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TBPH Should I Buy

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Intellectia

Should You Buy Theravance Biopharma Inc (TBPH) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
16.790
1 Day change
0.30%
52 Week Range
21.030
Analysis Updated At
2026/04/24
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Theravance Biopharma Inc (TBPH) is not a strong buy at the moment for a beginner investor with a long-term horizon. While the company has shown some positive revenue growth, the recent failure of its Phase 3 CYPRESS study, ongoing legal investigations, and significant financial losses make it a risky investment. Additionally, there are no strong trading signals or positive catalysts to justify immediate action.

Technical Analysis

The technical indicators are mixed. The MACD is slightly positive, and moving averages are bullish (SMA_5 > SMA_20 > SMA_200). However, the RSI is neutral at 40.747, and the stock is trading near its support level of 16.301, suggesting limited upside potential in the short term.

Options Data

Bearish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
1
Buy
10

Positive Catalysts

  • The company has locked exclusivity through April 2039 for its single-asset story, which removes some uncertainty. Additionally, Yupelri continues to grow and generate milestones, and Trelegy payments remain significant.

Neutral/Negative Catalysts

  • The failure of the Phase 3 CYPRESS study and the discontinuation of the ampreloxetine program have significantly impacted the company's prospects. The ongoing investigation for potential securities fraud and unlawful business practices adds further risk. Additionally, the company has experienced a sharp decline in net income and EPS.

Financial Performance

In Q4 2025, revenue increased by 144.70% YoY to $45.89M, but net income dropped by -493.02% YoY to -$61.02M. EPS also fell by -470.97% YoY to 1.15. Despite a 100% gross margin, the financial performance indicates significant challenges.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analyst sentiment is mixed to negative. Recent upgrades raised price targets slightly (e.g., B. Riley to $17 from $14), but the stock has seen multiple downgrades following the CYPRESS study failure. Analysts highlight limited visibility into upside drivers and significant cost-cutting measures.

Wall Street analysts forecast TBPH stock price to rise
5 Analyst Rating
Wall Street analysts forecast TBPH stock price to rise
4 Buy
1 Hold
0 Sell
Strong Buy
Current: 16.740
sliders
Low
13
Averages
28.4
High
42
Current: 16.740
sliders
Low
13
Averages
28.4
High
42
B. Riley
Neutral
maintain
$14 -> $17
AI Analysis
2026-04-07
Reason
B. Riley
Price Target
$14 -> $17
AI Analysis
2026-04-07
maintain
Neutral
Reason
B. Riley raised the firm's price target on Theravance Biopharma (TBPH) to $17 from $14 and keeps a Neutral rating on the shares. The final generic settlement with Mankind (MNKD) locks exclusivity through April 2039, "removing the last overhang on a clean single-asset story," the analyst tells investors.
TD Cowen
Hold
maintain
$13 -> $15
2026-03-23
Reason
TD Cowen
Price Target
$13 -> $15
2026-03-23
maintain
Hold
Reason
TD Cowen raised the firm's price target on Theravance Biopharma to $15 from $13 and keeps a Hold rating on the shares. The firm said they reported Q4 results including non-GAAP net income of $3.1MM and year end cash of $326MM. Following CYPRESS's failure, significant cost cuts are underway and expected to complete by early Q3, leaving the company with $60-70MM in annualized cash flow.
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