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RLMD Overview

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0.000(0.000%)Aft-market
ET
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0.000
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ET
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Intellectia

Loading chart...

High
6.210
Open
5.900
VWAP
6.00
Vol
1.51M
Mkt Cap
639.83M
Low
5.680
Amount
9.08M
EV/EBITDA(TTM)
--
Total Shares
104.89M
EV
546.82M
EV/OCF(TTM)
--
P/S(TTM)
--
Relmada Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing therapies for central nervous system (CNS) and metabolic disorders. The Company is focused on the development of esmethadone (d-methadone, dextromethadone, REL-1017), an N-methyl-D-aspartate (NMDA) receptor antagonist. Esmethadone, an isomer of methadone, is a new chemical entity (NCE) that potentially addresses areas of high unmet medical need in the treatment of CNS diseases and other disorders. The Company’s lead program, REL-1017, is a NCE and novel NMDA receptor (NMDAR) channel blocker that preferentially targets hyperactive channels while maintaining physiological glutamatergic neurotransmission. Its lead product candidate, esmethadone, is being developed as a rapidly acting, oral agent for the treatment of depression and other potential indications. Sepranolone is its phase IIb ready neurosteroid developed for the potential treatment of Tourette syndrome and other compulsive disorders.
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Events Timeline

(ET)
2026-03-09
16:20:00
Major Averages Volatile Amid Oil Price Spike
select
2026-03-09
12:10:00
Dow Jones Drops Over 400 Points Amid Oil Price Surge
select
2026-03-09
07:30:00
Relmada Therapeutics Signs $160M PIPE Financing Agreement
select
2026-03-09
07:20:00
Relmada Reports 12-Month Interim Data for NDV-01 with 76% Complete Response Rate
select
2026-01-12 (ET)
2026-01-12
07:20:00
Relmada Therapeutics Receives FDA Feedback on NDV-01
select

News

seekingalpha
4.0
03-24seekingalpha
Relmada Therapeutics Stock Rises After Piper Sandler Coverage Launch
  • Analyst Coverage Initiation: Piper Sandler initiated coverage on Relmada Therapeutics (RLMD) with an Overweight rating, arguing that the stock has yet to reflect the full potential of its lead cancer candidate NDV-01, resulting in a price increase on Tuesday.
  • Drug Development Progress: NDV-01, currently in mid-stage development for non-muscle invasive bladder cancer, combines chemotherapy agents gemcitabine and docetaxel, expected to provide significant therapeutic advantages in the market.
  • Market Potential Assessment: Analyst Kelsey Goodwin noted that despite the current stock price not reflecting NDV-01's value in the large NMIBC market, the drug's gradual release design and high translatability of existing evidence lay a solid foundation for future success.
  • Target Price Setting: The analyst set a $12 per share target for RLMD, assuming 20% and 15% peak market shares for NDV-01 in BCG-unresponsive high-risk and intermediate-risk NMIBC, with probabilities of success at 35% and 25%, respectively.
NASDAQ.COM
9.5
03-20NASDAQ.COM
Relmada Reports 2025 Financials and Clinical Advancements
  • Promising Clinical Data: Relmada's bladder cancer candidate NDV-01 demonstrated a 95% complete response rate in the latest 12-month Phase 2 data, with an 80% rate in BCG-unresponsive patients, indicating its potential in treating non-muscle invasive bladder cancer and likely broad adoption in community urology practices.
  • FDA Registration Pathways Confirmed: The company confirmed two Phase 3 registrational pathways for NDV-01 with the FDA, targeting intermediate-risk NMIBC and second-line BCG-unresponsive patients, with studies expected to start in mid-2026 and initial data anticipated by year-end 2026, marking significant clinical development progress.
  • Improved Financials: In Q4 2025, Relmada reported a net loss of $19.9 million, or $0.27 per share, reflecting a decrease in losses, although cash used in operating activities reached $14.6 million, indicating ongoing pressure from R&D investments.
  • Funding Secured Through 2029: With the completion of a $160 million PIPE financing, Relmada expects to be funded through 2029, supporting the Phase 3 program for NDV-01 and other R&D initiatives, enhancing market confidence in its long-term growth prospects.
Yahoo Finance
9.5
03-20Yahoo Finance
Relmada Therapeutics Financial Report Analysis
  • Financial Overview: As of December 31, 2025, Relmada Therapeutics reported a cash balance of $93 million, and despite net proceeds of approximately $94 million from a stock offering, the company faced a net loss of $19.9 million, indicating increasing financial pressure.
  • R&D Expense Trends: Research and development expenses for Q4 2025 were $8.1 million, down from $11 million in Q4 2024, suggesting potential challenges in maintaining R&D momentum after completing two Phase 3 trials.
  • Rising Administrative Costs: General and administrative expenses rose to $12.3 million in Q4 2025 from $8.1 million in Q4 2024, an increase of $4.2 million primarily due to higher compensation costs, which may impact overall profitability.
  • Future Growth Potential: Relmada plans to initiate a Phase 3 rescue program for bladder cancer and a Phase 2 proof of concept trial for Prader-Willi syndrome, indicating a robust pipeline and significant future growth potential in oncology.
NASDAQ.COM
2.0
03-20NASDAQ.COM
Relmada (RLMD) Q4 2025 Earnings Call Transcript
Yahoo Finance
9.5
03-19Yahoo Finance
Relmada Therapeutics Q4 Earnings Call Highlights
  • NDV-01 Clinical Data: NDV-01 demonstrated a 76% complete response rate at 12 months in its Phase 2 trial for non-muscle invasive bladder cancer, with an 80% response rate in BCG-unresponsive patients, indicating strong efficacy in high-risk populations and potential for future market adoption.
  • Registration Trial Plans: Relmada plans to initiate the RESCUE program in mid-2026 across approximately 80 North American sites, with initial data expected by the end of 2026, which will provide critical insights for the company's future in bladder cancer treatment.
  • Financial Position Update: As of the end of 2025, Relmada reported approximately $93 million in cash, along with net proceeds from recent financings totaling around $160 million, which are expected to fund operations through 2029, demonstrating robust financial management.
  • R&D Expense Changes: The company reported R&D expenses of $8.1 million for Q4 2025, down from $11 million in Q4 2024, primarily due to the completion of two Phase 3 trials, reflecting an optimization in resource allocation for research and development activities.
seekingalpha
9.5
03-19seekingalpha
Relmada Therapeutics Q4 Earnings Report Analysis
  • Disappointing Earnings: Relmada Therapeutics reported a Q4 GAAP EPS of -$0.27, missing expectations by $0.13, indicating challenges in profitability that could undermine investor confidence.
  • Decline in R&D Spending: Research and development expenses for the three months ended December 31, 2025, totaled $8.1 million, down $2.9 million from $11.0 million in the same period of 2024, reflecting a contraction in investment that may hinder future product development.
  • Increase in Administrative Costs: General and administrative expenses rose to $12.3 million in Q4 2025, compared to $8.1 million in Q4 2024, an increase of approximately $4.2 million, indicating cost pressures in operational management that could impact overall profitability.
  • Market Reaction Outlook: Given the earnings miss, investors may adopt a cautious stance towards Relmada's future performance, potentially affecting its stock price trajectory and fundraising capabilities.
Wall Street analysts forecast RLMD stock price to rise
2 Analyst Rating
Wall Street analysts forecast RLMD stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
9.00
Averages
9.50
High
10.00
Current: 0.000
sliders
Low
9.00
Averages
9.50
High
10.00
Piper Sandler
Overweight
initiated
$12
AI Analysis
2026-03-24
New
Reason
Piper Sandler
Price Target
$12
AI Analysis
2026-03-24
New
initiated
Overweight
Reason
Piper Sandler initiated coverage of Relmada Therapeutics with an Overweight rating and $12 price target. The firm says the company is advancing NDV-01, a novel intravesicle treatment for non-muscle invasive bladder cancer with "several key advantages" versus existing options. These include the benefits of chemo combination therapy and sustained-release formulation for increased exposure, the analyst tells investors in a research note.
Mizuho
Uy Ear
Outperform
maintain
$10 -> $19
2026-03-20
New
Reason
Mizuho
Uy Ear
Price Target
$10 -> $19
2026-03-20
New
maintain
Outperform
Reason
Mizuho analyst Uy Ear raised the firm's price target on Relmada Therapeutics to $19 from $10 and keeps an Outperform rating on the shares. The company reported "productive" Q4 results, marked by continued execution, the analyst tells investors in a research note. The firm says the better than expected 12-months durability data strengthens its conviction in NDV-01's "best-in-class potential" and market opportunity.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for RLMD
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Valuation Metrics

The current forward P/E ratio for Relmada Therapeutics Inc (RLMD.O) is -5.60, compared to its 5-year average forward P/E of -2.26. For a more detailed relative valuation and DCF analysis to assess Relmada Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.26
Current PE
-5.60
Overvalued PE
-0.19
Undervalued PE
-4.34

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.11
Current EV/EBITDA
-6.45
Overvalued EV/EBITDA
0.85
Undervalued EV/EBITDA
-3.08

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.01
Current PS
0.00
Overvalued PS
0.04
Undervalued PS
-0.02

Financials

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Quarterly

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Frequently Asked Questions

What is Relmada Therapeutics Inc (RLMD) stock price today?

The current price of RLMD is 6.1 USD — it has increased 4.1

What is Relmada Therapeutics Inc (RLMD)'s business?

Relmada Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing therapies for central nervous system (CNS) and metabolic disorders. The Company is focused on the development of esmethadone (d-methadone, dextromethadone, REL-1017), an N-methyl-D-aspartate (NMDA) receptor antagonist. Esmethadone, an isomer of methadone, is a new chemical entity (NCE) that potentially addresses areas of high unmet medical need in the treatment of CNS diseases and other disorders. The Company’s lead program, REL-1017, is a NCE and novel NMDA receptor (NMDAR) channel blocker that preferentially targets hyperactive channels while maintaining physiological glutamatergic neurotransmission. Its lead product candidate, esmethadone, is being developed as a rapidly acting, oral agent for the treatment of depression and other potential indications. Sepranolone is its phase IIb ready neurosteroid developed for the potential treatment of Tourette syndrome and other compulsive disorders.

What is the price predicton of RLMD Stock?

Wall Street analysts forecast RLMD stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for RLMD is9.50 USD with a low forecast of 9.00 USD and a high forecast of 10.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Relmada Therapeutics Inc (RLMD)'s revenue for the last quarter?

Relmada Therapeutics Inc revenue for the last quarter amounts to -20.33M USD, increased 6.59

What is Relmada Therapeutics Inc (RLMD)'s earnings per share (EPS) for the last quarter?

Relmada Therapeutics Inc. EPS for the last quarter amounts to -14596223.00 USD, increased 65.87

How many employees does Relmada Therapeutics Inc (RLMD). have?

Relmada Therapeutics Inc (RLMD) has 17 emplpoyees as of March 25 2026.

What is Relmada Therapeutics Inc (RLMD) market cap?

Today RLMD has the market capitalization of 639.83M USD.