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ACXP Overview

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ET
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Intellectia

Loading chart...

High
4.439
Open
3.820
VWAP
3.76
Vol
378.56K
Mkt Cap
9.99M
Low
3.350
Amount
1.43M
EV/EBITDA(TTM)
--
Total Shares
2.86M
EV
3.18M
EV/OCF(TTM)
--
P/S(TTM)
--
Acurx Pharmaceuticals, Inc. is a late-stage biopharmaceutical company focused on developing a new class of small molecule antibiotics for difficult-to-treat bacterial infections. It develops antibiotic candidates with a Gram-positive selective spectrum (GPSS) that block the active site of the Gram positive specific bacterial enzyme deoxyribonucleic acid (DNA) polymerase IIIC (pol IIIC), inhibiting DNA replication and leading to Gram-positive bacterial cell death. Its research and development (R&D) pipeline include antibiotic product candidates that target Gram-positive bacteria, including Clostridioides difficile (C. difficile), methicillin-resistant Staphylococcus aureus (MRSA), vancomycin resistant Enterococcus (VRE), drug-resistant Streptococcus pneumoniae (DRSP) and B. anthracis (anthrax; a Bioterrorism Category A Threat-Level pathogen). Its lead antibiotic candidate, ibezapolstat targets the pol IIIC enzyme.
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Events Timeline

(ET)
2026-03-13
07:10:00
Company Ends Quarter with Cash of $7.6M
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2026-03-09 (ET)
2026-03-09
08:10:00
Acurx Pharmaceuticals Initiates Clinical Trial for Recurrent C. difficile Infection
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2026-02-02 (ET)
2026-02-02
17:00:00
Acurx Files to Sell 750,000 Shares of Common Stock
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2025-11-12 (ET)
2025-11-12
07:06:11
Acurx announces Q3 earnings per share of $1.23, compared to a loss of $3.45 in the same period last year.
select
2025-11-10 (ET)
2025-11-10
08:08:39
Acurx reveals findings from ibezapolstat research study
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2025-10-09 (ET)
2025-10-09
07:32:01
Acurx Receives New Patent for Inhibitors of DNA Polymerase IIIC
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News

Newsfilter
8.5
03-30Newsfilter
PinnedAcurx Secures New Patent to Strengthen IP Portfolio
  • Patent Protection Expansion: Acurx Pharmaceuticals has secured a new patent from the Korean Intellectual Property Office covering DNA Polymerase IIIC inhibitors, further strengthening its intellectual property portfolio, having already obtained four U.S. patents and patents in Israel, Japan, India, Australia, and Korea, indicating a robust global IP strategy.
  • Clinical Trial Readiness: Acurx's lead product candidate, ibezapolstat, is ready to advance to international Phase 3 pivotal registration trials for oral treatment of acute Clostridioides difficile infection, marking a significant milestone in antibiotic development that could transform treatment paradigms.
  • Innovative Drug Development: The company is initiating a groundbreaking clinical trial for multiply-recurrent CDI, which has the potential to shift treatment from two agents to one, showcasing the innovative potential and competitive edge of its research pipeline.
  • Broad Market Prospects: Acurx's R&D pipeline focuses on developing new classes of small molecule antibiotics for difficult-to-treat bacterial infections, particularly targeting drug-resistant bacteria, which is expected to create significant market opportunities amid increasing antibiotic demand.
PRnewswire
8.5
03-30PRnewswire
Acurx Secures New Patent to Strengthen IP Portfolio
  • Patent Protection Expansion: Acurx has secured a new patent from the Korean Intellectual Property Office covering DNA Polymerase IIIC inhibitors, further strengthening its intellectual property portfolio, having already obtained four U.S. patents and patents in Israel, Japan, India, Australia, and Korea, indicating a robust global IP strategy.
  • Clinical Trial Readiness: Acurx's lead product candidate, ibezapolstat, is ready to advance to international Phase 3 pivotal registration trials for oral treatment of acute C. difficile infection, marking a significant milestone in antibiotic development that could transform treatment paradigms.
  • Innovative R&D Platform: The company is developing a new class of small molecule antibiotics for difficult-to-treat bacterial infections, leveraging an AI-supported drug discovery platform, which is expected to create a transformational shift in the treatment of serious infections, particularly against MRSA and other resistant strains.
  • Significant Market Potential: Acurx's R&D pipeline includes antibiotic candidates targeting various life-threatening bacteria, especially Bacillus anthracis, a Category A bioterrorism threat, highlighting its strategic importance in public health and potential for future market recognition.
seekingalpha
9.5
03-13seekingalpha
Acurx Pharmaceuticals Q4 2025 Earnings Call Highlights
  • Funding Progress: Acurx Pharmaceuticals secured $1.4 million in gross proceeds from the execution of Series F Warrants in October 2025, enhancing liquidity to support upcoming clinical trials and operational needs.
  • Clinical Trial Launch: The company plans to initiate a new open-label pilot trial for recurrent CDI in the second half of 2026, with full enrollment expected within 12 to 15 months and projected costs between $4 million to $5 million, indicating a proactive approach in clinical development.
  • R&D Expense Reduction: Research and development expenses for Q4 2025 were reported at $0.3 million, down 62.5% from $0.8 million in Q4 2024, reflecting effective cost control measures, while total annual R&D expenses decreased from $5.4 million to $1.8 million, showcasing improved financial health.
  • FDA Regulatory Dynamics: Management highlighted the FDA's potential shift to a one-trial registration requirement, which, if formalized, could accelerate the approval timeline for ibezapolstat, enhancing the company's competitive position and market entry speed.
Benzinga
9.5
03-13Benzinga
Acurx Pharmaceuticals Reports Q4 Loss, Shares Drop
  • Financial Loss: Acurx Pharmaceuticals reported a net loss of $0.73 per diluted share for Q4 2025, which, while better than the expected $1.65 loss, indicates ongoing financial challenges that may affect investor confidence.
  • Cash Position: The company ended the quarter with $7.6 million in cash, up from $3.7 million a year earlier, suggesting improved financing efforts, yet ongoing operational losses remain a concern.
  • Clinical Trial Progress: Acurx is preparing for international Phase 3 clinical trials for its lead antibiotic candidate, Ibezapolstat, aimed at treating C. difficile infections, which is crucial in addressing the rising global antibiotic resistance issue.
  • Future Outlook: Acurx is set to provide its next financial update on May 12, 2026, with analysts estimating an improved EPS loss of $1.24, reflecting cautious optimism about the company's future developments.
PRnewswire
9.5
03-13PRnewswire
Acurx Pharmaceuticals Reports 2025 Financial Highlights
  • Improved Cash Position: As of December 31, 2025, Acurx's cash balance reached $7.6 million, a significant increase from $3.7 million in 2024, indicating progress in financing that supports ongoing R&D activities.
  • Significant Reduction in R&D Expenses: R&D expenses for Q4 2025 were $0.3 million, down from $0.8 million in Q4 2024, primarily due to lower manufacturing and consulting costs, reflecting effective cost control measures by the company.
  • Decreased Net Loss: The net loss for Q4 2025 was $1.6 million, or $0.73 per share, an improvement from a $2.8 million loss and $3.29 per share in Q4 2024, indicating positive changes in the company's financial health.
  • Clinical Trial Readiness: Acurx's lead antibiotic candidate, Ibezapolstat, is set to enter international Phase 3 clinical trials, having received positive regulatory guidance from the EMA, which, if successful, will facilitate its marketing authorization application in Europe, highlighting its strategic importance.
Newsfilter
9.5
03-13Newsfilter
Acurx Pharmaceuticals Reports 2025 Financial Results and Clinical Advances
  • Funding Progress: In October 2025, Acurx raised approximately $1.4 million through the exercise of 170,068 Series F Warrants, enhancing cash flow to support ongoing R&D projects and operational stability.
  • Research Collaboration Outcomes: In November 2025, results from Acurx's collaboration with Leiden University Medical Center were published in Nature Communications, revealing the target structure of the DNA polymerase IIIC inhibitor ibezapolstat for the first time, establishing a strong foundation for the development of new antibiotics and showcasing the company's research capabilities.
  • Clinical Trial Launch: On March 9, 2026, Acurx announced the initiation of a groundbreaking clinical trial for ibezapolstat in patients with recurrent CDI, aiming to shift treatment paradigms from two agents to one, which could position the company as a leader in this therapeutic area if successful.
  • Improved Financial Position: As of December 31, 2025, Acurx reported a cash balance of $7.6 million, a significant increase from $3.7 million in 2024, with reductions in R&D and administrative expenses indicating effective cost management and financial health.
Wall Street analysts forecast ACXP stock price to rise
2 Analyst Rating
Wall Street analysts forecast ACXP stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
30.00
Averages
30.50
High
31.00
Current: 0.000
sliders
Low
30.00
Averages
30.50
High
31.00
Alliance Global
Buy
maintain
$20 -> $10
AI Analysis
2026-03-13
Reason
Alliance Global
Price Target
$20 -> $10
AI Analysis
2026-03-13
maintain
Buy
Reason
Alliance Global lowered the firm's price target on Acurx to $10 from $20 and keeps a Buy rating on the shares following the Q4 report. The firm pushed back its expected FDA approval of ibezapolstat for C. difficile infection to 2031 from 2028, but says the new open label Phase 2 "will afford the opportunity for additional data quicker and cheaper."
H.C. Wainwright
H.C. Wainwright
NULL -> Buy
upgrade
$8 -> $31
2025-08-12
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$8 -> $31
2025-08-12
upgrade
NULL -> Buy
Reason
H.C. Wainwright adjusted the firm's price target on Acurx to $31 from $8 and keeps a Buy rating on the shares following the recent 1-for-20 reverse stock split. The firm believes the company's lead asset ibezapolstat is making steady progress as it prepares to enter Phase 3 evaluation.
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Valuation Metrics

The current forward P/E ratio for Acurx Pharmaceuticals Inc (ACXP.O) is -0.58, compared to its 5-year average forward P/E of -2.35. For a more detailed relative valuation and DCF analysis to assess Acurx Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.35
Current PE
-0.58
Overvalued PE
-1.12
Undervalued PE
-3.58

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.05
Current EV/EBITDA
0.02
Overvalued EV/EBITDA
0.10
Undervalued EV/EBITDA
-0.20

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.03
Current PS
0.00
Overvalued PS
0.27
Undervalued PS
-0.21

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Frequently Asked Questions

What is Acurx Pharmaceuticals Inc (ACXP) stock price today?

The current price of ACXP is 3.5 USD — it has decreased -6.91

What is Acurx Pharmaceuticals Inc (ACXP)'s business?

Acurx Pharmaceuticals, Inc. is a late-stage biopharmaceutical company focused on developing a new class of small molecule antibiotics for difficult-to-treat bacterial infections. It develops antibiotic candidates with a Gram-positive selective spectrum (GPSS) that block the active site of the Gram positive specific bacterial enzyme deoxyribonucleic acid (DNA) polymerase IIIC (pol IIIC), inhibiting DNA replication and leading to Gram-positive bacterial cell death. Its research and development (R&D) pipeline include antibiotic product candidates that target Gram-positive bacteria, including Clostridioides difficile (C. difficile), methicillin-resistant Staphylococcus aureus (MRSA), vancomycin resistant Enterococcus (VRE), drug-resistant Streptococcus pneumoniae (DRSP) and B. anthracis (anthrax; a Bioterrorism Category A Threat-Level pathogen). Its lead antibiotic candidate, ibezapolstat targets the pol IIIC enzyme.

What is the price predicton of ACXP Stock?

Wall Street analysts forecast ACXP stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ACXP is30.50 USD with a low forecast of 30.00 USD and a high forecast of 31.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Acurx Pharmaceuticals Inc (ACXP)'s revenue for the last quarter?

Acurx Pharmaceuticals Inc revenue for the last quarter amounts to -1.62M USD, decreased -41.87

What is Acurx Pharmaceuticals Inc (ACXP)'s earnings per share (EPS) for the last quarter?

Acurx Pharmaceuticals Inc. EPS for the last quarter amounts to USD, decreased

How many employees does Acurx Pharmaceuticals Inc (ACXP). have?

Acurx Pharmaceuticals Inc (ACXP) has 4 emplpoyees as of March 31 2026.

What is Acurx Pharmaceuticals Inc (ACXP) market cap?

Today ACXP has the market capitalization of 9.99M USD.