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APRE Should I Buy

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Intellectia

Should You Buy Aprea Therapeutics Inc (APRE) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
0.710
1 Day change
1.72%
52 Week Range
2.340
Analysis Updated At
2026/04/02
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Aprea Therapeutics Inc (APRE) is not a strong buy at this time for a beginner investor with a long-term focus. The stock's technical indicators are bearish, financial performance is weak, and the recent financing dilution has negatively impacted the stock's outlook. While there are some positive catalysts, such as insider buying and promising clinical developments, the overall sentiment and performance do not align with a strong buy recommendation.

Technical Analysis

The technical indicators for APRE are bearish. The MACD is below zero and contracting negatively, RSI is neutral at 46.921, and the moving averages show a bearish trend (SMA_200 > SMA_20 > SMA_5). The stock is trading below key pivot levels, with support at 0.626 and resistance at 0.705.

Positive Catalysts

  • Insider buying has increased by 147.37% in the last month.

  • The company raised $30 million in oversubscribed financing, extending its cash runway into early

  • Promising clinical developments, including partial response in Phase 1 trials for APR-1051.

Neutral/Negative Catalysts

  • Significant dilution from recent financing through pre-funded warrants and common share warrants.

  • Analysts have consistently lowered price targets, citing dilution concerns.

  • Weak trading trends with hedge funds remaining neutral and no significant trading activity.

Financial Performance

The company's financial performance in Q4 2025 is weak. Revenue dropped by 98.38% YoY to 3337. Net income fell by 15.17% YoY to -2,455,630. EPS declined by 34.69% YoY to -0.32. Gross margin remained flat at 100%.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts maintain a Buy or Outperform rating but have significantly lowered price targets due to dilution concerns. H.C. Wainwright reduced the price target from $4 to $1.20, and Wedbush reduced it from $11 to $7.

Wall Street analysts forecast APRE stock price to rise
3 Analyst Rating
Wall Street analysts forecast APRE stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.699
sliders
Low
4
Averages
5.33
High
7
Current: 0.699
sliders
Low
4
Averages
5.33
High
7
H.C. Wainwright
H.C. Wainwright
Buy
downgrade
$4
AI Analysis
2026-03-31
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$4
AI Analysis
2026-03-31
downgrade
Buy
Reason
H.C. Wainwright lowered the firm's price target on Aprea Therapeutics to $1.20 from $4 and keeps a Buy rating on the shares. The firm cites the "significant dilution" from yesterday's financing through pre-funded warrants and warrant to buy common shares for the target cut.
Wedbush
Outperform -> NULL
downgrade
$11 -> $7
2026-02-10
Reason
Wedbush
Price Target
$11 -> $7
2026-02-10
downgrade
Outperform -> NULL
Reason
Wedbush lowered the firm's price target on Aprea Therapeutics to $7 from $11 and keeps an Outperform rating on the shares. The firm notes the company announced preliminary proof-of-concept data for WEE1 inhibitor APR-1051. Wedbush believes the recent partial response is further validating of the clinical potential for APR-1051, and the firm expects to continue to see dose responses as higher dosing cohorts are enrolled.
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