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PVLA Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
142.250
Open
142.250
VWAP
139.71
Vol
6.17K
Mkt Cap
1.91B
Low
138.120
Amount
862.31K
EV/EBITDA(TTM)
--
Total Shares
13.44M
EV
1.76B
EV/OCF(TTM)
--
P/S(TTM)
--
Palvella Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing therapies to treat patients suffering from serious, rare genetic skin diseases for which there are no FDA-approved therapies. The Company is developing a pipeline of product candidates based on its patented QTORIN platform, with an initial focus on serious, rare genetic skin diseases, many of which are lifelong in nature. Its QTORIN product candidates are developed to accommodate the cargo at high concentrations in order to drive sufficient drug to its target deep in the epidermis and dermis. The Company's lead product candidate, QTORIN 3.9% rapamycin anhydrous gel (QTORIN rapamycin), is being evaluated in the Phase III SELVA clinical trial in microcystic lymphatic malformations and the Phase II TOIVA clinical trial in cutaneous venous malformations.
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Events Timeline

(ET)
2026-02-25
20:10:00
Deal Size Increased to $200M, Priced Below Last Close
select
2026-02-24 (ET)
2026-02-24
16:30:00
TD Cowen and Others Act as Joint Bookrunning Managers for Offering
select

News

Newsfilter
8.5
03-10Newsfilter
PinnedPalvella Launches Awareness Campaign for Microcystic Lymphatic Malformations
  • Campaign Launch: On March 10, 2026, Palvella Therapeutics announced the launch of the 'BEYOND mLM' campaign, aimed at educating and empowering over 30,000 patients with microcystic lymphatic malformations in the U.S. through the new website BEYONDmLM.com, addressing the lack of FDA-approved therapies.
  • Collaborative Efforts: The campaign is developed in partnership with several nonprofit organizations, including CaNVAS and LGDA, aiming to enhance understanding of microcystic LMs by integrating expert insights and patient stories, thereby improving quality of life and healthcare services for affected individuals.
  • Disease Impact: Microcystic lymphatic malformations are a rare and chronically debilitating condition, often leading to hospitalization due to lymph fluid leakage and recurrent infections, and Palvella's initiatives will assist patients and healthcare providers in navigating this complex condition more effectively.
  • Future Outlook: Palvella plans to foster community connections and interactions among microcystic LM patients by providing practical educational resources and support, further advancing awareness and treatment options for this condition.
Newsfilter
8.5
03-02Newsfilter
Palvella Closes $230 Million Upsized Public Offering
  • Upsized Offering: Palvella Therapeutics successfully closed its upsized public offering on February 27, 2026, issuing 1,840,000 shares of common stock, including 240,000 shares from the underwriters' full exercise of their option, at a public price of $125.00 per share, raising a total of $230 million, significantly bolstering the company's financial position.
  • Clear Use of Proceeds: The net proceeds from this offering will be allocated to support the development of programs such as QTORIN rapamycin and QTORIN pitavastatin, as well as for working capital and other general corporate purposes, indicating the company's ongoing commitment to research and development and confidence in future growth.
  • Strong Underwriting Team: The involvement of prominent financial institutions like TD Cowen, Cantor, and Stifel as joint bookrunning managers reflects market confidence in Palvella, enhancing the company's reputation in capital markets and potentially attracting more investors.
  • Regulatory Compliance: This offering was conducted under a shelf registration statement on Form S-3 that was declared effective by the SEC on January 29, 2026, ensuring compliance and increasing investor trust in the company's transparency, which may facilitate future fundraising efforts.
NASDAQ.COM
8.5
02-27NASDAQ.COM
Significant Milestones in Biotech Sector This Week
  • FDA Drug Approvals: Armata Pharmaceuticals' AP-SA02 received FDA's QIDP designation, granting five years of market exclusivity and paving the way for a Phase 3 trial in 2026, which is expected to significantly enhance the company's competitive edge in the antibiotic market.
  • Weight Loss Innovation: Allurion Technologies' gastric balloon system gained FDA approval, offering a non-surgical weight loss option for patients with a BMI of 30-40, which is anticipated to expand the company's market share in the obesity sector.
  • Acquisition Deal: Gilead Sciences is acquiring Arcellx for $115 per share, totaling $7.8 billion, a move that will strengthen Gilead's position in cell therapy and enhance its collaboration with Kite Pharma.
  • Clinical Trial Developments: Novo Nordisk's CagriSema missed key goals in its trial against Zepbound, although it demonstrated a favorable safety profile, which may influence future market strategies.
NASDAQ.COM
8.5
02-26NASDAQ.COM
Palvella Therapeutics Prices $200 Million Upsized Public Offering
  • Upsized Offering: Palvella Therapeutics has priced an upsized public offering of 1.6 million shares at $125.00 per share, expecting gross proceeds of $200 million before underwriting discounts, which will support the advancement of its QTORIN platform programs.
  • Significant Clinical Progress: The Phase 3 SELVA study for microcystic lymphatic malformations met its primary endpoint, with NDA planning underway for a potential submission in the second half of 2026, marking a breakthrough in serious skin diseases lacking FDA-approved therapies.
  • Multiple Research Initiatives: Palvella plans to initiate a Phase 2 study of QTORIN rapamycin for clinically significant angiokeratomas in the second half of 2026, alongside announcing a new QTORIN product candidate, further expanding its pipeline.
  • Strong Stock Performance: PVLA shares closed up 6.80% at $128.60 on Wednesday and rose 5% to $135.03 in premarket trading on Thursday, reflecting positive market sentiment regarding the company's future developments.
Yahoo Finance
8.5
02-26Yahoo Finance
Palvella Therapeutics Successfully Prices Upsized Public Offering
  • Upsized Offering: Palvella Therapeutics announced the pricing of its public offering of 1,600,000 shares at $125.00 per share, expecting total gross proceeds of $200 million, reflecting strong market demand for its rare disease therapies.
  • Underwriter Selection: The offering is managed by prominent financial institutions including TD Cowen, Cantor, and Stifel, which enhances investor confidence in Palvella and lays a solid foundation for future financing.
  • Clear Use of Proceeds: Palvella intends to utilize the proceeds for the development of QTORIN rapamycin and QTORIN pitavastatin, as well as for general corporate purposes, indicating the company's commitment to future product development.
  • Regulatory Compliance: The offering is conducted under an SEC S-3 registration statement, ensuring compliance throughout the process, which reduces legal risks and enhances investor trust.
Benzinga
6.0
02-25Benzinga
Wall Street Analysts Adjust Ratings
  • Analyst Rating Updates: Top Wall Street analysts have adjusted their ratings on several companies, reflecting the latest market perspectives on these stocks, which could influence investor decisions and market trends.
  • Overview of Rating Changes: While specific upgrades and downgrades are not detailed, the overall rating changes may lead to short-term volatility in related stocks, prompting investors to stay alert.
  • Expected Market Reaction: Analyst rating adjustments typically attract market attention, potentially affecting investor confidence and trading volumes, thereby impacting stock prices.
  • Impact on Investor Decisions: Investors considering buying CAVA stock should pay attention to analysts' views to make more informed investment decisions, even though specific recommendations are not provided in this article.
Wall Street analysts forecast PVLA stock price to rise
15 Analyst Rating
Wall Street analysts forecast PVLA stock price to rise
15 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
133.00
Averages
182.20
High
212.00
Current: 0.000
sliders
Low
133.00
Averages
182.20
High
212.00
Chardan
Buy
maintain
$200 -> $220
AI Analysis
2026-03-01
Reason
Chardan
Price Target
$200 -> $220
AI Analysis
2026-03-01
maintain
Buy
Reason
Chardan raised the firm's price target on Palvella Therapeutics to $220 from $200 and keeps a Buy rating on the shares. The firm says the "impressive" Phase 3 SELVA data for Qtorin rapamycin in microcystic lymphatic malformations positions Palvella for a "highly compelling label." Qtorin rapamycin is well positioned to become the first FDA-approved therapy for the 30,000-patient U.S. microcystic lymphatic malformations market, potentially capturing blockbuster status in a chronic-use population, the analyst tells investors in a research note.
Clear Street
Kaveri Pohlman
Buy
maintain
$200 -> $220
2026-03-01
Reason
Clear Street
Kaveri Pohlman
Price Target
$200 -> $220
2026-03-01
maintain
Buy
Reason
Clear Street analyst Kaveri Pohlman raised the firm's price target on Palvella Therapeutics to $220 from $200 and keeps a Buy rating on the shares. The firm says the "impressive" Phase 3 SELVA data for Qtorin rapamycin in microcystic lymphatic malformations positions Palvella for a "highly compelling label." Qtorin rapamycin is well positioned to become the first FDA-approved therapy for the 30,000-patient U.S. microcystic lymphatic malformations market, potentially capturing blockbuster status in a chronic-use population, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PVLA
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Valuation Metrics

The current forward P/E ratio for Palvella Therapeutics Inc (PVLA.O) is -25.63, compared to its 5-year average forward P/E of -13.02. For a more detailed relative valuation and DCF analysis to assess Palvella Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-13.02
Current PE
-25.63
Overvalued PE
-6.14
Undervalued PE
-19.90

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-10.23
Current EV/EBITDA
-24.36
Overvalued EV/EBITDA
-2.77
Undervalued EV/EBITDA
-17.69

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
11851.16
Current PS
53466.81
Overvalued PS
31574.16
Undervalued PS
-7871.83

Financials

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Whales Holding PVLA

F
Frazier Life Sciences Management, LP
Holding
PVLA
+9.72%
3M Return
B
BVF Partners L.P.
Holding
PVLA
+6.57%
3M Return
S
Summit Partners Public Asset Management, LLC
Holding
PVLA
+6.38%
3M Return
P
Perceptive Advisors LLC
Holding
PVLA
+6.14%
3M Return
S
Suvretta Capital Management, LLC
Holding
PVLA
+0.12%
3M Return

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Frequently Asked Questions

What is Palvella Therapeutics Inc (PVLA) stock price today?

The current price of PVLA is 138.77 USD — it has decreased -2.35

What is Palvella Therapeutics Inc (PVLA)'s business?

Palvella Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing therapies to treat patients suffering from serious, rare genetic skin diseases for which there are no FDA-approved therapies. The Company is developing a pipeline of product candidates based on its patented QTORIN platform, with an initial focus on serious, rare genetic skin diseases, many of which are lifelong in nature. Its QTORIN product candidates are developed to accommodate the cargo at high concentrations in order to drive sufficient drug to its target deep in the epidermis and dermis. The Company's lead product candidate, QTORIN 3.9% rapamycin anhydrous gel (QTORIN rapamycin), is being evaluated in the Phase III SELVA clinical trial in microcystic lymphatic malformations and the Phase II TOIVA clinical trial in cutaneous venous malformations.

What is the price predicton of PVLA Stock?

Wall Street analysts forecast PVLA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PVLA is182.20 USD with a low forecast of 133.00 USD and a high forecast of 212.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Palvella Therapeutics Inc (PVLA)'s revenue for the last quarter?

Palvella Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Palvella Therapeutics Inc (PVLA)'s earnings per share (EPS) for the last quarter?

Palvella Therapeutics Inc. EPS for the last quarter amounts to -1.03 USD, decreased -73.86

How many employees does Palvella Therapeutics Inc (PVLA). have?

Palvella Therapeutics Inc (PVLA) has 14 emplpoyees as of March 11 2026.

What is Palvella Therapeutics Inc (PVLA) market cap?

Today PVLA has the market capitalization of 1.91B USD.