Xeris Biopharma (XERS) Shows Strong Momentum: Is It a Good Investment?
Momentum Investing Overview: Momentum investing involves buying stocks that are trending upwards, with the expectation of selling them at even higher prices. The Zacks Momentum Style Score helps identify stocks with strong momentum characteristics, such as price changes and earnings estimate revisions.
Xeris Biopharma Performance: Xeris Biopharma (XERS) has a Momentum Style Score of A and a Zacks Rank of #2 (Buy). The stock has shown significant price increases, with a 57.69% rise over the past quarter and 178.86% over the past year, outperforming the S&P 500.
Earnings Estimates and Trading Volume: Recent upward revisions in earnings estimates for XERS indicate positive momentum, with three estimates raised in the last two months. Additionally, the stock's average trading volume of 2,056,227 shares suggests bullish sentiment.
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Analyst Views on XERS
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Analyst Target Prices Indicate Potential for Pharmaceuticals ETF
- ETF Upside Potential: The iShares U.S. Pharmaceuticals ETF (IHE) has an implied analyst target price of $96.28 per unit, while trading at $86.15, indicating an 11.76% upside, reflecting market optimism about the ETF's future performance.
- MBX Stock Analysis: MBX BIOSCIENCES INC (MBX) trades at $35.83, with an analyst target price of $60.55, suggesting a potential upside of 69.01%, showcasing investor confidence in its future prospects.
- CRNX Stock Outlook: Crinetics Pharmaceuticals Inc (CRNX) has a current price of $51.32 and an analyst target of $83.46, indicating a 62.63% upside, reflecting positive market sentiment regarding its product and R&D advancements.
- XERS Investment Opportunity: Xeris Biopharma Holdings Inc (XERS) is priced at $7.14, with an analyst target of $11.14, showing a 56.05% upside, indicating analysts' optimism about its growth potential.
Xeris Anticipates 2025 Revenue of $292 Million, Exceeding Guidance
- Revenue Growth: Xeris anticipates total revenue of $292 million for 2025, exceeding the guidance range of $285-$290 million and reflecting a 44% increase from the previous year, indicating strong market demand and product performance.
- Product Performance: Recorlev® achieved net revenue of $45 million in Q4 2025 and $139 million for the full year, demonstrating increasing market acceptance in treating endogenous Cushing's syndrome.
- Patient Base Expansion: By the end of 2025, approximately 700 patients were on Recorlev® therapy, while Gvoke® saw revenue growth of over 13% year-over-year, showcasing the company's success in patient treatment and market penetration.
- Financial Stability: Xeris delivered positive adjusted EBITDA in every quarter, reinforcing the company's financial foundation and positioning it for sustained growth in the future.
Outlook Therapeutics Inc Faces 60.9% Drop After FDA Response on ONS-5010
- FDA Rejection: Outlook Therapeutics Inc's resubmission for the ONS-5010 biologics license application received a complete response letter from the FDA, indicating that the application cannot be approved in its current form, leading to a 60.9% drop in pre-market trading to $0.62, severely impacting investor confidence.
- Severe Market Reaction: The significant decline in Outlook Therapeutics' stock price reflects market concerns over its future product development prospects, which may hinder financing efforts and delay research progress.
- Other Stock Movements: In pre-market trading, Intelligent Bio Solutions Inc's stock fell 19.2% to $7.70 following the announcement of a $10 million private placement, indicating a decreased risk appetite among investors in the biotech sector.
- Overall Market Trend: While Nasdaq 100 futures rose about 1%, several stocks showed weakness in pre-market trading, suggesting that investor sentiment in the biotech sector is shaken, which could affect overall market mood.
Xeris Biopharma Shares Surge 7.59% as Competitor Corcept's FDA Approval Fails
- Stock Surge: Xeris Biopharma's shares rose 7.59% on Wednesday following the news that competitor Corcept Therapeutics' drug failed to gain FDA approval, reflecting investor confidence in Xeris's existing medication, Recorlev, which is expected to further solidify its market position.
- Market Potential: Analyst Glen Santangelo reiterated a buy rating on Xeris with a $10 price target, highlighting that the addressable market for Cushing's disease could grow from the current $1 billion to $3 billion by 2030, indicating significant growth potential for Xeris in this sector.
- FDA Decision Impact: Corcept's relacorilant was not approved by the FDA due to insufficient evidence of effectiveness, a decision that will reduce competition for Xeris's Recorlev, thereby enhancing its sales outlook.
- Clinical Trial Challenges: Although Corcept has vowed to continue pursuing approval, this will likely require additional clinical trials, potentially delaying its market entry and providing Xeris with more time and space to expand its market share.
Xeris Biopharma Gains 7% as Corcept's FDA Setback Boosts Investor Sentiment
- Stock Surge: Xeris Biopharma's stock rose over 7% on Wednesday as investors reacted positively to the news that competitor Corcept Therapeutics' drug was not approved by the FDA, reflecting optimism about Xeris's market prospects.
- Market Opportunity: Analyst Glen Santangelo reiterated a buy rating on Xeris with a $10 price target, forecasting that the addressable market for Cushing's disease could grow from $1 billion to $3 billion by 2030, positioning Xeris to benefit significantly.
- FDA Response: Corcept's complete response letter from the FDA cited a lack of additional evidence for the drug's effectiveness as the main reason for the rejection, allowing Xeris's Recorlev to maintain its market dominance.
- Clinical Trial Challenges: Although Corcept has vowed to continue seeking approval, this will likely require more clinical trials, which could diminish its competitive edge, further solidifying Xeris's position in the market.
Xeris Biopharma (XERS) Drops 9.3% Following XP-8121 Patent Milestone Announcement – Is the Bullish Outlook Still Valid?
Patent Milestone: Xeris Biopharma Holdings received a Notice of Allowance from the USPTO for its patent application on XP-8121, a once-weekly, subcutaneous levothyroxine formulation, enhancing its intellectual property protection in the levothyroxine market.
Investment Outlook: The patent approval is seen as a positive long-term catalyst for Xeris, potentially reducing reliance on existing products, but investors should remain cautious about the company's current dependence on its commercial drugs and the risks associated with rising R&D and SG&A costs.
Revenue Projections: Xeris is projected to achieve $440.9 million in revenue and $84.8 million in earnings by 2028, necessitating significant annual growth, while current valuations among analysts vary widely, indicating differing expectations for the company's future performance.
Research and Analysis: Simply Wall St offers a comprehensive analysis of Xeris Biopharma, highlighting key rewards and risks, and emphasizes the importance of evaluating the company's financial health and market position before making investment decisions.
Analyst Target Prices Indicate Potential for Pharmaceuticals ETF
- ETF Upside Potential: The iShares U.S. Pharmaceuticals ETF (IHE) has an implied analyst target price of $96.28 per unit, while trading at $86.15, indicating an 11.76% upside, reflecting market optimism about the ETF's future performance.
- MBX Stock Analysis: MBX BIOSCIENCES INC (MBX) trades at $35.83, with an analyst target price of $60.55, suggesting a potential upside of 69.01%, showcasing investor confidence in its future prospects.
- CRNX Stock Outlook: Crinetics Pharmaceuticals Inc (CRNX) has a current price of $51.32 and an analyst target of $83.46, indicating a 62.63% upside, reflecting positive market sentiment regarding its product and R&D advancements.
- XERS Investment Opportunity: Xeris Biopharma Holdings Inc (XERS) is priced at $7.14, with an analyst target of $11.14, showing a 56.05% upside, indicating analysts' optimism about its growth potential.
Xeris Anticipates 2025 Revenue of $292 Million, Exceeding Guidance
- Revenue Growth: Xeris anticipates total revenue of $292 million for 2025, exceeding the guidance range of $285-$290 million and reflecting a 44% increase from the previous year, indicating strong market demand and product performance.
- Product Performance: Recorlev® achieved net revenue of $45 million in Q4 2025 and $139 million for the full year, demonstrating increasing market acceptance in treating endogenous Cushing's syndrome.
- Patient Base Expansion: By the end of 2025, approximately 700 patients were on Recorlev® therapy, while Gvoke® saw revenue growth of over 13% year-over-year, showcasing the company's success in patient treatment and market penetration.
- Financial Stability: Xeris delivered positive adjusted EBITDA in every quarter, reinforcing the company's financial foundation and positioning it for sustained growth in the future.
Outlook Therapeutics Inc Faces 60.9% Drop After FDA Response on ONS-5010
- FDA Rejection: Outlook Therapeutics Inc's resubmission for the ONS-5010 biologics license application received a complete response letter from the FDA, indicating that the application cannot be approved in its current form, leading to a 60.9% drop in pre-market trading to $0.62, severely impacting investor confidence.
- Severe Market Reaction: The significant decline in Outlook Therapeutics' stock price reflects market concerns over its future product development prospects, which may hinder financing efforts and delay research progress.
- Other Stock Movements: In pre-market trading, Intelligent Bio Solutions Inc's stock fell 19.2% to $7.70 following the announcement of a $10 million private placement, indicating a decreased risk appetite among investors in the biotech sector.
- Overall Market Trend: While Nasdaq 100 futures rose about 1%, several stocks showed weakness in pre-market trading, suggesting that investor sentiment in the biotech sector is shaken, which could affect overall market mood.
Xeris Biopharma Shares Surge 7.59% as Competitor Corcept's FDA Approval Fails
- Stock Surge: Xeris Biopharma's shares rose 7.59% on Wednesday following the news that competitor Corcept Therapeutics' drug failed to gain FDA approval, reflecting investor confidence in Xeris's existing medication, Recorlev, which is expected to further solidify its market position.
- Market Potential: Analyst Glen Santangelo reiterated a buy rating on Xeris with a $10 price target, highlighting that the addressable market for Cushing's disease could grow from the current $1 billion to $3 billion by 2030, indicating significant growth potential for Xeris in this sector.
- FDA Decision Impact: Corcept's relacorilant was not approved by the FDA due to insufficient evidence of effectiveness, a decision that will reduce competition for Xeris's Recorlev, thereby enhancing its sales outlook.
- Clinical Trial Challenges: Although Corcept has vowed to continue pursuing approval, this will likely require additional clinical trials, potentially delaying its market entry and providing Xeris with more time and space to expand its market share.
Xeris Biopharma Gains 7% as Corcept's FDA Setback Boosts Investor Sentiment
- Stock Surge: Xeris Biopharma's stock rose over 7% on Wednesday as investors reacted positively to the news that competitor Corcept Therapeutics' drug was not approved by the FDA, reflecting optimism about Xeris's market prospects.
- Market Opportunity: Analyst Glen Santangelo reiterated a buy rating on Xeris with a $10 price target, forecasting that the addressable market for Cushing's disease could grow from $1 billion to $3 billion by 2030, positioning Xeris to benefit significantly.
- FDA Response: Corcept's complete response letter from the FDA cited a lack of additional evidence for the drug's effectiveness as the main reason for the rejection, allowing Xeris's Recorlev to maintain its market dominance.
- Clinical Trial Challenges: Although Corcept has vowed to continue seeking approval, this will likely require more clinical trials, which could diminish its competitive edge, further solidifying Xeris's position in the market.
Xeris Biopharma (XERS) Drops 9.3% Following XP-8121 Patent Milestone Announcement – Is the Bullish Outlook Still Valid?
Patent Milestone: Xeris Biopharma Holdings received a Notice of Allowance from the USPTO for its patent application on XP-8121, a once-weekly, subcutaneous levothyroxine formulation, enhancing its intellectual property protection in the levothyroxine market.
Investment Outlook: The patent approval is seen as a positive long-term catalyst for Xeris, potentially reducing reliance on existing products, but investors should remain cautious about the company's current dependence on its commercial drugs and the risks associated with rising R&D and SG&A costs.
Revenue Projections: Xeris is projected to achieve $440.9 million in revenue and $84.8 million in earnings by 2028, necessitating significant annual growth, while current valuations among analysts vary widely, indicating differing expectations for the company's future performance.
Research and Analysis: Simply Wall St offers a comprehensive analysis of Xeris Biopharma, highlighting key rewards and risks, and emphasizes the importance of evaluating the company's financial health and market position before making investment decisions.
