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SLNO Should I Buy

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Intellectia

Should You Buy Soleno Therapeutics Inc (SLNO) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
52.670
1 Day change
-0.21%
52 Week Range
90.320
Analysis Updated At
2026/04/17
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Soleno Therapeutics Inc (SLNO) is not a good buy for a beginner investor with a long-term strategy at this time. The stock is trading near its acquisition price of $53, leaving limited upside potential. Additionally, the ongoing lawsuits and weak financial performance further diminish its attractiveness.

Technical Analysis

The stock is overbought with an RSI of 90.52, and the MACD is positively contracting. The current price of $52.57 is near the resistance level of $53.013, indicating limited room for further price appreciation. The stock has a 60% chance of declining slightly in the next day and week.

Options Data

Bearish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
6
Buy
7

Positive Catalysts

  • The acquisition deal by Neurocrine Biosciences at $53 per share provides a floor for the stock price, reducing downside risk.

Neutral/Negative Catalysts

  • Multiple class action lawsuits related to safety concerns in clinical trials and product disclosures. Downgrades by analysts with price targets aligned to the acquisition price, indicating limited growth potential. Weak financial performance with significant YoY declines in net income and EPS.

Financial Performance

In Q4 2025, revenue remained flat YoY at $91.73M. However, net income dropped significantly by -176.71% YoY, and EPS fell by -156.69% YoY, indicating poor profitability. Gross margin remained high at 99.06%, but this did not translate into improved earnings.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

All recent analyst ratings have downgraded SLNO to Neutral or Hold, with price targets reduced to $53, citing the acquisition deal. Analysts do not expect a superior bid or significant upside from the current price.

Wall Street analysts forecast SLNO stock price to rise
8 Analyst Rating
Wall Street analysts forecast SLNO stock price to rise
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 52.780
sliders
Low
75
Averages
110.5
High
125
Current: 52.780
sliders
Low
75
Averages
110.5
High
125
Wells Fargo
Overweight
to
Equal Weight
downgrade
$110 -> $53
AI Analysis
2026-04-17
New
Reason
Wells Fargo
Price Target
$110 -> $53
AI Analysis
2026-04-17
New
downgrade
Overweight
to
Equal Weight
Reason
Wells Fargo downgraded Soleno Therapeutics (SLNO) to Equal Weight from Overweight with a price target of $53, down from $110. The firm cites Neurocrine's (NBIX) pending acquisition of the company at $53 per share for the downgrade. The deal is expected to close in Q3, the analyst tells investors in a research note.
Wells Fargo
Overweight
to
Equal Weight
downgrade
$110 -> $53
2026-04-17
New
Reason
Wells Fargo
Price Target
$110 -> $53
2026-04-17
New
downgrade
Overweight
to
Equal Weight
Reason
Wells Fargo downgraded Soleno Therapeutics to Equal Weight from Overweight with a price target of $53, down from $110.
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