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TLPH Overview

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0.000(0.000%)Aft-market
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0.000
0.000(0.000%)
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Intellectia

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High
0.761
Open
0.761
VWAP
0.74
Vol
131.21K
Mkt Cap
37.33M
Low
0.712
Amount
97.06K
EV/EBITDA(TTM)
--
Total Shares
50.05M
EV
16.95M
EV/OCF(TTM)
--
P/S(TTM)
1.13K
Talphera, Inc. is a specialty pharmaceutical company focused on the development and commercialization of therapies for use in medically supervised settings. The Company’s portfolio consists of nafamostat product candidates and pre-filled syringe product candidates. The Company’s lead product candidate, Niyad, is a lyophilized formulation of nafamostat and is being studied under an investigational device exemption (IDE) as an anticoagulant for the extracorporeal circuit. Niyad is used in adult patients undergoing continuous renal replacement therapy (CRRT). LTX-608 is its nafamostat formulation for direct IV infusion being explored as an investigational product for one or more indications, including antiviral treatment, or treatment of acute respiratory distress syndrome (ARDS) disseminated intravascular coagulation (DIC), or acute pancreatitis. The Company’s two ready-to-use pre-filled syringe (PFS) product candidates include Fedsyra and phenylephrine.
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Events Timeline

(ET)
2026-03-25
06:10:00
Talphera Files to Sell 639,931 Shares of Common Stock
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2026-03-23 (ET)
2026-03-23
16:40:00
Trump Claims US-Iran Talks Boost Markets
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2026-03-23
12:10:00
Trump Claims US-Iran Talks, Oil Prices Pull Back
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2026-03-23
08:40:00
Talphera Reports Cash and Investments of $20.4M
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2026-03-02 (ET)
2026-03-02
08:40:00
Talphera Achieves 50% Patient Enrollment in NEPHRO-CRRT Clinical Trial
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2025-12-30 (ET)
2025-12-30
08:50:00
PharmaCyte Biotech Borrow Rate Hits 96.86% Among Liquid Options
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2025-11-12 (ET)
2025-11-12
16:15:48
Talphera announces Q3 earnings per share of 11 cents, compared to a loss of 13 cents in the same period last year.
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2025-10-28 (ET)
2025-10-28
16:31:49
Talphera Seeks Approval to Sell 1.02 Million Shares of Common Stock for Shareholders
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2025-09-22 (ET)
2025-09-22
17:13:15
Talphera Seeks Approval to Sell 25.04 Million Shares of Common Stock for Shareholders
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2025-09-08 (ET)
2025-09-08
08:40:06
CorMedix Invests $5M in Minority Equity Stake in Talphera
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News

PRnewswire
8.5
03-25PRnewswire
Talphera Announces Acceptance of Two Abstracts at International Conference on Advances in Critical Care Nephrology
  • Abstract Acceptance: Talphera announced that two of its research abstracts have been accepted for presentation at the 2026 International Conference on Advances in Critical Care Nephrology, showcasing its innovative research in the CRRT field, which may enhance the company's reputation and influence in the medical sector.
  • NEPHRO-CRRT Study: This study aims to evaluate the safety and efficacy of Niyad in patients who cannot tolerate heparin, planning to enroll 70 patients across 14 U.S. hospitals; if successful, it will address a significant unmet medical need in the CRRT domain.
  • Nafamostat's Potential: Research indicates that nafamostat exhibits unique pharmacokinetic properties in a porcine model, effectively controlling systemic activated clotting time; if approved by the FDA, it will become the first regional anticoagulant for CRRT, presenting substantial market opportunities.
  • Innovative Drug Development: Talphera's Niyad, a lyophilized formulation of nafamostat, has received Breakthrough Device Designation from the FDA, and if successfully commercialized, it will provide significant business opportunities and competitive advantages for the company.
Newsfilter
8.5
03-25Newsfilter
Talphera Presents Innovative Therapies at International Conference
  • Research Presentation: Talphera will showcase two studies on Niyad and Nafamostat at the AKI & CRRT 2026 conference from March 29 to April 2, highlighting their potential applications in CRRT, which could transform the current anticoagulant landscape.
  • NEPHRO-CRRT Study Progress: The study is enrolling 70 adult patients who cannot tolerate heparin or are at risk of bleeding, primarily assessing the mean post-filter activated clotting time of Niyad versus placebo over the first 24 hours, potentially paving the way for FDA approval.
  • Drug Characteristics Analysis: Nafamostat has over three decades of usage experience in Japan and South Korea, and its unique pharmacokinetic and pharmacodynamic properties make it an ideal candidate for regional anticoagulation in CRRT, filling a significant market gap if approved.
  • Clinical Application Outlook: Talphera's Niyad has received FDA Breakthrough Device Designation, and if successfully launched, it will become the first regional anticoagulant approved for use in CRRT, expected to significantly enhance patient treatment outcomes and safety.
seekingalpha
9.5
03-23seekingalpha
Talphera Reports Q4 2025 Earnings with EPS of -$0.06
  • Earnings Highlights: Talphera's Q4 2025 GAAP EPS of -$0.06 beats expectations by $0.01, indicating a slight improvement in financial performance despite still being in the red.
  • Cash Position: As of December 31, 2025, Talphera reported a cash and investments balance of $20.4 million, providing a financial cushion for future operations and R&D initiatives.
  • Rising Expense Forecast: Cash operating expenses for 2026 are projected to range between $17 million and $18 million, up from approximately $13 million in 2025, primarily driven by the NEPHRO CRRT study and associated costs.
  • Clinical Trial Progress: The increase in expenses also includes costs related to finalizing the NEPHRO CRRT registration trial, expected to be completed later this year, marking a significant step towards filing for Premarket Approval with the FDA.
PRnewswire
9.5
03-23PRnewswire
Talphera Reports 2025 Financial Results and Clinical Progress
  • Clinical Study Progress: Talphera announced that the NEPHRO CRRT clinical study has achieved 50% enrollment, with expected completion in 2026, indicating positive advancements in drug development that may pave the way for future market launches.
  • Successful Financing: The company successfully closed a $4.1 million financing tranche, strengthening its financial position and providing robust funding support for upcoming clinical trials and product development, thereby boosting investor confidence.
  • Financial Status Update: As of December 31, 2025, Talphera reported $20.4 million in cash and investments, reflecting financial stability in operations and ensuring continued support for ongoing R&D activities.
  • Investor Day Event: Talphera will host a virtual Investor and Analyst Day on March 23, 2026, expected to share more business updates and the latest progress on clinical studies, further enhancing engagement and transparency with investors.
Newsfilter
9.5
03-23Newsfilter
Talphera Reports 2025 Financial Results and Clinical Milestones
  • Clinical Study Progress: Talphera has achieved 50% enrollment in the NEPHRO CRRT clinical study, with all 12 clinical sites now capable of enrolling patients, which is expected to accelerate patient recruitment and enhance study efficiency towards a 2026 completion.
  • Successful Financing: The company successfully closed a $4.1 million financing tranche as a condition for reaching the 35-patient enrollment milestone, thereby strengthening its liquidity to support ongoing R&D efforts.
  • Financial Status: As of December 31, 2025, Talphera reported cash and investments totaling $20.4 million, despite a net loss of $3.8 million in Q4 2025, indicating a continued increase in R&D expenditures.
  • Future Outlook: Cash operating expenses are projected to range between $17 million and $18 million in 2026, up from approximately $13 million in 2025, primarily driven by the NEPHRO CRRT study and related costs, reflecting the company's focus on future market opportunities.
moomoo
9.5
03-23moomoo
TALPHERA, INC Reports Q4 Net Loss from Continuing Operations of USD 3.772 Million
  • Company Overview: Talpher, Inc. has reported its net income for the fourth quarter.

  • Financial Performance: The net income from continuing operations stands at $3.772 million.

Wall Street analysts forecast TLPH stock price to rise
2 Analyst Rating
Wall Street analysts forecast TLPH stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
3.00
Averages
3.25
High
3.50
Current: 0.000
sliders
Low
3.00
Averages
3.25
High
3.50
HC Wainwright & Co.
Ed Arce
Strong Buy
Reiterates
$6
AI Analysis
2025-04-01
Reason
HC Wainwright & Co.
Ed Arce
Price Target
$6
AI Analysis
2025-04-01
Reiterates
Strong Buy
Reason

Valuation Metrics

The current forward P/E ratio for Talphera Inc (TLPH.O) is -4.36, compared to its 5-year average forward P/E of -1.86. For a more detailed relative valuation and DCF analysis to assess Talphera Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.86
Current PE
-4.36
Overvalued PE
0.62
Undervalued PE
-4.35

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.72
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
1.28
Undervalued EV/EBITDA
-2.71

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
510.81
Current PS
7835.82
Overvalued PS
2373.98
Undervalued PS
-1352.37

Financials

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Frequently Asked Questions

What is Talphera Inc (TLPH) stock price today?

The current price of TLPH is 0.7458 USD — it has increased 0.54

What is Talphera Inc (TLPH)'s business?

Talphera, Inc. is a specialty pharmaceutical company focused on the development and commercialization of therapies for use in medically supervised settings. The Company’s portfolio consists of nafamostat product candidates and pre-filled syringe product candidates. The Company’s lead product candidate, Niyad, is a lyophilized formulation of nafamostat and is being studied under an investigational device exemption (IDE) as an anticoagulant for the extracorporeal circuit. Niyad is used in adult patients undergoing continuous renal replacement therapy (CRRT). LTX-608 is its nafamostat formulation for direct IV infusion being explored as an investigational product for one or more indications, including antiviral treatment, or treatment of acute respiratory distress syndrome (ARDS) disseminated intravascular coagulation (DIC), or acute pancreatitis. The Company’s two ready-to-use pre-filled syringe (PFS) product candidates include Fedsyra and phenylephrine.

What is the price predicton of TLPH Stock?

Wall Street analysts forecast TLPH stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for TLPH is3.25 USD with a low forecast of 3.00 USD and a high forecast of 3.50 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Talphera Inc (TLPH)'s revenue for the last quarter?

Talphera Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Talphera Inc (TLPH)'s earnings per share (EPS) for the last quarter?

Talphera Inc. EPS for the last quarter amounts to -0.06 USD, decreased -14.29

How many employees does Talphera Inc (TLPH). have?

Talphera Inc (TLPH) has 12 emplpoyees as of March 31 2026.

What is Talphera Inc (TLPH) market cap?

Today TLPH has the market capitalization of 37.33M USD.