Xenetic Biosciences Reports Q1 Loss, Misses Revenue Estimates
Xenetic Biosciences Quarterly Performance:
- Reported a quarterly loss of $0.78 per share, slightly better than expected.
- Earnings surprise of 1.27%, beating estimates for the fourth consecutive quarter.
- Revenues of $0.51 million missed estimates by 21.39%.
- Stock price increased by 13.8% this year compared to S&P 500's gain of 8.8%.
Future Outlook for Xenetic Biosciences:
- Uncertainty about future stock performance.
- Earnings outlook and estimate revisions are crucial indicators.
- Current Zacks Rank #3 (Hold) suggests market performance in the near future.
Affimed N.V. Expectations:
- Expected quarterly loss of $1.86 per share, with a 19.1% increase from the previous year.
- Anticipated revenues of $1.76 million, down 63.7% from the same period last year.
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- Successful Clinical Trial: Upstream Bio's Phase 2 VALIANT trial results for Verekitug demonstrated significant efficacy, with a 56% reduction in annual asthma attacks at 100 mg and a 39% reduction at 400 mg, laying a solid foundation for the company's future market prospects.
- Positive Patient Response: The study involving 478 participants supported Verekitug's safety profile, with most patients showing improved lung function, indicating the drug's strong potential in treating severe asthma.
- Long-Term Study Expansion: More than 90% of eligible participants have enrolled in the VALOUR long-term extension trial to further assess the treatment's durability, providing additional data support for the drug's market launch.
- Positive Market Reaction: Following the encouraging trial results, Upstream Bio's shares surged nearly 20% in pre-market trading, reflecting investor confidence and expectations for the company's future growth.

Pharmaceutical Stock Movements: Several pharmaceutical stocks, including Xenetic Biosciences, Universe Pharmaceuticals, XTL Biopharmaceuticals, and Acurx Pharmaceuticals, saw significant pre-market gains despite no clear news or announcements explaining the rise.
Speculative Trading Influence: The surge in these stocks may be linked to speculative trading following a massive rally in Galecto shares, which spiked without news and then fell, indicating that retail traders are shifting their focus to other stocks for potential gains.
Earnings Performance: Xenetic Biosciences reported a quarterly loss of $0.45 per share, better than the expected loss of $0.64, marking a 29.69% earnings surprise; however, revenues of $0.59 million fell short of estimates by 7.81%.
Market Outlook: The company's stock has underperformed with a 30.8% decline this year, and its future performance will depend on management's commentary and revisions to earnings estimates, currently rated as Zacks Rank #3 (Hold).

Research Findings: Xenetic Biosciences presented preclinical data showing that co-administration of deoxyribonuclease I (DNase I) with CAR T cells significantly suppressed lung metastasis in a murine melanoma model, enhancing tumor control and survival compared to CAR T cell therapy alone.
Immune Response Improvement: The combination treatment led to increased infiltration of T and CAR T cells in tumors and reduced markers of T cell exhaustion, indicating that DNase I helps counteract the immunosuppressive environment of tumors.
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Earnings Performance: Progyny (PGNY) reported quarterly earnings of $0.40 per share, exceeding estimates and showing significant growth from $0.16 a year ago, but its revenues of $286.63 million fell short of expectations.
Stock Outlook: Despite the positive earnings surprise, Progyny's stock has underperformed this year, with a Zacks Rank #4 (Sell) indicating expected further underperformance, influenced by unfavorable estimate revisions and the overall industry ranking.







