Should I Buy XLO? XLO 2026 Analysis

Should You Buy Xilio Therapeutics Inc (XLO) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion

Hold

Latest Price

0.600

1 Day change

-2.10%

52 Week Range

1.700

Analysis Updated At

2026/01/26

Xilio Therapeutics Inc (XLO) is not a strong buy at the moment for a beginner, long-term investor with $50,000-$100,000 available for investment. The technical indicators are bearish, there are no significant trading trends or positive news catalysts, and the stock is expected to decline in the short term. While the company has shown impressive revenue growth in the latest quarter, its negative net income, declining EPS, and lack of clear positive sentiment make it a hold rather than a buy.

Technical Analysis

The MACD is below 0 and negatively contracting, indicating bearish momentum. The RSI is neutral at 43.007, and the moving averages are bearish (SMA_200 > SMA_20 > SMA_5). The stock is trading below its pivot point of 0.651, with support at 0.587 and resistance at 0.715. Overall, the technical indicators suggest a bearish trend.

Options Data

Positive Catalysts

Revenue increased significantly by 742.51% YoY in the latest quarter, and gross margin remains strong at 100%.

Neutral/Negative Catalysts

The stock is expected to decline by -5.68% in the next week and -5.3% in the next month. EPS dropped by -50.00% YoY, and net income remains negative at -$16.29M. No significant trading trends, news, or recent congress trading data are available to support a positive sentiment.

Financial Performance

In Q3 2025, revenue increased significantly to $19.07M (up 742.51% YoY), but net income remains negative at -$16.29M (up 16.17% YoY). EPS dropped to -0.11 (down -50.00% YoY), and gross margin remains strong at 100%.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

No recent analyst rating or price target changes are available.

Analyst Rating

Wall Street analysts forecast XLO stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for XLO is 0 USD with a low forecast of 0 USD and a high forecast of 0 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

Buy

Hold

Sell

Current: 0.618

Low

Averages

High

Current: 0.618

Low

Averages

High

Leerink

Outperform

initiated

$72

AI Analysis

2025-08-06

Reason