Significant ETF Withdrawals: ITOT, TSLA, PLTR, TMO
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 11 2025
0mins
Should l Buy TMO?
Source: NASDAQ.COM
52-Week Range of ITOT: ITOT's share price has a 52-week low of $105 and a high of $150.70, with the last trade recorded at $150.23.
Understanding ETFs: Exchange traded funds (ETFs) function like stocks, where investors buy and sell "units" that can be created or destroyed based on demand.
Monitoring ETF Flows: Weekly monitoring of shares outstanding helps identify ETFs with significant inflows (new units created) or outflows (units destroyed), impacting the underlying holdings.
Author's Views: The opinions expressed in the article are those of the author and do not necessarily represent Nasdaq, Inc.
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Analyst Views on TMO
Wall Street analysts forecast TMO stock price to rise
19 Analyst Rating
18 Buy
1 Hold
0 Sell
Strong Buy
Current: 478.120
Low
580.00
Averages
658.89
High
750.00
Current: 478.120
Low
580.00
Averages
658.89
High
750.00
About TMO
Thermo Fisher Scientific Inc. is engaged in accelerating life sciences research, solving complex analytical challenges, increasing laboratory productivity, and improving patient health through diagnostics and the development and manufacture of life-changing therapies. Through its Life Sciences Solutions segment, it provides a portfolio of reagents, instruments and consumables used in biological and medical research, the discovery and production of new drugs and vaccines as well as diagnosis of infection and disease. Through its Analytical Instruments segment, it provides instruments and the supporting consumables, software and services that are used for a range of applications. Its Specialty Diagnostics segment offers a range of diagnostic test kits, reagents, culture media, instruments and associated products. Its Laboratory Products and Biopharma Services segment offers virtually everything needed for the laboratory. It also provides purification and filtration technologies.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
THERMO FISHER SCIENTIFIC FINALIZES PURCHASE OF CLARIO HOLDINGS, INC.
Acquisition Announcement: The Thermo Fisher Scientific has completed the acquisition of Clario Holdings, Inc.
Strategic Importance: This acquisition is expected to enhance Thermo Fisher's capabilities in the life sciences sector.
See More
High Options Volume for New York Times and Thermo Fisher Scientific
- New York Times Options: New York Times (NYT) options volume reached 22,095 contracts today, representing approximately 2.2 million shares, which constitutes 98.3% of its average daily trading volume over the past month, indicating strong market interest in its future performance.
- High Volume Put Options: Within NYT, the $80 strike put option saw 10,001 contracts traded today, representing about 1.0 million shares, reflecting investor expectations of potential price declines, which could impact stock volatility.
- Thermo Fisher Options: Thermo Fisher Scientific Inc (TMO) options volume reached 19,487 contracts today, equating to approximately 1.9 million shares, accounting for 94% of its average daily trading volume over the past month, showcasing active market interest in its stock.
- Put Option Concerns: For TMO, the $570 strike put option traded 2,100 contracts today, representing around 210,000 shares, indicating investor concerns about potential future declines, which may affect its market performance.
See More
HSBC Downgrades Eli Lilly, Signals Cooling Obesity Drug Market
- Rating Downgrade: HSBC analysts downgraded Eli Lilly from Hold to Reduce, slashing the target price from $1,070 to $850, citing that the stock is currently 'priced to perfection' and faces significant competitive headwinds.
- Market Expectation Correction: Analysts argue that the total addressable market (TAM) for obesity drugs is overestimated, likely to be between $80 billion and $120 billion by 2032, rather than the consensus expectation of $150 billion, indicating that market demand may not be as robust as anticipated.
- Intensifying Competition: While Lilly's stock has risen 20% over the past year, significantly outperforming Novo Nordisk's 55% decline, analysts warn that as competitors like Novo push back in pricing, the battle for market share will intensify.
- Healthcare Sector Outlook: Despite caution on Lilly and the obesity drug market, HSBC remains bullish on the broader healthcare sector, viewing it as a safer investment amid AI disruption and geopolitical instability, and recommends focusing on AstraZeneca, AbbVie, and Johnson & Johnson for better risk-reward profiles.
See More
Analysis of XLV ETF's 52-Week Price Fluctuations
- Price Range Analysis: The XLV ETF has a 52-week low of $127.35 and a high of $160.59, with the last trade at $153.55, indicating stability and potential investment appeal in the current market.
- Technical Analysis Tool: Comparing the current share price to the 200-day moving average provides investors with valuable insights for technical analysis, aiding in market trend assessment and timing of investments.
- ETF Trading Mechanism: ETFs trade like stocks, where investors buy and sell 'units' that can be created or destroyed based on demand, impacting liquidity and market performance.
- Inflows and Outflows Monitoring: Weekly monitoring of changes in shares outstanding helps identify ETFs experiencing significant inflows or outflows, allowing investors to capitalize on market dynamics and opportunities.
See More
Baron Health Care Fund Reports Strong Q4 2025 Performance
- Quarterly Growth: For the quarter ending December 31, 2025, the Baron Health Care Fund increased by 13.10%, significantly outperforming the Russell 3000 Health Care Index's 11.92% and the Russell 3000 Index's 2.40%, indicating strong performance in the healthcare sector.
- Key Contributors: Companies such as Eli Lilly, Cidara Therapeutics, and Argenx SE were major contributors this quarter, reflecting ongoing momentum in GLP-1 therapies and innovation in biotechnology, which drove the fund's gains.
- Portfolio Adjustments: The fund added seven new positions and exited ten during the quarter, bringing the total number of positions to 43, demonstrating its agile investment strategy in response to market changes.
- Risk Management Actions: The fund reduced its positions in Stryker and Boston Scientific due to valuation concerns while also decreasing its stake in Arcellx to manage risks associated with increasing competition and regulatory challenges, showcasing its responsiveness to market dynamics.
See More
Thermo Fisher CEO Sells 10,000 Shares
- Executive Sell-off: Marc N Casper, Chairman and CEO of Thermo Fisher, sold 10,000 shares on March 3, 2026, which may raise market concerns about the company's future performance, as executive sell-offs are often viewed as negative signals regarding company outlook.
- Market Reaction: Such sell-off actions could lead to a decline in investor confidence in Thermo Fisher, potentially impacting its stock performance, especially in the current market environment where investors are particularly sensitive to executive signals.
- Shareholding Structure Change: This transaction may alter Casper's ownership percentage, further influencing market perceptions of management stability, particularly as the company faces increasing competition.
- Strategic Implications: While the sell-off may be interpreted as a negative signal, it could also be part of the executive's personal financial planning, prompting investors to focus on the company's future performance and strategic direction to assess its long-term investment value.
See More
THERMO FISHER SCIENTIFIC FINALIZES PURCHASE OF CLARIO HOLDINGS, INC.
Acquisition Announcement: The Thermo Fisher Scientific has completed the acquisition of Clario Holdings, Inc.
Strategic Importance: This acquisition is expected to enhance Thermo Fisher's capabilities in the life sciences sector.
See More
High Options Volume for New York Times and Thermo Fisher Scientific
- New York Times Options: New York Times (NYT) options volume reached 22,095 contracts today, representing approximately 2.2 million shares, which constitutes 98.3% of its average daily trading volume over the past month, indicating strong market interest in its future performance.
- High Volume Put Options: Within NYT, the $80 strike put option saw 10,001 contracts traded today, representing about 1.0 million shares, reflecting investor expectations of potential price declines, which could impact stock volatility.
- Thermo Fisher Options: Thermo Fisher Scientific Inc (TMO) options volume reached 19,487 contracts today, equating to approximately 1.9 million shares, accounting for 94% of its average daily trading volume over the past month, showcasing active market interest in its stock.
- Put Option Concerns: For TMO, the $570 strike put option traded 2,100 contracts today, representing around 210,000 shares, indicating investor concerns about potential future declines, which may affect its market performance.
See More
HSBC Downgrades Eli Lilly, Signals Cooling Obesity Drug Market
- Rating Downgrade: HSBC analysts downgraded Eli Lilly from Hold to Reduce, slashing the target price from $1,070 to $850, citing that the stock is currently 'priced to perfection' and faces significant competitive headwinds.
- Market Expectation Correction: Analysts argue that the total addressable market (TAM) for obesity drugs is overestimated, likely to be between $80 billion and $120 billion by 2032, rather than the consensus expectation of $150 billion, indicating that market demand may not be as robust as anticipated.
- Intensifying Competition: While Lilly's stock has risen 20% over the past year, significantly outperforming Novo Nordisk's 55% decline, analysts warn that as competitors like Novo push back in pricing, the battle for market share will intensify.
- Healthcare Sector Outlook: Despite caution on Lilly and the obesity drug market, HSBC remains bullish on the broader healthcare sector, viewing it as a safer investment amid AI disruption and geopolitical instability, and recommends focusing on AstraZeneca, AbbVie, and Johnson & Johnson for better risk-reward profiles.
See More
Analysis of XLV ETF's 52-Week Price Fluctuations
- Price Range Analysis: The XLV ETF has a 52-week low of $127.35 and a high of $160.59, with the last trade at $153.55, indicating stability and potential investment appeal in the current market.
- Technical Analysis Tool: Comparing the current share price to the 200-day moving average provides investors with valuable insights for technical analysis, aiding in market trend assessment and timing of investments.
- ETF Trading Mechanism: ETFs trade like stocks, where investors buy and sell 'units' that can be created or destroyed based on demand, impacting liquidity and market performance.
- Inflows and Outflows Monitoring: Weekly monitoring of changes in shares outstanding helps identify ETFs experiencing significant inflows or outflows, allowing investors to capitalize on market dynamics and opportunities.
See More
Baron Health Care Fund Reports Strong Q4 2025 Performance
- Quarterly Growth: For the quarter ending December 31, 2025, the Baron Health Care Fund increased by 13.10%, significantly outperforming the Russell 3000 Health Care Index's 11.92% and the Russell 3000 Index's 2.40%, indicating strong performance in the healthcare sector.
- Key Contributors: Companies such as Eli Lilly, Cidara Therapeutics, and Argenx SE were major contributors this quarter, reflecting ongoing momentum in GLP-1 therapies and innovation in biotechnology, which drove the fund's gains.
- Portfolio Adjustments: The fund added seven new positions and exited ten during the quarter, bringing the total number of positions to 43, demonstrating its agile investment strategy in response to market changes.
- Risk Management Actions: The fund reduced its positions in Stryker and Boston Scientific due to valuation concerns while also decreasing its stake in Arcellx to manage risks associated with increasing competition and regulatory challenges, showcasing its responsiveness to market dynamics.
See More
Thermo Fisher CEO Sells 10,000 Shares
- Executive Sell-off: Marc N Casper, Chairman and CEO of Thermo Fisher, sold 10,000 shares on March 3, 2026, which may raise market concerns about the company's future performance, as executive sell-offs are often viewed as negative signals regarding company outlook.
- Market Reaction: Such sell-off actions could lead to a decline in investor confidence in Thermo Fisher, potentially impacting its stock performance, especially in the current market environment where investors are particularly sensitive to executive signals.
- Shareholding Structure Change: This transaction may alter Casper's ownership percentage, further influencing market perceptions of management stability, particularly as the company faces increasing competition.
- Strategic Implications: While the sell-off may be interpreted as a negative signal, it could also be part of the executive's personal financial planning, prompting investors to focus on the company's future performance and strategic direction to assess its long-term investment value.
See More
