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CALC Should I Buy

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Intellectia

Should You Buy CalciMedica Inc (CALC) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
0.660
1 Day change
9.78%
52 Week Range
7.200
Analysis Updated At
2026/04/17
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CalciMedica Inc (CALC) is not a strong buy at this time for a beginner investor with a long-term strategy. The stock lacks positive catalysts, has weak financial performance, and no significant trading signals or recent news to support a bullish case. Given the investor's profile and the current market conditions, holding off on investing in this stock is advisable.

Technical Analysis

The MACD histogram is positive but contracting, indicating weakening momentum. RSI is neutral at 44.973, showing no clear overbought or oversold conditions. Moving averages are converging, suggesting indecision in price direction. The stock is trading below the pivot point of 0.644, with key support at 0.564 and resistance at 0.725.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
6
Buy
6

Positive Catalysts

  • Oppenheimer maintains an Outperform rating and highlights a $200M opportunity in acute pancreatitis (AP) despite the discontinuation of the Phase 2 KOURAGE trial.

Neutral/Negative Catalysts

  • The discontinuation of the Phase 2 KOURAGE trial in acute kidney injury (AKI) removes a major catalyst for the stock. Financials show no revenue growth, and net income remains deeply negative. Analysts have lowered price targets, and there is no recent news or significant trading activity to support upward momentum.

Financial Performance

In Q4 2025, the company reported no revenue growth (0% YoY) and a net income of -$10.76M, which improved by 152.70% YoY but remains negative. EPS improved to -0.68, up 106.06% YoY, but still reflects losses. Gross margin remains at 0%.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Mixed analyst sentiment. Oppenheimer lowered the price target from $20 to $10 but maintains an Outperform rating, citing potential in AP. H.C. Wainwright downgraded the stock to Neutral, citing the loss of a major catalyst with the KOURAGE trial discontinuation.

Wall Street analysts forecast CALC stock price to rise
1 Analyst Rating
Wall Street analysts forecast CALC stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.603
sliders
Low
20
Averages
20
High
20
Current: 0.603
sliders
Low
20
Averages
20
High
20
Oppenheimer
Oppenheimer
Outperform
downgrade
$20 -> $10
AI Analysis
2026-03-05
Reason
Oppenheimer
Oppenheimer
Price Target
$20 -> $10
AI Analysis
2026-03-05
downgrade
Outperform
Reason
Oppenheimer lowered the firm's price target on CalciMedica to $10 from $20 and keeps an Outperform rating on the shares. The firm notes CalciMedica reported updates to its programs in acute kidney injury and acute pancreatitis along with quarterly financials. The most important development is the absence of any drug-related toxicity following thorough internal/external review of the unblinded Phase 2 KOURAGE dataset - as CalciMedica had indicated after voluntarily discontinuing the trial in late January.
H.C. Wainwright
H.C. Wainwright
Buy -> Neutral
downgrade
2026-01-29
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
2026-01-29
downgrade
Buy -> Neutral
Reason
H.C. Wainwright downgraded CalciMedica to Neutral from Buy without a price target. The immediate discontinuation for the Phase 2 KOURAGE clinical trial in acute kidney injury removes a major catalyst for the shares, the analyst tells investors in a research note. The firm looks to upcoming safety and population clarity as the company reviews the unblinded dataset to determine a potential path forward.
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