Structure Therapeutics Inc Hits 52-Week High on Positive Trial Data
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 08 Dec 25
Source: SeekingAlpha
Structure Therapeutics Inc's stock surged by 36.00%, reaching a 52-week high following the announcement of positive Phase 2b results for aleniglipron.
In the recent ACCESS study, aleniglipron demonstrated a significant placebo-adjusted weight loss of 15.3% at the 240 mg dose, indicating its potential as a leading treatment for obesity. The company plans to advance to Phase 3 trials, further solidifying its position in the biopharmaceutical market.
The promising results not only enhance investor confidence but also highlight the growing market potential for innovative obesity treatments. With the global obesity crisis worsening, aleniglipron's success could reshape the treatment landscape and meet significant unmet medical needs.
Analyst Views on GPCR
Wall Street analysts forecast GPCR stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for GPCR is 104.00 USD with a low forecast of 65.00 USD and a high forecast of 130.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
13 Analyst Rating
13 Buy
0 Hold
0 Sell
Strong Buy
Current: 89.050
Low
65.00
Averages
104.00
High
130.00
Current: 89.050
Low
65.00
Averages
104.00
High
130.00
About GPCR
Structure Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing oral small molecule treatments for chronic metabolic and cardiopulmonary conditions with significant unmet medical needs. Its programs include Aleniglipron (GSBR-1290), ACCG-2671, GIP and GCG Receptor Oral Small Molecule Obesity Programs, ANPA-0073, and LTSE-2578. Its Aleniglipron is an oral and biased small molecule agonist of GLP-1R, a validated GPCR drug target for obesity. ACCG-2671 is an oral small molecule amylin receptor agonist for obesity. ANPA-0073 is a biased agonist targeting the apelin (APJ) receptor agonist. Its LTSE-2578, an Oral Small Molecule LPA1R Antagonist for IPF. It is developing an antagonist that targets lysophosphatidic acid 1 receptor (LPA1R), a GPCR implicated in responses to tissue injury and pro-fibrotic processes, for the treatment of IPF. It is developing oral incretins for potential combination therapy with GLP-1R or amylin candidates.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.





