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XFOR Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

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High
4.030
Open
3.900
VWAP
3.95
Vol
67.19K
Mkt Cap
112.53M
Low
3.880
Amount
265.42K
EV/EBITDA(TTM)
--
Total Shares
--
EV
4.54M
EV/OCF(TTM)
--
P/S(TTM)
--
X4 Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on discovering and developing novel therapeutics for the treatment of rare diseases and those with limited treatment options, with a focus on conditions resulting from dysfunction of the immune system. Its lead clinical candidate is mavorixafor, a small-molecule selective antagonist of chemokine receptor CXCR4. It has developed a small-molecule, oral antagonists of the chemokine receptor C-X-C receptor type 4 (CXCR4). It has two pre-clinical candidates: X4P-003, a second-generation CXCR4 antagonist designed to have enhanced properties relative to mavorixafor, potentially enabling opportunities in CXCR4-dependent disorders and primary immunodeficiencies, and X4P-002, a CXCR4 antagonist with a distribution profile and a demonstrated ability to cross the blood-brain barrier.
Show More

Events Timeline

(ET)
2026-02-27
07:10:00
X4 Pharmaceuticals Receives Positive Opinion for Mavorixafor in EU
select
2025-11-05 (ET)
2025-11-05
07:04:20
X4 Pharmaceuticals announces Q3 earnings per share of 69 cents, below consensus estimate of 84 cents.
select
2025-10-24 (ET)
2025-10-24
06:35:24
X4 Pharmaceuticals Prices 45.87M Share Spot Secondary Offering at $2.85
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2025-10-23 (ET)
2025-10-23
16:03:05
X4 Pharmaceuticals Reveals Common Stock Offering, Amount Not Disclosed
select
2025-09-29 (ET)
2025-09-29
07:38:56
Altimmune Names Christophe Arbet-Engels as Chief Medical Officer
select

News

NASDAQ.COM
9.0
02-27NASDAQ.COM
X4 Pharmaceuticals Receives Positive EMA Opinion for Mavorixafor
  • Regulatory Progress: X4 Pharmaceuticals announced that the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion for mavorixafor to treat WHIM syndrome, with a decision from the European Commission expected in Q2 2026, potentially opening significant market opportunities for the company.
  • Clinical Trial Results: This positive opinion is supported by favorable outcomes from a pivotal Phase 3 trial assessing the efficacy and safety of XOLREMDI in patients aged 12 and older with WHIM syndrome, demonstrating strong clinical effectiveness and enhancing the drug's market outlook.
  • Commercial Partnership Agreement: In January 2025, X4 entered into a licensing and supply agreement with Norgine, which will commercialize mavorixafor in Europe, Australia, and New Zealand following regulatory approvals, potentially generating up to $226 million in regulatory and commercial milestone payments for X4.
  • Future Revenue Potential: X4 is also eligible for escalating double-digit royalties of up to the mid-twenties percentage on future net sales, providing a stable revenue stream and enhancing its competitive position in the global market.
Newsfilter
8.5
02-27Newsfilter
X4 Pharmaceuticals Receives Positive Opinion for WHIM Syndrome Therapy in EU
  • Regulatory Milestone: X4 Pharmaceuticals' mavorixafor has received a positive opinion from the EMA's CHMP, potentially becoming the first and only therapy for WHIM syndrome in the EU, addressing a significant unmet medical need for patients with this ultra-rare disease.
  • Clinical Trial Success: The 4WHIM trial demonstrated that mavorixafor significantly increased absolute neutrophil counts (ANC) and absolute lymphocyte counts (ALC), with threshold time improvements compared to placebo and a 60% reduction in infection rates, showcasing its remarkable efficacy.
  • Commercial Partnership Agreement: X4 entered into a licensing and supply agreement with Norgine, which will commercialize mavorixafor in Europe, Australia, and New Zealand, allowing X4 to receive up to €226 million in milestone payments and double-digit royalties on future sales, enhancing the company's revenue potential.
  • Market Access Strategy: X4 plans to collaborate with Norgine to ensure timely patient access to this critical treatment following final approval, further solidifying its market position in the rare disease sector.
Benzinga
8.5
2025-12-24Benzinga
Sanofi Acquires Dynavax for $15.50 per Share, Totaling $2.2 Billion
  • Acquisition Deal: Sanofi's agreement to acquire Dynavax for $15.50 per share, totaling approximately $2.2 billion, is expected to enhance its market presence in adult immunization, potentially driving future revenue growth.
  • Stock Price Reaction: Following the acquisition announcement, Dynavax shares surged 38.6% to $15.44, indicating a positive market response that may attract further investor interest in the company.
  • FDA Approval Impact: Omeros Corp's stock jumped 66.8% to $14.60 after the FDA approved YARTEMLEA for treating related conditions, reflecting strong market demand and optimistic expectations for potential revenues from new drugs.
  • Market Dynamics: Companies like Edgewise Therapeutics and Agios Pharmaceuticals also saw significant stock price increases due to positive clinical trial results and FDA approvals, indicating a resurgence of activity and investor confidence in the biotech sector.
Yahoo Finance
8.5
2025-11-24Yahoo Finance
Examining X4 Pharmaceuticals' Story Following Leadership Transitions and Recent Funding
  • Analyst Price Target Adjustments: X4 Pharmaceuticals' consensus analyst price target has decreased from $8.70 to $7.38 due to updated financing scenarios and changes in leadership, reflecting a more cautious outlook on expected returns.

  • Bullish and Bearish Perspectives: While Stifel maintains a Buy rating despite lowering its price target, indicating confidence in the company's long-term prospects, there are concerns about valuation and the impact of recent recapitalizations on shareholders.

  • Capital Raise and Strategic Restructuring: The company raised $135 million through a follow-on equity offering and announced a workforce reduction of about 50% to focus on key development initiatives, aiming for significant cost savings.

  • Financial Metrics Overview: Key financial metrics have been adjusted, with revenue growth expectations lowered and net profit margins increased, suggesting improved profitability despite slower sales expansion.

NASDAQ.COM
5.0
2025-10-28NASDAQ.COM
Insider Buying Update for Tuesday, October 28: CRMD and XFOR
  • CorMedix Insider Purchase: Myron Kaplan, Director of CorMedix, purchased 25,000 shares at $11.02 each for a total of $275,500, marking his first buy in the past year, and is currently up 7.4% based on today's trading high.

  • X4 Pharmaceuticals Insider Purchase: Adam R. Craig, Executive Chairman of X4 Pharmaceuticals, bought 86,206 shares at $2.90 each for a total of $249,997, and is up 36.6% based on today's trading high.

  • Market Performance: CorMedix shares are up about 2.5% on Tuesday, while X4 Pharmaceuticals shares have increased by approximately 0.7%.

  • Disclaimer: The views expressed in the report are those of the author and do not necessarily reflect the opinions of Nasdaq, Inc.

NASDAQ.COM
9.5
2025-10-28NASDAQ.COM
Healthcare Rally: Pulmonx, UHS, and X4 Experience After-Hours Gains Following Strategic Announcements
  • Pulmonx Corp. Performance: Pulmonx Corp. saw a significant increase of 33.33% to $2.08 after announcing preliminary Q3 2025 revenue of approximately $21.5 million and leadership changes, including the reappointment of Glen French as President and CEO.

  • Q32 Bio Inc. Gains: Q32 Bio Inc. experienced a 12.5% rise to $3.15 in after-hours trading, although no specific news was reported to explain this increase.

  • Universal Health Services Update: Universal Health Services Inc. climbed 7.41% to $229.90 following its Q3 results and a revised full-year forecast, along with a $1.5 billion increase in its stock repurchase program.

  • X4 Pharmaceuticals Offering: X4 Pharmaceuticals Inc. gained 5.35% to $3.94 after completing a public offering of 52.8 million shares, raising approximately $155.3 million before expenses, increasing total shares outstanding to 79.2 million.

Wall Street analysts forecast XFOR stock price to rise
4 Analyst Rating
Wall Street analysts forecast XFOR stock price to rise
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
7.00
Averages
57.75
High
120.00
Current: 0.000
sliders
Low
7.00
Averages
57.75
High
120.00
Guggenheim
NULL -> Buy
initiated
$12
AI Analysis
2026-03-09
New
Reason
Guggenheim
Price Target
$12
AI Analysis
2026-03-09
New
initiated
NULL -> Buy
Reason
Guggenheim initiated coverage of X4 Pharmaceuticals with a Buy rating and $12 price target. The firm sees the "differentiated hematology play" having significant upside potential in the next 18 months with a current valuation that does not fully reflect the opportunity of the company's "key value driver," mavorixafor, a potential first-in-class oral CXCR4 antagonist for WHIM syndrome, an already approved ultra-rare condition, and potentially in primary chronic neutropenia, for which it is in Phase 3 development.
Stifel
James Condulis
NULL -> Buy
maintain
$10
2025-12-05
Reason
Stifel
James Condulis
Price Target
$10
2025-12-05
maintain
NULL -> Buy
Reason
Stifel analyst James Condulis raised the firm's price target on X4 Pharmaceuticals to $10 from $7.50 and keeps a Buy rating on the shares as the firm transferred coverage of the stock. The firm's "bullish thesis" is based on a view that, after a significant transformation of the company in recent months, X4 "finally has the right team" to develop, launch and sell a hematology-focused asset and necessary capital and strategy through a potential launch in 2028, the new analyst tells investors.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for XFOR
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Valuation Metrics

The current forward P/E ratio for X4 Pharmaceuticals Inc (XFOR.O) is -0.52, compared to its 5-year average forward P/E of -1.95. For a more detailed relative valuation and DCF analysis to assess X4 Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.95
Current PE
-0.52
Overvalued PE
-0.41
Undervalued PE
-3.48

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
127.84
Current PS
3.52
Overvalued PS
382.72
Undervalued PS
-127.05

Financials

AI Analysis
Annual
Quarterly

Whales Holding XFOR

P
Perceptive Advisors LLC
Holding
XFOR
+3.06%
3M Return
B
BVF Partners L.P.
Holding
XFOR
+1.32%
3M Return
N
New Enterprise Associates, Inc.
Holding
XFOR
-2.87%
3M Return

Trading Trends

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Frequently Asked Questions

What is X4 Pharmaceuticals Inc (XFOR) stock price today?

The current price of XFOR is 3.94 USD — it has increased 1.55

What is X4 Pharmaceuticals Inc (XFOR)'s business?

X4 Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on discovering and developing novel therapeutics for the treatment of rare diseases and those with limited treatment options, with a focus on conditions resulting from dysfunction of the immune system. Its lead clinical candidate is mavorixafor, a small-molecule selective antagonist of chemokine receptor CXCR4. It has developed a small-molecule, oral antagonists of the chemokine receptor C-X-C receptor type 4 (CXCR4). It has two pre-clinical candidates: X4P-003, a second-generation CXCR4 antagonist designed to have enhanced properties relative to mavorixafor, potentially enabling opportunities in CXCR4-dependent disorders and primary immunodeficiencies, and X4P-002, a CXCR4 antagonist with a distribution profile and a demonstrated ability to cross the blood-brain barrier.

What is the price predicton of XFOR Stock?

Wall Street analysts forecast XFOR stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for XFOR is57.75 USD with a low forecast of 7.00 USD and a high forecast of 120.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is X4 Pharmaceuticals Inc (XFOR)'s revenue for the last quarter?

X4 Pharmaceuticals Inc revenue for the last quarter amounts to 28.81M USD, decreased

What is X4 Pharmaceuticals Inc (XFOR)'s earnings per share (EPS) for the last quarter?

X4 Pharmaceuticals Inc. EPS for the last quarter amounts to 1.20 USD, decreased -115.44

How many employees does X4 Pharmaceuticals Inc (XFOR). have?

X4 Pharmaceuticals Inc (XFOR) has 143 emplpoyees as of March 13 2026.

What is X4 Pharmaceuticals Inc (XFOR) market cap?

Today XFOR has the market capitalization of 112.53M USD.