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SLXN Overview

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ET
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Intellectia

Loading chart...

High
5.450
Open
4.290
VWAP
4.81
Vol
313.47K
Mkt Cap
2.06M
Low
4.064
Amount
1.51M
EV/EBITDA(TTM)
--
Total Shares
419.00K
EV
1.20M
EV/OCF(TTM)
--
P/S(TTM)
--
Silexion Therapeutics Corp is an Israel-based oncology-focused biotechnology company. The Company is engaged in development of treatments for unsatisfactorily treated solid tumor cancers, which have the mutated KRAS oncogene. The KRAS gene is an oncogene that is involved in regulation of cell division as a result of its ability to relay external signals to the cell nucleus. Based on its research of refractory solid tumor cancers, it is developing a platform focused on the silencing of the KRAS oncogene using ribonucleic acid (RNA)-interference therapeutics. Its lead product candidate, SIL-204B, consists of locally administered small interfering RNAs (siRNA), in an extended-release formulation, as a preferred treatment of locally advanced pancreatic cancer patients, in combination with standard-of-care chemotherapy. Its clinical-stage pipeline is focused on treatment for pancreatic cancer (PC) tumors bearing the KRAS G12D or KRAS G12V mutations where metastases have not been detected.
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Events Timeline

(ET)
2026-05-13
08:20:00
Silexion Therapeutics Initiates GMP Clinical Batch Manufacturing of SIL204
select
2026-04-28 (ET)
2026-04-28
09:30:00
Silexion Therapeutics Submits CTA for SIL204 Clinical Trial
select
2026-03-24 (ET)
2026-03-24
09:50:00
Silexion Receives Israeli Approval to Initiate SIL204 Clinical Trial
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2026-01-06 (ET)
2026-01-06
07:40:00
Silexion Therapeutics to Initiate SIL204 Clinical Trials in 2025
select
2025-12-16 (ET)
2025-12-16
08:50:00
Silexion Therapeutics Initiates SIL204 Clinical Trial Application in Israel
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2025-12-02 (ET)
2025-12-02
08:10:00
Silexion Receives Regulatory Guidance for Phase 2/3 Trial of SIL204
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News

seekingalpha
8.5
05-26seekingalpha
Silexion Therapeutics Announces 1-for-10 Reverse Stock Split
  • Reverse Stock Split Announcement: Silexion Therapeutics has announced a 1-for-10 reverse stock split effective at market close on May 28, 2026, aimed at increasing the share price to comply with Nasdaq's minimum bid price requirement, thereby mitigating delisting risks.
  • Par Value Adjustment: Following the reverse split, the par value of ordinary shares will increase from $0.0135 to $0.135 per share, reflecting the company's commitment to shareholder value and compliance in the capital markets.
  • Stock Price Reaction: Following the announcement of the reverse split, Silexion Therapeutics' stock price fell by 6.14% to $0.47, indicating that market reactions to this decision may impact investor confidence and future fundraising capabilities.
  • Funding Strategy: The company also plans to issue new warrants at $0.50 per share to raise $1 million, a move that will provide necessary liquidity to support its research and operational needs.
Newsfilter
8.5
05-26Newsfilter
Silexion Announces 1-for-10 Reverse Stock Split
  • Reverse Split Implementation: Silexion Therapeutics announced a 1-for-10 reverse stock split effective after market close on May 28, 2026, aimed at increasing the per-share trading price to comply with Nasdaq's minimum bid price requirement, thereby enhancing the company's position in the capital markets.
  • Shareholder Impact: Following the reverse split, the par value of ordinary shares will rise from $0.0135 to $0.135, with shareholders not needing to take any action as their share counts will be automatically adjusted, ensuring liquidity and market stability.
  • Clinical Trial Preparation: Silexion plans to initiate its Phase 2/3 trial of SIL204 this quarter, and the reverse split will provide a stronger foundation for market performance to attract more investors and support its clinical execution.
  • Strategic Growth Support: This reverse split is not only to meet Nasdaq compliance but also enhances the company's flexibility for equity financing, aiding Silexion's innovative development in the treatment of KRAS-driven cancers.
NASDAQ.COM
2.0
05-21NASDAQ.COM
HCW Biologics Stock Surges 129% Amid Concerns
  • HCW Biologics Surge: HCW Biologics Inc. (HCWB) saw its stock price soar over 129% to $2.43 on Wednesday, despite concerns about potential cash shortages, with only $1.22 million on hand as of March 31, 2026, which could hinder future R&D efforts.
  • Silexion Clinical Progress: Silexion Therapeutics Corp. (SLXN) received approval from the Israeli Ministry of Health to initiate its Phase 2/3 trial for SIL204 in locally advanced pancreatic cancer, with shares rising 96.95% to $0.53, reflecting market confidence in its development prospects.
  • Immunovant Positive Data: Immunovant Inc. (IMVT) reported encouraging results from its Phase 2b trial of MVT-1402, with 72.7% of patients showing over 20% symptom improvement after 16 weeks, leading to a 35.26% stock increase to $35.56, indicating strong potential in autoimmune disease treatment.
  • Modular Medical Commercialization: Modular Medical Inc. (MODD) received FDA clearance for its next-generation tubeless insulin patch pump, with initial shipments expected by the end of Q2 2026, resulting in an 18.62% stock rise to $3.95, marking a significant step towards commercialization.
seekingalpha
9.5
05-18seekingalpha
Silexion Therapeutics Q1 Earnings Beat Expectations
  • Earnings Surprise: Silexion Therapeutics reported a Q1 GAAP EPS of -$0.85, beating expectations by $0.44, indicating an improvement in financial performance despite still being in the red.
  • Cash Flow Status: As of March 31, 2026, the company's cash and cash equivalents stood at $2.4 million, down from $6.0 million as of December 31, 2025, primarily due to ongoing operating expenses supporting clinical trial preparations, reflecting continued investment in R&D.
  • Clinical Trial Readiness: The cash decrease is mainly attributed to preparations for the Phase 2/3 clinical trial of SIL204, demonstrating the company's commitment to advancing critical R&D projects despite facing funding pressures.
  • Financing Initiative: Silexion Therapeutics has priced new warrants at $0.50 each to raise $1 million, aiming to bolster liquidity to support its clinical trials and operational needs.
Newsfilter
9.0
05-18Newsfilter
Israeli Ministry Approves Silexion's Clinical Trial for SIL204
  • Clinical Trial Approval: On March 24, 2026, the Israeli Ministry of Health approved Silexion's Phase 2/3 clinical trial for SIL204, marking a significant regulatory milestone that enhances the company's competitive position in KRAS-driven cancer treatment.
  • Application Submitted in Germany: On April 28, 2026, Silexion submitted a Clinical Trial Application to Germany via the EU Clinical Trials Information System, indicating the company's strategic expansion into the European market, which is expected to accelerate the clinical development of SIL204.
  • Trial Initiation Planned: The Phase 2/3 clinical trial for SIL204 is expected to commence in the second quarter of 2026, initially enrolling approximately 18 patients, followed by an expansion to 166 patients, aiming to evaluate its efficacy in combination with standard chemotherapy, potentially offering new treatment options for patients.
  • Financial Update: As of March 31, 2026, Silexion reported cash and cash equivalents of $2.4 million, a significant decrease from $6 million as of December 31, 2025, reflecting increased operating expenses associated with preparations for the upcoming clinical trial.
seekingalpha
8.5
05-15seekingalpha
Silexion Therapeutics Signs New Financing Agreement
  • Financing Agreement Signed: Silexion Therapeutics announced the signing of an agreement for the immediate exercise of approximately 2 million outstanding warrants at a reduced price of $0.50 per share, expected to raise around $1 million in gross proceeds, enhancing liquidity to support operations.
  • New Warrants Issued: As part of the deal, the company will issue approximately 2.05 million Series C warrants and 1.95 million Series D warrants, both priced at $0.50 per share, with Series C warrants expiring in 5 years and Series D in 24 months, providing flexible financing options.
  • Shareholder Approval Required: The new warrants will require shareholder approval before they can be exercised, which may affect the timeliness of the transaction and the company's future financing strategy, ensuring shareholder interests are safeguarded.
  • Clear Use of Funds: The net proceeds from this financing will primarily be used for working capital and other general corporate purposes, reflecting the company's cautious approach to capital management aimed at supporting its long-term growth strategy.
Wall Street analysts forecast SLXN stock price to rise
2 Analyst Rating
Wall Street analysts forecast SLXN stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
6.00
Averages
9.00
High
12.00
Current: 0.000
sliders
Low
6.00
Averages
9.00
High
12.00
Litchfield Hills
Theodore O'Neill
Buy
initiated
$6
AI Analysis
2025-12-15
Reason
Litchfield Hills
Theodore O'Neill
Price Target
$6
AI Analysis
2025-12-15
initiated
Buy
Reason
Litchfield Hills analyst Theodore O'Neill initiated coverage of Silexion Therapeutics with a Buy rating and $6 price target. Silexion Therapeutics is targeting unmet need in KRAS-driven cancers and its siRNA platform takes a fundamentally different approach from current KRAS-targeted therapies, the analyst tells investors. The company is positioned to enter late-stage clinical development, with regulatory submission to the Israel Ministry of Health in Q4 followed by filings in Germany and the broader European Union in Q1, the analyst noted.

Valuation Metrics

The current forward P/E ratio for Silexion Therapeutics Corp (SLXN.O) is 0.00, compared to its 5-year average forward P/E of -0.16. For a more detailed relative valuation and DCF analysis to assess Silexion Therapeutics Corp's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-0.16
Current PE
0.00
Overvalued PE
0.16
Undervalued PE
-0.47

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

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Frequently Asked Questions

What is Silexion Therapeutics Corp (SLXN) stock price today?

The current price of SLXN is 4.9095 USD — it has increased 14.83

What is Silexion Therapeutics Corp (SLXN)'s business?

Silexion Therapeutics Corp is an Israel-based oncology-focused biotechnology company. The Company is engaged in development of treatments for unsatisfactorily treated solid tumor cancers, which have the mutated KRAS oncogene. The KRAS gene is an oncogene that is involved in regulation of cell division as a result of its ability to relay external signals to the cell nucleus. Based on its research of refractory solid tumor cancers, it is developing a platform focused on the silencing of the KRAS oncogene using ribonucleic acid (RNA)-interference therapeutics. Its lead product candidate, SIL-204B, consists of locally administered small interfering RNAs (siRNA), in an extended-release formulation, as a preferred treatment of locally advanced pancreatic cancer patients, in combination with standard-of-care chemotherapy. Its clinical-stage pipeline is focused on treatment for pancreatic cancer (PC) tumors bearing the KRAS G12D or KRAS G12V mutations where metastases have not been detected.

What is the price predicton of SLXN Stock?

Wall Street analysts forecast SLXN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SLXN is9.00 USD with a low forecast of 6.00 USD and a high forecast of 12.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Silexion Therapeutics Corp (SLXN)'s revenue for the last quarter?

Silexion Therapeutics Corp revenue for the last quarter amounts to -2.75M USD, increased 66.61

What is Silexion Therapeutics Corp (SLXN)'s earnings per share (EPS) for the last quarter?

Silexion Therapeutics Corp. EPS for the last quarter amounts to -3646000.00 USD, increased 48.27

How many employees does Silexion Therapeutics Corp (SLXN). have?

Silexion Therapeutics Corp (SLXN) has 13 emplpoyees as of May 31 2026.

What is Silexion Therapeutics Corp (SLXN) market cap?

Today SLXN has the market capitalization of 2.06M USD.