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KYNB Overview

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0.000
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Intellectia

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High
7.270
Open
7.237
VWAP
7.26
Vol
13.04K
Mkt Cap
29.54M
Low
7.220
Amount
94.70K
EV/EBITDA(TTM)
--
Total Shares
4.05M
EV
-6.90M
EV/OCF(TTM)
--
P/S(TTM)
4.34
Kyntra Bio, Inc., formerly FibroGen, Inc., is a biopharmaceutical company. The Company is focused on development of novel therapies in oncology and rare disease. The Company continues to evaluate the development plan for the Phase III trial of roxadustat in anemia associated with lower-risk myelodysplastic syndrome (LR-MDS) in the U.S. FG-3246 (also known as FOR46), a first-in-class antibody-drug conjugate (ADC) targeting CD46, is in Phase II development for the treatment of metastatic castration-resistant prostate cancer. This program also includes the development of FG-3180, an associated CD46-targeted PET biomarker. Roxadustat (EVRENZO) is approved in Europe, Japan, and numerous other countries for the treatment of anemia in chronic kidney disease (CKD) patients on dialysis and not on dialysis.
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Events Timeline

(ET)
2026-02-23
17:20:00
Kyntra Bio to Present FG-3246 Data at ASCO GU Conference
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News

NASDAQ.COM
9.5
03-17NASDAQ.COM
Kyntra Bio Reports Q4 and Full Year 2025 Financial Results with Losses
  • Financial Decline: Kyntra Bio reported a net loss of $14.22 million in Q4 2025, translating to a loss of $3.51 per share, compared to a net profit of $17.98 million or $4.46 per share in the same quarter last year, indicating a significant decline in profitability.
  • Annual Performance Shift: For the full year 2025, the company achieved a net profit of $183.45 million, or $45.37 per share, a substantial recovery from a net loss of $47.58 million in the previous year, although it still faced ongoing operational losses.
  • Revenue Drop: Total revenue for Q4 decreased to $1.28 million from $3.14 million year-over-year, while annual revenue fell from $29.62 million to $6.44 million, reflecting competitive pressures and challenges in product sales.
  • Pipeline Developments: Kyntra Bio is advancing several investigational products, including Roxadustat for anemia in chronic kidney disease, FG-3246 for metastatic castration-resistant prostate cancer, and FG-3180 as a diagnostic PET imaging agent, demonstrating the company's commitment to innovation in drug development.
seekingalpha
9.5
03-16seekingalpha
FibroGen Q4 Earnings Report Analysis
  • Earnings Performance: FibroGen reported a Q4 GAAP EPS of -$3.51, beating expectations by $0.37, but revenue of $1.27 million fell 59% year-over-year, indicating significant challenges in revenue growth.
  • Annual Revenue Comparison: Total revenue from continuing operations for 2025 was $6.4 million, a sharp decline from $29.6 million in 2024, reflecting substantial difficulties in market competition and product sales.
  • Net Loss Situation: The net loss for Q4 2025 was $14.6 million, or $3.61 per share, which is a significant increase from a net loss of $8.7 million and $2.15 per share in the same quarter last year, indicating a deterioration in the company's financial health.
  • Cash Flow Status: As of December 31, 2025, FibroGen reported $109.4 million in cash, cash equivalents, investments, and accounts receivable, with expectations that these funds will be sufficient to support operating plans into 2028, despite ongoing losses.
seekingalpha
9.5
03-15seekingalpha
FibroGen to Announce Q4 Earnings on March 16
  • Earnings Announcement Schedule: FibroGen is set to release its Q4 earnings on March 16 after market close, drawing significant attention from investors regarding its performance.
  • EPS Expectations: The consensus EPS estimate stands at -$3.88, reflecting a staggering year-over-year decline of 2255.6%, indicating severe profitability challenges for the company.
  • Revenue Forecast Decline: The anticipated revenue for Q4 is $1.67 million, representing a 46.1% year-over-year decrease, highlighting the company's struggles in market competition and product sales.
  • Market Reaction Anticipation: Given the poor earnings outlook, investors may react negatively to FibroGen's stock price, potentially impacting market confidence and the company's investment appeal.
Benzinga
9.0
02-24Benzinga
Kyntra Bio Reports Phase 1b/2 Data for Prostate Cancer Treatment
  • Clinical Trial Results: Kyntra Bio's Phase 1b/2 study of FG-3246 in combination with enzalutamide for metastatic castration-resistant prostate cancer showed a 21% overall response rate among 44 patients, with a notable 40% response rate in those previously treated with only one androgen receptor pathway inhibitor, indicating the potential of this combination therapy.
  • Survival Data: The study reported a median radiographic progression-free survival (rPFS) of 10.1 months for patients, while the overall cohort had a median rPFS of 7.0 months, suggesting FG-3246 may positively impact patient survival and provide new treatment options.
  • Safety Analysis: The combination therapy demonstrated a safety profile similar to that of previous monotherapy trials, with the use of G-CSF prophylaxis mitigating the risk of neutropenia, indicating the clinical feasibility of this treatment approach.
  • Market Outlook: While William Blair analysts expressed encouragement regarding the initial results of FG-3246, they also noted the need for additional data to assess its long-term potential in the highly competitive prostate cancer market, thus maintaining a Market Perform rating on Kyntra shares.
Newsfilter
9.0
02-23Newsfilter
FG-3246 and Enzalutamide Combination Therapy Shows Promising Results
  • Clinical Trial Results: The combination therapy of FG-3246 and enzalutamide demonstrated a median radiographic progression-free survival (rPFS) of 7.0 months in biomarker-unselected metastatic castration-resistant prostate cancer patients, with a notable 10.1 months rPFS in patients who progressed after only one prior ARPI, indicating its potential in earlier lines of therapy.
  • Biomarker Potential: Higher tumor uptake of FG-3180 showed a trend towards a higher probability of PSA50 response (p=0.053), highlighting FG-3180's potential as a patient selection biomarker, which may play a crucial role in future clinical trials.
  • Safety Analysis: The safety profile of the combination therapy was similar to that observed in the previous FG-3246 monotherapy trial, with the risk of neutropenia effectively mitigated through G-CSF prophylaxis, while common treatment-related adverse events included fatigue, peripheral neuropathy, and anorexia.
  • Future Outlook: The Phase 2 monotherapy trial of FG-3246 is on track for interim analysis in the second half of 2026, further validating its application potential in metastatic castration-resistant prostate cancer and exploring the efficacy of FG-3180 as a biomarker.
Wall Street analysts forecast KYNB stock price to rise
2 Analyst Rating
Wall Street analysts forecast KYNB stock price to rise
1 Buy
1 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
43.00
Averages
43.00
High
43.00
Current: 0.000
sliders
Low
43.00
Averages
43.00
High
43.00
No data

No data

Valuation Metrics

The current forward P/E ratio for Kyntra Bio Inc (KYNB.O) is 61.35, compared to its 5-year average forward P/E of 71.77. For a more detailed relative valuation and DCF analysis to assess Kyntra Bio Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PE
71.77
Current PE
61.35
Overvalued PE
79.53
Undervalued PE
64.02

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average EV/EBITDA
0.45
Current EV/EBITDA
0.36
Overvalued EV/EBITDA
0.54
Undervalued EV/EBITDA
0.37

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.97
Current PS
5.48
Overvalued PS
6.58
Undervalued PS
5.37

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Frequently Asked Questions

What is Kyntra Bio Inc (KYNB) stock price today?

The current price of KYNB is 7.3 USD — it has increased 5.49

What is Kyntra Bio Inc (KYNB)'s business?

Kyntra Bio, Inc., formerly FibroGen, Inc., is a biopharmaceutical company. The Company is focused on development of novel therapies in oncology and rare disease. The Company continues to evaluate the development plan for the Phase III trial of roxadustat in anemia associated with lower-risk myelodysplastic syndrome (LR-MDS) in the U.S. FG-3246 (also known as FOR46), a first-in-class antibody-drug conjugate (ADC) targeting CD46, is in Phase II development for the treatment of metastatic castration-resistant prostate cancer. This program also includes the development of FG-3180, an associated CD46-targeted PET biomarker. Roxadustat (EVRENZO) is approved in Europe, Japan, and numerous other countries for the treatment of anemia in chronic kidney disease (CKD) patients on dialysis and not on dialysis.

What is the price predicton of KYNB Stock?

Wall Street analysts forecast KYNB stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for KYNB is43.00 USD with a low forecast of 43.00 USD and a high forecast of 43.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Kyntra Bio Inc (KYNB)'s revenue for the last quarter?

Kyntra Bio Inc revenue for the last quarter amounts to 1.28M USD, decreased -59.27

What is Kyntra Bio Inc (KYNB)'s earnings per share (EPS) for the last quarter?

Kyntra Bio Inc. EPS for the last quarter amounts to -3.51 USD, decreased -178.70

How many employees does Kyntra Bio Inc (KYNB). have?

Kyntra Bio Inc (KYNB) has 34 emplpoyees as of April 09 2026.

What is Kyntra Bio Inc (KYNB) market cap?

Today KYNB has the market capitalization of 29.54M USD.