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TLPH Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
0.840
Open
0.826
VWAP
0.82
Vol
186.30K
Mkt Cap
42.35M
Low
0.792
Amount
152.05K
EV/EBITDA(TTM)
--
Total Shares
51.90M
EV
21.53M
EV/OCF(TTM)
--
P/S(TTM)
43.76K
Talphera, Inc. is a specialty pharmaceutical company focused on the development and commercialization of therapies for use in medically supervised settings. The Company’s portfolio consists of nafamostat product candidates and pre-filled syringe product candidates. The Company’s lead product candidate, Niyad, is a lyophilized formulation of nafamostat and is being studied under an investigational device exemption (IDE) as an anticoagulant for the extracorporeal circuit. Niyad is used in adult patients undergoing continuous renal replacement therapy (CRRT). LTX-608 is its nafamostat formulation for direct IV infusion being explored as an investigational product for one or more indications, including antiviral treatment, or treatment of acute respiratory distress syndrome (ARDS) disseminated intravascular coagulation (DIC), or acute pancreatitis. The Company’s two ready-to-use pre-filled syringe (PFS) product candidates include Fedsyra and phenylephrine.
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Events Timeline

(ET)
2026-05-13
16:20:00
Vince Angotti: Nafamostat Study Progressing Well
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2026-03-25 (ET)
2026-03-25
06:10:00
Talphera Files to Sell 639,931 Shares of Common Stock
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2026-03-23 (ET)
2026-03-23
16:40:00
Trump Claims US-Iran Talks Boost Markets
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2026-03-23
12:10:00
Trump Claims US-Iran Talks, Oil Prices Pull Back
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2026-03-23
08:40:00
Talphera Reports Cash and Investments of $20.4M
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2026-03-02 (ET)
2026-03-02
08:40:00
Talphera Achieves 50% Patient Enrollment in NEPHRO-CRRT Clinical Trial
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2025-12-30 (ET)
2025-12-30
08:50:00
PharmaCyte Biotech Borrow Rate Hits 96.86% Among Liquid Options
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2025-11-12 (ET)
2025-11-12
16:15:48
Talphera announces Q3 earnings per share of 11 cents, compared to a loss of 13 cents in the same period last year.
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2025-10-28 (ET)
2025-10-28
16:31:49
Talphera Seeks Approval to Sell 1.02 Million Shares of Common Stock for Shareholders
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News

seekingalpha
9.5
05-14seekingalpha
Talphera Q1 2026 Earnings Call Highlights
  • Clinical Trial Progress: Talphera has achieved 50% enrollment in the NEPHRO study and expects to complete enrollment in 2026, with a PMA filing for Niyad targeted for 2027, indicating significant advancement in key product development.
  • Strong Financial Position: As of March 31, 2026, Talphera reported a cash balance of $21.1 million and closed a $4.1 million financing tranche during the quarter, ensuring sufficient capital ahead of critical milestones.
  • Cost Management: Cash operating expenses for Q1 2026 totaled $3.9 million, up from $2.9 million in Q1 2025, primarily due to increased Niyad development costs, reflecting the company's ongoing investment in R&D.
  • Future Outlook: Management expresses optimism for top line data release in the second half of 2026, anticipating results to be announced within a month after the last patient exits, further bolstering market confidence in the company's future growth.
seekingalpha
9.5
05-13seekingalpha
Talphera Reports Q1 EPS Beat with Increased R&D Spending
  • Earnings Performance: Talphera's Q1 GAAP EPS of -$0.04 beats expectations by $0.04, indicating a slight improvement in financial performance despite remaining in a loss position.
  • Cash Position: As of March 31, 2026, the company's cash and investments balance stood at $21.1 million, ensuring sufficient funding for future R&D and operations, thereby boosting investor confidence.
  • Expense Increase: Combined R&D and SG&A expenses for Q1 2026 totaled $3.9 million, significantly up from $2.9 million in Q1 2025, primarily driven by higher Niyad® development costs, reflecting the company's ongoing commitment to new product development.
  • Impact of Non-Cash Expenses: Excluding non-cash stock-based compensation, expenses for Q1 2026 were $3.7 million compared to $2.7 million in 2025, indicating operational cost pressures that may affect future profitability.
seekingalpha
9.5
05-12seekingalpha
Talphera Scheduled to Announce Q1 Earnings on May 13
  • Earnings Announcement: Talphera (TLPH) is set to release its Q1 earnings on May 13 after market close, with a consensus EPS estimate of -$0.08, indicating ongoing challenges in profitability.
  • Historical Performance: Over the past year, Talphera has beaten EPS estimates 75% of the time, reflecting relative stability in earnings forecasts, although the revenue beat rate stands at only 25%, suggesting a need for stronger revenue growth.
  • Recent Revisions: In the last three months, Talphera's EPS estimates have seen one upward revision with no downward adjustments, indicating increased analyst confidence in the company's future performance, which could positively impact its stock price.
  • Investor Focus: As the earnings report approaches, investors and analysts will closely monitor Talphera's financial data to assess its performance and growth potential in a competitive market environment.
PRnewswire
8.5
03-25PRnewswire
Talphera Announces Acceptance of Two Abstracts at International Conference on Advances in Critical Care Nephrology
  • Abstract Acceptance: Talphera announced that two of its research abstracts have been accepted for presentation at the 2026 International Conference on Advances in Critical Care Nephrology, showcasing its innovative research in the CRRT field, which may enhance the company's reputation and influence in the medical sector.
  • NEPHRO-CRRT Study: This study aims to evaluate the safety and efficacy of Niyad in patients who cannot tolerate heparin, planning to enroll 70 patients across 14 U.S. hospitals; if successful, it will address a significant unmet medical need in the CRRT domain.
  • Nafamostat's Potential: Research indicates that nafamostat exhibits unique pharmacokinetic properties in a porcine model, effectively controlling systemic activated clotting time; if approved by the FDA, it will become the first regional anticoagulant for CRRT, presenting substantial market opportunities.
  • Innovative Drug Development: Talphera's Niyad, a lyophilized formulation of nafamostat, has received Breakthrough Device Designation from the FDA, and if successfully commercialized, it will provide significant business opportunities and competitive advantages for the company.
Newsfilter
8.5
03-25Newsfilter
Talphera Presents Innovative Therapies at International Conference
  • Research Presentation: Talphera will showcase two studies on Niyad and Nafamostat at the AKI & CRRT 2026 conference from March 29 to April 2, highlighting their potential applications in CRRT, which could transform the current anticoagulant landscape.
  • NEPHRO-CRRT Study Progress: The study is enrolling 70 adult patients who cannot tolerate heparin or are at risk of bleeding, primarily assessing the mean post-filter activated clotting time of Niyad versus placebo over the first 24 hours, potentially paving the way for FDA approval.
  • Drug Characteristics Analysis: Nafamostat has over three decades of usage experience in Japan and South Korea, and its unique pharmacokinetic and pharmacodynamic properties make it an ideal candidate for regional anticoagulation in CRRT, filling a significant market gap if approved.
  • Clinical Application Outlook: Talphera's Niyad has received FDA Breakthrough Device Designation, and if successfully launched, it will become the first regional anticoagulant approved for use in CRRT, expected to significantly enhance patient treatment outcomes and safety.
seekingalpha
9.5
03-23seekingalpha
Talphera Reports Q4 2025 Earnings with EPS of -$0.06
  • Earnings Highlights: Talphera's Q4 2025 GAAP EPS of -$0.06 beats expectations by $0.01, indicating a slight improvement in financial performance despite still being in the red.
  • Cash Position: As of December 31, 2025, Talphera reported a cash and investments balance of $20.4 million, providing a financial cushion for future operations and R&D initiatives.
  • Rising Expense Forecast: Cash operating expenses for 2026 are projected to range between $17 million and $18 million, up from approximately $13 million in 2025, primarily driven by the NEPHRO CRRT study and associated costs.
  • Clinical Trial Progress: The increase in expenses also includes costs related to finalizing the NEPHRO CRRT registration trial, expected to be completed later this year, marking a significant step towards filing for Premarket Approval with the FDA.
Wall Street analysts forecast TLPH stock price to rise
2 Analyst Rating
Wall Street analysts forecast TLPH stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
3.00
Averages
3.25
High
3.50
Current: 0.000
sliders
Low
3.00
Averages
3.25
High
3.50
WestPark Capital
Ed Arce
initiated
$3
AI Analysis
2026-04-30
Reason
WestPark Capital
Ed Arce
Price Target
$3
AI Analysis
2026-04-30
initiated
Reason
WestPark Capital analyst Ed Arce initiated coverage of Talphera with a Buy rating and $3 price target. The firm says the company is brining the best continuous renal replacement therapy anticoagulant in the U.S. with data expected by the end of 2026.

Valuation Metrics

The current forward P/E ratio for Talphera Inc (TLPH.O) is 1.02, compared to its 5-year average forward P/E of -1.67. For a more detailed relative valuation and DCF analysis to assess Talphera Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.67
Current PE
1.02
Overvalued PE
0.81
Undervalued PE
-4.14

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.45
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
1.04
Undervalued EV/EBITDA
-1.94

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
484.62
Current PS
0.00
Overvalued PS
2300.43
Undervalued PS
-1331.19

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Frequently Asked Questions

What is Talphera Inc (TLPH) stock price today?

The current price of TLPH is 0.816 USD — it has decreased -0.73

What is Talphera Inc (TLPH)'s business?

Talphera, Inc. is a specialty pharmaceutical company focused on the development and commercialization of therapies for use in medically supervised settings. The Company’s portfolio consists of nafamostat product candidates and pre-filled syringe product candidates. The Company’s lead product candidate, Niyad, is a lyophilized formulation of nafamostat and is being studied under an investigational device exemption (IDE) as an anticoagulant for the extracorporeal circuit. Niyad is used in adult patients undergoing continuous renal replacement therapy (CRRT). LTX-608 is its nafamostat formulation for direct IV infusion being explored as an investigational product for one or more indications, including antiviral treatment, or treatment of acute respiratory distress syndrome (ARDS) disseminated intravascular coagulation (DIC), or acute pancreatitis. The Company’s two ready-to-use pre-filled syringe (PFS) product candidates include Fedsyra and phenylephrine.

What is the price predicton of TLPH Stock?

Wall Street analysts forecast TLPH stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for TLPH is3.25 USD with a low forecast of 3.00 USD and a high forecast of 3.50 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Talphera Inc (TLPH)'s revenue for the last quarter?

Talphera Inc revenue for the last quarter amounts to 0.00 USD, decreased -100.00

What is Talphera Inc (TLPH)'s earnings per share (EPS) for the last quarter?

Talphera Inc. EPS for the last quarter amounts to -0.04 USD, decreased -60.00

How many employees does Talphera Inc (TLPH). have?

Talphera Inc (TLPH) has 12 emplpoyees as of May 31 2026.

What is Talphera Inc (TLPH) market cap?

Today TLPH has the market capitalization of 42.35M USD.