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PDSB Overview

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ET
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Intellectia

Loading chart...

High
0.612
Open
0.580
VWAP
0.60
Vol
123.84K
Mkt Cap
33.84M
Low
0.580
Amount
74.48K
EV/EBITDA(TTM)
--
Total Shares
55.82M
EV
24.05M
EV/OCF(TTM)
--
P/S(TTM)
--
PDS Biotechnology Corporation is a clinical-stage immunotherapy company. The Company is developing a pipeline of targeted cancer immunotherapies based on its Versamune T cell-activator and Versamune in combination with its interleukin 12 (IL-12) fused antibody drug conjugate (ADC), PDS01ADC, a tumor targeting immunocytokine. PDS0101 is its lead Versamune based immunotherapy. PDS0101 combines Versamune with a mixture of short proteins (peptides) derived from the cancer-causing HPV16 viral protein. Versamune is a proprietary lipid nanoparticle and T cell activating platform. PDS0301 is an investigational tumor-targeting antibody conjugate of Interleukin 12 (IL-12) that enhances the proliferation, potency, infiltration, and longevity of T cells in the tumor microenvironment. Its Versamune immunotherapies and Versamune in combination with PDS01ADC, are utilized for treatments in oncology, and Infectimune is utilized for preventive vaccines against infectious agents.
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Events Timeline

(ET)
2026-02-20
08:40:00
PDS Biotechnology Amends VERSATILE-003 Clinical Trial Protocol
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2026-01-28 (ET)
2026-01-28
09:00:00
PDS Biotechnology Presents PDS01ADC Study Results at AACR Conference
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2026-01-22 (ET)
2026-01-22
08:50:00
PDS Biotechnology Receives Patent Allowance for PDS0101 Development
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2026-01-09 (ET)
2026-01-09
08:50:00
PDS Biotechnology Submits Protocol Amendment for VERSATILE-003 Trial to FDA
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2025-12-02 (ET)
2025-12-02
08:40:00
PDS Biotechnology Secures FDA Meeting to Discuss Accelerated Approval for PDS0101
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2025-11-13 (ET)
2025-11-13
07:34:39
PDS Biotechnology announces Q3 earnings per share of 19 cents, below consensus estimate of 20 cents.
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2025-11-11 (ET)
2025-11-11
15:34:26
PDS Biotechnology reveals registered direct offering of up to $11.1 million
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News

Yahoo Finance
9.5
03-31Yahoo Finance
PinnedPDS Biotechnology Reports 2025 Financial Results with Strategic Developments
  • Financial Performance: PDS Biotechnology reported a net loss of $34.5 million for 2025, translating to a basic and diluted loss of $0.74 per share, indicating ongoing financial challenges despite a reduction from the previous year's loss of $37.6 million.
  • R&D Expenses: The company incurred $19 million in research and development expenses in 2025, down from $22.6 million in 2024, reflecting the significant costs associated with advancing clinical trials, yet future spending trends remain a concern.
  • Cash Position: As of December 31, 2025, PDSB's cash balance stood at $26.7 million, which may limit its financial flexibility moving forward, particularly as further investments in R&D are anticipated.
  • Clinical Advancements: PDS Biotechnology has made significant progress with the amendment of the VERSATILE-003 trial, which is expected to lead to a more efficient path to accelerated approval, although uncertainties regarding the exact enrollment targets and sample size persist.
seekingalpha
9.5
03-30seekingalpha
PDS Biotechnology Corporation Q4 2025 Earnings Call Insights
  • Significant Clinical Progress: PDS Biotechnology's Q4 2025 earnings report highlights that the amendment to the VERSATILE-003 protocol is expected to shorten trial duration and reduce costs, thereby accelerating regulatory submission while maintaining overall survival as the basis for approval, showcasing the company's innovative capabilities in clinical trial design.
  • Decrease in R&D Expenses: Research and development expenses for 2025 were reported at $19 million, down from $22.6 million in 2024, primarily due to reductions in manufacturing and personnel costs, reflecting effective financial management while leaving room for future investments.
  • Enhanced Intellectual Property Protection: The company secured new patents for PDS0101 in the U.S. and Japan, extending market protection into the 2040s, indicating that PDS Biotechnology's strategic positioning in intellectual property will support its long-term market potential.
  • Optimistic Outlook: Although management did not provide specific financial guidance, they expressed optimism regarding the amendment of the VERSATILE-003 trial and future patient enrollment, which is expected to lead to a faster regulatory path and potential market opportunities.
seekingalpha
9.5
03-30seekingalpha
PDS Biotechnology Reports FY 2025 Financial Results
  • Financial Performance: PDS Biotechnology reported a GAAP EPS of -$0.74 for FY 2025, indicating challenges in profitability that could impact investor confidence and exert downward pressure on stock prices.
  • Cash Position: As of December 31, 2025, the company had a cash balance of $26.7 million, which, while providing some liquidity, raises concerns about capital efficiency and potential future financing needs.
  • Market Reaction: The reported losses may lead to a cautious market outlook for PDS Biotechnology, prompting investors to closely monitor subsequent strategic adjustments and financial improvement initiatives.
  • Future Outlook: The company must implement effective measures to enhance profitability in order to navigate market competition and achieve sustainable growth, particularly in the context of rapid advancements in the biotechnology sector.
seekingalpha
9.5
03-29seekingalpha
PDS Biotechnology Set to Release FY Earnings
  • Earnings Announcement: PDS Biotechnology is set to announce its FY earnings on March 30th after market close, with investors keenly awaiting the results to gauge the company's future growth potential.
  • EPS Expectations: The consensus EPS estimate stands at -$0.80, reflecting a 22.3% year-over-year improvement, indicating the company's efforts to enhance profitability despite still being in a loss position.
  • Revenue Forecast: The consensus revenue estimate for PDS Biotechnology is $0, highlighting the challenges the company faces in revenue growth, which could impact investor confidence.
  • Quant Rating Insight: Seeking Alpha's Quant Rating on PDS Biotechnology provides market analysis perspectives, aiding investors in better understanding the company's financial health and competitive position in the biotech sector.
Newsfilter
9.0
02-20Newsfilter
PDS Biotechnology Amends Phase 3 Trial Protocol for Accelerated Approval
  • Protocol Amendment: PDS Biotechnology Corporation announced an amendment to its Phase 3 VERSATILE-003 clinical trial protocol, adding progression-free survival (PFS) as an interim primary endpoint to support a potential accelerated approval pathway for PDS0101 in HPV16-positive recurrent and/or metastatic head and neck cancer.
  • Survival Endpoint Maintained: While PFS is added as an interim endpoint, the median overall survival (mOS) remains the primary endpoint, ensuring consistency with prior regulatory dialogues with the FDA, thereby enhancing the company's confidence in the regulatory approval process.
  • Accelerated Approval Potential: By including PFS as an interim primary endpoint, the trial duration is expected to shorten, accelerating the timeline for regulatory submission while improving cost efficiency, further advancing the company's strategic positioning in cancer immunotherapy.
  • Optimistic Market Outlook: PDS0101, as a targeted immunotherapy for HPV16-positive recurrent and/or metastatic head and neck cancer, developed in combination with standard immune checkpoint inhibitors, demonstrates strong market potential, aligning with the growing patient demand.
PRnewswire
8.5
01-12PRnewswire
Oncolytics Biotech Advances Pelareorep for Anal Cancer with 29% Response Rate
  • Clinical Data Breakthrough: Oncolytics Biotech's pelareorep demonstrated a 29% objective response rate in anal cancer during the GOBLET Cohort 4, significantly exceeding the historical benchmark of 10%, indicating its crucial clinical value in a setting with no FDA-approved treatment options.
  • Duration of Response: Among 14 evaluable patients, the median duration of response for pelareorep reached approximately 17 months, far surpassing the standard treatment's 9.5 months, showcasing the drug's durable efficacy in heavily pretreated patients and addressing a critical unmet medical need.
  • FDA Accelerated Approval Plans: Oncolytics plans to hold a Type C meeting with the FDA in Q1 2026 to discuss advancing pelareorep into a registration-directed clinical study, paving the way for potential accelerated approval if the data is validated.
  • Strategic Investment and Expert Support: The company expanded its Scientific Advisory Board by adding three globally recognized experts from Memorial Sloan Kettering Cancer Center and MD Anderson Cancer Center, further strengthening its strategic positioning in the gastrointestinal oncology field.
Wall Street analysts forecast PDSB stock price to rise
2 Analyst Rating
Wall Street analysts forecast PDSB stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
3.00
Averages
9.00
High
15.00
Current: 0.000
sliders
Low
3.00
Averages
9.00
High
15.00
B. Riley
Buy
downgrade
$5 -> $3
AI Analysis
2025-11-25
Reason
B. Riley
Price Target
$5 -> $3
AI Analysis
2025-11-25
downgrade
Buy
Reason
B. Riley lowered the firm's price target on PDS Biotechnology to $3 from $5 and keeps a Buy rating on the shares. The shares remain attractively valued with near-zero EV that fails to reflect impact of this recent strategic pivot on enrollment size, efficacy endpoint durations and an enriched p16+ve population with limited competing trials, the analyst tells investors in a research note.
H.C. Wainwright
Buy
maintain
$13 -> $15
2025-11-13
Reason
H.C. Wainwright
Price Target
$13 -> $15
2025-11-13
maintain
Buy
Reason
H.C. Wainwright raised the firm's price target on PDS Biotechnology to $15 from $13 and keeps a Buy rating on the shares. The firm is increasing its view of the probability of success for PDS0101 in head and neck cancer to 65% from 40% following the most recent median overall survival data from the VERSATILE-002 study, the analyst tells investors.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PDSB
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Valuation Metrics

The current forward P/E ratio for PDS Biotechnology Corp (PDSB.O) is 0.00, compared to its 5-year average forward P/E of -4.77. For a more detailed relative valuation and DCF analysis to assess PDS Biotechnology Corp's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.77
Current PE
0.00
Overvalued PE
-0.34
Undervalued PE
-9.19

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.57
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.29
Undervalued EV/EBITDA
-7.42

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
90.60
Current PS
0.00
Overvalued PS
475.69
Undervalued PS
-294.50

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Frequently Asked Questions

What is PDS Biotechnology Corp (PDSB) stock price today?

The current price of PDSB is 0.6121 USD — it has increased 0.99

What is PDS Biotechnology Corp (PDSB)'s business?

PDS Biotechnology Corporation is a clinical-stage immunotherapy company. The Company is developing a pipeline of targeted cancer immunotherapies based on its Versamune T cell-activator and Versamune in combination with its interleukin 12 (IL-12) fused antibody drug conjugate (ADC), PDS01ADC, a tumor targeting immunocytokine. PDS0101 is its lead Versamune based immunotherapy. PDS0101 combines Versamune with a mixture of short proteins (peptides) derived from the cancer-causing HPV16 viral protein. Versamune is a proprietary lipid nanoparticle and T cell activating platform. PDS0301 is an investigational tumor-targeting antibody conjugate of Interleukin 12 (IL-12) that enhances the proliferation, potency, infiltration, and longevity of T cells in the tumor microenvironment. Its Versamune immunotherapies and Versamune in combination with PDS01ADC, are utilized for treatments in oncology, and Infectimune is utilized for preventive vaccines against infectious agents.

What is the price predicton of PDSB Stock?

Wall Street analysts forecast PDSB stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PDSB is9.00 USD with a low forecast of 3.00 USD and a high forecast of 15.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is PDS Biotechnology Corp (PDSB)'s revenue for the last quarter?

PDS Biotechnology Corp revenue for the last quarter amounts to -6.67M USD, decreased -9.32

What is PDS Biotechnology Corp (PDSB)'s earnings per share (EPS) for the last quarter?

PDS Biotechnology Corp. EPS for the last quarter amounts to -3702585.00 USD, decreased -55.04

How many employees does PDS Biotechnology Corp (PDSB). have?

PDS Biotechnology Corp (PDSB) has 21 emplpoyees as of April 02 2026.

What is PDS Biotechnology Corp (PDSB) market cap?

Today PDSB has the market capitalization of 33.84M USD.