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LONA Overview

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0.000
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Intellectia

Loading chart...

High
9.980
Open
9.980
VWAP
9.98
Vol
81.00
Mkt Cap
92.15M
Low
9.980
Amount
808.38
EV/EBITDA(TTM)
--
Total Shares
9.39M
EV
24.47M
EV/OCF(TTM)
--
P/S(TTM)
--
LeonaBio, Inc., formerly Athira Pharma, Inc., is a clinical-stage biopharmaceutical company dedicated to the development of novel therapeutics for diseases with high unmet medical needs, including treatment-resistant metastatic breast cancer and amyotrophic lateral sclerosis (ALS). The Company's lead drug candidates, lasofoxifene and ATH-1105, are novel, small molecule therapies with the potential to address devastating diseases where current treatment options are limited or ineffective. ATH-1105 is a novel, orally available, brain-penetrant, next-generation small-molecule drug candidate designed to positively modulate the neurotrophic HGF system for potential treatment of neurodegenerative diseases, including ALS, Alzheimer's disease, and Parkinson's disease. Lasofoxifene is a novel, nonsteroidal SERM with a binding profile, designed to confer potent activity against both wild-type and mutant estrogen receptors, including the clinically significant ESR1 mutations.
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Events Timeline

(ET)
2026-02-03
07:10:00
LeonaBio Appoints Mark Kubik as Chief Business Officer
select
2026-01-20 (ET)
2026-01-20
16:50:00
LeonaBio Files to Sell 5.5M Shares of Common Stock
select

News

seekingalpha
9.5
05-07seekingalpha
Athira Pharma Q1 Earnings Beat Expectations
  • Earnings Highlights: Athira Pharma reported a Q1 GAAP EPS of -$1.73, beating expectations by $0.77, indicating an improvement in financial performance despite still being in the red.
  • Cash Position: As of March 31, 2026, the company had $67.7 million in cash, cash equivalents, and investments, down from $88.3 million as of December 31, 2025, reflecting tightening operational funds.
  • Increased Operating Expenses: The net cash used in operations for Q1 2026 was $20.9 million, significantly higher than $14.7 million in Q1 2025, highlighting increased pressure on the company’s R&D and operational expenditures.
  • Financing Plans: LeonaBio announced a $90 million private placement financing related to its license agreement with Sermonix, with warrants potentially providing an additional $146 million to support development through key clinical and regulatory milestones.
seekingalpha
9.5
05-07seekingalpha
Athira Pharma Q1 Earnings Beat Expectations
  • Earnings Highlights: Athira Pharma reported a Q1 GAAP EPS of -$1.73, beating expectations by $0.77, indicating some improvement in financial performance despite still being in a loss position.
  • Cash Position: As of March 31, 2026, the company's cash, cash equivalents, and investments totaled $67.7 million, down from $88.3 million as of December 31, 2025, reflecting tightening liquidity.
  • Increased Operating Expenses: The net cash used in operations for Q1 was $20.9 million, up from $14.7 million in Q1 2025, indicating increased pressure on spending in R&D and operations, which may affect future financial health.
  • Financing Strategy: LeonaBio announced a $90 million private placement financing related to its December 2025 license agreement with Sermonix, with warrants potentially providing an additional $146 million to support development through key clinical and regulatory milestones, demonstrating a proactive approach to future growth.
Newsfilter
5.0
05-07Newsfilter
LeonaBio Appoints New Board Members to Drive Growth
  • New Board Members: LeonaBio appointed Fred Callori, Natalie Holles, and Peter B. Silverman to its Board of Directors effective May 5, 2026, aiming to leverage their extensive experience in oncology and neurology to advance the company's clinical pipeline.
  • Rich Leadership Experience: The new board members bring significant leadership expertise in the biopharmaceutical sector, with Callori as a partner at Perceptive Advisors, Holles as CEO of Aura Biosciences, and Silverman as COO of Merus N.V., providing robust support for LeonaBio's strategic execution.
  • Appreciation for Former Director: LeonaBio expressed gratitude to former board member John Fluke, who retired on May 4, 2026, after serving since 2014, acknowledging his contributions that significantly shaped the company's development over the past decade.
  • Company Vision: LeonaBio is dedicated to developing innovative therapies for high unmet medical needs, and the new board members are expected to help the company achieve greater breakthroughs in treating treatment-resistant metastatic breast cancer and amyotrophic lateral sclerosis (ALS).
seekingalpha
9.5
03-27seekingalpha
LeonaBio Reports FY 2025 Financial Results
  • Earnings Loss: LeonaBio reported a GAAP EPS of -$24.70 for FY 2025, indicating significant challenges in profitability that could negatively impact investor confidence and stock performance.
  • Improved Cash Position: As of December 31, 2025, the company's cash, cash equivalents, and investments totaled $88.3 million, a substantial increase from $51.3 million in 2024, suggesting enhanced financial management and increased operational flexibility for future endeavors.
  • Reduced Operating Cash Flow: The net cash used in operations for FY 2025 was $45.7 million, a significant decrease from $97.2 million in 2024, reflecting progress in cost control and operational efficiency, potentially laying the groundwork for future profitability.
  • Corporate Restructuring: LeonaBio is undergoing a name and ticker symbol change, a strategic move aimed at rebranding and attracting new investors, thereby enhancing market competitiveness and shareholder value.
Newsfilter
8.5
03-26Newsfilter
LeonaBio Secures License for Lasofoxifene Development Program
  • Successful Financing: LeonaBio secured $90 million in private placement financing, with cash-exercisable warrants potentially providing an additional $146 million, which will robustly support the development of Lasofoxifene through key clinical and regulatory milestones, ensuring financial stability for the company.
  • Clinical Trial Progress: The company expects to complete enrollment for the Phase 3 clinical trial of Lasofoxifene by Q4 2026, with topline data anticipated in the second half of 2027, offering a new treatment option for patients with ER-positive, HER2-negative, ESR1-mutated metastatic breast cancer, which holds significant market potential.
  • Drug Development Strategy: As a novel selective estrogen receptor modulator, Lasofoxifene aims to target ESR1 mutations in metastatic breast cancer patients, potentially becoming the preferred second-line treatment and altering the standard of care in this field, enhancing the company's competitive position in the biopharmaceutical market.
  • New Drug Candidate ATH-1105: LeonaBio plans to initiate a Phase 2 proof-of-concept study for ATH-1105 in ALS patients in the second half of 2026, demonstrating the company's diversified strategy and innovative capabilities in the neurodegenerative disease sector.
moomoo
9.0
03-26moomoo
LEONABIO INC ANTICIPATES COMPLETION OF PHASE 3 LASOFOXIFENE TRIAL ENROLLMENT BY Q4 2026, WITH TOPLINE RESULTS EXPECTED IN SECOND HALF OF 2027
  • Phase 3 Trial Expectations: Leonabiol is anticipating the completion of Phase 3 trials for its product by the second quarter of 2026.
  • Topline Data Release: The company plans to release topline data from the trials in the second half of 2027.
Wall Street analysts forecast LONA stock price to rise
0 Analyst Rating
Wall Street analysts forecast LONA stock price to rise
0 Buy
0 Hold
0 Sell
Current: 0.000
sliders
Low
Averages
High
Current: 0.000
sliders
Low
Averages
High
Piper Sandler
Overweight
initiated
$20
AI Analysis
2026-05-27
New
Reason
Piper Sandler
Price Target
$20
AI Analysis
2026-05-27
New
initiated
Overweight
Reason
Piper Sandler initiated coverage of LeonaBio with an Overweight rating and $20 price target. The company is advancing lasofoxifene, a selective estrogen receptor modulator for treatment of ER+/HER2- metastatic breast cancer, the analyst tells investors in a research note. Piper views LeonaBio as a late clinical stage biotech company that is well positioned to compete in the large metastatic breast cancer market.
Mizuho
Outperform
maintain
$10 -> $16
2026-04-06
Reason
Mizuho
Price Target
$10 -> $16
2026-04-06
maintain
Outperform
Reason
Mizuho raised the firm's price target on LeonaBio to $16 from $10 and keeps an Outperform rating on the shares post the Q4 report. The firm views LeonaBio as a "below-the-radar" and "underappreciated" name. The analyst increased its peak sales estimates for lasofoxifene after analyzing the competitive landscape and the breast cancer opportunity.
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Valuation Metrics

The current forward P/E ratio for LeonaBio Inc (LONA.O) is 0.00, compared to its 5-year average forward P/E of --. For a more detailed relative valuation and DCF analysis to assess LeonaBio Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
Current PE
0.00
Overvalued PE
Undervalued PE

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
Undervalued EV/EBITDA

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
Current PS
0.00
Overvalued PS
Undervalued PS

Financials

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Whales Holding LONA

C
Commodore Capital LP
Holding
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+18.34%
3M Return
T
TCG Crossover Management, LLC
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+11.54%
3M Return
N
New Enterprise Associates, Inc.
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-1.78%
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Frequently Asked Questions

What is LeonaBio Inc (LONA) stock price today?

The current price of LONA is 9.98 USD — it has increased 3.53

What is LeonaBio Inc (LONA)'s business?

LeonaBio, Inc., formerly Athira Pharma, Inc., is a clinical-stage biopharmaceutical company dedicated to the development of novel therapeutics for diseases with high unmet medical needs, including treatment-resistant metastatic breast cancer and amyotrophic lateral sclerosis (ALS). The Company's lead drug candidates, lasofoxifene and ATH-1105, are novel, small molecule therapies with the potential to address devastating diseases where current treatment options are limited or ineffective. ATH-1105 is a novel, orally available, brain-penetrant, next-generation small-molecule drug candidate designed to positively modulate the neurotrophic HGF system for potential treatment of neurodegenerative diseases, including ALS, Alzheimer's disease, and Parkinson's disease. Lasofoxifene is a novel, nonsteroidal SERM with a binding profile, designed to confer potent activity against both wild-type and mutant estrogen receptors, including the clinically significant ESR1 mutations.

What is the price predicton of LONA Stock?

Wall Street analysts forecast LONA stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for LONA is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is LeonaBio Inc (LONA)'s revenue for the last quarter?

LeonaBio Inc revenue for the last quarter amounts to -18.14M USD, increased 90.26

What is LeonaBio Inc (LONA)'s earnings per share (EPS) for the last quarter?

LeonaBio Inc. EPS for the last quarter amounts to -20903000.00 USD, increased 42.54

How many employees does LeonaBio Inc (LONA). have?

LeonaBio Inc (LONA) has 19 emplpoyees as of May 29 2026.

What is LeonaBio Inc (LONA) market cap?

Today LONA has the market capitalization of 92.15M USD.