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NTLA Should I Buy

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Intellectia

Should You Buy Intellia Therapeutics Inc (NTLA) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
13.470
1 Day change
-3.02%
52 Week Range
28.250
Analysis Updated At
2026/03/06
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Intellia Therapeutics Inc (NTLA) is not a strong buy at this moment for a beginner, long-term investor with $50,000-$100,000 to invest. While the company has positive regulatory developments and analyst upgrades, the pre-market price is showing a slight decline (-0.99%), insider selling is significantly high, and financial performance shows declining net income and EPS. Additionally, there are no strong proprietary trading signals to suggest immediate action. The stock may be worth monitoring for future entry points, but it does not currently meet the criteria for a compelling buy.

Technical Analysis

The MACD is positive but contracting, indicating weakening momentum. RSI is neutral at 44.74, and moving averages are bullish (SMA_5 > SMA_20 > SMA_200). Key support is at 12.681, and resistance is at 15.054. The stock is trading below the pivot level of 13.867, suggesting limited upward momentum in the short term.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

The low put-call ratios indicate a bullish sentiment in the options market, but the implied volatility percentile (24.3) and IV rank (17.18) suggest limited potential for significant price movement.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
5
Buy
7

Positive Catalysts

  • The FDA has lifted clinical holds on the MAGNITUDE Phase 3 study, which is a significant regulatory milestone. Analysts have responded positively, with multiple upgrades and increased price targets. Revenue increased by 78.79% YoY in Q4 2025.

Neutral/Negative Catalysts

  • Insider selling has surged by 2235.78% over the last month, which could indicate a lack of confidence from company insiders. Net income and EPS have both declined significantly YoY. The pre-market price is down 0.99%, and there are no recent proprietary trading signals to suggest immediate upside potential.

Financial Performance

In Q4 2025, revenue increased by 78.79% YoY to $23.02M, but net income dropped by 25.69% YoY to -$95.79M, and EPS fell by 34.65% YoY to -$0.83. Gross margin remained stable at 100%. While revenue growth is strong, profitability metrics are deteriorating.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts have shown optimism with multiple upgrades and increased price targets, ranging from $15 to $48. The FDA's lifting of clinical holds has been viewed as a major win, but some analysts remain cautious about safety concerns and market competition.

Wall Street analysts forecast NTLA stock price to rise
22 Analyst Rating
Wall Street analysts forecast NTLA stock price to rise
9 Buy
12 Hold
1 Sell
Moderate Buy
Current: 13.890
sliders
Low
4
Averages
16.5
High
54
Current: 13.890
sliders
Low
4
Averages
16.5
High
54
JonesResearch
Hold
to
Buy
upgrade
$29
AI Analysis
2026-03-04
Reason
JonesResearch
Price Target
$29
AI Analysis
2026-03-04
upgrade
Hold
to
Buy
Reason
JonesResearch upgraded Intellia Therapeutics to Buy from Hold with a $29 price target. The The FDA removed the hold on both MAGNITUDE and MAGNITUDE-2 studies, with Intellia reactivating sites to continue enrollment, the analyst tells investors in a research note. The firm says clarity around the cause of death being likely unrelated to nex-z and favorable regulatory updates reinstate its bullish view on the shares.
BofA
Alec Stranahan
Neutral
maintain
$17 -> $19
2026-03-03
Reason
BofA
Alec Stranahan
Price Target
$17 -> $19
2026-03-03
maintain
Neutral
Reason
BofA analyst Alec Stranahan raised the firm's price target on Intellia Therapeutics to $19 from $17 and keeps a Neutral rating on the shares. The FDA has removed the clinical hold on the MAGNITUDE Phase 3 study in transthyretin amyloidosis-cardiomyopathy for nex-z, re-opening the "larger value driver in the franchise," the analyst tells investors. Following the news, the firm increased its view of the probability of success in ATTR-CM to 55% from 38%.
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