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CRSP Should I Buy

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Intellectia

Should You Buy CRISPR Therapeutics AG (CRSP) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
54.830
1 Day change
4.60%
52 Week Range
78.480
Analysis Updated At
2026/05/08
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CRISPR Therapeutics is not a clear buy right now for a Beginner with a long-term horizon and $50,000-$100,000 to deploy. The stock has solid long-term potential and strong cash resources, but the current setup is mixed: the price trend is weak, the latest quarter missed EPS expectations, insider selling is rising, and there is no strong proprietary buy signal today. For an impatient investor who does not want to wait for a better entry, this is not the right moment to buy aggressively. The best direct call is hold.

Technical Analysis

CRSP is trading near 52.51, just above pivot support at 52.08 but still under near-term resistance at 54.64. The technical picture is bearish to neutral: MACD histogram is negative and expanding, RSI_6 is 47.2 showing no momentum edge, and moving averages are bearish with SMA_200 > SMA_20 > SMA_5. That means the stock is still in a weak trend, and the current rebound is not yet confirmed as a sustained uptrend. The short-term pattern data suggests possible upside over the next week, but the broader trend remains unfavorable for an immediate long-term entry.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Options sentiment is mildly bullish to neutral. A put-call ratio of 0.7 on both open interest and volume suggests more call interest than put interest, which is constructive. However, implied volatility is still elevated versus typical levels, and the stock does not have a strong options-driven breakout signal. Overall, options data supports moderate optimism, but not a decisive buy signal.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
1
Buy
13

Positive Catalysts

  • ["Citi raised its price target to $82 and kept a Buy rating on 2026-05-06.", "BofA kept a Buy rating and said Q1 updates were encouraging with few changes to the core thesis.", "Q1 revenue grew 68.55% year over year to $1.458 million.", "Cash and marketable securities were strong at $2.44 billion as of March 31, 2026.", "The company priced a $550 million convertible debt offering to support R&D and commercialization.", "Casgevy momentum and future pipeline updates remain key event-driven upside catalysts."]

Neutral/Negative Catalysts

  • ["The stock fell 4.83% during regular trading, showing weak immediate price action.", "Q1 GAAP EPS missed expectations at -$1.28.", "Net income remained deeply negative at -$122.9 million.", "Insiders have been selling, with selling up 476.16% over the last month.", "Technical trend is bearish with MACD negative and moving averages aligned unfavorably.", "Morgan Stanley still rates the stock Underweight, showing Wall Street remains divided.", "No AI Stock Picker or SwingMax signal is present today."]

Financial Performance

In Q1 2026, CRISPR Therapeutics posted revenue of $1.458 million, up 68.55% year over year, which is a strong top-line growth rate. However, profitability remains weak: net income was -$122.9 million and EPS was -$1.28, both worse than a year ago. Gross margin was 100%, but that is not enough to offset the lack of earnings power yet. The latest quarter was a growth improvement story, not a profits story.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analyst sentiment is mixed but leaning constructive. Recent target changes were mostly raised or maintained by bullish firms: Citi, BofA, Piper Sandler, Chardan, JPMorgan, and Needham all kept Buy/Overweight-type views with targets mostly in the $76-$110 range. The bearish side is still present, with Morgan Stanley maintaining Underweight and TD Cowen holding at Hold with a $45 target. Wall Street pros see upside from pipeline progress, cash strength, and Casgevy momentum, but cons remain the lack of profitability, dependence on pipeline execution, and valuation uncertainty.

Wall Street analysts forecast CRSP stock price to rise
10 Analyst Rating
Wall Street analysts forecast CRSP stock price to rise
8 Buy
2 Hold
0 Sell
Strong Buy
Current: 52.420
sliders
Low
50
Averages
78.89
High
105
Current: 52.420
sliders
Low
50
Averages
78.89
High
105
Citi
Buy
maintain
$80 -> $82
AI Analysis
2026-05-06
New
Reason
Citi
Price Target
$80 -> $82
AI Analysis
2026-05-06
New
maintain
Buy
Reason
Citi raised the firm's price target on Crispr Therapeutics to $82 from $80 and keeps a Buy rating on the shares.
BofA
Buy
maintain
$86 -> $83
2026-05-05
New
Reason
BofA
Price Target
$86 -> $83
2026-05-05
New
maintain
Buy
Reason
BofA lowered the firm's price target on Crispr Therapeutics to $83 from $86 and keeps a Buy rating on the shares. The firm comes away from the "encouraging" Q1 updates with "few changes to the core thesis," the analyst tells investors.
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