Affinity Asset Advisors Acquires New Stake in Praxis Precision Medicines
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 4 days ago
0mins
Should l Buy PRAX?
Source: Fool
- New Investment Disclosure: On February 13, 2026, Affinity Asset Advisors disclosed a new position by acquiring 185,000 shares of Praxis Precision Medicines in an estimated $54.53 million trade, indicating strong confidence in the company's future potential.
- Significant Stake: This acquisition accounts for 3.11% of Affinity's reportable assets in its 13F filing, reflecting the fund's keen interest in the biotech sector and diversification of its investment portfolio.
- Outstanding Stock Performance: As of February 13, 2026, Praxis shares were priced at $317.25, up 266.1% over the past year, significantly outperforming the S&P 500 by 254.29 percentage points, showcasing strong market recognition of its clinical pipeline.
- Increased R&D Spending: Praxis reported a third-quarter R&D expense of $65.8 million, with a net loss widening to $73.9 million; however, its multiple late-stage projects provide several commercialization opportunities, highlighting the company's potential in drug development.
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Analyst Views on PRAX
Wall Street analysts forecast PRAX stock price to rise
15 Analyst Rating
14 Buy
0 Hold
1 Sell
Strong Buy
Current: 328.040
Low
95.00
Averages
456.71
High
843.00
Current: 328.040
Low
95.00
Averages
456.71
High
843.00
About PRAX
Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. The Company is applying genetic insights to the discovery and development of therapies for neurological disorders through two platforms, using its understanding of shared biological targets and circuits in the brain. Its platform includes Cerebrum, a small-molecule platform, which utilizes deep understanding of neuronal excitability and neuronal networks and applies a series of computational and experimental tools to develop orally available precision therapies, and Solidus, an antisense oligonucleotide platform, is an efficient, targeted precision medicine discovery and development engine anchored on a proprietary, computational methodology. The Company’s product candidates include ulixacaltamide, vormatrigine, relutrigine, PRAX-080, and others.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Earnings Announcement Schedule: Praxis Precision Medicines is set to release its Q4 earnings on February 19 before market open, with consensus EPS estimate at -$3.13 and revenue estimate at $0.26M, indicating challenges in profitability.
- Earnings Estimate Changes: Over the past three months, EPS estimates have seen three upward revisions and two downward adjustments, reflecting analysts' mixed views on the company's future performance, which may impact investor confidence.
- Stock Offering Plan: Praxis Precision Medicines has announced a proposed public stock offering of $575 million at a price of $260 per share, aimed at funding future research and operations, although this may dilute existing shareholders' stakes.
- Market Reaction Anticipation: With the upcoming earnings report and stock offering plan, market attention on Praxis is increasing, and investors should closely monitor the earnings results and their implications for the company's future strategy.
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- Stake Increase: Cormorant Asset Management disclosed on Tuesday that it has increased its stake in MoonLake Immunotherapeutics to 4.36 million shares, representing a 6.1% ownership, up from about 2 million shares in October 2025, indicating strong confidence in the company's future and potential stock price impact.
- Significant Stock Surge: Following the news of Cormorant's increased stake, MoonLake's shares jumped 11% on Tuesday, marking the largest rally in over a month, reflecting heightened market interest in a possible takeover and potentially attracting more investors.
- Market Sentiment Shift: Retail sentiment for MLTX on Stocktwits flipped from 'extremely bearish' to 'extremely bullish' with a 900% surge in message volume over 24 hours, indicating strong investor expectations for the company's future, which could further drive stock price increases.
- FDA Fast Track Progress: MoonLake's Sonelokimab received FDA Fast Track designation, with plans to pursue a biologics license application in the second half of 2026, highlighting the company's potential in the treatment space and likely drawing increased institutional investor interest in its long-term growth prospects.
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- New Investment Disclosure: On February 13, 2026, Affinity Asset Advisors disclosed a new position by acquiring 185,000 shares of Praxis Precision Medicines in an estimated $54.53 million trade, indicating strong confidence in the company's future potential.
- Significant Stake: This acquisition accounts for 3.11% of Affinity's reportable assets in its 13F filing, reflecting the fund's keen interest in the biotech sector and diversification of its investment portfolio.
- Outstanding Stock Performance: As of February 13, 2026, Praxis shares were priced at $317.25, up 266.1% over the past year, significantly outperforming the S&P 500 by 254.29 percentage points, showcasing strong market recognition of its clinical pipeline.
- Increased R&D Spending: Praxis reported a third-quarter R&D expense of $65.8 million, with a net loss widening to $73.9 million; however, its multiple late-stage projects provide several commercialization opportunities, highlighting the company's potential in drug development.
See More
- New Investment Disclosure: Affinity Asset Advisors disclosed a new position in PRAX, acquiring 185,000 shares valued at approximately $54.53 million in Q4 2026, indicating confidence in the company's future prospects.
- Asset Allocation Insight: This acquisition positions PRAX to represent 3.11% of Affinity's reportable 13F assets, highlighting its significance within the portfolio despite not being among the top five holdings.
- R&D Progress: Praxis Precision Medicines is at a pivotal moment, expecting to submit two new drug applications by mid-February, with the CEO noting that both drugs have shown compelling late-stage results and received Breakthrough Therapy Designation, potentially driving future growth.
- Financial Overview: Praxis reported approximately $956 million in cash and investments, expected to fund operations into 2028, although R&D expenses rose to $65.8 million and net losses widened to $73.9 million, the advancement of multiple clinical programs lays a foundation for future commercialization.
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- Share Increase: Soleus Capital Management disclosed a purchase of 629,398 shares of Celcuity in an SEC filing, raising its total holdings to over 1.8 million shares valued at $180.36 million, indicating strong confidence in the company.
- Asset Allocation Shift: Celcuity now accounts for 6.7% of Soleus Capital's AUM, becoming its third-largest holding among 95 positions, reflecting investor interest in the biotechnology sector.
- Stock Performance: Celcuity's stock price surged 745% over the past year, significantly outperforming the S&P 500's 14.4% and NASDAQ Composite's 15.7%, highlighting strong market expectations for its future potential.
- Risk Advisory: Despite Celcuity's impressive stock performance, the company currently generates no revenue, necessitating caution from investors regarding inherent risks, as the stock's value is heavily reliant on drug approvals and future profitability prospects.
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- Earnings Report Schedule: Praxis Precision Medicines is set to announce its Q4 and full year 2025 financial results on February 19, 2026, before the market opens, which is expected to impact investor confidence positively.
- Conference Call Details: The company will host a conference call and live webcast at 8:00 AM ET on February 19, 2026, to review financial results in detail, enhancing transparency and attracting investor attention.
- Investor Conference Participation: Praxis will present at the Guggenheim Emerging Outlook: Biotech Summit 2026 on February 11 in New York City, further elevating its profile in the biotechnology sector.
- Upcoming Event Schedule: The company will also participate in the TD Cowen 46th Annual Health Care Conference on March 2, showcasing its diversified CNS product portfolio, which is expected to draw more investor interest.
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