioNTech will present new clinical data from its late-stage oncology programs at the 2026 American Society of Clinical Oncology Annual Meeting, emphasizing its strategy to deliver differentiated therapies across various tumor types, thereby strengthening its market position.
See More
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- Board Expansion: Shareholders approved the expansion of the Supervisory Board from six to eight members, adding expertise from Prof. Iris Löw-Friedrich and Dr. Susanne Schaffert, aimed at strengthening the company's capabilities in oncology treatment.
- Current Board Members' Mandate Extension: The extension of mandates for Helmut Jeggle, Prof. Anja Morawietz, and Prof. Rudolf Staudigl was also approved, ensuring experience and stability in key decision-making processes, which further drives the achievement of the company's strategic objectives.
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