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FDMT Overview

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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

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High
9.280
Open
8.880
VWAP
8.96
Vol
575.00K
Mkt Cap
1.08B
Low
8.730
Amount
5.15M
EV/EBITDA(TTM)
--
Total Shares
--
EV
-129.19M
EV/OCF(TTM)
--
P/S(TTM)
10.02K
4D Molecular Therapeutics, Inc. is a late-stage biotechnology company advancing durable and disease-targeted therapeutics. The Company's lead product candidate 4D-150 is designed to be a backbone therapy forming the foundation of treatment of blinding retinal vascular diseases by providing multi-year sustained delivery of anti-VEGF (aflibercept and anti-VEGF-C) with a single, safe, intravitreal injection, which substantially reduces the treatment burden associated with current bolus injections. Its lead indication for 4D-150 is wet age-related macular degeneration, which is in Phase III development, and second indication is diabetic macular edema. The Company is developing 4D-710 for the treatment of a range of people with cystic fibrosis independent of their specific CFTR mutation. 4D-710 is an investigational genetic medicine candidate using the A101 vector for the treatment of cystic fibrosis lung disease. The Company's non-core programs include 4D-175, 4D-725, and 4D-310.
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Events Timeline

(ET)
2026-02-09
08:30:00
4D Molecular Therapeutics Completes Enrollment for 4FRONT-1 Clinical Trial
select
2026-01-19 (ET)
2026-01-19
13:40:00
4D Molecular Therapeutics Grants 23,600 RSUs to New Employees
select
2026-01-07 (ET)
2026-01-07
08:20:00
4D Molecular Therapeutics Provides Corporate Update and Outlook for 2026
select
2025-12-17 (ET)
2025-12-17
07:10:00
4D Molecular Therapeutics Reports Positive Interim Data from 4D-710 Clinical Trial
select
2025-11-17 (ET)
2025-11-17
06:08:56
Kristian Humer Appointed CFO of 4D Molecular
select
2025-11-10 (ET)
2025-11-10
08:05:06
4D Molecular anticipates funding to last through the second half of 2028.
select
2025-11-10
08:04:25
4D Molecular Announces Q3 Earnings Per Share of $1.01, Exceeding Consensus Estimate of 98 Cents
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News

Globenewswire
5.0
01-17Globenewswire
4D Molecular Therapeutics Grants 23,600 RSUs to New Employees
  • Employee Incentive Program: On January 13, 2026, 4D Molecular Therapeutics' compensation committee granted 23,600 Restricted Stock Units (RSUs) to four new non-executive employees, aimed at attracting talent and enhancing team stability.
  • Equity Grant Context: The RSUs were awarded under the 2025 Employment Inducement Award Plan, approved by the board in February 2025, complying with Nasdaq Rule 5635(c)(4), reflecting the company's commitment to talent acquisition.
  • Product Development Progress: The company's lead product, 4D-150, is currently in Phase 3 trials, designed to provide multi-year sustained delivery of anti-VEGF through a single safe intravitreal injection, significantly reducing the treatment burden associated with current methods, showcasing transformative potential.
  • Gene Therapy Innovation: The second candidate, 4D-710, is the first known genetic medicine to successfully deliver and express the CFTR transgene in the lungs of cystic fibrosis patients, demonstrating the company's innovative capabilities and market potential in the therapeutic landscape.
Benzinga
2.0
2025-12-19Benzinga
Major Stocks Including BlackBerry, FedEx, and Nike Decline in Friday's Pre-Market Trading
  • U.S. Stock Futures: U.S. stock futures are mostly higher, with Nasdaq 100 futures gaining around 100 points on Friday.

  • BlackBerry Earnings Report: BlackBerry Ltd reported third-quarter revenue of $141.8 million, exceeding analyst expectations, but shares fell 4.6% in pre-market trading.

  • Other Stocks Declining: Several stocks, including Aimei Health Technology and Nike Inc, experienced significant declines in pre-market trading despite some reporting better-than-expected earnings.

  • Market Overview: The overall market sentiment is cautious, with various stocks showing downward trends following recent earnings reports and inflation data.

SeekingAlpha
9.0
2025-12-17SeekingAlpha
4D Molecular Shares Decline Following Initial Trial Results for Cystic Fibrosis Treatment
  • Stock Performance: 4D Molecular Therapeutics (FDMT) shares fell approximately 15% following the announcement of updated data from an early-stage trial for its cystic fibrosis therapy, 4D-710.

  • Trial Findings: The Phase 1 AEROW clinical trial indicated no new safety events in higher-dose groups, leading the company to select a specific dose for the upcoming Phase 2 trial.

  • Trial Design: The AEROW trial evaluated different doses of 4D-710 in adults with cystic fibrosis lung disease who cannot tolerate standard CFTR modulator therapy.

  • Future Plans: 4D Molecular Therapeutics aims to complete enrollment for the Phase 2 Dose-Expansion cohort by the first half of 2026, with a program update anticipated in the latter half of the year.

Globenewswire
9.0
2025-12-17Globenewswire
4D Molecular Therapeutics Reports Positive Interim Data for 4D-710 in Cystic Fibrosis Trial
  • Positive Clinical Data: 4D-710 demonstrated good tolerability and achieved physiologically relevant CFTR expression levels in the AEROW trial, indicating potential clinical benefits across multiple lung function and symptom measures, suggesting its promise as a cystic fibrosis treatment.
  • Patient Recruitment Progress: As of December 1, 2025, the AEROW trial has enrolled 16 cystic fibrosis patients, with no new safety events reported across different dose cohorts, underscoring the treatment's safety and efficacy.
  • Successful Dose Selection: The 2.5E14 vg dose cohort showed clinically meaningful activity across all endpoints, supporting its selection for the next phase and further optimizing the treatment regimen.
  • Future Milestones: The company anticipates completing enrollment of the AEROW Phase 2 Dose-Expansion cohort in H1 2026, further validating the efficacy of 4D-710, with plans to share additional updates in H2 2026.
NASDAQ.COM
9.0
2025-12-17NASDAQ.COM
4D Molecular Therapeutics Announces Encouraging Interim Phase 1 Results for 4D-710 in Cystic Fibrosis
  • Positive Interim Results: 4D Molecular Therapeutics reported encouraging interim results from its Phase 1 AEROW study for 4D-710, a gene therapy for cystic fibrosis, showing significant improvements in lung function over a one-year follow-up.

  • Durable CFTR Expression: The study demonstrated sustained CFTR transgene expression within the therapeutic range for at least one year, indicating potential long-term benefits for patients.

  • Future Plans: The company anticipates completing enrollment for the Phase 2 dose-expansion cohort by mid-2026, with an update on the program expected in the latter half of 2026.

  • Stock Performance: Following the announcement, FDMT shares rose by 5.21%, closing at $11.52.

Globenewswire
5.0
2025-12-12Globenewswire
4D Molecular Therapeutics Grants 13,800 RSUs to New Employees Under Inducement Plan
  • Employee Incentive Program: On December 9, 2025, 4D Molecular Therapeutics granted 13,800 Restricted Stock Units (RSUs) to three new non-executive employees, aimed at attracting new talent through the 2025 Employment Inducement Award Plan, thereby enhancing the company's human resource competitiveness.
  • Board Approval: The plan was approved by the board in February 2025, complying with Nasdaq Global Market Rule 5635(c)(4), indicating the company's commitment to attracting and retaining key talent, which will further drive its biotechnology innovations.
  • Product Development Context: The company's lead product candidate, 4D-150, is currently in Phase 3 clinical trials, designed to provide multi-year sustained anti-VEGF delivery through a single safe intravitreal injection, significantly reducing the treatment burden associated with current methods and improving patient experience.
  • Market Potential: With the development of product candidates like 4D-150 and 4D-710, the company is poised to achieve breakthroughs in treating blinding retinal vascular diseases and cystic fibrosis, further solidifying its market position in the biotechnology sector.
Wall Street analysts forecast FDMT stock price to rise
6 Analyst Rating
Wall Street analysts forecast FDMT stock price to rise
5 Buy
0 Hold
1 Sell
Moderate Buy
Current: 0.000
sliders
Low
17.00
Averages
29.40
High
38.00
Current: 0.000
sliders
Low
17.00
Averages
29.40
High
38.00
Barclays
initiated
$33
AI Analysis
2026-01-27
Reason
Barclays
Price Target
$33
AI Analysis
2026-01-27
initiated
Reason
Barclays assumed coverage of 4D Molecular with an Overweight rating and $33 price target. Barclays initiated coverage of 12 biotech stocks and assumed coverage of 11 with a positive view of the industry. The analyst likes the setup for the group in 2026. Many biotech stocks remain undervalued, the analyst tells investors in a research note. The firm expects continued mergers and acquisitions, "strong" underlying fundamentals, and less of a focus on drug pricing to act as "significant tailwinds."
RBC Capital
Lisa Walter
Outperform
maintain
$26 -> $32
2025-11-11
Reason
RBC Capital
Lisa Walter
Price Target
$26 -> $32
2025-11-11
maintain
Outperform
Reason
RBC Capital analyst Lisa Walter raised the firm's price target on 4D Molecular to $32 from $26 and keeps an Outperform rating on the shares after its Q3 results. The company's current cash position of $372M plus additional funds from the recent APAC deal with Otsuka and capital raise should extend the runway by 6 months into the second half of FY28 and fund both wAMD and DME pivotals, the analyst tells investors in a research note, adding that the recent funding "adds some cushion to the runway".
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Valuation Metrics

The current forward P/E ratio for 4D Molecular Therapeutics Inc (FDMT.O) is -1.26, compared to its 5-year average forward P/E of -5.43. For a more detailed relative valuation and DCF analysis to assess 4D Molecular Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.43
Current PE
-1.26
Overvalued PE
-2.37
Undervalued PE
-8.50

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.71
Current EV/EBITDA
1.44
Overvalued EV/EBITDA
0.32
Undervalued EV/EBITDA
-5.73

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
119.97
Current PS
56.68
Overvalued PS
210.90
Undervalued PS
29.03

Financials

AI Analysis
Annual
Quarterly

Whales Holding FDMT

B
BVF Partners L.P.
Holding
FDMT
+6.57%
3M Return
R
RA Capital Management, L.P.
Holding
FDMT
+4.57%
3M Return
N
Novo Holdings A/S
Holding
FDMT
-22.63%
3M Return

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Frequently Asked Questions

What is 4D Molecular Therapeutics Inc (FDMT) stock price today?

The current price of FDMT is 8.87 USD — it has increased 1.6

What is 4D Molecular Therapeutics Inc (FDMT)'s business?

4D Molecular Therapeutics, Inc. is a late-stage biotechnology company advancing durable and disease-targeted therapeutics. The Company's lead product candidate 4D-150 is designed to be a backbone therapy forming the foundation of treatment of blinding retinal vascular diseases by providing multi-year sustained delivery of anti-VEGF (aflibercept and anti-VEGF-C) with a single, safe, intravitreal injection, which substantially reduces the treatment burden associated with current bolus injections. Its lead indication for 4D-150 is wet age-related macular degeneration, which is in Phase III development, and second indication is diabetic macular edema. The Company is developing 4D-710 for the treatment of a range of people with cystic fibrosis independent of their specific CFTR mutation. 4D-710 is an investigational genetic medicine candidate using the A101 vector for the treatment of cystic fibrosis lung disease. The Company's non-core programs include 4D-175, 4D-725, and 4D-310.

What is the price predicton of FDMT Stock?

Wall Street analysts forecast FDMT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for FDMT is29.40 USD with a low forecast of 17.00 USD and a high forecast of 38.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is 4D Molecular Therapeutics Inc (FDMT)'s revenue for the last quarter?

4D Molecular Therapeutics Inc revenue for the last quarter amounts to 14.00K USD, decreased -50.00

What is 4D Molecular Therapeutics Inc (FDMT)'s earnings per share (EPS) for the last quarter?

4D Molecular Therapeutics Inc. EPS for the last quarter amounts to -0.86 USD, increased 30.30

How many employees does 4D Molecular Therapeutics Inc (FDMT). have?

4D Molecular Therapeutics Inc (FDMT) has 227 emplpoyees as of March 11 2026.

What is 4D Molecular Therapeutics Inc (FDMT) market cap?

Today FDMT has the market capitalization of 1.08B USD.