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PDSB Overview

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ET
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Intellectia

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High
1.280
Open
1.190
VWAP
1.22
Vol
1.17M
Mkt Cap
66.98M
Low
1.180
Amount
1.42M
EV/EBITDA(TTM)
--
Total Shares
55.82M
EV
61.18M
EV/OCF(TTM)
--
P/S(TTM)
--
PDS Biotechnology Corporation is a clinical-stage immunotherapy company. The Company is developing a pipeline of targeted cancer immunotherapies based on its Versamune T cell-activator and Versamune in combination with its interleukin 12 (IL-12) fused antibody drug conjugate (ADC), PDS01ADC, a tumor targeting immunocytokine. PDS0101 is its lead Versamune based immunotherapy. PDS0101 combines Versamune with a mixture of short proteins (peptides) derived from the cancer-causing HPV16 viral protein. Versamune is a proprietary lipid nanoparticle and T cell activating platform. PDS0301 is an investigational tumor-targeting antibody conjugate of Interleukin 12 (IL-12) that enhances the proliferation, potency, infiltration, and longevity of T cells in the tumor microenvironment. Its Versamune immunotherapies and Versamune in combination with PDS01ADC, are utilized for treatments in oncology, and Infectimune is utilized for preventive vaccines against infectious agents.
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Events Timeline

(ET)
2026-04-15
09:40:00
PDS Biotechnology Publishes Clinical Data for PDS01ADC
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2026-02-20 (ET)
2026-02-20
08:40:00
PDS Biotechnology Amends VERSATILE-003 Clinical Trial Protocol
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2026-01-28 (ET)
2026-01-28
09:00:00
PDS Biotechnology Presents PDS01ADC Study Results at AACR Conference
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2026-01-22 (ET)
2026-01-22
08:50:00
PDS Biotechnology Receives Patent Allowance for PDS0101 Development
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2026-01-09 (ET)
2026-01-09
08:50:00
PDS Biotechnology Submits Protocol Amendment for VERSATILE-003 Trial to FDA
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2025-12-02 (ET)
2025-12-02
08:40:00
PDS Biotechnology Secures FDA Meeting to Discuss Accelerated Approval for PDS0101
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2025-11-13 (ET)
2025-11-13
07:34:39
PDS Biotechnology announces Q3 earnings per share of 19 cents, below consensus estimate of 20 cents.
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News

seekingalpha
9.5
05-13seekingalpha
PDS Biotechnology Q1 2026 Earnings Call Insights
  • Clinical Trial Progress: PDS Biotechnology focused on advancing clinical programs in Q1 2026, with CMO Dr. Kirk Shepard noting an amendment to the VERSATILE-003 study design that incorporates progression-free survival as an interim primary endpoint, which is expected to facilitate a more efficient approval pathway and reduce overall costs.
  • Enhanced Patent Protection: The new U.S. patent for PDS0101, combined with anticipated biologics exclusivity, extends market protection into the 2040s, strengthening its competitive position in the HPV16-positive head and neck cancer market.
  • Financial Performance: As of March 31, 2026, PDS Biotechnology reported a net loss of approximately $7.3 million, or $0.13 per share, with R&D expenses at $3.5 million and total operating expenses at $6.5 million, indicating a continued commitment to R&D investment.
  • Future Outlook: Management anticipates additional patient data on colorectal cancer studies by year-end, while emphasizing alignment with the FDA and plans to restart VERSATILE-003 enrollment in the near future, reflecting confidence in clinical advancements.
seekingalpha
9.5
05-13seekingalpha
PDS Biotechnology Reports Q1 Earnings Results
  • Earnings Performance: PDS Biotechnology reported a Q1 GAAP EPS of -$0.13, indicating ongoing challenges in profitability that may affect investor confidence and stock performance.
  • Cash Reserves: As of March 31, 2026, the company had a cash balance of $21.7 million, which, while providing some liquidity, raises concerns about the sustainability of operational funding and future investment capabilities.
  • Regulatory Progress: Following the amendment of the VERSATILE-003 protocol, PDS Biotechnology outlined an accelerated regulatory timeline, demonstrating a proactive approach to product development and market access that could pave the way for future revenue growth.
  • Market Attention: With the financial performance and regulatory advancements of PDS Biotechnology, market interest in the company's future prospects is increasing, prompting investors to closely monitor subsequent financial and operational developments.
seekingalpha
9.5
05-12seekingalpha
PDS Biotechnology to Announce Q1 Earnings on May 13
  • Earnings Announcement Date: PDS Biotechnology is set to release its Q1 earnings report on May 13 before the market opens, with investors keenly awaiting the financial results to assess the company's future growth potential.
  • EPS Expectations: The consensus EPS estimate stands at -$0.14, reflecting a 33.3% year-over-year improvement, indicating that while still negative, the company shows signs of improving profitability.
  • Revenue Forecast: The revenue estimate for the first quarter is projected at $0, highlighting ongoing challenges in revenue generation, which may affect investor confidence in the company's growth prospects.
  • Estimate Revision Trends: Over the past three months, there has been one upward revision and no downward adjustments to EPS estimates, suggesting a cautiously optimistic outlook from analysts that could influence stock price movements.
NASDAQ.COM
9.0
04-16NASDAQ.COM
PDS Biotechnology Reports Positive Phase 2 Results for Cancer Therapy
  • Clinical Trial Results: PDS Biotechnology's Phase 2 trial led by NCI shows a 77.8% objective response rate for its IL-12 immunocytokine PDS01ADC in metastatic colorectal cancer, significantly outperforming the 35% rate in the control group, indicating strong efficacy.
  • Survival Rate Improvement: The two-year survival rate for patients reached approximately 85%, compared to 40% in the control group, suggesting that PDS01ADC could significantly enhance patient survival and potentially redefine treatment standards.
  • Progression-Free Survival: With a median follow-up of 13.1 months, the median progression-free survival has not yet been reached, indicating potential long-term efficacy, especially when compared to the control group's 8.1 months, highlighting a promising treatment outlook.
  • Innovative Treatment Mechanism: PDS01ADC combines subcutaneous administration with hepatic artery infusion of FUDR to concentrate IL-12 at tumor sites, enhancing anti-tumor potency and tolerability, which may provide new avenues for cancer treatment in the future.
stocktwits
2.0
04-15stocktwits
PDS Biotechnology's Cancer Therapy Trial Shows Promising Results
  • Clinical Trial Results: PDS Biotechnology's PDS01ADC achieved an objective response rate (ORR) of nearly 78% in a Phase 2 trial for patients with microsatellite-stable or mismatch repair-proficient metastatic colorectal cancer with liver metastases, significantly outperforming the 35% ORR seen in a similar trial without the drug, indicating strong efficacy.
  • Survival Rate Improvement: The trial reported a two-year survival rate exceeding 80%, more than double the 35% to 40% survival rate of the comparison group, suggesting that this therapy could significantly enhance patient outcomes and potentially redefine treatment standards.
  • Positive Stock Reaction: Following the trial results announcement, PDS Biotechnology's shares surged 24% on Wednesday, reaching their highest levels since August 27, 2025, reflecting strong market confidence in the new therapy and positive investor sentiment.
  • Future Development Prospects: The company also updated its Phase 3 VERSATILE-003 trial last month by adding progression-free survival as a primary endpoint, which could expedite the approval of PDS0101 for HPV16-related head and neck cancer, further enhancing market expectations for its future growth.
Yahoo Finance
9.5
03-31Yahoo Finance
PDS Biotechnology Reports 2025 Financial Results with Strategic Developments
  • Financial Performance: PDS Biotechnology reported a net loss of $34.5 million for 2025, translating to a basic and diluted loss of $0.74 per share, indicating ongoing financial challenges despite a reduction from the previous year's loss of $37.6 million.
  • R&D Expenses: The company incurred $19 million in research and development expenses in 2025, down from $22.6 million in 2024, reflecting the significant costs associated with advancing clinical trials, yet future spending trends remain a concern.
  • Cash Position: As of December 31, 2025, PDSB's cash balance stood at $26.7 million, which may limit its financial flexibility moving forward, particularly as further investments in R&D are anticipated.
  • Clinical Advancements: PDS Biotechnology has made significant progress with the amendment of the VERSATILE-003 trial, which is expected to lead to a more efficient path to accelerated approval, although uncertainties regarding the exact enrollment targets and sample size persist.
Wall Street analysts forecast PDSB stock price to rise
2 Analyst Rating
Wall Street analysts forecast PDSB stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
3.00
Averages
9.00
High
15.00
Current: 0.000
sliders
Low
3.00
Averages
9.00
High
15.00
B. Riley
Buy
downgrade
$5 -> $3
AI Analysis
2025-11-25
Reason
B. Riley
Price Target
$5 -> $3
AI Analysis
2025-11-25
downgrade
Buy
Reason
B. Riley lowered the firm's price target on PDS Biotechnology to $3 from $5 and keeps a Buy rating on the shares. The shares remain attractively valued with near-zero EV that fails to reflect impact of this recent strategic pivot on enrollment size, efficacy endpoint durations and an enriched p16+ve population with limited competing trials, the analyst tells investors in a research note.
H.C. Wainwright
Buy
maintain
$13 -> $15
2025-11-13
Reason
H.C. Wainwright
Price Target
$13 -> $15
2025-11-13
maintain
Buy
Reason
H.C. Wainwright raised the firm's price target on PDS Biotechnology to $15 from $13 and keeps a Buy rating on the shares. The firm is increasing its view of the probability of success for PDS0101 in head and neck cancer to 65% from 40% following the most recent median overall survival data from the VERSATILE-002 study, the analyst tells investors.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PDSB
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Valuation Metrics

The current forward P/E ratio for PDS Biotechnology Corp (PDSB.O) is 0.00, compared to its 5-year average forward P/E of -4.68. For a more detailed relative valuation and DCF analysis to assess PDS Biotechnology Corp's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.68
Current PE
0.00
Overvalued PE
-0.22
Undervalued PE
-9.14

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.52
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.38
Undervalued EV/EBITDA
-7.42

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
93.35
Current PS
0.00
Overvalued PS
483.93
Undervalued PS
-297.22

Financials

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Frequently Asked Questions

What is PDS Biotechnology Corp (PDSB) stock price today?

The current price of PDSB is 1.2 USD — it has increased 3.45

What is PDS Biotechnology Corp (PDSB)'s business?

PDS Biotechnology Corporation is a clinical-stage immunotherapy company. The Company is developing a pipeline of targeted cancer immunotherapies based on its Versamune T cell-activator and Versamune in combination with its interleukin 12 (IL-12) fused antibody drug conjugate (ADC), PDS01ADC, a tumor targeting immunocytokine. PDS0101 is its lead Versamune based immunotherapy. PDS0101 combines Versamune with a mixture of short proteins (peptides) derived from the cancer-causing HPV16 viral protein. Versamune is a proprietary lipid nanoparticle and T cell activating platform. PDS0301 is an investigational tumor-targeting antibody conjugate of Interleukin 12 (IL-12) that enhances the proliferation, potency, infiltration, and longevity of T cells in the tumor microenvironment. Its Versamune immunotherapies and Versamune in combination with PDS01ADC, are utilized for treatments in oncology, and Infectimune is utilized for preventive vaccines against infectious agents.

What is the price predicton of PDSB Stock?

Wall Street analysts forecast PDSB stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PDSB is9.00 USD with a low forecast of 3.00 USD and a high forecast of 15.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is PDS Biotechnology Corp (PDSB)'s revenue for the last quarter?

PDS Biotechnology Corp revenue for the last quarter amounts to -6.52M USD, decreased -28.39

What is PDS Biotechnology Corp (PDSB)'s earnings per share (EPS) for the last quarter?

PDS Biotechnology Corp. EPS for the last quarter amounts to USD, decreased

How many employees does PDS Biotechnology Corp (PDSB). have?

PDS Biotechnology Corp (PDSB) has 21 emplpoyees as of May 24 2026.

What is PDS Biotechnology Corp (PDSB) market cap?

Today PDSB has the market capitalization of 66.98M USD.