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CRSP Should I Buy

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Intellectia

Should You Buy CRISPR Therapeutics AG (CRSP) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
52.200
1 Day change
-11.19%
52 Week Range
78.480
Analysis Updated At
2026/03/06
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CRISPR Therapeutics AG (CRSP) is not a strong buy for a beginner investor with a long-term strategy at this time. While the company has potential in its gene-editing pipeline and recent drug approval, the financial performance, negative revenue trends, and lack of significant trading signals suggest waiting for clearer signs of growth or stability before investing.

Technical Analysis

The MACD is positive but contracting, RSI is neutral at 49.845, and moving averages are converging, indicating no clear trend. The stock is trading near its pivot level of 57.175, with support at 53.454 and resistance at 60.896.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
13
Buy
5

Positive Catalysts

  • Approval of Casgevy, the first gene-editing drug for sickle cell disease and beta-thalassemia. Increased stake by Ark Innovation ETF, reflecting confidence in high-risk investments. Analysts maintain optimism about clinical updates and potential pipeline progress.

Neutral/Negative Catalysts

  • High treatment costs for Casgevy limit market revenue. Mixed analyst ratings and reduced price targets from some firms. No significant hedge fund or insider trading activity.

Financial Performance

In Q4 2025, revenue dropped by 97.58% YoY to $864,000. Net income improved but remained negative at -$130.6 million, with EPS at -1.37. Gross margin remained at 100%. The company has sufficient cash reserves but struggles with financial losses.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analyst ratings are mixed. Some firms, like Citi and Chardan, raised price targets and maintain Buy ratings, citing potential pipeline progress and Casgevy momentum. Others, like Morgan Stanley and JPMorgan, lowered price targets, citing limited revenue growth and financial challenges.

Wall Street analysts forecast CRSP stock price to rise
10 Analyst Rating
Wall Street analysts forecast CRSP stock price to rise
8 Buy
2 Hold
0 Sell
Strong Buy
Current: 58.780
sliders
Low
50
Averages
78.89
High
105
Current: 58.780
sliders
Low
50
Averages
78.89
High
105
Morgan Stanley
Morgan Stanley
Underweight
maintain
$32 -> $33
AI Analysis
2026-02-17
Reason
Morgan Stanley
Morgan Stanley
Price Target
$32 -> $33
AI Analysis
2026-02-17
maintain
Underweight
Reason
Morgan Stanley raised the firm's price target on Crispr Therapeutics (CRSP) to $33 from $32 and keeps an Underweight rating on the shares. The firm refreshed its Crispr estimates and reviewed incremental pipeline progress after partner Vertex Pharmaceuticals (VRTX) recently reported Q4 Casgevy sales.
Citi
Yigal Nochomovitz
Buy
maintain
$77 -> $80
2026-02-16
Reason
Citi
Yigal Nochomovitz
Price Target
$77 -> $80
2026-02-16
maintain
Buy
Reason
Citi analyst Yigal Nochomovitz raised the firm's price target on Crispr Therapeutics to $80 from $77 and keeps a Buy rating on the shares. The firm says the company's Casgevy revenue beat estimates in Q4. It sees Crisper's clinical and preclinical updates in 2026 driving potential upside in the shares.
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