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SLNO Should I Buy

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Intellectia

Should You Buy Soleno Therapeutics Inc (SLNO) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
52.950
1 Day change
52 Week Range
90.320
Analysis Updated At
2026/04/24
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Soleno Therapeutics (SLNO) is not a good buy for a long-term beginner investor at this time. The stock is trading near its acquisition price of $53, leaving minimal upside potential. Additionally, the company is facing multiple securities class action lawsuits, and its financial performance has significantly deteriorated in the latest quarter. Analysts have downgraded the stock due to the pending acquisition, and there are no strong proprietary trading signals to suggest a compelling entry point.

Technical Analysis

The stock is in an overbought condition with an RSI of 89.095. The MACD histogram is positive at 0.218, but it is contracting, indicating weakening momentum. The price is trading near resistance levels (R1: 52.795, R2: 52.878) with minimal room for further upside. Moving averages are converging, signaling a lack of clear trend direction.

Options Data

Neutral
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
8
Buy
6

Positive Catalysts

  • The pending acquisition by Neurocrine Biosciences at $53 per share provides a floor to the stock price, reducing downside risk.

Neutral/Negative Catalysts

  • The company is facing multiple securities class action lawsuits related to undisclosed safety risks of its product DCCR. Analysts have downgraded the stock across the board due to the acquisition, and there is no expectation of a higher bid. Financial performance has deteriorated significantly, with net income and EPS showing steep declines.

Financial Performance

In Q4 2025, revenue remained flat YoY at $91.73M. However, net income dropped by -176.71% YoY to $42.94M, and EPS fell by -156.69% YoY to 0.72. Gross margin remained strong at 99.06%, but overall financial performance indicates significant challenges.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts have downgraded the stock to Neutral or Hold ratings with a price target of $53, citing the pending acquisition by Neurocrine Biosciences. There is no expectation of a superior bid, and the stock is unlikely to outperform.

Wall Street analysts forecast SLNO stock price to rise
8 Analyst Rating
Wall Street analysts forecast SLNO stock price to rise
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 52.950
sliders
Low
75
Averages
110.5
High
125
Current: 52.950
sliders
Low
75
Averages
110.5
High
125
Wells Fargo
Overweight
to
Equal Weight
downgrade
$110 -> $53
AI Analysis
2026-04-17
Reason
Wells Fargo
Price Target
$110 -> $53
AI Analysis
2026-04-17
downgrade
Overweight
to
Equal Weight
Reason
Wells Fargo downgraded Soleno Therapeutics (SLNO) to Equal Weight from Overweight with a price target of $53, down from $110. The firm cites Neurocrine's (NBIX) pending acquisition of the company at $53 per share for the downgrade. The deal is expected to close in Q3, the analyst tells investors in a research note.
Wells Fargo
Overweight
to
Equal Weight
downgrade
$110 -> $53
2026-04-17
Reason
Wells Fargo
Price Target
$110 -> $53
2026-04-17
downgrade
Overweight
to
Equal Weight
Reason
Wells Fargo downgraded Soleno Therapeutics to Equal Weight from Overweight with a price target of $53, down from $110.
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