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CALC Should I Buy

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Intellectia

Should You Buy CalciMedica Inc (CALC) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
0.680
1 Day change
-7.66%
52 Week Range
7.200
Analysis Updated At
2026/03/06
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CalciMedica Inc (CALC) is not a strong buy at this time for a beginner investor with a long-term focus. The stock faces significant challenges, including a recent clinical trial discontinuation, weak financials, and limited positive catalysts. While there is some potential upside in the long term, the risks outweigh the rewards for this investor profile.

Technical Analysis

The MACD is positive and expanding, indicating some bullish momentum. However, the RSI is neutral, and the moving averages are bearish (SMA_200 > SMA_20 > SMA_5). The stock is trading near its resistance level of 0.663, suggesting limited immediate upside.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
8
Buy
3

Positive Catalysts

  • Oppenheimer views the stock as oversold and sees potential in Auxora's $200M opportunity in acute pancreatitis (AP).

Neutral/Negative Catalysts

  • The discontinuation of the Phase 2 KOURAGE clinical trial removes a major growth catalyst. Liquidity concerns persist, with only $13M in cash and short-term investments. Analysts have downgraded the stock, and there is no clear path forward for growth.

Financial Performance

The company reported a FY GAAP EPS of -$1.97, reflecting significant profitability challenges. Q3 2025 financials show no revenue, a net income loss of $7.8M (though improved YoY), and an EPS of -0.52. The company has limited cash reserves, expected to last until Q4 2026.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

H.C. Wainwright downgraded the stock to Neutral due to the clinical trial discontinuation. Oppenheimer maintains an Outperform rating but acknowledges significant risks.

Wall Street analysts forecast CALC stock price to rise
1 Analyst Rating
Wall Street analysts forecast CALC stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.731
sliders
Low
20
Averages
20
High
20
Current: 0.731
sliders
Low
20
Averages
20
High
20
Oppenheimer
Oppenheimer
Outperform
downgrade
$20 -> $10
AI Analysis
2026-03-05
Reason
Oppenheimer
Oppenheimer
Price Target
$20 -> $10
AI Analysis
2026-03-05
downgrade
Outperform
Reason
Oppenheimer lowered the firm's price target on CalciMedica to $10 from $20 and keeps an Outperform rating on the shares. The firm notes CalciMedica reported updates to its programs in acute kidney injury and acute pancreatitis along with quarterly financials. The most important development is the absence of any drug-related toxicity following thorough internal/external review of the unblinded Phase 2 KOURAGE dataset - as CalciMedica had indicated after voluntarily discontinuing the trial in late January.
H.C. Wainwright
H.C. Wainwright
Buy -> Neutral
downgrade
2026-01-29
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
2026-01-29
downgrade
Buy -> Neutral
Reason
H.C. Wainwright downgraded CalciMedica to Neutral from Buy without a price target. The immediate discontinuation for the Phase 2 KOURAGE clinical trial in acute kidney injury removes a major catalyst for the shares, the analyst tells investors in a research note. The firm looks to upcoming safety and population clarity as the company reviews the unblinded dataset to determine a potential path forward.
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