Theravance Biopharma to Host Virtual KOL Investor Event to Review Ampreloxetine Phase 3 Clinical Development Program, Ahead of Topline Data in Q1 2026, on December 8, 2025
Event Announcement: Theravance Biopharma will host a virtual investor event on December 8, 2025, featuring Dr. Horacio Kaufmann discussing the unmet medical need for neurogenic orthostatic hypotension (nOH) in multiple system atrophy (MSA) patients and the potential of ampreloxetine as a treatment.
CYPRESS Study Overview: The event will provide insights into the ongoing Phase 3 CYPRESS study of ampreloxetine, including its design and the anticipated topline results expected in early 2026, as well as the commercial strategy for the drug.
About Ampreloxetine: Ampreloxetine is an investigational norepinephrine reuptake inhibitor aimed at treating symptomatic nOH in MSA patients, showing promising results in previous studies, including increased norepinephrine levels and symptom improvement.
Multiple System Atrophy (MSA) Context: MSA is a progressive disorder affecting movement and autonomic functions, with a significant percentage of patients experiencing nOH symptoms, highlighting the need for effective treatments like ampreloxetine.
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