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HCWB Overview

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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
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ET
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Intellectia

Loading chart...

High
0.336
Open
0.320
VWAP
0.32
Vol
272.20K
Mkt Cap
2.21M
Low
0.302
Amount
87.81K
EV/EBITDA(TTM)
--
Total Shares
6.73M
EV
7.07M
EV/OCF(TTM)
--
P/S(TTM)
12.98
HCW Biologics Inc. is a clinical-stage biopharmaceutical company. It is focused on discovering and developing novel immunotherapies to lengthen the health span by disrupting the link between chronic, low-grade inflammation, and age-related diseases, such as cancer, cardiovascular diseases, diabetes, neurodegenerative diseases, autoimmune diseases, as well as other conditions. It has developed a Tissue factOr-Based fusion (TOBI) discovery platform to generate designer, novel multi-functional fusion molecules with immunotherapeutic properties. Its lead product candidates include HCW9218 and HCW9302. HCW9218 is a clinical-stage bifunctional molecule that is designed to impact senescence by reducing senescent cells. The Company is prepared to progress HCW9218 in Phase II clinical trials for non-oncology indications.HCW9302 is designed to activate and expand regulatory T cells, which deactivate inflammasomes. Its other product candidates include HCW9201, HCW9206, HCW11-006, and others.
Show More

Events Timeline

(ET)
2026-04-27
09:20:00
HCW Biologics Advances Tetra-Valent T-Cell Engager Program
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2026-03-17 (ET)
2026-03-17
08:00:00
HCW Biologics Receives $7M License Fee
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2026-03-16 (ET)
2026-03-16
08:20:00
HCW Biologics Announces Groundbreaking Research Results
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2026-02-13 (ET)
2026-02-13
08:40:00
HCW Biologics and WY Biotech Sign $3.5 Million License Agreement
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2026-01-09 (ET)
2026-01-09
17:00:00
HCW Biologics Files to Sell 3.4M Shares of Common Stock
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2025-11-18 (ET)
2025-11-18
07:29:53
HCW Biologics Launches First-in-Human Trial for HW9302
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2025-11-10 (ET)
2025-11-10
07:47:59
HCW Biologics Provides New Update on Tetra-Valent ICI Program
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2025-11-07 (ET)
2025-11-07
07:06:38
HCW Biologics Reveals Data for TCE Program Utilizing TRBC Platform
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News

NASDAQ.COM
9.0
04-28NASDAQ.COM
HCW Biologics Reports Progress on Anti-Tumor Drug HCW11-018b
  • Clinical Research Progress: HCW Biologics presented positive developments regarding its anti-tumor drug HCW11-018b at the American Association for Cancer Research annual meeting, indicating significant achievements in clinical stages that may offer new solutions for solid tumor treatments.
  • Innovative Drug Mechanism: As the lead candidate of the Big BiTE program, HCW11-018b utilizes TRBC platform technology to enhance anti-tumor activity and tolerability through cis-binding techniques, demonstrating significant tumor shrinkage and prevention of metastasis in xenograft animal models.
  • Targeting Characteristics: The drug activates specifically within the tumor microenvironment, improving specificity and precision, which may reduce impacts on healthy cells, thereby enhancing treatment efficacy and safety.
  • Future Plans: HCW Biologics plans to file an Investigational New Drug (IND) application in the first half of 2027 to advance studies targeting pancreatic and ovarian cancers, reflecting the company's long-term strategic focus in the oncology sector.
Newsfilter
8.5
04-27Newsfilter
HCW Biologics Advances T-Cell Engager HCW11-018b for Pancreatic Cancer
  • Clinical Development Milestone: HCW Biologics showcased its lead T-Cell Engager HCW11-018b at the 2026 AACR Annual Meeting, demonstrating significant tumor shrinkage and metastasis prevention in mouse models, with an IND application expected in the first half of 2027 to seek clinical study authorization, marking a major advancement in pancreatic cancer treatment.
  • Mechanism Unveiled: New data reveals that HCW11-018b utilizes a cis-binding mechanism to regulate immune cell reactivity, activating only within the tumor microenvironment, which is expected to enhance efficacy and tolerability against human tumor cells, providing crucial insights for future therapeutic strategies.
  • Manufacturing Process Optimization: The tetra-valent T-Cell Engager employs a streamlined GMP manufacturing process, ensuring production efficiency and product quality, thereby accelerating the company's clinical development in solid tumors, particularly for pancreatic and ovarian cancers.
  • Strategic Focus: Dr. Hing C. Wong, the company's founder and CEO, highlighted HCW11-018b's remarkable anti-tumor activities and high tolerability in animal models, indicating its potential in treating chronic inflammation-related diseases, aligning with the company's long-term business development strategy.
NASDAQ.COM
9.5
04-01NASDAQ.COM
HCW Biologics Reports Q4 Results and Nasdaq Compliance Notice
  • Financial Performance Decline: HCW Biologics reported a net loss of $3.4 million for Q4 2025, contrasting sharply with a net gain of $2.2 million in the previous year, indicating significant financial deterioration that could undermine investor confidence.
  • Revenue Growth Stagnation: Although Q4 revenues increased from $27,000 to $390,000 primarily due to sales of licensed molecules to Wugen, the overall revenue growth fails to offset losses, reflecting ongoing market challenges faced by the company.
  • Compliance Risk Heightened: On March 26, 2026, the company received a notice from Nasdaq for failing to maintain a minimum bid price of $1 for 30 consecutive trading days, and due to a 1-for-40 reverse stock split in April 2025, it was not granted a 180-day compliance period, increasing future funding pressures.
  • Clinical Trial Progress: Preliminary human data from the Phase 1 dose-escalation study of HCW9302 is expected in the first half of 2026, and if it shows good tolerability, it could significantly improve upon existing IL-2 therapies, enhancing the company's competitive position in immunotherapy.
seekingalpha
9.5
03-31seekingalpha
HCW Biologics Reports Q4 2024 Financial Highlights
  • Revenue Comparison: HCW Biologics reported revenues of $394,804 for Q4 2024, contrasting sharply with just $27,010 in 2025, indicating a significant revenue decline that could impact future liquidity.
  • Net Income Shift: The company experienced a net loss of $3.4 million in Q4 2024, which turned into a net gain of $2.2 million in 2025, suggesting a successful financial turnaround that may boost investor confidence.
  • Increased R&D Spending: R&D expenses rose from $1.0 million in Q4 2024 to $1.3 million in 2025, reflecting the company's ongoing commitment to innovation and enhancing its competitive edge in the market.
  • Financial Overview: The financial data from HCW Biologics highlights significant changes between 2024 and 2025, showcasing the company's efforts to navigate market challenges and adjust its strategic direction.
Newsfilter
9.5
03-31Newsfilter
HCW Biologics Reports Q4 2025 Financial Results and Clinical Trial Updates
  • Clinical Trial Launch: HCW Biologics initiated its first-in-human clinical trial for HCW9302 on November 17, 2025, targeting autoimmune disorders like alopecia areata, with preliminary data expected in the first half of 2026, which could significantly enhance the company's market position if results are favorable.
  • License Agreement Revenue: As of March 16, 2026, the company received a $3.5 million upfront payment for the exclusive worldwide license of HCW11-006, with potential future milestone payments and double-digit royalties on product sales, providing crucial funding for ongoing R&D efforts.
  • Financial Performance: Revenue for Q4 2025 was $27,010, a sharp decline from $394,804 in Q4 2024, reflecting challenges during the company's transition, although R&D expenses increased by 27% to $1.3 million, indicating a commitment to new product development.
  • Legal Expense Recovery: In 2025, the company reported net legal expenses of $120,136, down from $148,949 in 2024, and received a $2 million insurance reimbursement for legal fees, which positively impacted the company's financial health.
NASDAQ.COM
7.5
03-17NASDAQ.COM
HCW Biologics Secures $7M License Fee from Beijing Trimmune
  • Agreement Value: HCW Biologics has secured a $7 million upfront license fee from Beijing Trimmune, which includes $3.5 million in cash and $3.5 million in equity, indicating market confidence in its immunotherapy developments.
  • Clinical Trial Responsibility: Trimmune will oversee the Phase 1 clinical trial of HCW11-006 in China, expected to commence in the first half of 2027, which will expedite product development while alleviating financial burdens on HCW Biologics.
  • Future Revenue Potential: HCW Biologics is entitled to receive double-digit royalties and significant milestone payments on future product sales, providing a potential revenue growth pathway for the company.
  • Market Reaction: Despite the agreement, HCW Biologics' stock fell 13.18% to $0.81, reflecting market concerns regarding the company's future prospects, particularly the uncertainties surrounding clinical trials and product commercialization.
Wall Street analysts forecast HCWB stock price to rise
1 Analyst Rating
Wall Street analysts forecast HCWB stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
8.00
Averages
8.00
High
8.00
Current: 0.000
sliders
Low
8.00
Averages
8.00
High
8.00
Maxim
Buy
downgrade
$120 -> $35
AI Analysis
2025-05-29
Reason
Maxim
Price Target
$120 -> $35
AI Analysis
2025-05-29
downgrade
Buy
Reason
Maxim lowered the firm's price target on HCW Biologics to $35 from $120 but keeps a Buy rating on the shares. The firm cites the company's Q1 results and equity raise in adjusting its price target but also notes that HCW has made considerable progress in shoring up its balance sheet and advancing its pipeline following a challenging legal issue and arbitration, the analyst tells investors in a research note. The company should now have the capital to advance its pipeline and drive a turnaround in share value, Maxim added.

Valuation Metrics

The current forward P/E ratio for HCW Biologics Inc (HCWB.O) is 0.00, compared to its 5-year average forward P/E of -2.82. For a more detailed relative valuation and DCF analysis to assess HCW Biologics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.82
Current PE
0.00
Overvalued PE
-1.03
Undervalued PE
-4.61

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.83
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.27
Undervalued EV/EBITDA
-1.93

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
249.36
Current PS
0.00
Overvalued PS
1113.40
Undervalued PS
-614.68

Financials

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Frequently Asked Questions

What is HCW Biologics Inc (HCWB) stock price today?

The current price of HCWB is 0.3287 USD — it has increased 2.5

What is HCW Biologics Inc (HCWB)'s business?

HCW Biologics Inc. is a clinical-stage biopharmaceutical company. It is focused on discovering and developing novel immunotherapies to lengthen the health span by disrupting the link between chronic, low-grade inflammation, and age-related diseases, such as cancer, cardiovascular diseases, diabetes, neurodegenerative diseases, autoimmune diseases, as well as other conditions. It has developed a Tissue factOr-Based fusion (TOBI) discovery platform to generate designer, novel multi-functional fusion molecules with immunotherapeutic properties. Its lead product candidates include HCW9218 and HCW9302. HCW9218 is a clinical-stage bifunctional molecule that is designed to impact senescence by reducing senescent cells. The Company is prepared to progress HCW9218 in Phase II clinical trials for non-oncology indications.HCW9302 is designed to activate and expand regulatory T cells, which deactivate inflammasomes. Its other product candidates include HCW9201, HCW9206, HCW11-006, and others.

What is the price predicton of HCWB Stock?

Wall Street analysts forecast HCWB stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for HCWB is8.00 USD with a low forecast of 8.00 USD and a high forecast of 8.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is HCW Biologics Inc (HCWB)'s revenue for the last quarter?

HCW Biologics Inc revenue for the last quarter amounts to 27.01K USD, decreased -93.16

What is HCW Biologics Inc (HCWB)'s earnings per share (EPS) for the last quarter?

HCW Biologics Inc. EPS for the last quarter amounts to -1.02 USD, decreased -68.03

How many employees does HCW Biologics Inc (HCWB). have?

HCW Biologics Inc (HCWB) has 25 emplpoyees as of May 11 2026.

What is HCW Biologics Inc (HCWB) market cap?

Today HCWB has the market capitalization of 2.21M USD.