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RNAC Overview

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ET
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Intellectia

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High
5.940
Open
5.860
VWAP
5.83
Vol
154.16K
Mkt Cap
155.87M
Low
5.670
Amount
898.72K
EV/EBITDA(TTM)
--
Total Shares
26.51M
EV
29.94M
EV/OCF(TTM)
--
P/S(TTM)
54.57
Cartesian Therapeutics, Inc. is a clinical-stage company pioneering cell therapy for the treatment of autoimmune diseases. It leverages its proprietary technology and manufacturing platform to introduce one or more mRNA molecules into cells to enhance their function. The Company’s lead asset, Descartes-08, is a chimeric antigen receptor T-cell therapy (CAR-T) entering Phase 3 clinical development for patients with generalized myasthenia gravis and Phase 2 development for systemic lupus erythematosus, with a Phase 2 basket trial planned in additional autoimmune indications. The Company’s clinical-stage pipeline also includes Descartes-15, a next-generation, autologous anti-B-cell maturation antigen (BCMA) CAR-T being evaluated in a Phase 1 trial in patients with multiple myeloma. Descartes-08 is an autologous chimeric antigen receptor T-cell therapy product targeting B-cell maturation antigen in clinical development for generalized myasthenia gravis and systemic lupus erythematosus.
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Events Timeline

(ET)
2026-03-09
07:10:00
Cartesian Reports FY25 Revenue of $2.797M, Exceeding Expectations
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2026-02-03 (ET)
2026-02-03
07:20:00
Cartesian Therapeutics Grants 12,050 Stock Options to New Employees
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2026-01-09 (ET)
2026-01-09
08:20:00
Cartesian Therapeutics Updates Descartes-08 Program and Initiates Pediatric Trial
select
2026-01-06 (ET)
2026-01-06
07:20:00
Cartesian Therapeutics Grants 7,350 Stock Options to New Employees
select
2025-11-13 (ET)
2025-11-13
16:55:21
Cartesian Reports Encouraging Initial Results from Phase 2 SLE Trial of Descartes-08
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2025-11-06 (ET)
2025-11-06
07:05:06
Cartesian Therapeutics announces Q3 earnings per share of $1.38, compared to $1.13 in the previous year.
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News

seekingalpha
9.5
03-09seekingalpha
Cartesian Therapeutics Reports Disappointing FY Earnings with Significant Revenue Decline
  • Earnings Miss: Cartesian Therapeutics reported a FY GAAP EPS of -$5.02, missing expectations by $2.67, indicating significant challenges in profitability that could undermine investor confidence.
  • Revenue Decline: The company posted revenue of $2.79 million, a staggering 92.8% year-over-year decrease, although it beat estimates by $0.82 million; this drastic decline reflects a sharp reduction in market demand, potentially leading to future liquidity issues.
  • Strong Cash Position: As of December 31, 2025, Cartesian had $126.9 million in cash, cash equivalents, and restricted cash, which is expected to support planned operations, including the ongoing Phase 3 AURORA trial and the initiation of the Phase 2 TRITON trial, through mid-2027.
  • Trial Progress: Despite disappointing financial results, Cartesian continues to advance its AURORA and TRITON trials, demonstrating ongoing investment in R&D that may lay the groundwork for future product launches and market recovery.
Newsfilter
5.0
02-03Newsfilter
Cartesian Therapeutics Grants Stock Options to New Employees
  • Stock Option Grant: On February 2, 2026, Cartesian Therapeutics granted stock options for a total of 12,050 shares to two new employees at an exercise price of $6.79, reflecting the company's commitment to incentivizing new talent.
  • Option Structure: The options will vest 25% on February 2, 2027, followed by monthly vesting over the next 36 months, fully vesting by February 2, 2030, indicating the company's focus on long-term employee retention.
  • Compliance and Incentive Plan: The stock options were granted under Nasdaq Listing Rule 5635(c)(4) as a material inducement for the employees' entry into the company, aimed at attracting and retaining key talent to enhance competitive positioning.
  • Clinical Development Context: Cartesian Therapeutics is pioneering cell therapy for autoimmune diseases, with its lead asset Descartes-08 in Phase 3 trials for myasthenia gravis, showcasing the company's innovative potential and market prospects in the biotechnology sector.
Globenewswire
9.0
01-09Globenewswire
Cartesian Advances Descartes-08 Clinical Trials for Autoimmune Diseases
  • Clinical Trial Progress: Cartesian's Descartes-08 is on track in the Phase 3 AURORA trial for myasthenia gravis, aiming to enroll approximately 100 participants to assess its impact on MG Activities of Daily Living, which could significantly enhance treatment outcomes and expand market share if successful.
  • FDA Approval for New Indication: The IND application for Descartes-08 in myositis has been accepted by the FDA, with plans to initiate a Phase 2 trial in the first half of 2026, providing a potential opportunity for a single pivotal trial that would further strengthen its competitive position in autoimmune diseases.
  • Pediatric Trial Initiation: The Phase 1/2 pediatric trial of Descartes-08 has been initiated for juvenile dermatomyositis, with the FDA granting Rare Pediatric Disease Designation, indicating the company's strategic focus on the pediatric autoimmune disease market.
  • Funding Support Plan: Current cash resources are expected to support the completion of the ongoing Phase 3 trial for Descartes-08 and the initiation of the Phase 2 myositis trial through mid-2027, ensuring continued investment in R&D and maintaining market competitiveness.
Newsfilter
9.0
01-09Newsfilter
Cartesian Advances Descartes-08 Clinical Trials for Autoimmune Diseases
  • Clinical Trial Progress: Enrollment in the Phase 3 AURORA trial of Descartes-08 for myasthenia gravis is on track, with plans to initiate a Phase 2 trial for myositis in the first half of 2026, showcasing the company's ongoing innovation in autoimmune disease treatment.
  • FDA Approval: The IND application for Descartes-08 targeting myositis has been accepted by the FDA, with a randomized double-blind trial planned for the first half of 2026, potentially paving the way for a single pivotal trial and enhancing market competitiveness.
  • Funding Support: The company expects its current cash resources to support planned operations, including the completion of the Phase 3 trial for Descartes-08, through mid-2027, ensuring continuity and stability in its R&D efforts.
  • Pediatric Trial Launch: The Phase 1/2 trial of Descartes-08 in juvenile dermatomyositis has been initiated, with the FDA granting Rare Pediatric Disease Designation, indicating the company's strategic positioning in treating autoimmune diseases in children.
Benzinga
9.0
01-06Benzinga
Johnson & Johnson Reports Positive Phase 2b Results for Lupus Drug Nipocalimab, Plans Phase 3 Trial
  • Positive Study Results: Johnson & Johnson's JASMINE study involving 228 systemic lupus erythematosus patients met its primary endpoint, demonstrating statistically significant improvement in patient response rates at Week 24 compared to placebo, marking the first positive results for an investigational FcRn blocker in this indication.
  • Safety Profile Consistent: Nipocalimab exhibited a safety and tolerability profile consistent with previous Phase 2 studies, with no new safety signals identified, thereby establishing a solid foundation for further clinical development.
  • Significant Market Potential: With systemic lupus erythematosus affecting an estimated 3 to 5 million people globally, including 450,000 in the U.S., the positive study results could provide a strong competitive advantage for Johnson & Johnson in this market.
  • Clear Next Steps: Following the positive Phase 2 results, Johnson & Johnson plans to initiate a Phase 3 program for Nipocalimab, aiming to further validate its therapeutic potential in systemic lupus erythematosus, which could drive future revenue growth for the company.
Globenewswire
5.0
01-06Globenewswire
Cartesian Therapeutics Grants 7,350 Stock Options to New Employees at $6.76 Exercise Price
  • Employee Incentive Program: On January 2, 2026, Cartesian Therapeutics granted 7,350 stock options to two new employees at an exercise price of $6.76, reflecting the company's commitment to talent acquisition aimed at enhancing team stability and innovation capacity.
  • Option Structure: The options will vest 25% on January 2, 2027, followed by equal monthly installments over 36 months, ensuring full vesting by January 2, 2030, which aligns employee interests with long-term company growth.
  • Compliance and Strategy: This grant complies with Nasdaq Listing Rule 5635(c)(4) as a material inducement for employee entry, demonstrating the company's strategic intent to attract and retain key talent in a competitive market.
  • Clinical Development Context: Cartesian focuses on cell therapy for autoimmune diseases and is advancing its lead asset Descartes-08 in clinical development, with talent incentives expected to enhance R&D efficiency and expedite product market entry.
Wall Street analysts forecast RNAC stock price to rise
8 Analyst Rating
Wall Street analysts forecast RNAC stock price to rise
6 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
16.00
Averages
35.00
High
44.00
Current: 0.000
sliders
Low
16.00
Averages
35.00
High
44.00
Cantor Fitzgerald
Neutral -> Overweight
upgrade
$16
AI Analysis
2026-03-09
Reason
Cantor Fitzgerald
Price Target
$16
AI Analysis
2026-03-09
upgrade
Neutral -> Overweight
Reason
Cantor Fitzgerald upgraded Cartesian Therapeutics to Overweight from Neutral with a $16 price target. Cartesian had no major surprises in its Q4 earnings report, as catalyst timing remains the same for Descartes-08, the analyst tells investors in a research note. Despite the upgrade, Cantor's thesis hasn't changed, but thinks these factors -- the competitive space and the potential for later line usage if priced high -- are already priced in.
Cantor Fitzgerald
Neutral -> Overweight
upgrade
2026-03-09
Reason
Cantor Fitzgerald
Price Target
2026-03-09
upgrade
Neutral -> Overweight
Reason
Cantor Fitzgerald upgraded Cartesian Therapeutics to Overweight from Neutral.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for RNAC
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Valuation Metrics

The current forward P/E ratio for Cartesian Therapeutics Inc (RNAC.O) is -1.99, compared to its 5-year average forward P/E of -5.55. For a more detailed relative valuation and DCF analysis to assess Cartesian Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.55
Current PE
-1.99
Overvalued PE
-0.81
Undervalued PE
-10.29

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.24
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
1.08
Undervalued EV/EBITDA
-3.56

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
167.58
Current PS
369.92
Overvalued PS
365.04
Undervalued PS
-29.87

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Frequently Asked Questions

What is Cartesian Therapeutics Inc (RNAC) stock price today?

The current price of RNAC is 5.88 USD — it has increased 0.51

What is Cartesian Therapeutics Inc (RNAC)'s business?

Cartesian Therapeutics, Inc. is a clinical-stage company pioneering cell therapy for the treatment of autoimmune diseases. It leverages its proprietary technology and manufacturing platform to introduce one or more mRNA molecules into cells to enhance their function. The Company’s lead asset, Descartes-08, is a chimeric antigen receptor T-cell therapy (CAR-T) entering Phase 3 clinical development for patients with generalized myasthenia gravis and Phase 2 development for systemic lupus erythematosus, with a Phase 2 basket trial planned in additional autoimmune indications. The Company’s clinical-stage pipeline also includes Descartes-15, a next-generation, autologous anti-B-cell maturation antigen (BCMA) CAR-T being evaluated in a Phase 1 trial in patients with multiple myeloma. Descartes-08 is an autologous chimeric antigen receptor T-cell therapy product targeting B-cell maturation antigen in clinical development for generalized myasthenia gravis and systemic lupus erythematosus.

What is the price predicton of RNAC Stock?

Wall Street analysts forecast RNAC stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for RNAC is35.00 USD with a low forecast of 16.00 USD and a high forecast of 44.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Cartesian Therapeutics Inc (RNAC)'s revenue for the last quarter?

Cartesian Therapeutics Inc revenue for the last quarter amounts to 947.00K USD, increased 1129.87

What is Cartesian Therapeutics Inc (RNAC)'s earnings per share (EPS) for the last quarter?

Cartesian Therapeutics Inc. EPS for the last quarter amounts to -3.56 USD, increased 790.00

How many employees does Cartesian Therapeutics Inc (RNAC). have?

Cartesian Therapeutics Inc (RNAC) has 75 emplpoyees as of March 31 2026.

What is Cartesian Therapeutics Inc (RNAC) market cap?

Today RNAC has the market capitalization of 155.87M USD.