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SGMO.O Overview

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Intellectia

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High
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Open
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VWAP
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Vol
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Mkt Cap
82.71M
Low
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Amount
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EV/EBITDA(TTM)
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Total Shares
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EV
52.63M
EV/OCF(TTM)
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P/S(TTM)
1.26
Sangamo Therapeutics, Inc. is a genomic medicine company. The Company’s zinc finger (ZF) epigenetic regulators are ideally suited to potentially address neurological disorders and its capsid engineering platform has demonstrated the ability to expand delivery beyond available intrathecal delivery capsids, including in the central nervous system (CNS), in preclinical studies. Zinc finger technologies are derived from naturally occurring human proteins. They are composed of a DNA-binding domain, which binds with precision to any sequence of DNA, and various functional domains (such as nucleases and transcription factors) based on therapeutic needs. Its pipeline includes Chronic Neuropathic Pain - ST-503 and Isaralgagene civaparvovec (ST-920). ST-503 is an investigational epigenetic regulator for the treatment of intractable pain due to iSFN, a type of chronic neuropathic pain. ST-920 is a wholly owned gene therapy product candidate for the treatment of Fabry disease.
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Events Timeline

(ET)
2026-03-30
16:10:00
Sangamo Reports Q4 Revenue of $14.23M
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2026-03-30
16:10:00
Company's Financial Guidance Depends on Securing Additional Funding
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2026-03-09 (ET)
2026-03-09
08:10:00
Sangamo Submits ST-920 for Accelerated Approval
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2026-02-03 (ET)
2026-02-03
09:20:00
Sangamo Names Nikunj Jain as Interim CFO
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2026-02-03
09:20:00
Sangamo CFO Prathyusha Duraibabu Departs, Nikunj Jain Appointed Interim CFO
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2026-02-03
09:20:00
Sangamo Therapeutics Prices 35.19M Share Offering at $25M
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2025-12-18 (ET)
2025-12-18
08:20:00
Sangamo Submits BLA for ST-920 Accelerated Approval to FDA
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News

seekingalpha
9.5
05-14seekingalpha
Sangamo Therapeutics Q1 2026 Earnings Call Insights
  • BLA Submission Progress: Sangamo is advancing the rolling submission of the BLA for ST-920 in Fabry disease, with expectations to complete it as early as this summer, contingent on securing adequate funding, which could open significant market access opportunities for the company.
  • Stock Trading Change: Sangamo's common stock has transitioned to trading on the OTCQB market due to noncompliance with NASDAQ's minimum bid requirements, and the company plans to appeal the delisting determination in June, which may impact investor confidence.
  • Funding Needs Focus: Management emphasized actively seeking additional capital and evaluating all strategic options to maximize asset value, highlighting the company's dependency on financing in the current market environment.
  • FDA Regulatory Dynamics: The FDA confirmed that no additional confirmatory study is required for ST-920, allowing for the submission of 104-week data to support traditional approval, providing greater flexibility and confidence in regulatory approval processes for the company.
seekingalpha
9.5
05-13seekingalpha
Sangamo Therapeutics to Announce Q1 Earnings on May 14
  • Earnings Announcement Date: Sangamo Therapeutics (SGMO) is set to release its Q1 2023 earnings on May 14 after market close, with consensus EPS estimated at $0.04 and revenue projected at $33.73 million, reflecting a substantial 427% year-over-year increase.
  • Performance Expectations: Over the past year, SGMO has only beaten EPS and revenue estimates 25% of the time, indicating challenges in profitability and revenue growth that could impact investor confidence moving forward.
  • Estimate Revision Trends: In the last three months, EPS estimates saw no upward revisions and one downward revision, while revenue estimates experienced one upward and one downward revision, suggesting instability in market expectations regarding the company's future performance.
  • Market Response: Despite facing performance pressures, Sangamo is advancing its neurology pipeline and targeting a Fabry BLA submission, demonstrating ongoing commitment to R&D efforts that may lay the groundwork for future growth.
Newsfilter
9.5
05-11Newsfilter
Sangamo Therapeutics Schedules Q1 2026 Financial Results Release
  • Financial Results Announcement: Sangamo Therapeutics is set to release its Q1 2026 financial results after market close on May 14, 2026, reflecting the company's commitment to transparency and investor communication.
  • Conference Call Details: The company will hold a conference call at 4:30 PM Eastern on the same day to discuss financial results and business updates, which is expected to attract significant attention from investors and analysts.
  • Participation Registration Recommended: Participants are advised to register and join the call 10 minutes early, with options for both dial-in and dial-out connections provided to enhance engagement and interactivity during the call.
  • Replay Availability: A replay of the financial results will be accessible on the company's website under the 'Investors and Media' section post-conference, further improving information accessibility and transparency for stakeholders.
stocktwits
9.5
03-31stocktwits
PEPG, SGMO, and PHR Shares Decline Amid Disappointing Results
  • PEPG Trial Disappointment: PepGen's Phase 2 Freedom 2 study results showed no significant improvements in walking speed or hand strength at the starting dose of 5 mg/kg, leading to a 45% plunge in premarket trading, reflecting investor disappointment in the therapy's efficacy.
  • SGMO Earnings Miss: Sangamo Therapeutics reported a Q4 loss per share of $0.11, wider than the expected $0.05 loss, despite revenue rising to $14.23 million, indicating pressure on the company's funding outlook that may impact future operations.
  • PHR Revenue Outlook Cut: Phreesia lowered its fiscal 2027 revenue outlook to $510 million to $520 million, below analyst expectations of $552.1 million, resulting in a 27% drop in share price and prompting downgrades from multiple brokerages.
  • Market Sentiment Fluctuates: While retail sentiment for PEPG, SGMO, and PHR on Stocktwits was 'extremely bullish', the disappointing performance and unclear outlook have severely undermined investor confidence, reflecting a cautious attitude towards biotech stocks.
Yahoo Finance
8.5
03-31Yahoo Finance
Sangamo Therapeutics Secures Over $130 Million in Funding and FDA Fast Track Designation
  • Funding Progress: Since the beginning of 2025, Sangamo Therapeutics has raised over $130 million through non-dilutive license fees, milestone payments, and equity financing, providing essential funding for ongoing research and enhancing its competitive position in the market.
  • Clinical Advancement: The company has initiated a rolling submission of a Biologics License Agreement (BLA) for ST-920 to the FDA, having completed both non-clinical and clinical modules, marking its first wholly-owned BLA submission that could expedite the FDA approval process.
  • Fast Track Designation: Sangamo received Fast Track designation from the FDA for SC503, an investigational treatment for intractable pain due to small fiber neuropathy, highlighting its potential to address significant unmet medical needs in this area.
  • Clinical Trial Activation: Six clinical sites have been activated for the Phase I/II STAN study in chronic neuropathic pain, demonstrating the company's proactive efforts in advancing clinical research to provide new treatment options for patients.
seekingalpha
9.5
03-30seekingalpha
Sangamo Therapeutics Q4 2025 Earnings Call Insights
  • Significant Pipeline Progress: Sangamo made notable advancements in 2025, particularly with positive results from the registrational STAAR study for Fabry disease, where the eGFR slope at 52 weeks was promising, and the FDA confirmed this may serve as the primary basis for accelerated approval, indicating the company's ability to achieve positive outcomes amid regulatory complexities.
  • BLA Submission Progress: The company is advancing its first wholly owned BLA's rolling submission, with expectations to complete it as early as this summer, despite facing challenges related to limited cash resources, which will lay the groundwork for future commercialization efforts.
  • Successful Fundraising: Since the beginning of 2025, Sangamo has raised over $130 million through nondilutive license fees, milestone payments, and equity financing, providing essential financial support for ongoing R&D and market expansion initiatives.
  • Neurology Pipeline Expansion: The company has activated six clinical sites in the STAND study and entered into a third neurology capsid license agreement with Eli Lilly to deliver genomic medicines for up to five CNS disease targets, demonstrating its strategic positioning in the neurology sector.
Wall Street analysts forecast SGMO.O stock price to rise
4 Analyst Rating
Wall Street analysts forecast SGMO.O stock price to rise
1 Buy
3 Hold
0 Sell
Hold
Current: 0.000
sliders
Low
1.00
Averages
3.75
High
10.00
Current: 0.000
sliders
Low
1.00
Averages
3.75
High
10.00
H.C. Wainwright
Patrick Trucchio
Buy
downgrade
$10 -> $5
AI Analysis
2026-05-26
New
Reason
H.C. Wainwright
Patrick Trucchio
Price Target
$10 -> $5
AI Analysis
2026-05-26
New
downgrade
Buy
Reason
H.C. Wainwright analyst Patrick Trucchio lowered the firm's price target on Sangamo to $5 from $10 and keeps a Buy rating on the shares. While stating that its regulatory and clinical thesis for isaralgagene civaparvovec in Fabry disease remains intact, the firm is lowering its price target to reflect the uncertainty of securing a commercialization partner or the funding to continue operations through the final steps of the Fabry rolling biologics license application filing while supporting the advancement of its neurology pipeline.
Barclays
Overweight -> Equal Weight
downgrade
$5 -> $1
2025-11-07
Reason
Barclays
Price Target
$5 -> $1
2025-11-07
downgrade
Overweight -> Equal Weight
Reason
Barclays downgraded Sangamo to Equal Weight from Overweight with a price target of $1, down from $5. The company's Q3 report highlighted the FDA's reaffirmation of an accelerated approval path using eGFR slope as the endpoint and its cash runway has been extended into Q1 of 2026, the analyst tells investors in a research note. Barclays steps to the sidelines pending further clarity on a Fabry deal.
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Valuation Metrics

The current forward P/E ratio for Sangamo Therapeutics Inc (SGMO.O) is 0.39, compared to its 5-year average forward P/E of -3.40. For a more detailed relative valuation and DCF analysis to assess Sangamo Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.40
Current PE
0.39
Overvalued PE
0.92
Undervalued PE
-7.72

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
1.73
Current EV/EBITDA
-0.36
Overvalued EV/EBITDA
27.99
Undervalued EV/EBITDA
-24.54

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.00
Current PS
0.57
Overvalued PS
8.88
Undervalued PS
1.11

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Frequently Asked Questions

What is Sangamo Therapeutics Inc (SGMO.O) stock price today?

The current price of SGMO.O is 0 USD — it has increased 24.21

What is Sangamo Therapeutics Inc (SGMO.O)'s business?

Sangamo Therapeutics, Inc. is a genomic medicine company. The Company’s zinc finger (ZF) epigenetic regulators are ideally suited to potentially address neurological disorders and its capsid engineering platform has demonstrated the ability to expand delivery beyond available intrathecal delivery capsids, including in the central nervous system (CNS), in preclinical studies. Zinc finger technologies are derived from naturally occurring human proteins. They are composed of a DNA-binding domain, which binds with precision to any sequence of DNA, and various functional domains (such as nucleases and transcription factors) based on therapeutic needs. Its pipeline includes Chronic Neuropathic Pain - ST-503 and Isaralgagene civaparvovec (ST-920). ST-503 is an investigational epigenetic regulator for the treatment of intractable pain due to iSFN, a type of chronic neuropathic pain. ST-920 is a wholly owned gene therapy product candidate for the treatment of Fabry disease.

What is the price predicton of SGMO.O Stock?

Wall Street analysts forecast SGMO.O stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SGMO.O is3.75 USD with a low forecast of 1.00 USD and a high forecast of 10.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Sangamo Therapeutics Inc (SGMO.O)'s revenue for the last quarter?

Sangamo Therapeutics Inc revenue for the last quarter amounts to 1.44M USD, decreased -77.60

What is Sangamo Therapeutics Inc (SGMO.O)'s earnings per share (EPS) for the last quarter?

Sangamo Therapeutics Inc. EPS for the last quarter amounts to -0.08 USD, decreased -42.86

How many employees does Sangamo Therapeutics Inc (SGMO.O). have?

Sangamo Therapeutics Inc (SGMO.O) has 142 emplpoyees as of May 30 2026.

What is Sangamo Therapeutics Inc (SGMO.O) market cap?

Today SGMO.O has the market capitalization of 82.71M USD.