CRISPR Therapeutics Gains on Casgevy Approval and Strong Pipeline
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jun 19 2025
0mins
Source: NASDAQ.COM
CRISPR Therapeutics AG's stock rose by 4.99% as it reached a 20-day high, reflecting positive momentum in the gene editing sector.
The company received approval for Casgevy, a treatment for sickle cell disease and transfusion-dependent beta-thalassemia, which is expected to see significant commercial growth despite currently low revenue. Additionally, CRISPR's CTX310, aimed at lowering LDL cholesterol, enhances its competitive position in the market, contributing to investor confidence.
With $2.4 billion in cash, CRISPR Therapeutics is well-positioned to navigate clinical trial challenges, making it an attractive investment choice in the gene editing space.
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Analyst Views on CRSP
Wall Street analysts forecast CRSP stock price to rise
10 Analyst Rating
8 Buy
2 Hold
0 Sell
Strong Buy
Current: 56.380
Low
50.00
Averages
78.89
High
105.00
Current: 56.380
Low
50.00
Averages
78.89
High
105.00
About CRSP
CRISPR Therapeutics AG is a Switzerland-based gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) and is a technology for gene editing, the process of precisely altering specific sequences of genomic DNA. The Company aims to apply this technology to disrupt, delete, correct and insert genes to treat genetically-defined diseases and to engineer advanced cellular therapies. The Company has acquired the rights to the intellectual property (IP) encompassing CRISPR/Cas9 and related technologies and is also involved in its own IP research and additional in-licensing efforts. The Company product development and partnership strategies are designed to exploit the full potential of the CRISPR/Cas9 platform while maximizing the probability of successfully developing their product candidates.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Gene Editing Sector Gains Momentum with Key Players CRISPR and Beam
- CRISPR Therapeutics Progress: In 2023, CRISPR Therapeutics received approval for Casgevy, a treatment for sickle cell disease and transfusion-dependent beta-thalassemia, which, despite currently low revenue, is expected to see significant commercial growth in the coming years.
- Pipeline Advantage: CRISPR Therapeutics boasts a deeper pipeline, including CTX310 aimed at lowering LDL cholesterol, offering a potential one-time treatment option that could enhance its market competitiveness and stock price.
- Beam Therapeutics Innovation: Beam Therapeutics focuses on base editing technology and, while lacking marketed products, has shown strong results with its clinical candidate Risto-cel, with plans to submit a regulatory application by year-end, potentially driving stock price increases.
- Financial Comparison: As of the end of Q1, CRISPR Therapeutics held $2.4 billion in cash and equivalents compared to Beam Therapeutics' $1.2 billion, providing CRISPR with greater resilience against clinical trial setbacks, making it a more attractive investment choice.
See More
Analysis of Gene Editing Industry Prospects
- CRISPR Breakthrough: CRISPR Therapeutics received approval for Casgevy in 2023, a treatment for sickle cell disease and transfusion-dependent beta-thalassemia, which, despite currently low revenue, is expected to see significant commercial growth in the coming years.
- Pipeline Advantage: The company's CTX310 is being developed to lower LDL cholesterol as a potential one-time treatment option, which could provide a more convenient choice in cardiovascular disease management, thereby enhancing its competitive position in the market.
- Beam Innovation: Beam Therapeutics focuses on base editing technology and, while it currently has no products on the market, its Risto-cel candidate has shown strong results in clinical trials, with plans to submit a regulatory application by year-end, potentially driving its stock price higher.
- Financial Comparison: As of the end of Q1, CRISPR Therapeutics had $2.4 billion in cash and marketable securities compared to Beam Therapeutics' $1.2 billion, indicating stronger financial stability that provides better resilience against clinical trial setbacks.
See More
2026 Investment Strategy: Focus on Quality Stocks
- Roku Market Share Growth: Roku's share of the North American connected TV market has reached 36%, nearly double that of Amazon, and despite stagnation in the streaming industry, Roku's platform revenue grew by 28% year-over-year, demonstrating its strong profitability in digital entertainment sales.
- ServiceNow Long-Term Growth Potential: With a market cap of $107 billion, ServiceNow is projected to grow its revenue from $13.3 billion in 2025 to $29.5 billion by 2030, reflecting an annualized growth rate of nearly 25%, indicating its sustained leadership in the workflow automation sector.
- CRISPR Therapeutics Market Outlook: CRISPR Therapeutics' gene therapy Casgevy has received FDA approval, with sales expected to reach $40 million this year and potentially double next year, highlighting its significant potential in the gene editing market despite high costs and complex treatment processes.
- Investor Sentiment Shift: The volatile start to 2026 has left many investors uncertain; however, maintaining a focus on quality stocks as a long-term investment strategy remains the best approach to avoid missteps caused by short-term market fluctuations.
See More
CRISPR Therapeutics Shows Promising Upside Potential
- Strong Stock Performance: CRISPR Therapeutics' shares have surged 56% over the past year, significantly outperforming the S&P 500's 30% gain, indicating robust market confidence in its growth prospects.
- Optimistic Analyst Targets: According to Yahoo! Finance, CRISPR's average price target is $82.55, suggesting nearly 51% upside from current levels, while Piper Sandler's analyst has set a target of $110, indicating the stock could potentially double in the next 12 months.
- Catalysts from Clinical Trials: The ongoing development of the anticoagulant CTX611 could yield crucial clinical trial data in the coming months, targeting a $20 billion market, and positive results could significantly boost the stock price.
- Market Expansion Potential: The Casgevy drug, developed in collaboration with Vertex Pharmaceuticals, has yet to generate significant sales despite its 2023 approval due to its complex administration and high cost; however, the recent request for approval for children aged 5 to 11 could greatly expand its market potential, with annual revenues expected to exceed $1 billion in the coming years.
See More
Vertex Pharmaceuticals: Investment Returns and Future Outlook
- Significant Investment Returns: An investment of $20,000 in Vertex Pharmaceuticals during its 1991 IPO would now exceed $1 million, reflecting a commendable 14% compound annual growth rate, which outperforms the S&P 500's 11% over the same period, indicating the company's robust long-term growth potential.
- Core Market Dominance: Vertex Pharmaceuticals leads the cystic fibrosis (CF) market, treating approximately 95% of CF patients in the U.S., although its revenue growth has slowed, with an 8% year-over-year increase to $2.99 billion in Q1, suggesting sustained market demand despite challenges.
- Diversification Challenges: While Vertex aims to reduce its reliance on CF, it anticipates $500 million in non-CF revenue this year, a significant increase from $10 million in 2024, yet this growth remains insufficient, highlighting ongoing challenges in its diversification efforts.
- Future Growth Potential: Vertex is seeking approval for Casgevy, a gene-editing drug for sickle cell disease and transfusion-dependent beta-thalassemia, which could drive future growth, alongside advancing povetacicept for IgA nephropathy, showcasing the potential for an expanded product portfolio.
See More
Vertex Pharmaceuticals' Future Outlook Appears Promising
- Core Business Slowdown: Vertex Pharmaceuticals reported an 8% year-over-year revenue increase to $2.99 billion in Q1, which, while not terrible, reflects a general downward trend in growth over recent years, indicating weakness in its core market.
- Non-CF Revenue Potential: The company expects at least $500 million in non-CF revenue for 2023, a significant increase from $10 million in 2024, suggesting that its diversification efforts are beginning to pay off.
- New Drug Development Progress: Vertex is seeking approval for Casgevy, a gene-editing medicine for sickle cell disease and transfusion-dependent beta-thalassemia, aimed at providing early treatment for patients aged 5 to 11, highlighting its significant market potential.
- Future Growth Outlook: As Vertex continues to develop new products in the CF space and expand its portfolio, it is expected to achieve stronger revenue and earnings growth in the coming years, presenting a positive long-term outlook.
See More
Gene Editing Sector Gains Momentum with Key Players CRISPR and Beam
- CRISPR Therapeutics Progress: In 2023, CRISPR Therapeutics received approval for Casgevy, a treatment for sickle cell disease and transfusion-dependent beta-thalassemia, which, despite currently low revenue, is expected to see significant commercial growth in the coming years.
- Pipeline Advantage: CRISPR Therapeutics boasts a deeper pipeline, including CTX310 aimed at lowering LDL cholesterol, offering a potential one-time treatment option that could enhance its market competitiveness and stock price.
- Beam Therapeutics Innovation: Beam Therapeutics focuses on base editing technology and, while lacking marketed products, has shown strong results with its clinical candidate Risto-cel, with plans to submit a regulatory application by year-end, potentially driving stock price increases.
- Financial Comparison: As of the end of Q1, CRISPR Therapeutics held $2.4 billion in cash and equivalents compared to Beam Therapeutics' $1.2 billion, providing CRISPR with greater resilience against clinical trial setbacks, making it a more attractive investment choice.
See More
Analysis of Gene Editing Industry Prospects
- CRISPR Breakthrough: CRISPR Therapeutics received approval for Casgevy in 2023, a treatment for sickle cell disease and transfusion-dependent beta-thalassemia, which, despite currently low revenue, is expected to see significant commercial growth in the coming years.
- Pipeline Advantage: The company's CTX310 is being developed to lower LDL cholesterol as a potential one-time treatment option, which could provide a more convenient choice in cardiovascular disease management, thereby enhancing its competitive position in the market.
- Beam Innovation: Beam Therapeutics focuses on base editing technology and, while it currently has no products on the market, its Risto-cel candidate has shown strong results in clinical trials, with plans to submit a regulatory application by year-end, potentially driving its stock price higher.
- Financial Comparison: As of the end of Q1, CRISPR Therapeutics had $2.4 billion in cash and marketable securities compared to Beam Therapeutics' $1.2 billion, indicating stronger financial stability that provides better resilience against clinical trial setbacks.
See More
2026 Investment Strategy: Focus on Quality Stocks
- Roku Market Share Growth: Roku's share of the North American connected TV market has reached 36%, nearly double that of Amazon, and despite stagnation in the streaming industry, Roku's platform revenue grew by 28% year-over-year, demonstrating its strong profitability in digital entertainment sales.
- ServiceNow Long-Term Growth Potential: With a market cap of $107 billion, ServiceNow is projected to grow its revenue from $13.3 billion in 2025 to $29.5 billion by 2030, reflecting an annualized growth rate of nearly 25%, indicating its sustained leadership in the workflow automation sector.
- CRISPR Therapeutics Market Outlook: CRISPR Therapeutics' gene therapy Casgevy has received FDA approval, with sales expected to reach $40 million this year and potentially double next year, highlighting its significant potential in the gene editing market despite high costs and complex treatment processes.
- Investor Sentiment Shift: The volatile start to 2026 has left many investors uncertain; however, maintaining a focus on quality stocks as a long-term investment strategy remains the best approach to avoid missteps caused by short-term market fluctuations.
See More
CRISPR Therapeutics Shows Promising Upside Potential
- Strong Stock Performance: CRISPR Therapeutics' shares have surged 56% over the past year, significantly outperforming the S&P 500's 30% gain, indicating robust market confidence in its growth prospects.
- Optimistic Analyst Targets: According to Yahoo! Finance, CRISPR's average price target is $82.55, suggesting nearly 51% upside from current levels, while Piper Sandler's analyst has set a target of $110, indicating the stock could potentially double in the next 12 months.
- Catalysts from Clinical Trials: The ongoing development of the anticoagulant CTX611 could yield crucial clinical trial data in the coming months, targeting a $20 billion market, and positive results could significantly boost the stock price.
- Market Expansion Potential: The Casgevy drug, developed in collaboration with Vertex Pharmaceuticals, has yet to generate significant sales despite its 2023 approval due to its complex administration and high cost; however, the recent request for approval for children aged 5 to 11 could greatly expand its market potential, with annual revenues expected to exceed $1 billion in the coming years.
See More
Vertex Pharmaceuticals: Investment Returns and Future Outlook
- Significant Investment Returns: An investment of $20,000 in Vertex Pharmaceuticals during its 1991 IPO would now exceed $1 million, reflecting a commendable 14% compound annual growth rate, which outperforms the S&P 500's 11% over the same period, indicating the company's robust long-term growth potential.
- Core Market Dominance: Vertex Pharmaceuticals leads the cystic fibrosis (CF) market, treating approximately 95% of CF patients in the U.S., although its revenue growth has slowed, with an 8% year-over-year increase to $2.99 billion in Q1, suggesting sustained market demand despite challenges.
- Diversification Challenges: While Vertex aims to reduce its reliance on CF, it anticipates $500 million in non-CF revenue this year, a significant increase from $10 million in 2024, yet this growth remains insufficient, highlighting ongoing challenges in its diversification efforts.
- Future Growth Potential: Vertex is seeking approval for Casgevy, a gene-editing drug for sickle cell disease and transfusion-dependent beta-thalassemia, which could drive future growth, alongside advancing povetacicept for IgA nephropathy, showcasing the potential for an expanded product portfolio.
See More
Vertex Pharmaceuticals' Future Outlook Appears Promising
- Core Business Slowdown: Vertex Pharmaceuticals reported an 8% year-over-year revenue increase to $2.99 billion in Q1, which, while not terrible, reflects a general downward trend in growth over recent years, indicating weakness in its core market.
- Non-CF Revenue Potential: The company expects at least $500 million in non-CF revenue for 2023, a significant increase from $10 million in 2024, suggesting that its diversification efforts are beginning to pay off.
- New Drug Development Progress: Vertex is seeking approval for Casgevy, a gene-editing medicine for sickle cell disease and transfusion-dependent beta-thalassemia, aimed at providing early treatment for patients aged 5 to 11, highlighting its significant market potential.
- Future Growth Outlook: As Vertex continues to develop new products in the CF space and expand its portfolio, it is expected to achieve stronger revenue and earnings growth in the coming years, presenting a positive long-term outlook.
See More
