Silo Pharma Completes $2.5 Million Registered Direct Offering at Market Price in Compliance with Nasdaq Regulations
Silo Pharma's Offering: Silo Pharma, Inc. has closed a registered direct offering of 2,857,143 shares of common stock at $0.875 per share, raising approximately $2.5 million for working capital and corporate purposes.
Warrants Issued: In a concurrent private placement, the company issued unregistered warrants to purchase an equal number of shares at an exercise price of $0.75, which are immediately exercisable and will expire in five years.
Regulatory Compliance: The common stock was offered under an effective registration statement with the SEC, while the unregistered warrants were offered in a private placement and are not registered under the Securities Act.
Company Focus: Silo Pharma is a developmental-stage biopharmaceutical company targeting underserved conditions such as PTSD and chronic pain, with research collaborations with leading universities and laboratories.
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Silo Pharma Partners with Allucent to Advance SPC-15 Clinical Studies
- Clinical Research Collaboration: Silo Pharma has signed a Letter of Intent with global CRO Allucent to conduct two Phase 1 studies for its SPC-15 nasal spray, marking a significant advancement in the treatment of psychiatric disorders.
- Study Design Details: The studies will include an Open-Label Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD) design, aimed at efficiently generating safety and pharmacokinetic data to expedite SPC-15's clinical development.
- Strategic Importance: CEO Eric Weisblum stated that this collaboration will enhance the rigor and speed of the research, further advancing SPC-15's development to provide new therapies for PTSD and anxiety patients.
- Product Background: SPC-15 is an investigational intranasal 5-HT4 receptor agonist designed for rapid brain action using a special soft mist delivery system, with plans to leverage biomarkers for an accelerated FDA approval pathway.

Silo Pharma Enters LOI with Allucent for SPC-15 Clinical Studies
- Clinical Research Collaboration: Silo Pharma has signed a Letter of Intent with global CRO Allucent to conduct two Phase 1 studies for its SPC-15 nasal spray, marking a significant advancement in the treatment of PTSD and anxiety.
- Agreement Details: The LOI outlines comprehensive support for clinical operations, pharmacovigilance, and data management, which is expected to accelerate the clinical development of SPC-15, enhancing the company's competitiveness in the biopharmaceutical sector.
- Drug Development Context: SPC-15 is an investigational intranasal 5-HT4 receptor agonist targeting stress-induced psychiatric conditions, aiming for rapid brain action to alleviate PTSD and anxiety symptoms, indicating its potential market value.
- Long-term Value Creation: The CEO of Silo Pharma stated that this collaboration will facilitate the efficient generation of safety and pharmacokinetic data, further driving innovation and long-term growth in the mental health space.









