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ZVRA Should I Buy

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Intellectia

Should You Buy Zevra Therapeutics Inc (ZVRA) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
8.780
1 Day change
-4.15%
52 Week Range
13.160
Analysis Updated At
2026/03/27
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Zevra Therapeutics Inc (ZVRA) is not a strong buy at this moment for a beginner investor with a long-term focus. While the company has positive catalysts such as strong analyst ratings and potential growth opportunities, the technical indicators and insider selling trends suggest caution. Additionally, the financial performance shows a mixed picture with revenue growth but significant drops in net income and EPS. For now, holding off on buying is recommended until clearer positive signals emerge.

Technical Analysis

The MACD histogram is negative and contracting (-0.0813), indicating bearish momentum. RSI is neutral at 44.63, and moving averages are converging, showing no clear trend. The stock is trading near its support level (S1: 9.076) but below the pivot (9.721), suggesting limited upward momentum in the short term.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

The open interest put-call ratio of 0.93 indicates a balanced sentiment, while the option volume put-call ratio of 0.42 leans bullish. However, implied volatility is high at 102.12, suggesting elevated risk.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
11
Buy
5

Positive Catalysts

  • Analyst ratings are consistently positive with price targets significantly above the current price ($23-$26). Potential catalysts include Miplyffa's continued market penetration, EU approval, and patent term extensions. Revenue growth of 183.36% YoY in Q4 2025 is also a positive sign.

Neutral/Negative Catalysts

  • Insiders are selling heavily, with an 809.12% increase in selling activity over the last month. Net income and EPS have dropped significantly (-133.10% and -129.85% YoY, respectively), raising concerns about profitability. Technical indicators do not show strong bullish momentum.

Financial Performance

In Q4 2025, revenue increased by 183.36% YoY to $34.13M, showing strong top-line growth. However, net income dropped by -133.10% YoY to $11.83M, and EPS fell by -129.85% YoY to 0.2, indicating profitability challenges. Gross margin improved to 94.62%, up 25.76% YoY.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are bullish on ZVRA, with multiple Buy ratings and price targets ranging from $23 to $26. Analysts highlight strong growth potential for Miplyffa and other pipeline opportunities, suggesting significant upside potential.

Wall Street analysts forecast ZVRA stock price to rise
6 Analyst Rating
Wall Street analysts forecast ZVRA stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 9.160
sliders
Low
21
Averages
24
High
26
Current: 9.160
sliders
Low
21
Averages
24
High
26
BTIG
Kambiz Yazdi
Buy
initiated
$23
AI Analysis
2026-03-16
Reason
BTIG
Kambiz Yazdi
Price Target
$23
AI Analysis
2026-03-16
initiated
Buy
Reason
BTIG analyst Kambiz Yazdi initiated coverage of Zevra Therapeutics with a Buy rating and $23 price target. Zevra's current valuation appears to reflect conservative adoption of Miplyffa limited to the existing U.S. diagnosed NPC population, establishing a downside floor based on that cohort, the analyst tells investors in a research note. Upside catalysts in 2026 include expansion of newly diagnosed U.S. patients, potential EU approval, patent term extension to lengthen exclusivity, and optionality from accelerating celiprolol development in VEDS, the firm says.
Guggenheim
Buy
maintain
$22 -> $23
2026-03-10
Reason
Guggenheim
Price Target
$22 -> $23
2026-03-10
maintain
Buy
Reason
Guggenheim raised the firm's price target on Zevra Therapeutics to $23 from $22 and keeps a Buy rating on the shares. Miplyffa's launch continues to perform well, with FY25 results showing "a clear acceleration," says the analyst, who expects steady growth to continue as Miplyffa further penetrates the U.S. market and retention remains high.
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