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PDSB Overview

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ET
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Intellectia

Loading chart...

High
1.040
Open
1.015
VWAP
0.99
Vol
518.41K
Mkt Cap
53.60M
Low
0.962
Amount
514.20K
EV/EBITDA(TTM)
--
Total Shares
55.82M
EV
43.81M
EV/OCF(TTM)
--
P/S(TTM)
--
PDS Biotechnology Corporation is a clinical-stage immunotherapy company. The Company is developing a pipeline of targeted cancer immunotherapies based on its Versamune T cell-activator and Versamune in combination with its interleukin 12 (IL-12) fused antibody drug conjugate (ADC), PDS01ADC, a tumor targeting immunocytokine. PDS0101 is its lead Versamune based immunotherapy. PDS0101 combines Versamune with a mixture of short proteins (peptides) derived from the cancer-causing HPV16 viral protein. Versamune is a proprietary lipid nanoparticle and T cell activating platform. PDS0301 is an investigational tumor-targeting antibody conjugate of Interleukin 12 (IL-12) that enhances the proliferation, potency, infiltration, and longevity of T cells in the tumor microenvironment. Its Versamune immunotherapies and Versamune in combination with PDS01ADC, are utilized for treatments in oncology, and Infectimune is utilized for preventive vaccines against infectious agents.
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Events Timeline

(ET)
2026-04-15
09:40:00
PDS Biotechnology Publishes Clinical Data for PDS01ADC
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2026-02-20 (ET)
2026-02-20
08:40:00
PDS Biotechnology Amends VERSATILE-003 Clinical Trial Protocol
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2026-01-28 (ET)
2026-01-28
09:00:00
PDS Biotechnology Presents PDS01ADC Study Results at AACR Conference
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2026-01-22 (ET)
2026-01-22
08:50:00
PDS Biotechnology Receives Patent Allowance for PDS0101 Development
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2026-01-09 (ET)
2026-01-09
08:50:00
PDS Biotechnology Submits Protocol Amendment for VERSATILE-003 Trial to FDA
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2025-12-02 (ET)
2025-12-02
08:40:00
PDS Biotechnology Secures FDA Meeting to Discuss Accelerated Approval for PDS0101
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2025-11-13 (ET)
2025-11-13
07:34:39
PDS Biotechnology announces Q3 earnings per share of 19 cents, below consensus estimate of 20 cents.
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News

NASDAQ.COM
9.0
04-16NASDAQ.COM
PDS Biotechnology Reports Positive Phase 2 Results for Cancer Therapy
  • Clinical Trial Results: PDS Biotechnology's Phase 2 trial led by NCI shows a 77.8% objective response rate for its IL-12 immunocytokine PDS01ADC in metastatic colorectal cancer, significantly outperforming the 35% rate in the control group, indicating strong efficacy.
  • Survival Rate Improvement: The two-year survival rate for patients reached approximately 85%, compared to 40% in the control group, suggesting that PDS01ADC could significantly enhance patient survival and potentially redefine treatment standards.
  • Progression-Free Survival: With a median follow-up of 13.1 months, the median progression-free survival has not yet been reached, indicating potential long-term efficacy, especially when compared to the control group's 8.1 months, highlighting a promising treatment outlook.
  • Innovative Treatment Mechanism: PDS01ADC combines subcutaneous administration with hepatic artery infusion of FUDR to concentrate IL-12 at tumor sites, enhancing anti-tumor potency and tolerability, which may provide new avenues for cancer treatment in the future.
stocktwits
2.0
04-15stocktwits
PDS Biotechnology's Cancer Therapy Trial Shows Promising Results
  • Clinical Trial Results: PDS Biotechnology's PDS01ADC achieved an objective response rate (ORR) of nearly 78% in a Phase 2 trial for patients with microsatellite-stable or mismatch repair-proficient metastatic colorectal cancer with liver metastases, significantly outperforming the 35% ORR seen in a similar trial without the drug, indicating strong efficacy.
  • Survival Rate Improvement: The trial reported a two-year survival rate exceeding 80%, more than double the 35% to 40% survival rate of the comparison group, suggesting that this therapy could significantly enhance patient outcomes and potentially redefine treatment standards.
  • Positive Stock Reaction: Following the trial results announcement, PDS Biotechnology's shares surged 24% on Wednesday, reaching their highest levels since August 27, 2025, reflecting strong market confidence in the new therapy and positive investor sentiment.
  • Future Development Prospects: The company also updated its Phase 3 VERSATILE-003 trial last month by adding progression-free survival as a primary endpoint, which could expedite the approval of PDS0101 for HPV16-related head and neck cancer, further enhancing market expectations for its future growth.
Yahoo Finance
9.5
03-31Yahoo Finance
PDS Biotechnology Reports 2025 Financial Results with Strategic Developments
  • Financial Performance: PDS Biotechnology reported a net loss of $34.5 million for 2025, translating to a basic and diluted loss of $0.74 per share, indicating ongoing financial challenges despite a reduction from the previous year's loss of $37.6 million.
  • R&D Expenses: The company incurred $19 million in research and development expenses in 2025, down from $22.6 million in 2024, reflecting the significant costs associated with advancing clinical trials, yet future spending trends remain a concern.
  • Cash Position: As of December 31, 2025, PDSB's cash balance stood at $26.7 million, which may limit its financial flexibility moving forward, particularly as further investments in R&D are anticipated.
  • Clinical Advancements: PDS Biotechnology has made significant progress with the amendment of the VERSATILE-003 trial, which is expected to lead to a more efficient path to accelerated approval, although uncertainties regarding the exact enrollment targets and sample size persist.
seekingalpha
9.5
03-30seekingalpha
PDS Biotechnology Corporation Q4 2025 Earnings Call Insights
  • Significant Clinical Progress: PDS Biotechnology's Q4 2025 earnings report highlights that the amendment to the VERSATILE-003 protocol is expected to shorten trial duration and reduce costs, thereby accelerating regulatory submission while maintaining overall survival as the basis for approval, showcasing the company's innovative capabilities in clinical trial design.
  • Decrease in R&D Expenses: Research and development expenses for 2025 were reported at $19 million, down from $22.6 million in 2024, primarily due to reductions in manufacturing and personnel costs, reflecting effective financial management while leaving room for future investments.
  • Enhanced Intellectual Property Protection: The company secured new patents for PDS0101 in the U.S. and Japan, extending market protection into the 2040s, indicating that PDS Biotechnology's strategic positioning in intellectual property will support its long-term market potential.
  • Optimistic Outlook: Although management did not provide specific financial guidance, they expressed optimism regarding the amendment of the VERSATILE-003 trial and future patient enrollment, which is expected to lead to a faster regulatory path and potential market opportunities.
seekingalpha
9.5
03-30seekingalpha
PDS Biotechnology Reports FY 2025 Financial Results
  • Financial Performance: PDS Biotechnology reported a GAAP EPS of -$0.74 for FY 2025, indicating challenges in profitability that could impact investor confidence and exert downward pressure on stock prices.
  • Cash Position: As of December 31, 2025, the company had a cash balance of $26.7 million, which, while providing some liquidity, raises concerns about capital efficiency and potential future financing needs.
  • Market Reaction: The reported losses may lead to a cautious market outlook for PDS Biotechnology, prompting investors to closely monitor subsequent strategic adjustments and financial improvement initiatives.
  • Future Outlook: The company must implement effective measures to enhance profitability in order to navigate market competition and achieve sustainable growth, particularly in the context of rapid advancements in the biotechnology sector.
seekingalpha
9.5
03-29seekingalpha
PDS Biotechnology Set to Release FY Earnings
  • Earnings Announcement: PDS Biotechnology is set to announce its FY earnings on March 30th after market close, with investors keenly awaiting the results to gauge the company's future growth potential.
  • EPS Expectations: The consensus EPS estimate stands at -$0.80, reflecting a 22.3% year-over-year improvement, indicating the company's efforts to enhance profitability despite still being in a loss position.
  • Revenue Forecast: The consensus revenue estimate for PDS Biotechnology is $0, highlighting the challenges the company faces in revenue growth, which could impact investor confidence.
  • Quant Rating Insight: Seeking Alpha's Quant Rating on PDS Biotechnology provides market analysis perspectives, aiding investors in better understanding the company's financial health and competitive position in the biotech sector.
Wall Street analysts forecast PDSB stock price to rise
2 Analyst Rating
Wall Street analysts forecast PDSB stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
3.00
Averages
9.00
High
15.00
Current: 0.000
sliders
Low
3.00
Averages
9.00
High
15.00
B. Riley
Buy
downgrade
$5 -> $3
AI Analysis
2025-11-25
Reason
B. Riley
Price Target
$5 -> $3
AI Analysis
2025-11-25
downgrade
Buy
Reason
B. Riley lowered the firm's price target on PDS Biotechnology to $3 from $5 and keeps a Buy rating on the shares. The shares remain attractively valued with near-zero EV that fails to reflect impact of this recent strategic pivot on enrollment size, efficacy endpoint durations and an enriched p16+ve population with limited competing trials, the analyst tells investors in a research note.
H.C. Wainwright
Buy
maintain
$13 -> $15
2025-11-13
Reason
H.C. Wainwright
Price Target
$13 -> $15
2025-11-13
maintain
Buy
Reason
H.C. Wainwright raised the firm's price target on PDS Biotechnology to $15 from $13 and keeps a Buy rating on the shares. The firm is increasing its view of the probability of success for PDS0101 in head and neck cancer to 65% from 40% following the most recent median overall survival data from the VERSATILE-002 study, the analyst tells investors.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PDSB
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Valuation Metrics

The current forward P/E ratio for PDS Biotechnology Corp (PDSB.O) is 0.00, compared to its 5-year average forward P/E of -4.72. For a more detailed relative valuation and DCF analysis to assess PDS Biotechnology Corp's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.72
Current PE
0.00
Overvalued PE
-0.27
Undervalued PE
-9.16

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.54
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.35
Undervalued EV/EBITDA
-7.43

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
92.15
Current PS
0.00
Overvalued PS
480.35
Undervalued PS
-296.05

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Frequently Asked Questions

What is PDS Biotechnology Corp (PDSB) stock price today?

The current price of PDSB is 0.973 USD — it has increased 1.35

What is PDS Biotechnology Corp (PDSB)'s business?

PDS Biotechnology Corporation is a clinical-stage immunotherapy company. The Company is developing a pipeline of targeted cancer immunotherapies based on its Versamune T cell-activator and Versamune in combination with its interleukin 12 (IL-12) fused antibody drug conjugate (ADC), PDS01ADC, a tumor targeting immunocytokine. PDS0101 is its lead Versamune based immunotherapy. PDS0101 combines Versamune with a mixture of short proteins (peptides) derived from the cancer-causing HPV16 viral protein. Versamune is a proprietary lipid nanoparticle and T cell activating platform. PDS0301 is an investigational tumor-targeting antibody conjugate of Interleukin 12 (IL-12) that enhances the proliferation, potency, infiltration, and longevity of T cells in the tumor microenvironment. Its Versamune immunotherapies and Versamune in combination with PDS01ADC, are utilized for treatments in oncology, and Infectimune is utilized for preventive vaccines against infectious agents.

What is the price predicton of PDSB Stock?

Wall Street analysts forecast PDSB stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PDSB is9.00 USD with a low forecast of 3.00 USD and a high forecast of 15.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is PDS Biotechnology Corp (PDSB)'s revenue for the last quarter?

PDS Biotechnology Corp revenue for the last quarter amounts to -6.67M USD, decreased -9.32

What is PDS Biotechnology Corp (PDSB)'s earnings per share (EPS) for the last quarter?

PDS Biotechnology Corp. EPS for the last quarter amounts to -3702585.00 USD, decreased -55.04

How many employees does PDS Biotechnology Corp (PDSB). have?

PDS Biotechnology Corp (PDSB) has 21 emplpoyees as of May 01 2026.

What is PDS Biotechnology Corp (PDSB) market cap?

Today PDSB has the market capitalization of 53.60M USD.