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STTK Should I Buy

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Intellectia

Should You Buy Shattuck Labs Inc (STTK) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
5.960
1 Day change
-1.00%
52 Week Range
6.250
Analysis Updated At
2026/03/06
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Shattuck Labs Inc (STTK) is not a strong buy for a beginner investor with a long-term strategy at this time. Despite positive developments in reducing losses and promising Phase 1 clinical trials for SL-325, the stock's overbought technical indicators, lack of strong proprietary trading signals, and potential short-term downside risks suggest holding off on immediate investment.

Technical Analysis

The stock is currently in an overbought condition with an RSI of 91.329, indicating potential for a pullback. MACD is positive and expanding, suggesting bullish momentum. Moving averages are bullish (SMA_5 > SMA_20 > SMA_200). Current price is above R1 (5.587) and approaching R2 (6.104), signaling limited upside in the short term.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
6
Buy
9

Positive Catalysts

  • Analysts have upgraded the stock to 'Buy' and 'Overweight' ratings with price targets of $14 and $15, citing the potential of SL-

  • Financial losses have significantly narrowed, reflecting improved cost management.

  • Sufficient cash runway into 2029, reducing liquidity concerns.

  • Phase 1 trial for SL-325 is progressing well, with final cohort completion expected by Q2 2026.

Neutral/Negative Catalysts

  • The stock is overbought based on RSI, increasing the likelihood of a short-term pullback.

  • Historical financial performance shows declining revenue and net income YoY.

  • Stock trend analysis suggests a 60% chance of a -7.33% decline in the next week.

  • No significant hedge fund or insider trading activity to indicate strong institutional confidence.

Financial Performance

For Q4 2025, net loss improved to $12.6M from $18.7M YoY, and full-year 2025 net loss narrowed to $48.8M from $75.4M in 2024. Cash reserves increased to $78.1M, providing a runway into 2029. However, revenue dropped significantly in Q3 2025 (-66.63% YoY), and EPS declined by 57.58% YoY.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Recent analyst ratings are bullish, with Needham and Piper Sandler assigning 'Buy' and 'Overweight' ratings, respectively, and price targets of $14 and $15. Analysts are optimistic about SL-325's potential efficacy and safety profile in treating inflammatory bowel disease.

Wall Street analysts forecast STTK stock price to rise
3 Analyst Rating
Wall Street analysts forecast STTK stock price to rise
2 Buy
1 Hold
0 Sell
Moderate Buy
Current: 6.020
sliders
Low
4
Averages
8.33
High
15
Current: 6.020
sliders
Low
4
Averages
8.33
High
15
Wedbush
Outperform
maintain
$4 -> $8
AI Analysis
2026-03-06
New
Reason
Wedbush
Price Target
$4 -> $8
AI Analysis
2026-03-06
New
maintain
Outperform
Reason
Wedbush raised the firm's price target on Shattuck Labs to $8 from $4 and keeps an Outperform rating on the shares. The firm notes the company reported earnings, confirmed Crohn's disease as its lead indication, and reiterated guidance for SL-325 results in Q2 2026. Wedbush looks for low ADA rates in the healthy volunteer data as initial proof of differentiation from TL1A directed competitors in addition to other markers like receptor occupancy as mechanistic evidence supporting development.
Needham
Joseph Stringer
Hold
to
Buy
initiated
$14
2026-03-06
New
Reason
Needham
Joseph Stringer
Price Target
$14
2026-03-06
New
initiated
Hold
to
Buy
Reason
Needham analyst Joseph Stringer put a Buy rating and $14 price target on Shattuck Labs following a transfer of coverage. The firm previously had a Hold rating on the shares. The analyst is bullish on Shattuck's lead asset SL-325, an anti-DR3 antibody in Phase 1 development for inflammatory bowel disease. The company's DR3-targeting approach is "highly differentiated, "and SL-325 has the potential for a better efficacy profile compared to anti-TL1A antibodies, the analyst tells investors in a research note. Needham sees a "highly favorable" risk/reward at current share levels.
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